Zearalanone (BioDeep_00000004176)

   

natural product PANOMIX_OTCML-2023


代谢物信息卡片


(S)-Zearalanone

化学式: C18H24O5 (320.1624)
中文名称: 玉米赤霉酮
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 77.42%

分子结构信息

SMILES: CC1CCCC(=O)CCCCCC2=C(C(=CC(=C2)O)O)C(=O)O1
InChI: InChI=1S/C18H24O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,20-21H,2-9H2,1H3/t12-/m0/s1

描述信息

同义名列表

4 个代谢物同义名

(S)-Zearalanone; Zearalanone; Zanone;ZAN; Zearalanone



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ALB, AR, ESR1, GPER1, LHB, PGR, PRKX, TFPT, TUBB2B
Peripheral membrane protein 3 CAMKV, CYP1B1, ESR1
Endoplasmic reticulum membrane 3 CYP19A1, CYP1B1, GPER1
Mitochondrion membrane 1 GPER1
Nucleus 8 ALB, AR, ESR1, GPER1, PGR, PRKX, TFPT, TUBB2B
cytosol 6 ALB, AR, COMT, ESR1, GPER1, PGR
dendrite 2 COMT, GPER1
mitochondrial membrane 1 GPER1
trans-Golgi network 1 GPER1
centrosome 1 ALB
nucleoplasm 6 AR, ESR1, GPER1, PGR, PRKX, TFPT
Cell membrane 5 CAMKV, COMT, ESR1, GPRC5A, TNF
Cytoplasmic side 1 ESR1
Cell projection, axon 1 GPER1
Multi-pass membrane protein 4 CYP19A1, GPER1, GPRC5A, KCNA3
Golgi apparatus membrane 1 GPER1
Synapse 1 COMT
cell surface 1 TNF
dendritic shaft 1 GPER1
glutamatergic synapse 2 CAMKV, KCNA3
Golgi apparatus 3 ALB, ESR1, GPER1
Golgi membrane 1 GPER1
neuronal cell body 1 TNF
presynaptic membrane 2 GPER1, KCNA3
Lysosome 1 SGSH
plasma membrane 9 AR, CAMKV, COMT, ESR1, GPER1, GPRC5A, KCNA3, PGR, TNF
presynaptic active zone 1 GPER1
Membrane 7 AR, COMT, CYP19A1, CYP1B1, ESR1, GPER1, KCNA3
axon 3 COMT, GPER1, KCNA3
extracellular exosome 4 ALB, COMT, GPRC5A, SGSH
endoplasmic reticulum 3 ALB, CYP19A1, GPER1
extracellular space 5 ALB, CXCL8, GNRH1, LHB, TNF
lysosomal lumen 1 SGSH
perinuclear region of cytoplasm 2 GPER1, KCNA3
Schaffer collateral - CA1 synapse 1 TUBB2B
mitochondrion 2 BCO2, CYP1B1
protein-containing complex 3 ALB, AR, ESR1
intracellular membrane-bounded organelle 4 COMT, CYP1B1, GPER1, GPRC5A
Microsome membrane 2 CYP19A1, CYP1B1
postsynaptic density 1 GPER1
Secreted 3 ALB, CXCL8, LHB
extracellular region 5 ALB, CXCL8, GNRH1, LHB, TNF
mitochondrial outer membrane 1 PGR
hippocampal mossy fiber to CA3 synapse 1 GPER1
mitochondrial matrix 1 BCO2
Extracellular side 1 COMT
anchoring junction 1 ALB
transcription regulator complex 1 ESR1
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 TUBB2B
nucleolus 2 GPER1, GPRC5A
Early endosome 1 GPER1
recycling endosome 2 GPER1, TNF
Single-pass type II membrane protein 2 COMT, TNF
vesicle 1 GPRC5A
postsynaptic membrane 1 KCNA3
Membrane raft 2 KCNA3, TNF
Cytoplasm, cytoskeleton 1 TUBB2B
microtubule 1 TUBB2B
nuclear speck 1 AR
receptor complex 1 GPRC5A
ciliary basal body 1 ALB
chromatin 3 AR, ESR1, PGR
phagocytic cup 1 TNF
mitotic spindle 1 TUBB2B
centriole 1 ALB
spindle pole 1 ALB
actin filament 1 TFPT
blood microparticle 1 ALB
[Isoform 2]: Cell membrane 1 KCNA3
intercellular bridge 1 TUBB2B
nuclear envelope 1 GPER1
Cytoplasmic vesicle membrane 3 CAMKV, GPER1, GPRC5A
Cell projection, dendrite 1 GPER1
euchromatin 1 ESR1
voltage-gated potassium channel complex 1 KCNA3
Golgi lumen 1 LHB
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
axon terminus 1 GPER1
calyx of Held 1 KCNA3
[Isoform 1]: Nucleus 1 ESR1
[Isoform 1]: Cell membrane 1 KCNA3
keratin filament 1 GPER1
dendritic spine head 1 GPER1
Cell projection, dendritic spine membrane 1 GPER1
dendritic spine membrane 1 GPER1
Ino80 complex 1 TFPT
pituitary gonadotropin complex 1 LHB
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform 4]: Mitochondrion outer membrane 1 PGR
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
[Isoform 3]: Cytoplasm, perinuclear region 1 KCNA3
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Thomas J Turbyville, E M Kithsiri Wijeratne, Manping X Liu, Anna M Burns, Christopher J Seliga, Libia A Luevano, Cynthia L David, Stanley H Faeth, Luke Whitesell, A A Leslie Gunatilaka. Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert. Journal of natural products. 2006 Feb; 69(2):178-84. doi: 10.1021/np058095b. [PMID: 16499313]
  • G G Kuiper, J G Lemmen, B Carlsson, J C Corton, S H Safe, P T van der Saag, B van der Burg, J A Gustafsson. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology. 1998 Oct; 139(10):4252-63. doi: 10.1210/endo.139.10.6216. [PMID: 9751507]