Oxytocin (BioDeep_00000004477)

 

Secondary id: BioDeep_00001867847

human metabolite Endogenous


代谢物信息卡片


(2S)-2-[({1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentahydroxy-10-[2-(C-hydroxycarbonimidoyl)ethyl]-7-[(C-hydroxycarbonimidoyl)methyl]-16-[(4-hydroxyphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaene-4-carbonyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-N-[(C-hydroxycarbonimidoyl)methyl]-4-methylpentanimidate

化学式: C43H66N12O12S2 (1006.4364)
中文名称: 缩宫素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
InChI: InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)

描述信息

Oxytocin is a mammalian hormone that also acts as a neurotransmitter in the brain. In women, it is released mainly after distention of the cervix and vagina during labor, and after stimulation of the nipples, facilitating birth and breastfeeding, respectively. Oxytocin is released during orgasm in both sexes. In the brain, oxytocin is involved in social recognition and bonding, and might be involved in the formation of trust between people. -- Wikipedia; In the pituitary gland, oxytocin is packaged in large, dense-core vesicles, where it is bound to neurophysin as shown in the inset of the figure; neurophysin is a large peptide fragment of the giant precursor protein molecule from which oxytocin is derived by enzymatic cleavage. -- Wikipedia; Oxytocin is a peptide of nine amino acids (a nonapeptide). The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG). The cysteine residues form a sulfur bridge. Oxytocin has a molecular mass of 1007 daltons. One international unit (IU) of oxytocin is the equivalent of about 2 micrograms of pure peptide. -- Wikipedia; Oxytocin has peripheral (hormonal) actions, and also has actions in the brain. The actions of oxytocin are mediated by specific, high affinity oxytocin receptors. The oxytocin receptor is a G-protein-coupled receptor which requires Mg2+ and cholesterol. It belongs to the rhodopsin-type (class I) group of G-protein-coupled receptors. -- Wikipedia [HMDB]
Oxytocin is a mammalian hormone that also acts as a neurotransmitter in the brain. In women, it is released mainly after distention of the cervix and vagina during labor, and after stimulation of the nipples, facilitating birth and breastfeeding, respectively. Oxytocin is released during orgasm in both sexes. In the brain, oxytocin is involved in social recognition and bonding, and might be involved in the formation of trust between people. -- Wikipedia; In the pituitary gland, oxytocin is packaged in large, dense-core vesicles, where it is bound to neurophysin as shown in the inset of the figure; neurophysin is a large peptide fragment of the giant precursor protein molecule from which oxytocin is derived by enzymatic cleavage. -- Wikipedia; Oxytocin is a peptide of nine amino acids (a nonapeptide). The sequence is cysteine - tyrosine - isoleucine - glutamine - asparagine - cysteine - proline - leucine - glycine (CYIQNCPLG). The cysteine residues form a sulfur bridge. Oxytocin has a molecular mass of 1007 daltons. One international unit (IU) of oxytocin is the equivalent of about 2 micrograms of pure peptide. -- Wikipedia; Oxytocin has peripheral (hormonal) actions, and also has actions in the brain. The actions of oxytocin are mediated by specific, high affinity oxytocin receptors. The oxytocin receptor is a G-protein-coupled receptor which requires Mg2+ and cholesterol. It belongs to the rhodopsin-type (class I) group of G-protein-coupled receptors. -- Wikipedia.
H - Systemic hormonal preparations, excl. sex hormones and insulins > H01 - Pituitary and hypothalamic hormones and analogues > H01B - Posterior pituitary lobe hormones > H01BB - Oxytocin and analogues
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2348 - Pituitary Agent
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D012102 - Reproductive Control Agents > D010120 - Oxytocics
Corona-virus
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Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma[1][2].

同义名列表

30 个代谢物同义名

(2S)-2-[({1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-[(2S)-butan-2-yl]-6,9,12,15,18-pentahydroxy-10-[2-(C-hydroxycarbonimidoyl)ethyl]-7-[(C-hydroxycarbonimidoyl)methyl]-16-[(4-hydroxyphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaene-4-carbonyl]pyrrolidin-2-yl}(hydroxy)methylidene)amino]-N-[(C-hydroxycarbonimidoyl)methyl]-4-methylpentanimidate; (2S)-2-({1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-[(2S)-butan-2-yl]-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl]pyrrolidin-2-yl}formamido)-N-(carbamoylmethyl)-4-methylpentanamide; Cys-tyr-ile-GLN-asn-cys-pro-leu-gly-NH2; Cys-tyr-ile-THR-asn-cys-gly-leu-gly-NH2; Cys-tyr-phe-GLN-asn-cys-pro-lys-gly-NH2; Cys-tyr-ile-GLN-asn-cys-pro-arg-gly-NH2; Cys-tyr-phe-GLN-asn-cys-pro-arg-gly-NH2; Oxytocin 20 usp units in dextrose 5\\%; Oxytocin 10 usp units in dextrose 5\\%; Oxytocin 5 usp units in dextrose 5\\%; Oxytocin acetate salt hydrate; Biotinyl-(arg8)-vasopressin; Disulfide bridge cys1-cys6; Oxytocin acetate salt; Oxytocin injection; Argpressin acetate; (Arg8)-vasopressin; alpha-Hypophamine; (Arg8)-vasotocin; Oxytocin acetate; Gly-leu-pro-c; Argipressin; Syntocinon; Ocytocin; Oxytocin; Pitocin; OXT; α-Hypophamine; Oxytocic hormone; Oxytocin



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 AKT1, DBH, EDN1, ESR1, MC4R
Peripheral membrane protein 2 AP1S2, ESR1
Nucleus 2 AKT1, ESR1
cytosol 4 AKT1, AP1S2, ESR1, LEP
nucleoplasm 2 AKT1, ESR1
Cell membrane 3 AKT1, ESR1, MC4R
Cytoplasmic side 2 AP1S2, ESR1
lamellipodium 1 AKT1
Multi-pass membrane protein 2 CACNA1I, MC4R
Synapse 3 DBH, NPS, TAC1
cell cortex 1 AKT1
cell surface 1 CD38
glutamatergic synapse 2 AKT1, GHRL
Golgi apparatus 2 AP1S2, ESR1
Golgi membrane 2 AP1S2, INS
lysosomal membrane 2 AP1S2, EGF
neuronal cell body 1 TAC1
postsynapse 2 AKT1, GHRL
Cytoplasmic vesicle, secretory vesicle 1 NTS
plasma membrane 8 AKT1, CACNA1I, CD38, EGF, ESR1, IFNLR1, KNG1, MC4R
Membrane 8 AKT1, CACNA1I, CD38, DBH, EGF, ESR1, IFNLR1, MC4R
axon 2 GHRL, TAC1
basolateral plasma membrane 1 CD38
extracellular exosome 3 CD38, EGF, KNG1
endoplasmic reticulum 1 DBH
extracellular space 10 DBH, EDN1, EGF, GHRL, GNRH1, IGF1, INS, KNG1, LEP, TAC1
Schaffer collateral - CA1 synapse 1 GHRL
protein-containing complex 2 AKT1, ESR1
intracellular membrane-bounded organelle 3 AP1S2, DBH, NTS
Single-pass type I membrane protein 1 IFNLR1
Secreted 8 DBH, EDN1, GHRL, IGF1, INS, LEP, NTS, TRH
extracellular region 13 DBH, EDN1, EGF, GHRL, GNRH1, IGF1, INS, KNG1, LEP, NPS, NTS, TAC1, TRH
basal part of cell 1 EDN1
transcription regulator complex 1 ESR1
centriolar satellite 1 DBH
nuclear membrane 1 CD38
neuronal dense core vesicle lumen 1 GHRL
microtubule cytoskeleton 1 AKT1
Early endosome 1 AP1S2
Membrane, clathrin-coated pit 1 AP1S2
cell-cell junction 1 AKT1
clathrin-coated pit 1 AP1S2
Single-pass type II membrane protein 2 CD38, DBH
vesicle 1 AKT1
spindle 1 AKT1
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
collagen-containing extracellular matrix 1 KNG1
secretory granule 1 TRH
ciliary basal body 1 AKT1
chromatin 1 ESR1
Secreted, extracellular space 1 KNG1
blood microparticle 1 KNG1
Endomembrane system 1 AP1S2
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 AP1S2
euchromatin 1 ESR1
trans-Golgi network membrane 1 AP1S2
exocytic vesicle 1 IGF1
secretory granule lumen 3 DBH, GHRL, INS
secretory granule membrane 1 DBH
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 GHRL, INS, KNG1
platelet alpha granule lumen 3 EGF, IGF1, KNG1
axon terminus 1 NTS
voltage-gated calcium channel complex 1 CACNA1I
transport vesicle 3 EDN1, INS, NTS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 EGF
[Isoform 1]: Nucleus 1 ESR1
AP-type membrane coat adaptor complex 1 AP1S2
membrane coat 1 AP1S2
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
AP-1 adaptor complex 1 AP1S2
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
transport vesicle membrane 1 DBH
rough endoplasmic reticulum lumen 1 EDN1
Weibel-Palade body 1 EDN1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
interleukin-28 receptor complex 1 IFNLR1


文献列表

  • Su-Ting Jiang, Shu-Ying Lian, Yao-Huan Sun, Mei-Bo Pan, Bin Wang, Hui Wang, Jun Hua, Yi-Chen Wang, Qiu-Ling Wang, Yin-Feng Dong. The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice. Experimental gerontology. 2024 Jun; 190(?):112432. doi: 10.1016/j.exger.2024.112432. [PMID: 38614224]
  • Antonina I Frolova, Kevin K Prifti, Nandini Raghuraman, Ebony B Carter, Sarah K England, Molly J Stout. Association between Maternal Serum Lipids and Intrapartum Oxytocin Requirements during Labor Induction and Augmentation. American journal of perinatology. 2024 May; 41(S 01):e1015-e1022. doi: 10.1055/a-1979-8577. [PMID: 36384236]
  • Gisele Almeida Lopes, Thais Trevisan Teixeira, Nathalie Leister, Maria Luiza Riesco. Methods of induction and augmentation of labor in a freestanding birth center: a cross-sectional study. Revista da Escola de Enfermagem da U S P. 2024; 57(?):e20230158. doi: 10.1590/1980-220x-reeusp-2023-0158en. [PMID: 38324551]
  • Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shingen Misaka, Tomoyuki Ono, Hiroaki Oizumi, Keita Mizuno, Shizu Hidema, Katsuhiko Nishimori, Masato Aoyama, Heidi de Wet, Kenju Shimomura. Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice. Frontiers in endocrinology. 2024; 15(?):1387964. doi: 10.3389/fendo.2024.1387964. [PMID: 38742193]
  • Erwei Li, Luhong Wang, Daqing Wang, Jingyi Chi, Zeran Lin, Gordon I Smith, Samuel Klein, Paul Cohen, Evan D Rosen. Control of lipolysis by a population of oxytocinergic sympathetic neurons. Nature. 2024 Jan; 625(7993):175-180. doi: 10.1038/s41586-023-06830-x. [PMID: 38093006]
  • Liang Wu, Ying Yang, Min Lin, Haiqing Wang, Luqian Li, Haixia Wu, Xue Wang, Ming Yan. Unraveling the anti-primary dysmenorrhea mechanism of Ainsliaea fragrans Champ. extract by the integrative approach of network pharmacology and experimental verification. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155213. doi: 10.1016/j.phymed.2023.155213. [PMID: 37980805]
  • Sayah Ongsricharoenbhorn, Pakanit Kupittayanant, Kanjana Thumanu, Griangsak Eumkeb, Suthida Chanlun, Pittaya Papirom, Susan Wray, Sajeera Kupittayanant. Effects of Heliotropium indicum L. on Uterine Involution and Its Underlying Mechanisms: an in vivo and in vitro Study. Chinese journal of integrative medicine. 2023 Nov; 29(11):980-988. doi: 10.1007/s11655-023-3742-9. [PMID: 37608039]
  • Liu-Jun Wu, Yan Chen, Zi-Wei Lin, Chen Sun, Liang Xiong, Xiao-Fang Xie, Cheng Peng. [Therapeutic effect of Leonuri Herba aqueous decoction on primary dysmenorrhea in rats and its metabolomic analysis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2023 Nov; 48(22):6093-6106. doi: 10.19540/j.cnki.cjcmm.20230803.401. [PMID: 38114217]
  • Hilal Korkmaz, Canan Dura Deveci, Yusuf Üstün, Bilge Pehlivanoğlu. Comparison of plasma oxytocin level in women with natural and surgical menopause. Endocrine. 2023 10; 82(1):209-214. doi: 10.1007/s12020-023-03453-0. [PMID: 37477780]
  • Alexander V Sirotkin, Adam Tarko, Zuzana Fabova, Igor Valocky, Saleh Alwasel, Jan Kotwica, Abdel Halim Harrath. Can flaxseed, chia or puncture vine affect mare ovarian cell functions and prevent the toxic effect of the environmental contaminant toluene?. Theriogenology. 2023 Sep; 208(?):178-184. doi: 10.1016/j.theriogenology.2023.06.018. [PMID: 37354861]
  • Feiye Wu, Jing Zhu, Yang Wan, Subinuer Kurexi, Jia Zhou, Ke Wang, Tongyu Chen. Electroacupuncture Ameliorates Hypothalamic‒Pituitary‒Adrenal Axis Dysfunction Induced by Surgical Trauma in Mice Through the Hypothalamic Oxytocin System. Neurochemical research. 2023 Jul; ?(?):. doi: 10.1007/s11064-023-03984-y. [PMID: 37436613]
  • Yi Zhang, Yangyang Zhu, Jinghui Wang, Li Jin, Mingwei Guo, Liwei Chen, Lina Zhang, Yangyang Li, Baocheng Wan, Rong Zhang, Weiping Jia, Cheng Hu. Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2023 06; 10(16):e2204824. doi: 10.1002/advs.202204824. [PMID: 37060105]
  • Fu-Guang Wang, Yi Sun, Juan Cao, Xu-Ri Shen, Fu-Wang Liu, Shuang-Shuang Song, Xue-Qin Hou, Lei Yin. Effects of Danggui-Shaoyao-San on central neuroendocrine and pharmacokinetics in female ovariectomized rats. Journal of ethnopharmacology. 2023 May; ?(?):116609. doi: 10.1016/j.jep.2023.116609. [PMID: 37150422]
  • A V Sirotkin, A Tarko, J Kotwica, M Mlyncek, S Alwasel, S Nitrayova, A H Harrath. Three medicinal plants affecting human ovarian cell viability, hormone release, and response to environmental contaminant toluene. Physiological research. 2023 Apr; 72(2):259-268. doi: . [PMID: 37159859]
  • Yanqu Zhou, Mei Liu, Xiuxiu Liu, Rulan Jiang, Yunan He, Qian Yao, Hong Chen, Chunmei Fu. Rapid and sensitive fluorescence determination of oxytocin using nitrogen-doped carbon dots as fluorophores. Journal of pharmaceutical and biomedical analysis. 2023 Mar; 229(?):115344. doi: 10.1016/j.jpba.2023.115344. [PMID: 36966622]
  • Alexander V Sirotkin, Martina Macejková, Adam Tarko, Zuzana Fabova, Saleh Alwasel, Jan Kotwica, Abdel Halim Harrath. Ginkgo, fennel, and flaxseed can affect hormone release by porcine ovarian cells and modulate the effect of toluene. Reproductive biology. 2023 Mar; 23(1):100736. doi: 10.1016/j.repbio.2023.100736. [PMID: 36773449]
  • D E Olazábal, N Pillay, N Sandberg, K-J Hartman. Description and comparison of brain distribution of oxytocin receptors in Rhabdomys pumillio and Rhabdomys dilectus. General and comparative endocrinology. 2023 Jan; 335(?):114224. doi: 10.1016/j.ygcen.2023.114224. [PMID: 36702289]
  • C C Cingi, D Eroglu. Efficacy of nasal stimulants on interpersonal communication - a narrative review. European review for medical and pharmacological sciences. 2022 12; 26(2 Suppl):99-102. doi: 10.26355/eurrev_202212_30492. [PMID: 36524917]
  • Nara Lins Meira Quintão, Jaqueline Pavesi Reis, Larissa Benvenutti, Roberta Nunes, Fernanda Capitanio Goldoni, Manuela Somensi Cozer, Priscila de Souza, Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva, Jessica Melato, Carlos Rafael Vaz, Juliana Cristina Pereira Whitaker, Flavia Werner Jesuíno, Mariana Couto Costa, Maria Verônica Dávila Pastor, Angela Malheiros, Christiane Meyre-Silva, José Roberto Santin. Involvement of a neutrophil-mast cell axis in the effects of Piper malacophyllum (C. PESL) C. DC extract and its isolated compounds in a mouse model of dysmenorrhoea. Inflammopharmacology. 2022 Dec; 30(6):2489-2504. doi: 10.1007/s10787-022-01032-9. [PMID: 35867292]
  • Xiaoqin Liu, Xianglong Meng, Xiaojuan Su, Kele Ren, Chenxu Ning, Xiaoming Qi, Shuosheng Zhang. The mechanism of ginger and its processed products in the treatment of estradiol valerate coupled with oxytocin-induced dysmenorrhea in mice via regulating the TRP ion channel-mediated ERK1/2/NF-κB signaling pathway. Food & function. 2022 Oct; 13(21):11236-11248. doi: 10.1039/d2fo01845d. [PMID: 36222424]
  • Adriano Winterton, Francesco Bettella, Dani Beck, Tiril P Gurholt, Nils Eiel Steen, Linn Rødevand, Lars T Westlye, Ole A Andreassen, Daniel S Quintana. The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health. Psychoneuroendocrinology. 2022 10; 144(?):105875. doi: 10.1016/j.psyneuen.2022.105875. [PMID: 35939863]
  • Terigele Bao, Lan Feng, Sungbo Cho, Hongzhen Yu, Wenjie Jin, Lili Dai, Junqing Zhang, Laxinamujila Bai, Minghai Fu, Yongsheng Chen. RNA-Seq Reveals Protective Mechanisms of Mongolian Medicine Molor-Dabos-4 on Acute Indomethacin-Induced Gastric Ulcers in Rats. Genes. 2022 Sep; 13(10):. doi: 10.3390/genes13101740. [PMID: 36292625]
  • Mitchell Ty Ringuet, John Barton Furness, Sebastian George Barton Furness. G protein-coupled receptor interactions and modification of signalling involving the ghrelin receptor, GHSR1a. Journal of neuroendocrinology. 2022 09; 34(9):e13077. doi: 10.1111/jne.13077. [PMID: 34931385]
  • Boya Huang, Binhuang Sun, Rui Yang, Shihao Liang, Xinrui Li, Yi Guo, Qian Meng, Yaling Fu, Wenshuya Li, Penghui Zhao, Miao Gong, Yun Shi, Li Song, Sheng Wang, Fang Yuan, Haishui Shi. Long-lasting effects of postweaning sleep deprivation on cognitive function and social behaviors in adult mice. Neuropharmacology. 2022 09; 215(?):109164. doi: 10.1016/j.neuropharm.2022.109164. [PMID: 35716724]
  • Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Metz. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters. Cerebral cortex (New York, N.Y. : 1991). 2022 07; 32(14):2985-2999. doi: 10.1093/cercor/bhab395. [PMID: 35059698]
  • Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Senturk. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage. ACS chemical neuroscience. 2022 07; 13(13):1923-1937. doi: 10.1021/acschemneuro.2c00124. [PMID: 35713692]
  • Sarah J Baracz, Katherine J Robinson, Amanda L Wright, Anita J Turner, Iain S McGregor, Jennifer L Cornish, Nicholas A Everett. Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022 07; 47(8):1561-1573. doi: 10.1038/s41386-022-01336-y. [PMID: 35581382]
  • Angela C Incollingo Rodriguez, Laura Smith, Rebeca Harris, Benjamin C Nephew, Hudson P Santos, Chris Murgatroyd. Oxytocin modulates sensitivity to acculturation and discrimination stress in pregnancy. Psychoneuroendocrinology. 2022 07; 141(?):105769. doi: 10.1016/j.psyneuen.2022.105769. [PMID: 35462200]
  • Katja Hoehne, Pascal Vrtička, Veronika Engert, Tania Singer. Plasma oxytocin is modulated by mental training, but does not mediate its stress-buffering effect. Psychoneuroendocrinology. 2022 07; 141(?):105734. doi: 10.1016/j.psyneuen.2022.105734. [PMID: 35367715]
  • Benjamin A Tabak, David Rosenfield, Cecile S Sunahara, Talha Alvi, Angela Szeto, Armando J Mendez. Social anxiety is associated with greater peripheral oxytocin reactivity to psychosocial stress. Psychoneuroendocrinology. 2022 06; 140(?):105712. doi: 10.1016/j.psyneuen.2022.105712. [PMID: 35306471]
  • Juan Liu, Rui Feng, Ou Dai, Hong Ni, Lu-Si Liu, Hong-Zhen Shu, Yan Lu, Cheng Peng, Liang Xiong. Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle. Phytochemistry. 2022 Jun; 198(?):113159. doi: 10.1016/j.phytochem.2022.113159. [PMID: 35283167]
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