Carbenicillin (BioDeep_00000006361)

human metabolite blood metabolite Chemicals and Drugs

代谢物信息卡片

(2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

化学式: C17H18N2O6S (378.0885528)
中文名称: 羧苄西林
谱图信息: 最多检出来源 Mentha canadensis(plant) 57.45%

分子结构信息

SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)O)C(=O)O)C
InChI: InChI=1S/C17H18N2O6S/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25)/t9?,10-,11+,14-/m1/s1

描述信息

Carbenicillin is only found in individuals that have used or taken this drug. It is a broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. [PubChem]Free carbenicillin is the predominant pharmacologically active fraction of the salt. Carbenicillin exerts its antibacterial activity by interference with final cell wall synthesis of susceptible bacteria. Penicillins acylate the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation of the enzyme prevents the formation of a cross-link of two linear peptidoglycan strands, inhibiting the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that carbenicillin interferes with an autolysin inhibitor.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01C - Beta-lactam antibacterials, penicillins > J01CA - Penicillins with extended spectrum
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

33 个代谢物同义名

(2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid; N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamate; Sanfer brand OF carbenicillin disodium salt; CSL Brand OF carbenicillin disodium salt; alpha-Phenyl(carboxymethylpenicillin); a-Phenyl(carboxymethylpenicillin); Α-phenyl(carboxymethylpenicillin); Carboxybenzylpenicillin acid; alpha-Carboxybenzylpencillin; Penicillin, carboxybenzyl; Α-carboxybenzylpencillin; Carboxybenzyl penicillin; a-Carboxybenzylpencillin; Carboxybenzylpenicillin; Disodium, carbenicillin; Carbenicillin disodium; Sodium carbenicillin; Carbenicillinum; Carbenicillina; Carbenicilline; Carbenicilina; Carbenicillin; Microcillin; Anabactyl; Carbapen; Carbecin; Pyopen; Geopen; CBPC; Carbenicillin

数据库引用编号

18 个数据库交叉引用编号

ChEBI: CHEBI:3393
KEGG: C06869
KEGGdrug: D07614
PubChem: 20824
PubChem: 2560
HMDB: HMDB0014717
Metlin: METLIN3946
DrugBank: DB00578
ChEMBL: CHEMBL1214
Wikipedia: Carbenicillin
MeSH: Carbenicillin
chemspider: 19599
CAS: 4697-36-3
PMhub: MS000019389
PubChem: 9086
NIKKAJI: J3.066J
RefMet: Carbenicillin
KNApSAcK: 3393

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

9606 - Homo sapiens: -
4081 - Solanum lycopersicum: 10.1038/SDATA.2014.29

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Anbu Mozhi Thamizhchelvan, Abdul-Razak Masoud, Shanchun Su, Yan Lu, Hongying Peng, Yuichi Kobayashi, Yu Wang, Nathan K Archer, Song Hong. Bactericidal Efficacy of the Combination of Maresin-like Proresolving Mediators and Carbenicillin Action on Biofilm-Forming Burn Trauma Infection-Related Bacteria. International journal of molecular sciences. 2024 Feb; 25(5):. doi: 10.3390/ijms25052792. [PMID: 38474038]
Marco E Gudiño, Noel Blanco-Touriñán, Vicent Arbona, Aurelio Gómez-Cadenas, Miguel A Blázquez, Federico Navarro-García. β-Lactam Antibiotics Modify Root Architecture and Indole Glucosinolate Metabolism in Arabidopsis thaliana. Plant & cell physiology. 2018 Oct; 59(10):2086-2098. doi: 10.1093/pcp/pcy128. [PMID: 29986082]
M Ali Fadel, Reem H El-Gebaly, Shaimaa A Mohamed, Ashraf M M Abdelbacki. Biophysical control of the growth of Agrobacterium tumefaciens using extremely low frequency electromagnetic waves at resonance frequency. Biochemical and biophysical research communications. 2017 12; 494(1-2):365-371. doi: 10.1016/j.bbrc.2017.10.008. [PMID: 28988110]
Anu A Thoppil, Sinjan Choudhary, Nand Kishore. Competitive binding of anticancer drugs 5-fluorouracil and cyclophosphamide with serum albumin: Calorimetric insights. Biochimica et biophysica acta. 2016 May; 1860(5):917-929. doi: 10.1016/j.bbagen.2016.01.026. [PMID: 26854955]
J X Juan, X H Yu, X M Jiang, Z Gao, Y Zhang, W Li, Y D Duan, G Yang. Agrobacterium-mediated transformation of tomato with the ICE1 transcription factor gene. Genetics and molecular research : GMR. 2015 Jan; 14(1):597-608. doi: 10.4238/2015.january.30.1. [PMID: 25729995]
Heather K Allen, Ran An, Jo Handelsman, Luke A Moe. A response regulator from a soil metagenome enhances resistance to the β-lactam antibiotic carbenicillin in Escherichia coli. PloS one. 2015; 10(3):e0120094. doi: 10.1371/journal.pone.0120094. [PMID: 25782011]
John R Zupan, Todd A Cameron, James Anderson-Furgeson, Patricia C Zambryski. Dynamic FtsA and FtsZ localization and outer membrane alterations during polar growth and cell division in Agrobacterium tumefaciens. Proceedings of the National Academy of Sciences of the United States of America. 2013 May; 110(22):9060-5. doi: 10.1073/pnas.1307241110. [PMID: 23674672]
Aaron T Wolman, Michael R Gionfriddo, Gregory A Heindel, Paran Mukhija, Sarah Witkowski, Ajay Bommareddy, Adam L Vanwert. Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics. Drug metabolism and disposition: the biological fate of chemicals. 2013 Apr; 41(4):791-800. doi: 10.1124/dmd.112.049569. [PMID: 23344796]
Aurijit Sarkar, Kelcey C Anderson, Glen E Kellogg. Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics. European journal of medicinal chemistry. 2012 Jun; 52(?):98-110. doi: 10.1016/j.ejmech.2012.03.008. [PMID: 22483632]
Elizabeth Mortimer, James M Maclean, Sandiswa Mbewana, Amelia Buys, Anna-Lise Williamson, Inga I Hitzeroth, Edward P Rybicki. Setting up a platform for plant-based influenza virus vaccine production in South Africa. BMC biotechnology. 2012 Apr; 12(?):14. doi: 10.1186/1472-6750-12-14. [PMID: 22536810]
Jessica C Seeliger, Cynthia M Holsclaw, Michael W Schelle, Zsofia Botyanszki, Sarah A Gilmore, Sarah E Tully, Michael Niederweis, Benjamin F Cravatt, Julie A Leary, Carolyn R Bertozzi. Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. The Journal of biological chemistry. 2012 Mar; 287(11):7990-8000. doi: 10.1074/jbc.m111.315473. [PMID: 22194604]
Aneta Gerszberg, Aneta Wiktorek-Smagur, Katarzyna Hnatuszko-Konka, Piotr Łuchniak, Andrzej K Kononowicz. Expression of recombinant staphylokinase, a fibrin-specific plasminogen activator of bacterial origin, in potato (Solanum tuberosum L.) plants. World journal of microbiology & biotechnology. 2012 Mar; 28(3):1115-23. doi: 10.1007/s11274-011-0912-2. [PMID: 22347774]
Stuart Kyle, Kier A R James, Michael J McPherson. Recombinant production of the therapeutic peptide lunasin. Microbial cell factories. 2012 Feb; 11(?):28. doi: 10.1186/1475-2859-11-28. [PMID: 22376274]
Ruth C Martin, Kira Glover-Cutter, James C Baldwin, James E Dombrowski. Identification and characterization of a salt stress-inducible zinc finger protein from Festuca arundinacea. BMC research notes. 2012 Jan; 5(?):66. doi: 10.1186/1756-0500-5-66. [PMID: 22272737]
Takamitsu Kurusu, Daisuke Nishikawa, Yukari Yamazaki, Mariko Gotoh, Masataka Nakano, Haruyasu Hamada, Takuya Yamanaka, Kazuko Iida, Yuko Nakagawa, Hikaru Saji, Kazuo Shinozaki, Hidetoshi Iida, Kazuyuki Kuchitsu. Plasma membrane protein OsMCA1 is involved in regulation of hypo-osmotic shock-induced Ca2+ influx and modulates generation of reactive oxygen species in cultured rice cells. BMC plant biology. 2012 Jan; 12(?):11. doi: 10.1186/1471-2229-12-11. [PMID: 22264357]
Ramar Perumal Samy, Ponnampalam Gopalakrishnakone, Vincent Tk Chow. Therapeutic application of natural inhibitors against snake venom phospholipase A(2). Bioinformation. 2012; 8(1):48-57. doi: 10.6026/97320630008048. [PMID: 22359435]
Jessie Fernandez, Janet D Wright, David Hartline, Cristian F Quispe, Nandakumar Madayiputhiya, Richard A Wilson. Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection. PLoS genetics. 2012; 8(5):e1002673. doi: 10.1371/journal.pgen.1002673. [PMID: 22570632]
Joshua I Park, Eric J Steen, Helcio Burd, Sophia S Evans, Alyssa M Redding-Johnson, Tanveer Batth, Peter I Benke, Patrik D'haeseleer, Ning Sun, Kenneth L Sale, Jay D Keasling, Taek Soon Lee, Christopher J Petzold, Aindrila Mukhopadhyay, Steven W Singer, Blake A Simmons, John M Gladden. A thermophilic ionic liquid-tolerant cellulase cocktail for the production of cellulosic biofuels. PloS one. 2012; 7(5):e37010. doi: 10.1371/journal.pone.0037010. [PMID: 22649505]
Christian Löw, Caroline Jegerschöld, Michael Kovermann, Per Moberg, Pär Nordlund. Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1. PloS one. 2012; 7(6):e38244. doi: 10.1371/journal.pone.0038244. [PMID: 22675529]
Natarajan Gayatri Priya, Abhishek Ojha, Mayur K Kajla, Anand Raj, Raman Rajagopal. Host plant induced variation in gut bacteria of Helicoverpa armigera. PloS one. 2012; 7(1):e30768. doi: 10.1371/journal.pone.0030768. [PMID: 22292034]
Marc Thier, Bernhard Münst, Stephanie Mielke, Frank Edenhofer. Cellular reprogramming employing recombinant sox2 protein. Stem cells international. 2012; 2012(?):549846. doi: 10.1155/2012/549846. [PMID: 22693519]
Zhaojing Hao, Li Zheng, Lan Kluwe, Weida Huang. Ferritin light chain and squamous cell carcinoma antigen 1 are coreceptors for cellular attachment and entry of hepatitis B virus. International journal of nanomedicine. 2012; 7(?):827-34. doi: 10.2147/ijn.s27803. [PMID: 22359459]
Nidhi Sofat, Saralili Dipa Robertson, Robin Wait. Fibronectin III 13-14 domains induce joint damage via Toll-like receptor 4 activation and synergize with interleukin-1 and tumour necrosis factor. Journal of innate immunity. 2012; 4(1):69-79. doi: 10.1159/000329632. [PMID: 21997473]
Cuiyue Liang, Lili Sun, Zhufang Yao, Hong Liao, Jiang Tian. Comparative analysis of PvPAP gene family and their functions in response to phosphorus deficiency in common bean. PloS one. 2012; 7(5):e38106. doi: 10.1371/journal.pone.0038106. [PMID: 22662274]
Guennaëlle Dieppois, Véréna Ducret, Olivier Caille, Karl Perron. The transcriptional regulator CzcR modulates antibiotic resistance and quorum sensing in Pseudomonas aeruginosa. PloS one. 2012; 7(5):e38148. doi: 10.1371/journal.pone.0038148. [PMID: 22666466]
Julien Verove, Cédric Bernarde, Yu-Sing Tammy Bohn, François Boulay, Marie-Josèphe Rabiet, Ina Attree, François Cretin. Injection of Pseudomonas aeruginosa Exo toxins into host cells can be modulated by host factors at the level of translocon assembly and/or activity. PloS one. 2012; 7(1):e30488. doi: 10.1371/journal.pone.0030488. [PMID: 22299042]
Jun Yang, Hui-Ping Bi, Wei-Juan Fan, Min Zhang, Hong-Xia Wang, Peng Zhang. Efficient embryogenic suspension culturing and rapid transformation of a range of elite genotypes of sweet potato (Ipomoea batatas [L.] Lam.). Plant science : an international journal of experimental plant biology. 2011 Dec; 181(6):701-11. doi: 10.1016/j.plantsci.2011.01.005. [PMID: 21958713]
Georgina Fabro, Jens Steinbrenner, Mary Coates, Naveed Ishaque, Laura Baxter, David J Studholme, Evelyn Körner, Rebecca L Allen, Sophie J M Piquerez, Alejandra Rougon-Cardoso, David Greenshields, Rita Lei, Jorge L Badel, Marie-Cecile Caillaud, Kee-Hoon Sohn, Guido Van den Ackerveken, Jane E Parker, Jim Beynon, Jonathan D G Jones. Multiple candidate effectors from the oomycete pathogen Hyaloperonospora arabidopsidis suppress host plant immunity. PLoS pathogens. 2011 Nov; 7(11):e1002348. doi: 10.1371/journal.ppat.1002348. [PMID: 22072967]
J Nathan Henderson, Agnieszka M Kuriata, Raimund Fromme, Michael E Salvucci, Rebekka M Wachter. Atomic resolution x-ray structure of the substrate recognition domain of higher plant ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase. The Journal of biological chemistry. 2011 Oct; 286(41):35683-35688. doi: 10.1074/jbc.c111.289595. [PMID: 21880724]
Motonori Tomita, Asuka Okutani, Avigdor Beiles, Eviatar Nevo. Genomic, RNA, and ecological divergences of the Revolver transposon-like multi-gene family in Triticeae. BMC evolutionary biology. 2011 Sep; 11(?):269. doi: 10.1186/1471-2148-11-269. [PMID: 21943048]
Jana Goldová, Aleš Ulrych, Kamil Hercík, Pavel Branny. A eukaryotic-type signalling system of Pseudomonas aeruginosa contributes to oxidative stress resistance, intracellular survival and virulence. BMC genomics. 2011 Aug; 12(?):437. doi: 10.1186/1471-2164-12-437. [PMID: 21880152]
Timothy F Murphy, Aimee L Brauer. Expression of urease by Haemophilus influenzae during human respiratory tract infection and role in survival in an acid environment. BMC microbiology. 2011 Aug; 11(?):183. doi: 10.1186/1471-2180-11-183. [PMID: 21843372]
Christopher A Saski, Zhigang Li, Frank A Feltus, Hong Luo. New genomic resources for switchgrass: a BAC library and comparative analysis of homoeologous genomic regions harboring bioenergy traits. BMC genomics. 2011 Jul; 12(?):369. doi: 10.1186/1471-2164-12-369. [PMID: 21767393]
Jennifer Del Giudice, Yvan Cam, Isabelle Damiani, Franck Fung-Chat, Eliane Meilhoc, Claude Bruand, Renaud Brouquisse, Alain Puppo, Alexandre Boscari. Nitric oxide is required for an optimal establishment of the Medicago truncatula-Sinorhizobium meliloti symbiosis. The New phytologist. 2011 Jul; 191(2):405-417. doi: 10.1111/j.1469-8137.2011.03693.x. [PMID: 21457261]
Hiroaki Saika, Akira Oikawa, Fumio Matsuda, Haruko Onodera, Kazuki Saito, Seiichi Toki. Application of gene targeting to designed mutation breeding of high-tryptophan rice. Plant physiology. 2011 Jul; 156(3):1269-77. doi: 10.1104/pp.111.175778. [PMID: 21543727]
Choonghee Lee, Hyung-Hwan Kim, Kyung Mi Choi, Kyung Won Chung, Yien Kyoung Choi, Mi Jung Jang, Tong-Soo Kim, Nam-Jun Chung, Ho-Gun Rhie, Ho-Sa Lee, Youngjoo Sohn, Hyuck Kim, Sung-Jae Lee, Hyeong-Woo Lee. Murine immune responses to a Plasmodium vivax-derived chimeric recombinant protein expressed in Brassica napus. Malaria journal. 2011 Apr; 10(?):106. doi: 10.1186/1475-2875-10-106. [PMID: 21529346]
Shanping He, Guihong Tan, Qian Liu, Kuowei Huang, Jiao Ren, Xu Zhang, Xiangchun Yu, Ping Huang, Chengcai An. The LSD1-interacting protein GILP is a LITAF domain protein that negatively regulates hypersensitive cell death in Arabidopsis. PloS one. 2011 Apr; 6(4):e18750. doi: 10.1371/journal.pone.0018750. [PMID: 21526181]
Christian Clepet. RNA captor: a tool for RNA characterization. PloS one. 2011 Apr; 6(4):e18445. doi: 10.1371/journal.pone.0018445. [PMID: 21533245]
Maidul Hossain, Asma Yasmeen Khan, Gopinatha Suresh Kumar. Interaction of the anticancer plant alkaloid sanguinarine with bovine serum albumin. PloS one. 2011 Apr; 6(4):e18333. doi: 10.1371/journal.pone.0018333. [PMID: 21494677]
Ka Yu Siu, Mei Kuen Yu, Xinggang Wu, Min Zong, Michael G Roth, Hsiao Chang Chan, Sidney Yu. The non-catalytic carboxyl-terminal domain of ARFGAP1 regulates actin cytoskeleton reorganization by antagonizing the activation of Rac1. PloS one. 2011 Apr; 6(4):e18458. doi: 10.1371/journal.pone.0018458. [PMID: 21483700]
Susan E Ivie, Christine M Fennessey, Jinsong Sheng, Donald H Rubin, Mark S McClain. Gene-trap mutagenesis identifies mammalian genes contributing to intoxication by Clostridium perfringens ε-toxin. PloS one. 2011 Mar; 6(3):e17787. doi: 10.1371/journal.pone.0017787. [PMID: 21412435]
Paola A Cappelletti, Rafael Freitas dos Santos, Alexandre M do Amaral, Rafael Augusto Homem, Thaís dos Santos Souza, Marcos A Machado, Chuck S Farah. Structure-function analysis of the HrpB2-HrcU interaction in the Xanthomonas citri type III secretion system. PloS one. 2011 Mar; 6(3):e17614. doi: 10.1371/journal.pone.0017614. [PMID: 21408079]
Ourania I Pavli, Georgia I Kelaidi, Anastasia P Tampakaki, George N Skaracis. The hrpZ gene of Pseudomonas syringae pv. phaseolicola enhances resistance to rhizomania disease in transgenic Nicotiana benthamiana and sugar beet. PloS one. 2011 Mar; 6(3):e17306. doi: 10.1371/journal.pone.0017306. [PMID: 21394206]
Mandeep S Jassal, Gueno G Nedeltchev, Jonathan Osborne, William R Bishai. A modified scoring system to describe gross pathology in the rabbit model of tuberculosis. BMC microbiology. 2011 Mar; 11(?):49. doi: 10.1186/1471-2180-11-49. [PMID: 21375756]
Cheng-Yuan Kao, Ferdinand C O Los, Danielle L Huffman, Shinichiro Wachi, Nicole Kloft, Matthias Husmann, Valbona Karabrahimi, Jean-Louis Schwartz, Audrey Bellier, Christine Ha, Youn Sagong, Hui Fan, Partho Ghosh, Mindy Hsieh, Chih-Shen Hsu, Li Chen, Raffi V Aroian. Global functional analyses of cellular responses to pore-forming toxins. PLoS pathogens. 2011 Mar; 7(3):e1001314. doi: 10.1371/journal.ppat.1001314. [PMID: 21408619]
Nicola Ilk, Christian-Thomas Schumi, Barbara Bohle, Eva Maria Egelseer, Uwe B Sleytr. Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive Bacillus subtilis 1012 for the potential application as vaccines for immunotherapy of atopic allergy. Microbial cell factories. 2011 Feb; 10(?):6. doi: 10.1186/1475-2859-10-6. [PMID: 21310062]
Liang Yang, Lin Chen, Lixin Shen, Michael Surette, Kangmin Duan. Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence. Journal of microbiology (Seoul, Korea). 2011 Feb; 49(1):107-14. doi: 10.1007/s12275-011-0186-2. [PMID: 21369987]
Xiaoguang Liu, Jinli Jia, Roman Popat, Catherine A Ortori, Jun Li, Stephen P Diggle, Kexiang Gao, Miguel Cámara. Characterisation of two quorum sensing systems in the endophytic Serratia plymuthica strain G3: differential control of motility and biofilm formation according to life-style. BMC microbiology. 2011 Feb; 11(1):26. doi: 10.1186/1471-2180-11-26. [PMID: 21284858]
Upasana Singh, Debadutta Deb, Amanjot Singh, Anil Grover. Glycine-rich RNA binding protein of Oryza sativa inhibits growth of M15 E. coli cells. BMC research notes. 2011 Jan; 4(?):18. doi: 10.1186/1756-0500-4-18. [PMID: 21269485]
Tripty A Hirani, Alejandro Tovar-Méndez, Ján A Miernyk, Douglas D Randall. Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. Enzyme research. 2011 Jan; 2011(?):939068. doi: 10.4061/2011/939068. [PMID: 21318135]
Michael R Weigand, Vinh N Tran, George W Sundin. Growth parameter components of adaptive specificity during experimental evolution of the UVR-inducible mutator Pseudomonas cichorii 302959. PloS one. 2011 Jan; 6(1):e15975. doi: 10.1371/journal.pone.0015975. [PMID: 21264242]
Gwénaël M D J-M Gaussand, Qi Jia, Eric van der Graaff, Gerda E M Lamers, Paul F Fransz, Paul J J Hooykaas, Sylvia de Pater. Programmed Cell Death in the Leaves of the Arabidopsis Spontaneous Necrotic Spots (sns-D) Mutant Correlates with Increased Expression of the Eukaryotic Translation Initiation Factor eIF4B2. Frontiers in plant science. 2011; 2(?):9. doi: 10.3389/fpls.2011.00009. [PMID: 22639576]
Stefan Burén, Cristina Ortega-Villasante, Amaya Blanco-Rivero, Andrea Martínez-Bernardini, Tatiana Shutova, Dmitriy Shevela, Johannes Messinger, Laszlo Bako, Arsenio Villarejo, Göran Samuelsson. Importance of post-translational modifications for functionality of a chloroplast-localized carbonic anhydrase (CAH1) in Arabidopsis thaliana. PloS one. 2011; 6(6):e21021. doi: 10.1371/journal.pone.0021021. [PMID: 21695217]
Hanh H Hoang, Nicholas N Nickerson, Vincent T Lee, Anastasia Kazimirova, Mohamed Chami, Anthony P Pugsley, Stephen Lory. Outer membrane targeting of Pseudomonas aeruginosa proteins shows variable dependence on the components of Bam and Lol machineries. mBio. 2011; 2(6):. doi: 10.1128/mbio.00246-11. [PMID: 22147293]
Letícia Carvalho Neuenschwander, Henrique Bittencourt, Ana Flávia Tibúrcio Ribeiro, Antônio Lúcio Teixeira, Mauro M Teixeira, Jairo Cerqueira Teixeira, Vandack Nobre. Plasma levels of procalcitonin and eight additional inflammatory molecules in febrile neutropenic patients. Clinics (Sao Paulo, Brazil). 2011; 66(10):1699-705. doi: 10.1590/s1807-59322011001000006. [PMID: 22012040]
Wai-Jiao Cai, Jian-Hua Huang, Su-Qin Zhang, Bin Wu, Pankaj Kapahi, Xin-Min Zhang, Zi-Yin Shen. Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans. PloS one. 2011; 6(12):e28835. doi: 10.1371/journal.pone.0028835. [PMID: 22216122]
Angela M Delucia, David A Six, Ruth E Caughlan, Patricia Gee, Ian Hunt, Joseph S Lam, Charles R Dean. Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1. mBio. 2011; 2(4):. doi: 10.1128/mbio.00142-11. [PMID: 21810964]
Zhonghui Zhang, Hao Chen, Xiahe Huang, Ran Xia, Qingzhen Zhao, Jianbin Lai, Kunling Teng, Yin Li, Liming Liang, Quansheng Du, Xueping Zhou, Huishan Guo, Qi Xie. BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis. The Plant cell. 2011 Jan; 23(1):273-88. doi: 10.1105/tpc.110.081695. [PMID: 21245466]
Jennifer M Brulc, Carl J Yeoman, Melissa K Wilson, Margret E Berg Miller, Patricio Jeraldo, Sadanari Jindou, Nigel Goldenfeld, Harry J Flint, Raphael Lamed, Ilya Borovok, Maša Vodovnik, Karen E Nelson, Edward A Bayer, Bryan A White. Cellulosomics, a gene-centric approach to investigating the intraspecific diversity and adaptation of Ruminococcus flavefaciens within the rumen. PloS one. 2011; 6(10):e25329. doi: 10.1371/journal.pone.0025329. [PMID: 22043282]
Peng-Cheng Liu, Jin-Xing Wang, Qi-Sheng Song, Xiao-Fan Zhao. The participation of calponin in the cross talk between 20-hydroxyecdysone and juvenile hormone signaling pathways by phosphorylation variation. PloS one. 2011; 6(5):e19776. doi: 10.1371/journal.pone.0019776. [PMID: 21625546]
Feng Gao, Bang-Jun Zhou, Guo-Ying Li, Pei-Song Jia, Hui Li, Yun-Long Zhao, Pan Zhao, Gui-Xian Xia, Hui-Shan Guo. A glutamic acid-rich protein identified in Verticillium dahliae from an insertional mutagenesis affects microsclerotial formation and pathogenicity. PloS one. 2010 Dec; 5(12):e15319. doi: 10.1371/journal.pone.0015319. [PMID: 21151869]
Teun W J M van Herpen, Katarina Cankar, Marilise Nogueira, Dirk Bosch, Harro J Bouwmeester, Jules Beekwilder. Nicotiana benthamiana as a production platform for artemisinin precursors. PloS one. 2010 Dec; 5(12):e14222. doi: 10.1371/journal.pone.0014222. [PMID: 21151979]
Hiroaki Saika, Seiichi Toki. Mature seed-derived callus of the model indica rice variety Kasalath is highly competent in Agrobacterium-mediated transformation. Plant cell reports. 2010 Dec; 29(12):1351-64. doi: 10.1007/s00299-010-0921-x. [PMID: 20853107]
Monika Janczarek, Jolanta Kutkowska, Tomasz Piersiak, Anna Skorupska. Rhizobium leguminosarum bv. trifolii rosR is required for interaction with clover, biofilm formation and adaptation to the environment. BMC microbiology. 2010 Nov; 10(?):284. doi: 10.1186/1471-2180-10-284. [PMID: 21070666]
Feng-Fa He, Tian Tian, Gui-Xue Wang, Qian Tang, Jian-Ji Zhang. [Effects of different factors on transformed hairy root in Gynostemm apentaphyllum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Nov; 33(11):1675-7. doi: ". [PMID: 21434425]
Diane M Martin, Sébastien Aubourg, Marina B Schouwey, Laurent Daviet, Michel Schalk, Omid Toub, Steven T Lund, Jörg Bohlmann. Functional annotation, genome organization and phylogeny of the grapevine (Vitis vinifera) terpene synthase gene family based on genome assembly, FLcDNA cloning, and enzyme assays. BMC plant biology. 2010 Oct; 10(?):226. doi: 10.1186/1471-2229-10-226. [PMID: 20964856]
Takeo Shimizu, Takuto Nakano, Daisuke Takamizawa, Yoshitake Desaki, Naoko Ishii-Minami, Yoko Nishizawa, Eiichi Minami, Kazunori Okada, Hisakazu Yamane, Hanae Kaku, Naoto Shibuya. Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice. The Plant journal : for cell and molecular biology. 2010 Oct; 64(2):204-14. doi: 10.1111/j.1365-313x.2010.04324.x. [PMID: 21070404]
Bargavi Thyagarajan, Adam G Blaszczak, Katherine J Chandler, Jennifer L Watts, W Evan Johnson, Barbara J Graves. ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. PLoS genetics. 2010 Sep; 6(9):e1001125. doi: 10.1371/journal.pgen.1001125. [PMID: 20862312]
Watcharee Saisongkorh, Catherine Robert, Bernard La Scola, Didier Raoult, Jean-Marc Rolain. Evidence of transfer by conjugation of type IV secretion system genes between Bartonella species and Rhizobium radiobacter in amoeba. PloS one. 2010 Sep; 5(9):e12666. doi: 10.1371/journal.pone.0012666. [PMID: 20856925]
Ralph Lisson, Jan Hellert, Malte Ringleb, Fabian Machens, Josef Kraus, Reinhard Hehl. Alternative splicing of the maize Ac transposase transcript in transgenic sugar beet (Beta vulgaris L.). Plant molecular biology. 2010 Sep; 74(1-2):19-32. doi: 10.1007/s11103-010-9651-2. [PMID: 20512402]
Allen Kovach, Jill L Wegrzyn, Genis Parra, Carson Holt, George E Bruening, Carol A Loopstra, James Hartigan, Mark Yandell, Charles H Langley, Ian Korf, David B Neale. The Pinus taeda genome is characterized by diverse and highly diverged repetitive sequences. BMC genomics. 2010 Jul; 11(?):420. doi: 10.1186/1471-2164-11-420. [PMID: 20609256]
Gregory S Maloney, Andrej Kochevenko, Denise M Tieman, Takayuki Tohge, Uri Krieger, Dani Zamir, Mark G Taylor, Alisdair R Fernie, Harry J Klee. Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato. Plant physiology. 2010 Jul; 153(3):925-36. doi: 10.1104/pp.110.154922. [PMID: 20435740]
Akiko Kubo, Christophe Colleoni, Jason R Dinges, Qiaohui Lin, Ryan R Lappe, Joshua G Rivenbark, Alexander J Meyer, Steven G Ball, Martha G James, Tracie A Hennen-Bierwagen, Alan M Myers. Functions of heteromeric and homomeric isoamylase-type starch-debranching enzymes in developing maize endosperm. Plant physiology. 2010 Jul; 153(3):956-69. doi: 10.1104/pp.110.155259. [PMID: 20448101]
Francisca C Reyes, Beimeng Sun, Hena Guo, Darren Fred Gruis, Marisa S Otegui. Agrobacterium tumefaciens-mediated transformation of maize endosperm as a tool to study endosperm cell biology. Plant physiology. 2010 Jun; 153(2):624-31. doi: 10.1104/pp.110.154930. [PMID: 20357137]
Y He, H D Jones, S Chen, X M Chen, D W Wang, K X Li, D S Wang, L Q Xia. Agrobacterium-mediated transformation of durum wheat (Triticum turgidum L. var. durum cv Stewart) with improved efficiency. Journal of experimental botany. 2010 Jun; 61(6):1567-81. doi: 10.1093/jxb/erq035. [PMID: 20202997]
Giordano Rampioni, Christian Pustelny, Matthew P Fletcher, Victoria J Wright, Mary Bruce, Kendra P Rumbaugh, Stephan Heeb, Miguel Cámara, Paul Williams. Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts. Environmental microbiology. 2010 Jun; 12(6):1659-73. doi: 10.1111/j.1462-2920.2010.02214.x. [PMID: 20406282]
Melanie L Hand, Noel O I Cogan, Timothy I Sawbridge, German C Spangenberg, John W Forster. Comparison of homoeolocus organisation in paired BAC clones from white clover (Trifolium repens L.) and microcolinearity with model legume species. BMC plant biology. 2010 May; 10(?):94. doi: 10.1186/1471-2229-10-94. [PMID: 20492736]
Fang Huang, Marcelo Kemel Zago, Lindy Abas, Arnoud van Marion, Carlos Samuel Galván-Ampudia, Remko Offringa. Phosphorylation of conserved PIN motifs directs Arabidopsis PIN1 polarity and auxin transport. The Plant cell. 2010 Apr; 22(4):1129-42. doi: 10.1105/tpc.109.072678. [PMID: 20407025]
Daniel R Gallie. Regulated ethylene insensitivity through the inducible expression of the Arabidopsis etr1-1 mutant ethylene receptor in tomato. Plant physiology. 2010 Apr; 152(4):1928-39. doi: 10.1104/pp.109.151688. [PMID: 20181754]
Takayuki Teramoto, Laura A Sternick, Eriko Kage-Nakadai, Shirine Sajjadi, Jakub Siembida, Shohei Mitani, Kouichi Iwasaki, Eric J Lambie. Magnesium excretion in C. elegans requires the activity of the GTL-2 TRPM channel. PloS one. 2010 Mar; 5(3):e9589. doi: 10.1371/journal.pone.0009589. [PMID: 20221407]
Christine A Newell, Naomi J Brown, Zheng Liu, Alexander Pflug, Udo Gowik, Peter Westhoff, Julian M Hibberd. Agrobacterium tumefaciens-mediated transformation of Cleome gynandra L., a C(4) dicotyledon that is closely related to Arabidopsis thaliana. Journal of experimental botany. 2010 Mar; 61(5):1311-9. doi: 10.1093/jxb/erq009. [PMID: 20150516]
Hou-Sung Jung, Krishna K Niyogi. Mutations in Arabidopsis YCF20-like genes affect thermal dissipation of excess absorbed light energy. Planta. 2010 Mar; 231(4):923-37. doi: 10.1007/s00425-010-1098-9. [PMID: 20087601]
Heiko Oltmanns, Bronwyn Frame, Lan-Ying Lee, Susan Johnson, Bo Li, Kan Wang, Stanton B Gelvin. Generation of backbone-free, low transgene copy plants by launching T-DNA from the Agrobacterium chromosome. Plant physiology. 2010 Mar; 152(3):1158-66. doi: 10.1104/pp.109.148585. [PMID: 20023148]
Alonso G Pérez-Donoso, Qiang Sun, M Caroline Roper, L Carl Greve, Bruce Kirkpatrick, John M Labavitch. Cell wall-degrading enzymes enlarge the pore size of intervessel pit membranes in healthy and Xylella fastidiosa-infected grapevines. Plant physiology. 2010 Mar; 152(3):1748-59. doi: 10.1104/pp.109.148791. [PMID: 20107028]
Takayuki Sasaki, Izumi C Mori, Takuya Furuichi, Shintaro Munemasa, Kiminori Toyooka, Ken Matsuoka, Yoshiyuki Murata, Yoko Yamamoto. Closing plant stomata requires a homolog of an aluminum-activated malate transporter. Plant & cell physiology. 2010 Mar; 51(3):354-65. doi: 10.1093/pcp/pcq016. [PMID: 20154005]
Young-Beob Yu, Laura Dosanjh, Lixing Lao, Ming Tan, Bum Sang Shim, Yuan Luo. Cinnamomum cassia bark in two herbal formulas increases life span in Caenorhabditis elegans via insulin signaling and stress response pathways. PloS one. 2010 Feb; 5(2):e9339. doi: 10.1371/journal.pone.0009339. [PMID: 20179756]
Seema Singh, Susanna A Braus-Stromeyer, Christian Timpner, Van Tuan Tran, Gertrud Lohaus, Michael Reusche, Jessica Knüfer, Thomas Teichmann, Andreas von Tiedemann, Gerhard H Braus. Silencing of Vlaro2 for chorismate synthase revealed that the phytopathogen Verticillium longisporum induces the cross-pathway control in the xylem. Applied microbiology and biotechnology. 2010 Feb; 85(6):1961-76. doi: 10.1007/s00253-009-2269-0. [PMID: 19826808]
Elzbieta Justyńska, Anna Powarzyńska, Jolanta Długaszewska. [Antimicrobial susceptibility of microorganisms isolated from urine of pediatric ward patients]. Medycyna doswiadczalna i mikrobiologia. 2010; 62(3):231-6. doi: NULL. [PMID: 21114015]
Shinong Long, Elaine Phan, Michel C Vellard. The expression of soluble and active recombinant Haemophilus influenzae IgA1 protease in E. coli. Journal of biomedicine & biotechnology. 2010; 2010(?):253983. doi: 10.1155/2010/253983. [PMID: 21151648]
Hidenobu Uchida, Hirofumi Yamashita, Toyoaki Anai, Toshiya Muranaka, Kanji Ohyama. Agrobacterium-mediated transformation of Euphorbia tirucalli callus. Bioscience, biotechnology, and biochemistry. 2010; 74(4):851-3. doi: 10.1271/bbb.90783. [PMID: 20445322]
Lan-Xin Shi, Steven M Theg. A stromal heat shock protein 70 system functions in protein import into chloroplasts in the moss Physcomitrella patens. The Plant cell. 2010 Jan; 22(1):205-20. doi: 10.1105/tpc.109.071464. [PMID: 20061551]
Tomasz Bogiel, Agnieszka Mikucka, Tomasz Skalski, Eugenia Gospodarek. [Occurrence and susceptibility to antibiotics of carbapenem-resistant Pseudomonas aeruginosa strains between 1998 and 2009]. Medycyna doswiadczalna i mikrobiologia. 2010; 62(3):221-9. doi: . [PMID: 21114014]
Joseph J Carter, Kelly G Paulson, Greg C Wipf, Danielle Miranda, Margaret M Madeleine, Lisa G Johnson, Bianca D Lemos, Sherry Lee, Ashley H Warcola, Jayasri G Iyer, Paul Nghiem, Denise A Galloway. Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma. Journal of the National Cancer Institute. 2009 Nov; 101(21):1510-22. doi: 10.1093/jnci/djp332. [PMID: 19776382]
Christina Ramel, Micha Tobler, Martin Meyer, Laurent Bigler, Marc-Olivier Ebert, Barbara Schellenberg, Robert Dudler. Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate. BMC biochemistry. 2009 Oct; 10(?):26. doi: 10.1186/1471-2091-10-26. [PMID: 19863801]
Rebecca M Green, Fabienne Gally, Jonathon G Keeney, Scott Alper, Bifeng Gao, Min Han, Richard J Martin, Andrew R Weinberger, Stephanie R Case, Maisha N Minor, Hong Wei Chu. Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. PloS one. 2009 Aug; 4(8):e6860. doi: 10.1371/journal.pone.0006860. [PMID: 19718433]
Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance. Journal of medicinal chemistry. 2009 Aug; 52(15):4844-52. doi: 10.1021/jm900403j. [PMID: 19445515]
Steven Garvis, Antje Munder, Geneviève Ball, Sophie de Bentzmann, Lutz Wiehlmann, Jonathan J Ewbank, Burkhard Tümmler, Alain Filloux. Caenorhabditis elegans semi-automated liquid screen reveals a specialized role for the chemotaxis gene cheB2 in Pseudomonas aeruginosa virulence. PLoS pathogens. 2009 Aug; 5(8):e1000540. doi: 10.1371/journal.ppat.1000540. [PMID: 19662168]
Matthew W Blair, Monica Muñoz Torres, Martha C Giraldo, Fabio Pedraza. Development and diversity of Andean-derived, gene-based microsatellites for common bean (Phaseolus vulgaris L.). BMC plant biology. 2009 Jul; 9(?):100. doi: 10.1186/1471-2229-9-100. [PMID: 19646251]
Jens C Göpfert, Gillian Macnevin, Dae-Kyun Ro, Otmar Spring. Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. BMC plant biology. 2009 Jul; 9(?):86. doi: 10.1186/1471-2229-9-86. [PMID: 19580670]