D-Luciferin (BioDeep_00000004986)
代谢物信息卡片
化学式: C11H8N2O3S2 (279.9976)
中文名称: D-荧光素, 螢蟲素
谱图信息:
最多检出来源 Homo sapiens(lipidsearch) 34.33%
分子结构信息
SMILES: C1C(N=C(S1)C2=NC3=C(S2)C=C(C=C3)O)C(=O)O
InChI: InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1
描述信息
同义名列表
7 个代谢物同义名
Firefly luciferin; D-Luciferin; (S)-4,5-Dihydro-2-(6-hydroxy-1,3-benzothiazol-2-yl)thiazole-4-carboxylic acid; (S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid; 2-(6-Hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid; Photinus luciferin; Photinus luciferin
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:17165
- KEGG: C02740
- PubChem: 92934
- PubChem: 616547
- Metlin: METLIN65823
- ChEMBL: CHEMBL443738
- CAS: 2591-17-5
- CAS: 55963-96-7
- PMhub: MS000017653
- PubChem: 5700
- PDB-CCD: ESJ
- NIKKAJI: J7.623F
- RefMet: Photinus luciferin
- KNApSAcK: 17165
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Julia Günter, Roland H Wenger, Carsten C Scholz. Inhibition of firefly luciferase activity by a HIF prolyl hydroxylase inhibitor.
Journal of photochemistry and photobiology. B, Biology.
2020 Sep; 210(?):111980. doi:
10.1016/j.jphotobiol.2020.111980. [PMID: 32745950] - Shuang Li, Rui Hu, Chenlin Yang, Xin Zhang, Yi Zeng, Shuangqing Wang, Xudong Guo, Yi Li, Xiaopin Cai, Shirui Li, Chengwu Han, Guoqiang Yang. An ultrasensitive bioluminogenic probe of γ-Glutamyltranspeptidase in vivo and in human serum for tumor diagnosis.
Biosensors & bioelectronics.
2017 Dec; 98(?):325-329. doi:
10.1016/j.bios.2017.06.059. [PMID: 28697445] - Apurva R Patel, Ed Lim, Kevin P Francis, Mandip Singh. Opening up the optical imaging window using nano-luciferin.
Pharmaceutical research.
2014 Nov; 31(11):3073-84. doi:
10.1007/s11095-014-1400-9. [PMID: 24831312] - P Stephen Patrick, Scott K Lyons, Tiago B Rodrigues, Kevin M Brindle. Oatp1 enhances bioluminescence by acting as a plasma membrane transporter for D-luciferin.
Molecular imaging and biology.
2014 Oct; 16(5):626-34. doi:
10.1007/s11307-014-0741-4. [PMID: 24798747] - Stephanie David, Nathalie Carmoy, Pauline Resnier, Caroline Denis, Laurent Misery, Bruno Pitard, Jean-Pierre Benoit, Catherine Passirani, Tristan Montier. In vivo imaging of DNA lipid nanocapsules after systemic administration in a melanoma mouse model.
International journal of pharmaceutics.
2012 Feb; 423(1):108-15. doi:
10.1016/j.ijpharm.2011.06.031. [PMID: 21726617] - Azadeh Kheirolomoom, Dustin E Kruse, Shengping Qin, Katherine E Watson, Chun-Yen Lai, Lawrence J T Young, Robert D Cardiff, Katherine W Ferrara. Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system.
Journal of controlled release : official journal of the Controlled Release Society.
2010 Jan; 141(2):128-36. doi:
10.1016/j.jconrel.2009.08.029. [PMID: 19748536] - Frank Berger, Ramasamy Paulmurugan, Srabani Bhaumik, Sanjiv Sam Gambhir. Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging.
European journal of nuclear medicine and molecular imaging.
2008 Dec; 35(12):2275-85. doi:
10.1007/s00259-008-0870-6. [PMID: 18661130] - S Husted, T Hjort. Sperm antibodies in serum and seminal plasma.
International journal of fertility.
1975; 20(2):97-105. doi:
NULL. [PMID: 3485]
