Sanazin (BioDeep_00000605729)
PANOMIX_OTCML-2023
代谢物信息卡片
5-methyl-1(5H)-phenazinone
化学式: C13H10N2O (210.079309)
中文名称: 綠膿素
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 16.22%
分子结构信息
SMILES: CN1C2=CC=CC=C2N=C3C1=CC=CC3=O
InChI: InChI=1S/C13H10N2O/c1-15-10-6-3-2-5-9(10)14-13-11(15)7-4-8-12(13)16/h2-8H,1H3
描述信息
Pyocyanin (Pyocyanine) is a phenazine that is a toxic, quorum sensing (QS)-controlled metabolite produced by P. aeruginosa. Pyocyanin is a redox-active compound and promotes the generation of reactive oxygen species (ROS). Pyocyanin also possesses antibacterial properties and increases fitness in competition with other bacterial species[1].
同义名列表
6 个代谢物同义名
5-methyl-1(5H)-phenazinone; Pyrocyanine; Pyocyanine; Pyocyanin; Sanazin; Sanasin
数据库引用编号
6 个数据库交叉引用编号
- PubChem: 6817
- Metlin: METLIN64675
- ChEMBL: CHEMBL2289232
- MeSH: Pyocyanine
- CAS: 85-66-5
- medchemexpress: HY-111278
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aditi Buch, Vaishnawi Gupta. Unusual concurrence of P-solubilizing and biocontrol traits under P-limitation in plant-beneficial Pseudomonas aeruginosa P4: insights from in vitro metabolic and gene expression analysis.
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Microbial biotechnology.
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2020 01; 10(1):1542. doi:
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2019 12; 85(24):. doi:
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2015 Jan; 60(1):8-19. doi:
10.1111/lam.12343. [PMID: 25346138] - Noha Nafee, Ayman Husari, Christine K Maurer, Cenbin Lu, Chiara de Rossi, Anke Steinbach, Rolf W Hartmann, Claus-Michael Lehr, Marc Schneider. Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors.
Journal of controlled release : official journal of the Controlled Release Society.
2014 Oct; 192(?):131-40. doi:
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Biosensors & bioelectronics.
2014 Oct; 60(?):265-70. doi:
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Food chemistry.
2014 Sep; 159(?):451-7. doi:
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Microbiology and immunology.
2014 May; 58(5):286-93. doi:
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Molecules (Basel, Switzerland).
2014 Apr; 19(4):4189-99. doi:
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Molecular plant-microbe interactions : MPMI.
2014 Apr; 27(4):364-78. doi:
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PloS one.
2014; 9(2):e98985. doi:
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Archives of medical research.
2013 Oct; 44(7):488-94. doi:
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Natural product communications.
2013 Oct; 8(10):1455-8. doi:
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Journal of agricultural and food chemistry.
2013 Feb; 61(8):1794-803. doi:
10.1021/jf305164m. [PMID: 23379671] - Eunkyoung Kim, Tanya Gordonov, William E Bentley, Gregory F Payne. Amplified and in situ detection of redox-active metabolite using a biobased redox capacitor.
Analytical chemistry.
2013 Feb; 85(4):2102-8. doi:
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The Biochemical journal.
2012 Jun; 444(3):445-55. doi:
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PloS one.
2012; 7(4):e36090. doi:
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PloS one.
2012; 7(5):e38148. doi:
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Vojnosanitetski pregled.
2011 Nov; 68(11):923-9. doi:
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Journal of natural products.
2011 Oct; 74(10):2261-4. doi:
10.1021/np100872k. [PMID: 21910441] - Ekta Khare, Naveen Kumar Arora. Dual activity of pyocyanin from Pseudomonas aeruginosa--antibiotic against phytopathogen and signal molecule for biofilm development by rhizobia.
Canadian journal of microbiology.
2011 Sep; 57(9):708-13. doi:
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Microbiology (Reading, England).
2011 Jul; 157(Pt 7):2120-2132. doi:
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Canadian journal of physiology and pharmacology.
2011 Jun; 89(6):419-27. doi:
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Mucosal immunology.
2011 Mar; 4(2):158-71. doi:
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The West Indian medical journal.
2011 Jan; 60(1):24-32. doi:
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Bioorganic & medicinal chemistry.
2010 Jun; 18(12):4269-74. doi:
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Environmental microbiology.
2010 Jun; 12(6):1659-73. doi:
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Applied microbiology and biotechnology.
2010 May; 86(6):1659-70. doi:
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Chemotherapy.
2010; 56(4):333-9. doi:
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Applied biochemistry and biotechnology.
2008 Dec; 151(2-3):665-75. doi:
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Applied microbiology and biotechnology.
2008 Jul; 79(5):843-58. doi:
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Journal of agricultural and food chemistry.
2008 Mar; 56(6):1955-62. doi:
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Biochemistry.
2007 Feb; 46(7):1821-8. doi:
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Molecular plant-microbe interactions : MPMI.
2006 Dec; 19(12):1406-19. doi:
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Journal of the Egyptian Society of Parasitology.
2006 Apr; 36(1):197-220. doi:
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Infection and immunity.
2005 Sep; 73(9):5319-28. doi:
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Investigative ophthalmology & visual science.
2005 Jan; 46(1):248-51. doi:
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Molecular plant-microbe interactions : MPMI.
2002 Nov; 15(11):1147-56. doi:
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Journal of bacteriology.
2001 Dec; 183(24):7126-34. doi:
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