Dihydroxyacetone (BioDeep_00000004393)
Secondary id: BioDeep_00000267421, BioDeep_00000863183
human metabolite PANOMIX_OTCML-2023 Endogenous
代谢物信息卡片
Summers brand OF dihydroxyacetone
化学式: C3H6O3 (90.0316926)
中文名称: 1,3-二羟基丙酮
谱图信息:
最多检出来源 Macaca mulatta(otcml) 0.09%
分子结构信息
SMILES: C(C(=O)CO)O
InChI: InChI=1S/C3H6O3/c4-1-3(6)2-5/h4-5H,1-2H2
描述信息
Dihydroxyacetone, also known as 1,3-dihydroxy-2-propanone or glycerone, is a member of the class of compounds known as monosaccharides. Monosaccharides are compounds containing one carbohydrate unit not glycosidically linked to another such unit, and no set of two or more glycosidically linked carbohydrate units. Monosaccharides have the general formula CnH2nOn. Dihydroxyacetone is soluble (in water) and a very weakly acidic compound (based on its pKa). Dihydroxyacetone can be found in a number of food items such as cauliflower, green bell pepper, black cabbage, and sweet basil, which makes dihydroxyacetone a potential biomarker for the consumption of these food products. Dihydroxyacetone can be found primarily in urine, as well as in human muscle and stratum corneum tissues. Dihydroxyacetone exists in all living species, ranging from bacteria to humans. Dihydroxyacetone is primarily used as an ingredient in sunless tanning products. It is often derived from plant sources such as sugar beets and sugar cane, and by the fermentation of glycerin .
Dihydroxyacetone (also known as DHA) is a ketotriose compound. Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage. It is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones, it acts as a sunscreening agent. Dihydroxyacetone is the simplest of all ketoses and, having no chiral centre, is the only one that has no optical activity. Dihydroxyacetone is a simple non-toxic sugar. It is often derived from plant sources such as sugar beets and sugar cane, by the fermentation of glycerin. Dihydroxyacetone is a white crystalline powder which is water soluble.
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol over Gluconobacter oxydans[1].
1,3-Dihydroxyacetone (DHA), the main active ingredient in sunless tanning skin-care preparations and an important precursor for the synthesis of various fine chemicals, is produced on an industrial scale by microbial fermentation of glycerol over Gluconobacter oxydans[1].
同义名列表
31 个代谢物同义名
Summers brand OF dihydroxyacetone; ICN brand OF dihydroxyacetone; 1,3-Dihydroxydimethyl ketone; alpha,Alpha-dihydroxyacetone; Dihydroxyacetone (glycerone); Bis(hydroxymethyl) ketone; 1,3-Dihydroxypropan-2-one; 1,3-Dihydroxy-2-propanone; 1,3 Dihydroxy 2 propanone; a,Alpha-dihydroxyacetone; Α,alpha-dihydroxyacetone; 1,3-Dihydroxypropanone; 1,3-Propanediol-2-one; 1,3-Dihydroxyacetone; a,A-dihydroxyacetone; Dihydroxy-acetone; Dihydroxyacetone; Aliphatic ketone; Ketochromin; Chromelin; Viticolor; Glycerone; Triulose; Protosol; Oxantin; Dihyxal; Oxatone; Vitadye; Soleal; Otan; DHA
数据库引用编号
21 个数据库交叉引用编号
- ChEBI: CHEBI:16016
- KEGG: C00184
- KEGGdrug: D07841
- PubChem: 670
- HMDB: HMDB0001882
- Metlin: METLIN3227
- DrugBank: DB01775
- ChEMBL: CHEMBL1229937
- Wikipedia: Dihydroxyacetone
- MeSH: Dihydroxyacetone
- MetaCyc: DIHYDROXYACETONE
- foodb: FDB030826
- chemspider: 650
- CAS: 96-26-4
- PMhub: MS000016814
- PubChem: 3484
- PDB-CCD: 2HA
- 3DMET: B00055
- NIKKAJI: J4.719H
- RefMet: Dihydroxyacetone
- medchemexpress: HY-Y0335
分类词条
相关代谢途径
Reactome(0)
BioCyc(6)
- N-acetylneuraminate and N-acetylmannosamine degradation I
- superpathway of N-acetylglucosamine, N-acetylmannosamine and N-acetylneuraminate degradation
- superpathway of N-acetylneuraminate degradation
- formaldehyde assimilation III (dihydroxyacetone cycle)
- superpathway of glycerol degradation to 1,3-propanediol
- glycerol degradation II
PlantCyc(0)
代谢反应
34 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(25)
- cytidine-5'-diphosphate-glycerol biosynthesis:
H+ + NAD(P)H + dihydroxyacetone ⟶ NAD(P)+ + glycerol - glycerol degradation to butanol:
NAD+ + butan-1-ol ⟶ H+ + NADH + butan-1-al - formaldehyde assimilation III (dihydroxyacetone cycle):
ATP + dihydroxyacetone ⟶ ADP + DHAP + H+ - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation II:
ATP + dihydroxyacetone ⟶ ADP + DHAP + H+ - superpathway of glycerol degradation to 1,3-propanediol:
ATP + dihydroxyacetone ⟶ ADP + DHAP + H+ - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - formaldehyde assimilation III (dihydroxyacetone cycle):
ATP + dihydroxy-acetone ⟶ ADP + H+ + dihydroxyacetone phosphate - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation to butanol:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation II:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - formaldehyde assimilation III (dihydroxyacetone cycle):
D-xylulose 5-phosphate + formaldehyde ⟶ D-glyceraldehyde 3-phosphate + dihydroxyacetone - formaldehyde assimilation III (dihydroxyacetone cycle):
3-phospho-D-glycerate + ATP ⟶ 1,3-diphosphateglycerate + ADP + H+ - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation to butanol:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation II:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation to butanol:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation II:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(7)
- glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone - glycerol degradation V:
NAD+ + glycerol ⟶ H+ + NADH + dihydroxyacetone
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PharmGKB(0)
7 个相关的物种来源信息
- 9606 Homo sapiens:
- 4081 Solanum lycopersicum: 10.1038/SDATA.2014.29
- 39510 Agave americana: 10.1038/NPLANTS.2016.178
- 9606 Homo sapiens:
- 4081 Solanum lycopersicum: 10.1038/SDATA.2014.29
- 39510 Agave americana: 10.1038/NPLANTS.2016.178
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ella R P Grierson, Amali H Thrimawithana, John W van Klink, David H Lewis, Ignacio Carvajal, Jason Shiller, Poppy Miller, Simon C Deroles, Michael J Clearwater, Kevin M Davies, David Chagné, Kathy E Schwinn. A phosphatase gene is linked to nectar dihydroxyacetone accumulation in mānuka (Leptospermum scoparium).
The New phytologist.
2024 Jun; 242(5):2270-2284. doi:
10.1111/nph.19714. [PMID: 38532557] - Maoxiang Zhao, Toshiyuki Nakamura, Yoshimasa Nakamura, Shintaro Munemasa, Izumi C Mori, Yoshiyuki Murata. The effect of exogenous dihydroxyacetone and methylglyoxal on growth, anthocyanin accumulation, and the glyoxalase system in Arabidopsis.
Bioscience, biotechnology, and biochemistry.
2023 Aug; ?(?):. doi:
10.1093/bbb/zbad109. [PMID: 37553179] - Zhen Yuan, Hai Liu, Yimin Wang, Yihu Ke. Biosynthesis of Au/CuO catalyst with Syringa oblata Lindl. leaf extract for efficient selective oxidation of glycerol to 1,3-dihydroxyacetone.
Nanotechnology.
2023 Jun; ?(?):. doi:
10.1088/1361-6528/acdd7c. [PMID: 37307796] - Sylvester A Obeng-Darko, Jean Sloan, Rachel M Binks, Peter R Brooks, Erik J Veneklaas, Patrick M Finnegan. Dihydroxyacetone in the Floral Nectar of Ericomyrtus serpyllifolia (Turcz.) Rye (Myrtaceae) and Verticordia chrysantha Endl. (Myrtaceae) Demonstrates That This Precursor to Bioactive Honey Is Not Restricted to the Genus Leptospermum (Myrtaceae).
Journal of agricultural and food chemistry.
2023 May; 71(20):7703-7709. doi:
10.1021/acs.jafc.3c00673. [PMID: 37191313] - Igor Rafael Sousa Costa, Francisco Lucas Pacheco Cavalcante, Fábio Rossi Cavalcanti, Cleberson de Freitas Fernandes, Enéas Gomes-Filho, Kirley Marques Canuto, Humberto Henrique de Carvalho. Metabolomic exhibits different profiles and potential biomarkers of Vitis sp co-cultivated with Fusarium oxysporum for short, medium, and long times.
Physiologia plantarum.
2023 Apr; ?(?):e13918. doi:
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Plant science : an international journal of experimental plant biology.
2022 Oct; 323(?):111378. doi:
10.1016/j.plantsci.2022.111378. [PMID: 35842059] - Juan Matías Viecenz, Patricia Andrea Garavaglia, Laura Mónica Tasso, Cristina Graciela Maidana, Joaquín Juan Bautista Cannata, Gabriela Andrea García. Identification and biochemical characterization of an ATP-dependent dihydroxyacetone kinase from Trypanosoma cruzi.
Experimental parasitology.
2021 Dec; 231(?):108178. doi:
10.1016/j.exppara.2021.108178. [PMID: 34767777] - Michael J Clearwater, Stevie T Noe, Merilyn Manley-Harris, Georgia-Leigh Truman, Stephen Gardyne, Jessica Murray, Sylvester A Obeng-Darko, Sarah J Richardson. Nectary photosynthesis contributes to the production of mānuka (Leptospermum scoparium) floral nectar.
The New phytologist.
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Journal of controlled release : official journal of the Controlled Release Society.
2021 02; 330(?):1071-1079. doi:
10.1016/j.jconrel.2020.11.012. [PMID: 33188826] - David M Perrin. A hypothesis for examining dihydroxyacetone, the active component in sunless tanning products, as a topical prophylactic against SARS-COV-2 transmission.
Medical hypotheses.
2020 Nov; 144(?):110280. doi:
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Nature metabolism.
2020 09; 2(9):893-901. doi:
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PloS one.
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Nature medicine.
2018 09; 24(9):1384-1394. doi:
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Annals of botany.
2018 03; 121(3):501-512. doi:
10.1093/aob/mcx183. [PMID: 29300875] - Michael Hellwig, Jana Rückriemen, Daniel Sandner, Thomas Henle. Unique Pattern of Protein-Bound Maillard Reaction Products in Manuka (Leptospermum scoparium) Honey.
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2017 May; 65(17):3532-3540. doi:
10.1021/acs.jafc.7b00797. [PMID: 28415841] - Irene Marco-Rius, Peng Cao, Cornelius von Morze, Matthew Merritt, Karlos X Moreno, Gene-Yuan Chang, Michael A Ohliger, David Pearce, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron. Multiband spectral-spatial RF excitation for hyperpolarized [2-13 C]dihydroxyacetone 13 C-MR metabolism studies.
Magnetic resonance in medicine.
2017 04; 77(4):1419-1428. doi:
10.1002/mrm.26226. [PMID: 27017966] - Irene Marco-Rius, Cornelius von Morze, Renuka Sriram, Peng Cao, Gene-Yuan Chang, Eugene Milshteyn, Robert A Bok, Michael A Ohliger, David Pearce, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron, Matthew Merritt. Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone.
Magnetic resonance in medicine.
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2016 Nov; 26(11):1908-1917. doi:
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Genes & development.
2015 Sep; 29(18):1903-14. doi:
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Journal of agricultural and food chemistry.
2015 Jul; 63(29):6513-7. doi:
10.1021/acs.jafc.5b01930. [PMID: 26140295] - Simon Williams, Jessica King, Maria Revell, Merilyn Manley-Harris, Megan Balks, Franziska Janusch, Michael Kiefer, Michael Clearwater, Peter Brooks, Murray Dawson. Regional, annual, and individual variations in the dihydroxyacetone content of the nectar of ma̅nuka (Leptospermum scoparium) in New Zealand.
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2014 Oct; 62(42):10332-40. doi:
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Plant, cell & environment.
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Diabetology & metabolic syndrome.
2012 Apr; 4(?):12. doi:
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Obesity surgery.
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Stem cell research & therapy.
2012 Feb; 3(1):6. doi:
10.1186/scrt97. [PMID: 22333342] - Marie-Françoise Ritz, Caspar Grond-Ginsbach, Stefan Engelter, Philippe Lyrer. Gene expression suggests spontaneously hypertensive rats may have altered metabolism and reduced hypoxic tolerance.
Current neurovascular research.
2012 Feb; 9(1):10-9. doi:
10.2174/156720212799297074. [PMID: 22272763] - Simon J Finney, Susannah K Leaver, Timothy W Evans, Anne Burke-Gaffney. Differences in lipopolysaccharide- and lipoteichoic acid-induced cytokine/chemokine expression.
Intensive care medicine.
2012 Feb; 38(2):324-32. doi:
10.1007/s00134-011-2444-5. [PMID: 22183712] - Tsz-Shan Kam, Cho-Yee Wong, Pui-Long Kwan, Wing Fat-Yiu, Sin-Ming Chiu, Shun-Wan Chan, Kit-San Yuen, Robbie Chan. Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats.
Journal of medicinal food.
2012 Feb; 15(2):190-9. doi:
10.1089/jmf.2011.1625. [PMID: 22273152] - Djédoux Maxime Angaman, Rocco Petrizzo, Francesc Hernández-Gras, Carmen Romero-Segura, Irene Pateraki, Montserrat Busquets, Albert Boronat. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts.
Plant methods.
2012 Jan; 8(1):1. doi:
10.1186/1746-4811-8-1. [PMID: 22243738] - Champika Seneviratne, G W Dombi, W Liu, J A Dain. In vitro glycation of human serum albumin by dihydroxyacetone and dihydroxyacetone phosphate.
Biochemical and biophysical research communications.
2012 Jan; 417(2):817-23. doi:
10.1016/j.bbrc.2011.12.043. [PMID: 22198436] - Marina Quartu, Maria P Serra, Marianna Boi, Giuliano Pillolla, Tiziana Melis, Laura Poddighe, Marina Del Fiacco, Danilo Falconieri, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Antonio Piras, Maria Collu, Sebastiano Banni. Effect of acute administration of Pistacia lentiscus L. essential oil on rat cerebral cortex following transient bilateral common carotid artery occlusion.
Lipids in health and disease.
2012 Jan; 11(?):8. doi:
10.1186/1476-511x-11-8. [PMID: 22239952] - Patrick M Finnegan, Weihua Chen. Arsenic toxicity: the effects on plant metabolism.
Frontiers in physiology.
2012; 3(?):182. doi:
10.3389/fphys.2012.00182. [PMID: 22685440] - Muthenna Puppala, Jessica Ponder, Palla Suryanarayana, Geereddy Bhanuprakash Reddy, J Mark Petrash, Daniel V LaBarbera. The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblica officinalis.
PloS one.
2012; 7(4):e31399. doi:
10.1371/journal.pone.0031399. [PMID: 22485126] - Euan J Rodger, Rachel J Suetani, Gregory T Jones, Torsten Kleffmann, Alan Carne, Michael Legge, Sally P A McCormick. Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis.
PloS one.
2012; 7(1):e30383. doi:
10.1371/journal.pone.0030383. [PMID: 22276189] - Jessica N Lange, Kyle D Wood, John Knight, Dean G Assimos, Ross P Holmes. Glyoxal formation and its role in endogenous oxalate synthesis.
Advances in urology.
2012; 2012(?):819202. doi:
10.1155/2012/819202. [PMID: 22567004] - Gideon Hen, Sara Yosefi, Dmitry Shinder, Adi Or, Sivan Mygdal, Reba Condiotti, Eithan Galun, Amir Bor, Dalit Sela-Donenfeld, Miriam Friedman-Einat. Gene transfer to chicks using lentiviral vectors administered via the embryonic chorioallantoic membrane.
PloS one.
2012; 7(5):e36531. doi:
10.1371/journal.pone.0036531. [PMID: 22606269] - Kazunori Shimizu, Shigeru Kawakami, Kouji Hayashi, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Mitsuru Hashida, Satoshi Konishi. In vivo site-specific transfection of naked plasmid DNA and siRNAs in mice by using a tissue suction device.
PloS one.
2012; 7(7):e41319. doi:
10.1371/journal.pone.0041319. [PMID: 22844458] - Heather M Fritz, Paul W Bowyer, Matthew Bogyo, Patricia A Conrad, John C Boothroyd. Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance.
PloS one.
2012; 7(1):e29955. doi:
10.1371/journal.pone.0029955. [PMID: 22279555] - Valeria R Mas, Kellie J Archer, Catherine I Dumur, Mariano J Scian, Jihee L Suh, Anne L King, Megan E Wardius, Julie A Straub, Marc P Posner, Kenneth Brayman, Daniel G Maluf. Reduced expression of inflammatory genes in deceased donor kidneys undergoing pulsatile pump preservation.
PloS one.
2012; 7(4):e35526. doi:
10.1371/journal.pone.0035526. [PMID: 22545113] - Fotini Kostopoulou, Vasiliki Gkretsi, Konstantinos N Malizos, Dimitrios Iliopoulos, Pagona Oikonomou, Lazaros Poultsides, Aspasia Tsezou. Central role of SREBP-2 in the pathogenesis of osteoarthritis.
PloS one.
2012; 7(5):e35753. doi:
10.1371/journal.pone.0035753. [PMID: 22662110] - Tamara R Castañeda, William Abplanalp, Sung Hee Um, Paul T Pfluger, Brigitte Schrott, Kimberly Brown, Erin Grant, Larissa Carnevalli, Stephen C Benoit, Donald A Morgan, Dean Gilham, David Y Hui, Kamal Rahmouni, George Thomas, Sara C Kozma, Deborah J Clegg, Matthias H Tschöp. Metabolic control by S6 kinases depends on dietary lipids.
PloS one.
2012; 7(3):e32631. doi:
10.1371/journal.pone.0032631. [PMID: 22412899] - Wei Guo, Li-fang Zou, Yu-rong Li, Yi-ping Cui, Zhi-yuan Ji, Lu-lu Cai, Hua-song Zou, William C Hutchins, Ching-hong Yang, Gong-you Chen. Fructose-bisphophate aldolase exhibits functional roles between carbon metabolism and the hrp system in rice pathogen Xanthomonas oryzae pv. oryzicola.
PloS one.
2012; 7(2):e31855. doi:
10.1371/journal.pone.0031855. [PMID: 22384086] - Thérèse Keravis, Fanny Monneaux, Issaka Yougbaré, Lucien Gazi, Jean-Jacques Bourguignon, Sylviane Muller, Claire Lugnier. Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor.
PloS one.
2012; 7(1):e28899. doi:
10.1371/journal.pone.0028899. [PMID: 22247763] - Harriet C T Groom, Anne Y Warren, David E Neal, Kate N Bishop. No evidence for infection of UK prostate cancer patients with XMRV, BK virus, Trichomonas vaginalis or human papilloma viruses.
PloS one.
2012; 7(3):e34221. doi:
10.1371/journal.pone.0034221. [PMID: 22470540] - Young-Man Kim, Sung-Eun Lee, Byeoung-Soo Park, Mi-Kyung Son, Young-Mi Jung, Seung-Ok Yang, Hyung-Kyoon Choi, Sung-Ho Hur, Jong Hwa Yum. Proteomic analysis on acetate metabolism in Citrobacter sp. BL-4.
International journal of biological sciences.
2012; 8(1):66-78. doi:
10.7150/ijbs.8.66. [PMID: 22211106] - Hiroyuki Hirai, Nobuko Katoku-Kikyo, Peter Karian, Meri Firpo, Nobuaki Kikyo. Efficient iPS cell production with the MyoD transactivation domain in serum-free culture.
PloS one.
2012; 7(3):e34149. doi:
10.1371/journal.pone.0034149. [PMID: 22479546] - Christopher A Lopez, Sebastian E Winter, Fabian Rivera-Chávez, Mariana N Xavier, Victor Poon, Sean-Paul Nuccio, Renée M Tsolis, Andreas J Bäumler. Phage-mediated acquisition of a type III secreted effector protein boosts growth of salmonella by nitrate respiration.
mBio.
2012; 3(3):. doi:
10.1128/mbio.00143-12. [PMID: 22691391] - Hervé Colinet, David Renault, Blandine Charoy-Guével, Emmanuelle Com. Metabolic and proteomic profiling of diapause in the aphid parasitoid Praon volucre.
PloS one.
2012; 7(2):e32606. doi:
10.1371/journal.pone.0032606. [PMID: 22389713] - Aurélie Faty, Pascal Ferré, Stéphane Commans. The acute phase protein Serum Amyloid A induces lipolysis and inflammation in human adipocytes through distinct pathways.
PloS one.
2012; 7(4):e34031. doi:
10.1371/journal.pone.0034031. [PMID: 22532826] - Liezel M Gouws, Eileen Botes, Anna J Wiese, Sandra Trenkamp, Ivone Torres-Jerez, Yuhong Tang, Paul N Hills, Björn Usadel, James R Lloyd, Alisdair R Fernie, Jens Kossmann, Margaretha J van der Merwe. The plant growth promoting substance, lumichrome, mimics starch, and ethylene-associated symbiotic responses in lotus and tomato roots.
Frontiers in plant science.
2012; 3(?):120. doi:
10.3389/fpls.2012.00120. [PMID: 22701462] - Jong-Jer Lee, Chang-Chun Hsiao, I-Hui Yang, Ming-Huei Chou, Chia-Lin Wu, Yin-Chu Wei, Chih-Hsin Chen, Jiin-Haur Chuang. High-mobility group box 1 protein is implicated in advanced glycation end products-induced vascular endothelial growth factor A production in the rat retinal ganglion cell line RGC-5.
Molecular vision.
2012; 18(?):838-50. doi:
NULL. [PMID: 22511847] - Aihong Lin, Yiqin Wang, Jiuyou Tang, Peng Xue, Chunlai Li, Linchuan Liu, Bin Hu, Fuquan Yang, Gary J Loake, Chengcai Chu. Nitric oxide and protein S-nitrosylation are integral to hydrogen peroxide-induced leaf cell death in rice.
Plant physiology.
2012 Jan; 158(1):451-64. doi:
10.1104/pp.111.184531. [PMID: 22106097] - Takeo Iwata, Hisaaki Taniguchi, Masamichi Kuwajima, Takako Taniguchi, Yuko Okuda, Akiko Sukeno, Kyoko Ishimoto, Noriko Mizusawa, Katsuhiko Yoshimoto. The action of D-dopachrome tautomerase as an adipokine in adipocyte lipid metabolism.
PloS one.
2012; 7(3):e33402. doi:
10.1371/journal.pone.0033402. [PMID: 22428043] - Atsushi Hosomi, Takeo Nakanishi, Takuya Fujita, Ikumi Tamai. Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2.
PloS one.
2012; 7(2):e30456. doi:
10.1371/journal.pone.0030456. [PMID: 22348008] - Yoichi Shimoda, Junkyu Han, Kiyokazu Kawada, Abderrazak Smaoui, Hiroko Isoda. Metabolomics analysis of Cistus monspeliensis leaf extract on energy metabolism activation in human intestinal cells.
Journal of biomedicine & biotechnology.
2012; 2012(?):428514. doi:
10.1155/2012/428514. [PMID: 22523469] - Adnan M Bakar, Sang Won Park, Mihwa Kim, H Thomas Lee. Isoflurane protects against human endothelial cell apoptosis by inducing sphingosine kinase-1 via ERK MAPK.
International journal of molecular sciences.
2012; 13(1):977-93. doi:
10.3390/ijms13010977. [PMID: 22312298] - Hai Wang, Shengbing Wang, Yuqing Lu, Sophie Alvarez, Leslie M Hicks, Xiaochun Ge, Yiji Xia. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis.
Journal of proteome research.
2012 Jan; 11(1):412-24. doi:
10.1021/pr200918f. [PMID: 22050424] - Kunal Singh, Shadab Nizam, Manisha Sinha, Praveen K Verma. Comparative transcriptome analysis of the necrotrophic fungus Ascochyta rabiei during oxidative stress: insight for fungal survival in the host plant.
PloS one.
2012; 7(3):e33128. doi:
10.1371/journal.pone.0033128. [PMID: 22427966] - Marta Moya, Marta Benet, Carla Guzmán, Laia Tolosa, Carmelo García-Monzón, Eugenia Pareja, José Vicente Castell, Ramiro Jover. Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver.
PloS one.
2012; 7(1):e30014. doi:
10.1371/journal.pone.0030014. [PMID: 22238690] - Marc Galland, Dominique Job, Loïc Rajjou. The seed proteome web portal.
Frontiers in plant science.
2012; 3(?):98. doi:
10.3389/fpls.2012.00098. [PMID: 22701460] - Janelle N Fawver, Hayley E Schall, Rachel D Petrofes Chapa, Xiongwei Zhu, Ian V J Murray. Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding.
Journal of Alzheimer's disease : JAD.
2012; 30(1):63-73. doi:
10.3233/jad-2012-112114. [PMID: 22406446] - Knatokie M Ford, Patricia A D'Amore. Molecular regulation of vascular endothelial growth factor expression in the retinal pigment epithelium.
Molecular vision.
2012; 18(?):519-27. doi:
NULL. [PMID: 22419845] - Senthilkumar Palaniyandi, Arindam Mitra, Christopher D Herren, C Virginia Lockatell, David E Johnson, Xiaoping Zhu, Suman Mukhopadhyay. BarA-UvrY two-component system regulates virulence of uropathogenic E. coli CFT073.
PloS one.
2012; 7(2):e31348. doi:
10.1371/journal.pone.0031348. [PMID: 22363626] - Yu-Huei Liu, Meng-Luen Li, Meng-Yu Hsu, Ya-Yueh Pang, I-Ling Chen, Ching-Kuei Chen, Sai-Wen Tang, Hsuan-Yuan Lin, Jung-Yaw Lin. Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis.
Evidence-based complementary and alternative medicine : eCAM.
2012; 2012(?):935860. doi:
10.1155/2012/935860. [PMID: 22028734] - Vivian Chen, Richard E Staub, Sylvia Fong, Mary Tagliaferri, Isaac Cohen, Emma Shtivelman. Bezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOS.
PloS one.
2012; 7(2):e30300. doi:
10.1371/journal.pone.0030300. [PMID: 22319564] - Xiumin Fu, Wenbin Kong, Gang Peng, Jingyi Zhou, Muhammad Azam, Changjie Xu, Don Grierson, Kunsong Chen. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits.
Journal of experimental botany.
2012 Jan; 63(1):341-54. doi:
10.1093/jxb/err284. [PMID: 21994170] - Chuang Wang, Ying Pan, Qing-Yu Zhang, Fu-Meng Wang, Ling-Dong Kong. Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation.
PloS one.
2012; 7(6):e38285. doi:
10.1371/journal.pone.0038285. [PMID: 22701621] - Gabor Gyetvai, Mads Sønderkær, Ulrike Göbel, Rico Basekow, Agim Ballvora, Maren Imhoff, Birgit Kersten, Kåre-Lehman Nielsen, Christiane Gebhardt. The transcriptome of compatible and incompatible interactions of potato (Solanum tuberosum) with Phytophthora infestans revealed by DeepSAGE analysis.
PloS one.
2012; 7(2):e31526. doi:
10.1371/journal.pone.0031526. [PMID: 22328937] - Xianmei Meng, David J Baylink, Matilda Sheng, Hongjie Wang, Daila S Gridley, K-H William Lau, Xiao-Bing Zhang. Erythroid promoter confines FGF2 expression to the marrow after hematopoietic stem cell gene therapy and leads to enhanced endosteal bone formation.
PloS one.
2012; 7(5):e37569. doi:
10.1371/journal.pone.0037569. [PMID: 22629419] - Lena Hauberg-Lotte, Hannah Klingenberg, Christian Scharf, Melanie Böhm, Jörg Plessl, Frauke Friedrich, Uwe Völker, Anke Becker, Barbara Reinhold-Hurek. Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72.
PloS one.
2012; 7(1):e30421. doi:
10.1371/journal.pone.0030421. [PMID: 22276194] - Jung Pyo Lee, Seung Hee Yang, Hee-Yoon Lee, Bora Kim, Joo-Youn Cho, Jin Ho Paik, Yun Jung Oh, Dong Ki Kim, Chun Soo Lim, Yon Su Kim. Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.
PloS one.
2012; 7(5):e37075. doi:
10.1371/journal.pone.0037075. [PMID: 22590647] - Yuri L Dorokhov, Tatiana V Komarova, Igor V Petrunia, Vyacheslav S Kosorukov, Roman A Zinovkin, Anastasia V Shindyapina, Olga Y Frolova, Yuri Y Gleba. Methanol may function as a cross-kingdom signal.
PloS one.
2012; 7(4):e36122. doi:
10.1371/journal.pone.0036122. [PMID: 22563443] - Tatsuya Uebi, Yumi Itoh, Osamu Hatano, Ayako Kumagai, Masato Sanosaka, Tsutomu Sasaki, Satoru Sasagawa, Junko Doi, Keita Tatsumi, Kuniko Mitamura, Eiichi Morii, Katsuyuki Aozasa, Tomohiro Kawamura, Meinoshin Okumura, Jun Nakae, Hajime Takikawa, Toshio Fukusato, Minako Koura, Mayumi Nish, Anders Hamsten, Angela Silveira, Alejandro M Bertorello, Kazuo Kitagawa, Yasuo Nagaoka, Hidehisa Kawahara, Takeshi Tomonaga, Tetsuji Naka, Shigeo Ikegawa, Noriyuki Tsumaki, Junichiro Matsuda, Hiroshi Takemori. Involvement of SIK3 in glucose and lipid homeostasis in mice.
PloS one.
2012; 7(5):e37803. doi:
10.1371/journal.pone.0037803. [PMID: 22662228] - Yanhua Zheng, Jinbo Li, Xuanyong Liu, Jiao Sun. Antimicrobial and osteogenic effect of Ag-implanted titanium with a nanostructured surface.
International journal of nanomedicine.
2012; 7(?):875-84. doi:
10.2147/ijn.s28450. [PMID: 22393287] - Balraj Singh, Karen Tai, Simran Madan, Milan R Raythatha, Amanda M Cady, Megan Braunlin, LaTashia R Irving, Ankur Bajaj, Anthony Lucci. Selection of metastatic breast cancer cells based on adaptability of their metabolic state.
PloS one.
2012; 7(5):e36510. doi:
10.1371/journal.pone.0036510. [PMID: 22570721] - Paduru Yadagiri Reddy, Nappan Veettil Giridharan, Geereddy Bhanuprakash Reddy. Activation of sorbitol pathway in metabolic syndrome and increased susceptibility to cataract in Wistar-Obese rats.
Molecular vision.
2012; 18(?):495-503. doi:
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PloS one.
2012; 7(3):e33991. doi:
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