Mandelonitrile (BioDeep_00000004449)

Main id: BioDeep_00000019504

Secondary id: BioDeep_00000015404

human metabolite natural product


代谢物信息卡片


(R)-(+)-ALPHA-HYDROXYBENZENE-ACETONITRILE

化学式: C8H7NO (133.0528)
中文名称: (R)-(+)-苯乙醇腈, 扁桃腈
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C(C#N)O
InChI: InChI=1S/C8H7NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H/t8-/m0/s1

描述信息

Mandelonitrile is a chemical compound of the cyanohydrin class. Small amounts of mandelonitrile occur in the pits of some fruits. (Wikipedia)

同义名列表

10 个代谢物同义名

(R)-(+)-ALPHA-HYDROXYBENZENE-ACETONITRILE; (2R)-2-hydroxy-2-phenylacetonitrile; Benzaldehyde cyanohydrin; (R)-(+)-Mandelonitrile; (-)-mandelonitrile; (+)-Mandelonitrile; (R)-Mandelonitrile; D-Mandelonitrile; Mandelonitrile; Mandelonitrile



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(3)

PlantCyc(3)

代谢反应

43 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(3)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(40)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

13 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 BCL2, CASP3, PFDN5, PTGS2
Peripheral membrane protein 2 CYP1B1, PTGS2
Endoplasmic reticulum membrane 3 BCL2, CYP1B1, PTGS2
Nucleus 3 BCL2, CASP3, PFDN5
cytosol 3 BCL2, CASP3, PFDN5
nucleoplasm 1 CASP3
Multi-pass membrane protein 1 SLC5A1
glutamatergic synapse 1 CASP3
neuronal cell body 1 CASP3
plasma membrane 2 IGHE, SLC5A1
Membrane 2 BCL2, CYP1B1
apical plasma membrane 1 SLC5A1
caveola 1 PTGS2
extracellular exosome 1 SLC5A1
endoplasmic reticulum 2 BCL2, PTGS2
extracellular space 1 IGHE
perinuclear region of cytoplasm 1 SLC5A1
mitochondrion 2 BCL2, CYP1B1
protein-containing complex 2 BCL2, PTGS2
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 2 CYP1B1, PTGS2
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 IGHE
extracellular region 2 DNAH9, IGHE
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
motile cilium 1 DNAH9
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
Early endosome 1 SLC5A1
Apical cell membrane 1 SLC5A1
pore complex 1 BCL2
microtubule 1 DNAH9
intracellular vesicle 1 SLC5A1
axoneme 1 DNAH9
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
IgE immunoglobulin complex 1 IGHE
brush border membrane 1 SLC5A1
Cytoplasm, cytoskeleton, cilium axoneme 1 DNAH9
[Isoform 2]: Cell membrane 1 IGHE
myelin sheath 1 BCL2
intermediate filament cytoskeleton 1 PFDN5
endoplasmic reticulum lumen 1 PTGS2
9+2 motile cilium 1 DNAH9
dynein complex 1 DNAH9
prefoldin complex 1 PFDN5
death-inducing signaling complex 1 CASP3
[Isoform 3]: Cell membrane 1 IGHE
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
BAD-BCL-2 complex 1 BCL2
intracellular organelle 1 SLC5A1
outer dynein arm 1 DNAH9
distal portion of axoneme 1 DNAH9


文献列表

  • Sven Rustler, Hassan Motejadded, Josef Altenbuchner, Andreas Stolz. Simultaneous expression of an arylacetonitrilase from Pseudomonas fluorescens and a (S)-oxynitrilase from Manihot esculenta in Pichia pastoris for the synthesis of (S)-mandelic acid. Applied microbiology and biotechnology. 2008 Aug; 80(1):87-97. doi: 10.1007/s00253-008-1531-1. [PMID: 18523765]
  • Jerome Grimplet, Laurent G Deluc, Richard L Tillett, Matthew D Wheatley, Karen A Schlauch, Grant R Cramer, John C Cushman. Tissue-specific mRNA expression profiling in grape berry tissues. BMC genomics. 2007 Jun; 8(?):187. doi: 10.1186/1471-2164-8-187. [PMID: 17584945]
  • Yasuhisa Asano, Ken'ichirou Tamura, Nobutaka Doi, Techawaree Ueatrongchit, Aran H-Kittikun, Tohru Ohmiya. Screening for new hydroxynitrilases from plants. Bioscience, biotechnology, and biochemistry. 2005 Dec; 69(12):2349-57. doi: 10.1271/bbb.69.2349. [PMID: 16377893]