hopene (BioDeep_00000006106)

Volatile Flavor Compounds

代谢物信息卡片

N-(3alpha,7beta,12alpha-trihydroxy-5beta-cholan-24-oyl)-taurine

化学式: C30H50 (410.39123)
中文名称: 何帕烯
谱图信息: 最多检出来源 Bos taurus(blood) 1.54%

分子结构信息

SMILES: C=C(C)C1CCC2(C)C1CCC1(C)C2CCC2C3(C)CCCC(C)(C)C3CCC21C
InChI: InChI=1S/C30H50/c1-20(2)21-12-17-27(5)22(21)13-18-29(7)24(27)10-11-25-28(6)16-9-15-26(3,4)23(28)14-19-30(25,29)8/h21-25H,1,9-19H2,2-8H3/t21-,22+,23+,24-,25-,27+,28+,29-,30-/m1/s1

描述信息

同义名列表

15 个代谢物同义名

Diploptene; hopene; A-neogammacer-22(29)-ene; Hop-22(29)-ene solution; Hop-22(29)-ene; 22(29)-Hopene; LMST06000001; 04626_FLUKA; 114784-90-6; CHEBI:4648; 1615-91-4; C06310; N-(3alpha,7beta,12alpha-trihydroxy-5beta-cholan-24-oyl)-taurine; Hopene b; Diploptene

数据库引用编号

16 个数据库交叉引用编号

ChEBI: CHEBI:4648
KEGG: C06310
PubChem: 92155
PubChem: 605866
Metlin: METLIN58000
ChEMBL: CHEMBL455613
LipidMAPS: LMPR04000001
MetaCyc: HOP-2229-ENE
CAS: 1615-91-4
PMhub: MS000019079
PubChem: 8546
3DMET: B02006
NIKKAJI: J7.532I
LOTUS: LTS0013192
wikidata: Q14124950
KNApSAcK: 4648

分类词条

代谢反应

3 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(2)

hopanoid biosynthesis (bacteria): SAM + methylcob(III)alamin + tetrahymanol ⟶ 2-methyltetrahymanol + 5'-deoxyadenosine + cob(III)alamin + met
diploterol and cycloartenol biosynthesis: (3S)-2,3-epoxy-2,3-dihydrosqualene ⟶ cycloartenol

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(1)

diploterol biosynthesis: H₂O + squalene ⟶ hopan-22-ol

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

32 个相关的物种来源信息

61542 - Abietinella abietina: 10.1016/S0031-9422(00)97390-4
13818 - Adiantum capillus-veneris:
872336 - Adiantum edgeworthii: 10.1248/CPB.42.45
204586 - Alsophila spinulosa:
29634 - Cheiropleuria bicuspis: 10.1248/CPB.38.2130
29639 - Davallia mariesii: 10.1248/CPB.38.347
328206 - Davallia trichomanoides: 10.1248/CPB.38.347
1179 - Desmonostoc muscorum: 10.1111/J.1432-1033.1985.TB08982.X
397682 - Diplopterygium glaucum: 10.1248/CPB.42.377
97234 - Dryopteris crassirhizoma:
1854 - Frankia: 10.1046/J.1432-1327.2001.02348.X
3274 - Gleichenia japonica: 10.1248/CPB.42.377
126678 - Goniophlebium formosanum: 10.1016/S0031-9422(00)80275-7
253746 - Goniophlebium mengtzeense: 10.1016/S0031-9422(97)00090-3
126675 - Goniophlebium niponicum: 10.1016/S0031-9422(00)80275-7
126675 - Goniophlebium niponicum: 10.1016/S0031-9422(97)00090-3
328223 - Oleandra wallichii: 10.1248/YAKUSHI1947.111.2_120
218620 - Phlebodium aureum: 10.1002/PCA.2800060106
264783 - Plicanthus hirtellus: 10.1002/JCCS.200200091
664672 - Polypodium subpetiolatum: 10.1021/NP50002A006
872808 - Polypodium virginianum: 10.1248/CPB.37.560
58048 - Polypodium vulgare: 10.1248/CPB.37.560
187374 - Pyrrosia lingua: 10.1248/CPB.45.590
746522 - Pyrrosia petiolosa: 10.1080/1028602031000066843
42684 - Streptomyces collinus: 10.1007/S10295-015-1685-7
67294 - Streptomyces filamentosus: 10.1080/14786419.2018.1484457
59299 - Streptomyces thermocarboxydus: 10.1007/S00253-019-10240-3
644122 - Wettsteinia inversa:
33090 - 石韦: -
33090 - 蕤仁: -
33090 - 贯众: -
33090 - 骨碎补: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Dayane S Alvares, Matias Crosio, Natalia Wilke. Hopanoid Hopene Locates in the Interior of Membranes and Affects Their Properties. Langmuir : the ACS journal of surfaces and colloids. 2021 10; 37(40):11900-11908. doi: 10.1021/acs.langmuir.1c02030. [PMID: 34585578]
Jonna Bouwknegt, Sanne J Wiersma, Raúl A Ortiz-Merino, Eline S R Doornenbal, Petrik Buitenhuis, Martin Giera, Christoph Müller, Jack T Pronk. A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-limited anaerobic environments. Proceedings of the National Academy of Sciences of the United States of America. 2021 08; 118(32):. doi: 10.1073/pnas.2105225118. [PMID: 34353908]
Kang He, Lin-Lin Fan, Tian-Tai Wu, Jiang Du. A new xanthone glycoside from Pyrrosia sheareri. Natural product research. 2019 Oct; 33(20):2982-2987. doi: 10.1080/14786419.2018.1514398. [PMID: 30488728]
M N Melo, H I Ingólfsson, S J Marrink. Parameters for Martini sterols and hopanoids based on a virtual-site description. The Journal of chemical physics. 2015 Dec; 143(24):243152. doi: 10.1063/1.4937783. [PMID: 26723637]
Amy B Banta, Jeremy H Wei, Paula V Welander. A distinct pathway for tetrahymanol synthesis in bacteria. Proceedings of the National Academy of Sciences of the United States of America. 2015 Nov; 112(44):13478-83. doi: 10.1073/pnas.1511482112. [PMID: 26483502]
David Poger, Alan E Mark. The relative effect of sterols and hopanoids on lipid bilayers: when comparable is not identical. The journal of physical chemistry. B. 2013 Dec; 117(50):16129-40. doi: 10.1021/jp409748d. [PMID: 24299489]
Y Subhash, L Tushar, Ch Sasikala, Ch V Ramana. Falsirhodobacter halotolerans gen. nov., sp. nov., isolated from dry soils of a solar saltern. International journal of systematic and evolutionary microbiology. 2013 Jun; 63(Pt 6):2132-2137. doi: 10.1099/ijs.0.044107-0. [PMID: 23104358]
M Vyssotski, K C-Y Lee, K Lagutin, J Ryan, X C Morgan, M B Stott. Fatty Acids of Chthonomonas calidirosea, of a novel class Chthonomonadetes from a recently described phylum Armatimonadetes. Lipids. 2011 Dec; 46(12):1155-61. doi: 10.1007/s11745-011-3597-2. [PMID: 21805326]
Ryan F Seipke, Rosemary Loria. Hopanoids are not essential for growth of Streptomyces scabies 87-22. Journal of bacteriology. 2009 Aug; 191(16):5216-23. doi: 10.1128/jb.00390-09. [PMID: 19502399]
Martin Blumenberg, Birte I Oppermann, Rémy Guyoneaud, Walter Michaelis. Hopanoid production by Desulfovibrio bastinii isolated from oilfield formation water. FEMS microbiology letters. 2009 Apr; 293(1):73-8. doi: 10.1111/j.1574-6968.2009.01520.x. [PMID: 19222571]
Thomas Härtner, Kristina L Straub, Elmar Kannenberg. Occurrence of hopanoid lipids in anaerobic Geobacter species. FEMS microbiology letters. 2005 Feb; 243(1):59-64. doi: 10.1016/j.femsle.2004.11.039. [PMID: 15668001]
Cécile Joyeux, Samuel Fouchard, Pierre Llopiz, Serge Neunlist. Influence of the temperature and the growth phase on the hopanoids and fatty acids content of Frateuria aurantia (DSMZ 6220). FEMS microbiology ecology. 2004 Mar; 47(3):371-9. doi: 10.1016/s0168-6496(03)00302-7. [PMID: 19712325]
K Poralla, G Muth, T Härtner. Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2). FEMS microbiology letters. 2000 Aug; 189(1):93-5. doi: 10.1111/j.1574-6968.2000.tb09212.x. [PMID: 10913872]