Anserine (BioDeep_00000405213)
Main id: BioDeep_00000001659
natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
L-Anserine
化学式: C10H16N4O3 (240.12223459999998)
中文名称: L-鹅肌肽, 鹅肌肽
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C=NC=C1CC(C(=O)O)NC(=O)CCN
InChI: InChI=1S/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1
描述信息
A dipeptide comprising of beta-alanine and 3-methyl-L-histidine units.
C26170 - Protective Agent > C275 - Antioxidant
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
同义名列表
2 个代谢物同义名
数据库引用编号
27 个数据库交叉引用编号
- ChEBI: CHEBI:18323
- KEGG: C01262
- PubChem: 112072
- ChEMBL: CHEMBL448301
- MeSH: Anserine
- CAS: 584-85-0
- MoNA: CCMSLIB00005464329
- MoNA: CCMSLIB00005464483
- MoNA: MoNA024039
- MoNA: MoNA023986
- MoNA: MoNA016939
- MoNA: FiehnHILIC002594
- MoNA: FiehnHILIC001768
- MoNA: FiehnHILIC001069
- MoNA: FiehnHILIC000195
- MoNA: HMDB0000194_ms_ms_313
- MoNA: HMDB0000194_ms_ms_315
- MoNA: HMDB0000194_ms_ms_314
- MetaboLights: MTBLC18323
- PubChem: 4481
- PDB-CCD: 8V3
- 3DMET: B01426
- NIKKAJI: J28.566H
- RefMet: Anserine
- medchemexpress: HY-113354
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-345
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-965
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Luo, Ming Chen, Hongwu Ji, Weifeng Su, Wenkui Song, Di Zhang, Weiming Su, Shucheng Liu. Hypolipidemic and Anti-Obesity Effect of Anserine on Mice Orally Administered with High-Fat Diet via Regulating SREBP-1, NLRP3, and UCP-1.
Molecular nutrition & food research.
2024 Mar; 68(6):e2300471. doi:
10.1002/mnfr.202300471. [PMID: 38400696] - Huan Hong, Jianping Sun, Wangwang Lv, Suren Zhang, Lu Xia, Yang Zhou, A Wang, Jingya Lv, Bowen Li, Jing Wu, Shizhang Liu, Caiyun Luo, Zhenhua Zhang, Lili Jiang, Tsechoe Dorji, Shiping Wang. Warming delays but grazing advances leaf senescence of five plant species in an alpine meadow.
The Science of the total environment.
2023 Feb; 858(Pt 2):159858. doi:
10.1016/j.scitotenv.2022.159858. [PMID: 36374756] - Hirofumi Enomoto, Nobuhiro Zaima. Desorption electrospray ionization-mass spectrometry imaging of carnitine and imidazole dipeptides in pork chop tissues.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2023 Feb; 1216(?):123601. doi:
10.1016/j.jchromb.2023.123601. [PMID: 36680959] - Raju Nalvothula, Surekha Challa, Vidyullatha Peddireddy, Ramchander Merugu, M P Pratap Rudra, Abed Alataway, Ahmed Z Dewidar, Hosam O Elansary. Isolation, Molecular Identification and Amino Acid Profiling of Single-Cell-Protein-Producing Phototrophic Bacteria Isolated from Oil-Contaminated Soil Samples.
Molecules (Basel, Switzerland).
2022 Sep; 27(19):. doi:
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Food research international (Ottawa, Ont.).
2022 08; 158(?):111504. doi:
10.1016/j.foodres.2022.111504. [PMID: 35840213] - Chanadda Suwanvichanee, Panpradub Sinpru, Kasarat Promkhun, Satoshi Kubota, Cindy Riou, Wittawat Molee, Jirawat Yongsawatdigul, Kanjana Thumanu, Amonrat Molee. Effects of β-alanine and L-histidine supplementation on carnosine contents in and quality and secondary structure of proteins in slow-growing Korat chicken meat.
Poultry science.
2022 May; 101(5):101776. doi:
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Phytotherapy research : PTR.
2021 Nov; 35(11):6343-6358. doi:
10.1002/ptr.7285. [PMID: 34533242] - Jiaojiao Han, Ziyan Wang, Chenyang Lu, Jun Zhou, Ye Li, Tinghong Ming, Zhen Zhang, Zaijie Jim Wang, Xiurong Su. The gut microbiota mediates the protective effects of anserine supplementation on hyperuricaemia and associated renal inflammation.
Food & function.
2021 Oct; 12(19):9030-9042. doi:
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Amino acids.
2021 Aug; 53(8):1269-1277. doi:
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Scientific reports.
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10.1038/s41598-021-93100-3. [PMID: 34226581] - Ju Cheng, Di Liu, Lixia Zhao, Qianqian Zhao, Xiaoyun Zhang, Bei Wang, Decheng Bai. Potentilla anserine L. polysaccharide inhibits cadmium-induced neurotoxicity by attenuating autophagy.
Neurochemistry international.
2021 07; 147(?):105045. doi:
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2021 Feb; 18(1):15. doi:
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European journal of nutrition.
2021 Feb; 60(1):179-192. doi:
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International journal of molecular sciences.
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Amino acids.
2020 Apr; 52(4):523-542. doi:
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Amino acids.
2020 Mar; 52(3):329-360. doi:
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Molecular nutrition & food research.
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Molecules (Basel, Switzerland).
2019 Sep; 24(17):. doi:
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European journal of clinical nutrition.
2019 05; 73(5):692-702. doi:
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Molecular nutrition & food research.
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Amino acids.
2019 Jan; 51(1):103-114. doi:
10.1007/s00726-018-2663-y. [PMID: 30302566] - Yalin Zhang, Han Su, Juan Zhang, Juan Kong. The Effects of Ginsenosides and Anserine on the Up-Regulation of Renal Aquaporins 1-4 in Hyperuricemic Mice.
The American journal of Chinese medicine.
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International journal of molecular sciences.
2018 Sep; 19(9):. doi:
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The Journal of physiology.
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Poultry science.
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Amino acids.
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Amino acids.
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Journal of strength and conditioning research.
2011 Feb; 25(2):398-405. doi:
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Clinica chimica acta; international journal of clinical chemistry.
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2010 Aug; 13(4):183-8. doi:
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Nutritional neuroscience.
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Amino acids.
2010 Mar; 38(3):847-58. doi:
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