2-Oxazolidinone (BioDeep_00000006286)
Secondary id: BioDeep_00001868392
human metabolite blood metabolite
代谢物信息卡片
1,3 Oxazolidine 2 one
化学式: C3H5NO2 (87.032027)
中文名称: 2-噁唑烷酮
谱图信息:
最多检出来源 Homo sapiens(blood) 62.26%
分子结构信息
SMILES: C1COC(=O)N1
InChI: InChI=1S/C3H5NO2/c5-3-4-1-2-6-3/h1-2H2,(H,4,5)
描述信息
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones
同义名列表
数据库引用编号
16 个数据库交叉引用编号
- ChEBI: CHEBI:1237
- KEGG: C93484
- KEGG: C06695
- PubChem: 73949
- HMDB: HMDB0245282
- Metlin: METLIN66496
- ChEMBL: CHEMBL1867161
- Wikipedia: 2-Oxazolidone
- MeSH: Oxazolidinones
- chemspider: 66579
- CAS: 51667-26-6
- CAS: 497-25-6
- PMhub: MS000019308
- PubChem: 8920
- 3DMET: B02093
- NIKKAJI: J36.850D
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Masahiro Toyokawa, Noboru Ohana, Daiki Tanno, Minako Imai, Yukiko Takano, Kazutaka Ohashi, Tomonari Yamashita, Kyoichi Saito, Hiroki Takahashi, Hiroki Shimura. In vitro activity of tedizolid against 43 species of Nocardia species.
Scientific reports.
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ACS infectious diseases.
2022 10; 8(10):2187-2197. doi:
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Fitoterapia.
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Microbial drug resistance (Larchmont, N.Y.).
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The Journal of antimicrobial chemotherapy.
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Surgical infections.
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Food chemistry.
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Molecules (Basel, Switzerland).
2022 Feb; 27(3):. doi:
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Pharmaceutical nanotechnology.
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Biological & pharmaceutical bulletin.
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Medicine.
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2021 Nov; 51(11):1292-1302. doi:
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Antimicrobial agents and chemotherapy.
2021 10; 65(11):e0040921. doi:
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Nature communications.
2021 09; 12(1):5640. doi:
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Journal of medicinal chemistry.
2021 09; 64(18):13215-13258. doi:
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2021 09; 26(?):308-316. doi:
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Journal of chromatography. A.
2021 Aug; 1651(?):462276. doi:
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The Journal of antimicrobial chemotherapy.
2021 08; 76(9):2479-2481. doi:
10.1093/jac/dkab162. [PMID: 34008028] - Hanjing Chen, Weili Chen, Hui Li, Hongrong Xu, Fei Yuan, Lei Sheng, Chao Liu, Pingping Lin, Mengjie Yang, Xuening Li, Yang Liu, Brittany Marie Walker, Ferdous Gheyas, Marian Iwamoto, S Aubrey Stoch, Rajesh Krishna. Pharmacokinetics, Safety and Tolerability of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein (CETP) Inhibitor, After Single and Multiple Doses in Healthy Chinese Subjects.
Advances in therapy.
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Pest management science.
2021 May; 77(5):2454-2461. doi:
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Clinical biochemistry.
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2021 Apr; 105(?):688-694. doi:
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Journal of medicinal chemistry.
2021 03; 64(6):3234-3248. doi:
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Circulation.
2021 03; 143(9):921-934. doi:
10.1161/circulationaha.120.048568. [PMID: 33228395] - Ryota Tanaka, Makoto Kai, Koji Goto, Yoshifumi Ohchi, Norihisa Yasuda, Ryosuke Tatsuta, Takaaki Kitano, Hiroki Itoh. High-throughput and wide-range simultaneous determination of linezolid, daptomycin and tedizolid in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry.
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2021 Feb; 194(?):113764. doi:
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Advances in therapy.
2021 02; 38(2):1024-1034. doi:
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2020 12; 9(24):e018136. doi:
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Antimicrobial agents and chemotherapy.
2020 10; 64(11):. doi:
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Cell biochemistry and function.
2020 Oct; 38(7):880-885. doi:
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Journal of clinical pharmacology.
2020 10; 60(10):1314-1323. doi:
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Medical hypotheses.
2020 Aug; 141(?):109740. doi:
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Biomedical chromatography : BMC.
2020 Jun; 34(6):e4820. doi:
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2020 Jun; 1146(?):122018. doi:
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Antimicrobial agents and chemotherapy.
2020 05; 64(6):. doi:
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Journal of ethnopharmacology.
2020 Apr; 251(?):112550. doi:
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Scientific reports.
2020 02; 10(1):3747. doi:
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Frontiers in public health.
2020; 8(?):518. doi:
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International journal of biological macromolecules.
2020 Jan; 142(?):52-62. doi:
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Current molecular medicine.
2020; 20(8):643-652. doi:
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Bioanalysis.
2020 Jan; 12(1):23-34. doi:
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International journal of nanomedicine.
2020; 15(?):8553-8568. doi:
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Xenobiotica; the fate of foreign compounds in biological systems.
2019 Dec; 49(12):1434-1446. doi:
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Pharmacology research & perspectives.
2019 12; 7(6):e00543. doi:
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Journal of pharmacokinetics and pharmacodynamics.
2019 12; 46(6):531-541. doi:
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Journal of global antimicrobial resistance.
2019 12; 19(?):333-337. doi:
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Scientific reports.
2019 11; 9(1):16183. doi:
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Journal of chemotherapy (Florence, Italy).
2019 Oct; 31(6):313-319. doi:
10.1080/1120009x.2019.1623968. [PMID: 31215343] - Liqiang Gu, Munong Ma, Yuan Zhang, Lijiang Zhang, Sheng Zhang, Mincong Huang, Majuan Zhang, Yanfei Xin, Gaoli Zheng, Suhong Chen. Comparative pharmacokinetics of tedizolid in rat plasma and cerebrospinal fluid.
Regulatory toxicology and pharmacology : RTP.
2019 Oct; 107(?):104420. doi:
10.1016/j.yrtph.2019.104420. [PMID: 31295511] - Jinhang Li, Yanhong Shi, Yan Xu, Li Yang, Zhengtao Wang, Han Han, Rui Wang. Metabolic profiles and pharmacokinetics of goitrin in rats through liquid chromatography combined with electrospray ionization-tandem mass spectrometry.
Biomedical chromatography : BMC.
2019 Oct; 33(10):e4606. doi:
10.1002/bmc.4606. [PMID: 31132308] - Sneha M Dixit, Mohd Ahsan, Sanjib Senapati. Steering the Lipid Transfer To Unravel the Mechanism of Cholesteryl Ester Transfer Protein Inhibition.
Biochemistry.
2019 09; 58(36):3789-3801. doi:
10.1021/acs.biochem.9b00301. [PMID: 31418269] - Jinhu Huang, Mengli Wang, Yi Gao, Li Chen, Liping Wang. Emergence of plasmid-mediated oxazolidinone resistance gene poxtA from CC17 Enterococcus faecium of pig origin.
The Journal of antimicrobial chemotherapy.
2019 09; 74(9):2524-2530. doi:
10.1093/jac/dkz250. [PMID: 31236590] - Mwila Mulubwa, Pierre Mugabo. Steady-state population pharmacokinetics of terizidone and its metabolite cycloserine in patients with drug-resistant tuberculosis.
British journal of clinical pharmacology.
2019 09; 85(9):1946-1956. doi:
10.1111/bcp.13975. [PMID: 31046167] - Vimal Maurya, Pranesh Kumar, Sreemoyee Chakraborti, Ashok K Singh, Archana S Bhadauria, Umesh Kumar, Dinesh Kumar, Arnab Pramanik, Biswajit Saha, Venkatesh Kumar R, Sunil Babu Gosipatala, Bolay Bhattachariya, Biswanath Maity, Sudipta Saha. Zolmitriptan attenuates hepatocellular carcinoma via activation of caspase mediated apoptosis.
Chemico-biological interactions.
2019 Aug; 308(?):120-129. doi:
10.1016/j.cbi.2019.05.033. [PMID: 31129132] - Dandara Fidélis Escoto, Mateus Cristofary Gayer, Matheus Chimelo Bianchini, Geovana da Cruz Pereira, Rafael Roehrs, Elton L G Denardin. Use of Pistia stratiotes for phytoremediation of water resources contaminated by clomazone.
Chemosphere.
2019 Jul; 227(?):299-304. doi:
10.1016/j.chemosphere.2019.04.013. [PMID: 30999171] - Junzhen Wu, Hailan Wu, Yu Wang, Yuancheng Chen, Beining Guo, Guoying Cao, Xiaojie Wu, Jicheng Yu, Jufang Wu, Demei Zhu, Yan Guo, Hong Yuan, Fupin Hu, Jing Zhang. Tolerability and Pharmacokinetics of Contezolid at Therapeutic and Supratherapeutic Doses in Healthy Chinese Subjects, and Assessment of Contezolid Dosing Regimens Based on Pharmacokinetic/Pharmacodynamic Analysis.
Clinical therapeutics.
2019 06; 41(6):1164-1174.e4. doi:
10.1016/j.clinthera.2019.04.025. [PMID: 31126694] - Feng Guo, Satoshi Iwakami, Takuya Yamaguchi, Akira Uchino, Yukari Sunohara, Hiroshi Matsumoto. Role of CYP81A cytochrome P450s in clomazone metabolism in Echinochloa phyllopogon.
Plant science : an international journal of experimental plant biology.
2019 Jun; 283(?):321-328. doi:
10.1016/j.plantsci.2019.02.010. [PMID: 31128703] - Seok Hyeon Na, Dong Chan Moon, Myeong-Ja Choi, Sun-Joo Oh, Dae-Young Jung, Hee Young Kang, Bang-Hun Hyun, Suk-Kyung Lim. Detection of oxazolidinone and phenicol resistant enterococcal isolates from duck feces and carcasses.
International journal of food microbiology.
2019 Mar; 293(?):53-59. doi:
10.1016/j.ijfoodmicro.2019.01.002. [PMID: 30640000] - Douglas G Johns, Lauretta LeVoci, Mihajlo Krsmanovic, Min Lu, Georgy Hartmann, Suoyu Xu, Sheng-Ping Wang, Ying Chen, Thomas Bateman, Robert O Blaustein. Characterization of Anacetrapib Distribution into the Lipid Droplet of Adipose Tissue in Mice and Human Cultured Adipocytes.
Drug metabolism and disposition: the biological fate of chemicals.
2019 03; 47(3):227-233. doi:
10.1124/dmd.118.084525. [PMID: 30567880] - Kaoru Kobayashi, Yoshikazu Abe, Hiroshi Harada, Emiko Oota, Takuro Endo, Hiroo Takeda. Non-clinical pharmacokinetic profiles of rovatirelin, an orally available thyrotropin-releasing hormone analogue.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Jan; 49(1):106-119. doi:
10.1080/00498254.2017.1423130. [PMID: 29300135] - Yong-Soon Cho, Hyeong-Seok Lim, Sungpil Han, Seok Kyu Yoon, Hyungsub Kim, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Single-dose Intravenous Safety, Tolerability, and Pharmacokinetics and Absolute Bioavailability of LCB01-0371.
Clinical therapeutics.
2019 01; 41(1):92-106. doi:
10.1016/j.clinthera.2018.11.009. [PMID: 30559004] - John O'Donnell, Ken Lawrence, Karthick Vishwanathan, Vinayak Hosagrahara, John P Mueller. Single-Dose Pharmacokinetics, Excretion, and Metabolism of Zoliflodacin, a Novel Spiropyrimidinetrione Antibiotic, in Healthy Volunteers.
Antimicrobial agents and chemotherapy.
2019 01; 63(1):. doi:
10.1128/aac.01808-18. [PMID: 30373802] - Pengqiang Du, Xiaohu Wu, Jun Xu, Fengshou Dong, Xingang Liu, Ying Zhang, Yongquan Zheng. Clomazone influence soil microbial community and soil nitrogen cycling.
The Science of the total environment.
2018 Dec; 644(?):475-485. doi:
10.1016/j.scitotenv.2018.06.214. [PMID: 29990898] - Yong-Soon Cho, Hyeong-Seok Lim, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Multiple-dose Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral LCB01-0371 in Healthy Male Volunteers.
Clinical therapeutics.
2018 12; 40(12):2050-2064. doi:
10.1016/j.clinthera.2018.10.007. [PMID: 30420289] - Lin Zhu, Thao Luu, Christopher H Emfinger, Bryan A Parks, Jeanne Shi, Elijah Trefts, Fenghua Zeng, Zsuzsanna Kuklenyik, Raymond C Harris, David H Wasserman, Sergio Fazio, John M Stafford. CETP Inhibition Improves HDL Function but Leads to Fatty Liver and Insulin Resistance in CETP-Expressing Transgenic Mice on a High-Fat Diet.
Diabetes.
2018 12; 67(12):2494-2506. doi:
10.2337/db18-0474. [PMID: 30213825] - Rajesh Krishna, Ferdous Gheyas, Christy Corr, Josee Cote, Yang Liu, John Wagner, David E Gutstein. Pharmacokinetics and Pharmacodynamics of Anacetrapib in Black and White Healthy Subjects.
Journal of clinical pharmacology.
2018 12; 58(12):1578-1585. doi:
10.1002/jcph.1287. [PMID: 30029292] - Mwila Mulubwa, Pierre Mugabo. Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.
Biomedical chromatography : BMC.
2018 Nov; 32(11):e4325. doi:
10.1002/bmc.4325. [PMID: 29947117] - Yamato Sano, Tadahaya Mizuno, Tatsuki Mochizuki, Yasuo Uchida, Mina Umetsu, Tetsuya Terasaki, Hiroyuki Kusuhara. Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier.
Drug metabolism and disposition: the biological fate of chemicals.
2018 11; 46(11):1767-1775. doi:
10.1124/dmd.118.081877. [PMID: 30154106] - Philip J Barter, Blake J Cochran, Kerry-Anne Rye. CETP inhibition, statins and diabetes.
Atherosclerosis.
2018 11; 278(?):143-146. doi:
10.1016/j.atherosclerosis.2018.09.033. [PMID: 30278356] - Niels Agerbirk, Annemarie Matthes, Pernille Ø Erthmann, Luisa Ugolini, Susanna Cinti, Eleni Lazaridi, Jean-Marc Nuzillard, Caroline Müller, Søren Bak, Patrick Rollin, Luca Lazzeri. Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide.
Phytochemistry.
2018 Sep; 153(?):79-93. doi:
10.1016/j.phytochem.2018.05.006. [PMID: 29886160] - Zhiwei Yang, Yang Cao, Dongxiao Hao, Xiaohui Yuan, Lei Zhang, Shengli Zhang. Binding profiles of cholesterol ester transfer protein with current inhibitors: a look at mechanism and drawback.
Journal of biomolecular structure & dynamics.
2018 Aug; 36(10):2567-2580. doi:
10.1080/07391102.2017.1363661. [PMID: 28777919] - Yong-Soon Cho, Hyeong-Seok Lim, Shi-Hyang Lee, Young Lag Cho, Hee-Sook Nam, Kyun-Seop Bae. Pharmacokinetics, Pharmacodynamics, and Tolerability of Single-Dose Oral LCB01-0371, a Novel Oxazolidinone with Broad-Spectrum Activity, in Healthy Volunteers.
Antimicrobial agents and chemotherapy.
2018 07; 62(7):. doi:
10.1128/aac.00451-18. [PMID: 29712654] - Yanhong Shi, Cheng Zheng, Jinhang Li, Li Yang, Zhengtao Wang, Rui Wang. Separation and Quantification of Four Main Chiral Glucosinolates in Radix Isatidis and Its Granules Using High-Performance Liquid Chromatography/Diode Array Detector Coupled with Circular Dichroism Detection.
Molecules (Basel, Switzerland).
2018 May; 23(6):. doi:
10.3390/molecules23061305. [PMID: 29844266] - Yusuke Masuda, Shinji Yamaguchi, Chikako Suzuki, Takahide Aburatani, Yuki Nagano, Ryuki Miyauchi, Eiko Suzuki, Naotoshi Yamamura, Kentaro Nagatomo, Hidetoshi Ishihara, Kazuaki Okuno, Futoshi Nara, Gabriele Matschiner, Ryuji Hashimoto, Tohru Takahashi, Tomohiro Nishizawa. Generation and Characterization of a Novel Small Biologic Alternative to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Antibodies, DS-9001a, Albumin Binding Domain-Fused Anticalin Protein.
The Journal of pharmacology and experimental therapeutics.
2018 05; 365(2):368-378. doi:
10.1124/jpet.117.246652. [PMID: 29463608] - Sheila A Doggrell. Cardiovascular outcomes trial with anacetrapib in subjects with high cardiovascular risk - are major benefits REVEALed?.
Expert opinion on pharmacotherapy.
2018 Apr; 19(6):611-615. doi:
10.1080/14656566.2018.1448061. [PMID: 29498299] - Matthieu Grégoire, Julia Brochard Libois, Denis Waast, Benjamin Gaborit, Marc Dauty, Guillaume Deslandes, Eric Dailly, Sophie Touchais, David Boutoille, Nicolas Grégoire, William Couet. Pharmacokinetics of Tedizolid in an Obese Patient after Bariatric Surgery.
Antimicrobial agents and chemotherapy.
2018 04; 62(4):. doi:
10.1128/aac.02432-17. [PMID: 29378714] - Mekki Bensaci, Shawn Flanagan, Taylor Sandison. Determination of Tedizolid susceptibility interpretive criteria for gram-positive pathogens according to clinical and laboratory standards institute guidelines.
Diagnostic microbiology and infectious disease.
2018 Mar; 90(3):214-220. doi:
10.1016/j.diagmicrobio.2017.10.023. [PMID: 29277464] - L P Zhu, J P Wang, X M Ding, S P Bai, Q F Zeng, Z W Su, Y Xuan, K Y Zhang. The Deposition and Elimination of Glucosinolate Metabolites Derived from Rapeseed Meal in Eggs of Laying Hens.
Journal of agricultural and food chemistry.
2018 Feb; 66(6):1560-1568. doi:
10.1021/acs.jafc.7b05782. [PMID: 29345135] - Rajesh Krishna, Ferdous Gheyas, Yang Liu, Josee Cote, Omar Laterza, Jon L Ruckle, John A Wagner, Andrew E Denker. Pharmacokinetics and Pharmacodynamics of Anacetrapib Following Single Doses in Healthy, Young Japanese and White Male Subjects.
Journal of clinical pharmacology.
2018 02; 58(2):254-262. doi:
10.1002/jcph.1004. [PMID: 28884824] - Xiaojie Wu, Yunfei Li, Jing Zhang, Yingyuan Zhang, Jicheng Yu, Guoying Cao, Yuancheng Chen, Beining Guo, Yaoguo Shi, Jun Huang, Yuran Cao, Xiaofang Liu, Jufang Wu, Mikhail Fedorovich Gordeev, Hong Yuan, Wen Wang. Short-term Safety, Tolerability, and Pharmacokinetics of MRX-I, an Oxazolidinone Antibacterial Agent, in Healthy Chinese Subjects.
Clinical therapeutics.
2018 02; 40(2):322-332.e5. doi:
10.1016/j.clinthera.2017.12.017. [PMID: 29398160] - Alan R Tall, Daniel J Rader. Trials and Tribulations of CETP Inhibitors.
Circulation research.
2018 01; 122(1):106-112. doi:
10.1161/circresaha.117.311978. [PMID: 29018035] - R Court, L Wiesner, A Stewart, N de Vries, J Harding, G Maartens, T Gumbo, H McIlleron. Steady state pharmacokinetics of cycloserine in patients on terizidone for multidrug-resistant tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
2018 01; 22(1):30-33. doi:
10.5588/ijtld.17.0475. [PMID: 29297422] - Sean M Stainton, Marguerite L Monogue, Arlinda Baummer-Carr, Ashley K Shepard, James F Nugent, Joseph L Kuti, David P Nicolau. Comparative Assessment of Tedizolid Pharmacokinetics and Tissue Penetration between Diabetic Patients with Wound Infections and Healthy Volunteers via In Vivo Microdialysis.
Antimicrobial agents and chemotherapy.
2018 01; 62(1):. doi:
10.1128/aac.01880-17. [PMID: 29109162] - Jung Sunwoo, Yu Kyong Kim, Yewon Choi, Kyung-Sang Yu, Heesook Nam, Young Lag Cho, Seonghae Yoon, Jae-Yong Chung. Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic.
Drug design, development and therapy.
2018; 12(?):1707-1714. doi:
10.2147/dddt.s155657. [PMID: 29928114] - Meike Siebers, Thomas Rohr, Marina Ventura, Vadim Schütz, Stephan Thies, Filip Kovacic, Karl-Erich Jaeger, Martin Berg, Peter Dörmann, Margot Schulz. Disruption of microbial community composition and identification of plant growth promoting microorganisms after exposure of soil to rapeseed-derived glucosinolates.
PloS one.
2018; 13(7):e0200160. doi:
10.1371/journal.pone.0200160. [PMID: 29969500] - Ben J Wu, Yue Li, Kwok L Ong, Yidan Sun, Sudichhya Shrestha, Liming Hou, Douglas Johns, Philip J Barter, Kerry-Anne Rye. Reduction of In-Stent Restenosis by Cholesteryl Ester Transfer Protein Inhibition.
Arteriosclerosis, thrombosis, and vascular biology.
2017 12; 37(12):2333-2341. doi:
10.1161/atvbaha.117.310051. [PMID: 29025709] - Liwei He, Fangtian Fan, Xianbang Hou, Hongyan Wu, Juan Wang, Huiqin Xu, Yun Sun. 4(3H)-Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell.
International immunopharmacology.
2017 Nov; 52(?):245-252. doi:
10.1016/j.intimp.2017.09.010. [PMID: 28957692] - R Krishna, F Gheyas, Y Liu, D R Hagen, B Walker, A Chawla, J Cote, R O Blaustein, D E Gutstein. Chronic Administration of Anacetrapib Is Associated With Accumulation in Adipose and Slow Elimination.
Clinical pharmacology and therapeutics.
2017 Nov; 102(5):832-840. doi:
10.1002/cpt.700. [PMID: 28380664] - Luis Masana. Results of the REVEAL study. Why Should we not welcome a new lipid lowering agent?.
Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis.
2017 Nov; 29(6):278-279. doi:
10.1016/j.arteri.2017.10.002. [PMID: 29173491] - Sally E Wenzel, Yulia Y Tyurina, Jinming Zhao, Claudette M St Croix, Haider H Dar, Gaowei Mao, Vladimir A Tyurin, Tamil S Anthonymuthu, Alexandr A Kapralov, Andrew A Amoscato, Karolina Mikulska-Ruminska, Indira H Shrivastava, Elizabeth M Kenny, Qin Yang, Joel C Rosenbaum, Louis J Sparvero, David R Emlet, Xiaoyan Wen, Yoshinori Minami, Feng Qu, Simon C Watkins, Theodore R Holman, Andrew P VanDemark, John A Kellum, Ivet Bahar, Hülya Bayır, Valerian E Kagan. PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.
Cell.
2017 Oct; 171(3):628-641.e26. doi:
10.1016/j.cell.2017.09.044. [PMID: 29053969] - Wangda Zhou, Jianguo Li, Bruce Birmingham, Hongmei Xu, Stefan Lillieborg, Diansong Zhou, Nidal Al-Huniti. Population Pharmacokinetic Analysis of Zolmitriptan and Its Metabolite in Adults and Adolescents to Support Dose Selection in Children With Migraine.
Journal of clinical pharmacology.
2017 10; 57(10):1258-1267. doi:
10.1002/jcph.935. [PMID: 28581633] - Juliane Silberschmidt Freitas, Andreia Arantes Felício, Fabrício Barreto Teresa, Eduardo Alves de Almeida. Combined effects of temperature and clomazone (Gamit®) on oxidative stress responses and B-esterase activity of Physalaemus nattereri (Leiuperidae) and Rhinella schneideri (Bufonidae) tadpoles.
Chemosphere.
2017 Oct; 185(?):548-562. doi:
10.1016/j.chemosphere.2017.07.061. [PMID: 28719874] - Tiffany Thomas, Haihong Zhou, Wahida Karmally, Rajasekhar Ramakrishnan, Stephen Holleran, Yang Liu, Patricia Jumes, John A Wagner, Brian Hubbard, Stephen F Previs, Thomas Roddy, Amy O Johnson-Levonas, David E Gutstein, Santica M Marcovina, Daniel J Rader, Henry N Ginsberg, John S Millar, Gissette Reyes-Soffer. CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects.
Arteriosclerosis, thrombosis, and vascular biology.
2017 09; 37(9):1770-1775. doi:
10.1161/atvbaha.117.309549. [PMID: 28729361] - Harilal Patel, Prakash Patel, Nirav Modi, Shaival Shah, Ashok Ghoghari, Bhavesh Variya, Ritu Laddha, Dipesh Baradia, Nitin Dobaria, Pavak Mehta, Nuggehally R Srinivas. One should avoid retro-orbital pharmacokinetic sample collections for intranasal dosing in rats: Illustration of spurious pharmacokinetics generated for anti-migraine drugs zolmitriptan and eletriptan.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2017 Aug; 106(?):87-93. doi:
10.1016/j.ejps.2017.05.044. [PMID: 28549679]