Anserine (BioDeep_00000405213)
Main id: BioDeep_00000001659
natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019
代谢物信息卡片
L-Anserine
化学式: C10H16N4O3 (240.1222)
中文名称: L-鹅肌肽, 鹅肌肽
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN1C=NC=C1CC(C(=O)O)NC(=O)CCN
InChI: InChI=1S/C10H16N4O3/c1-14-6-12-5-7(14)4-8(10(16)17)13-9(15)2-3-11/h5-6,8H,2-4,11H2,1H3,(H,13,15)(H,16,17)/t8-/m0/s1
描述信息
A dipeptide comprising of beta-alanine and 3-methyl-L-histidine units.
C26170 - Protective Agent > C275 - Antioxidant
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
Anserine, a methylated form of Carnosine, is an orally active, natural Histidine-containing dipeptide found in skeletal muscle of vertebrates. Anserine is not cleaved by serum carnosinase and act as biochemical buffers, chelators, antioxidants, and anti-glycation agents. Anserine improves memory functions in Alzheimer's disease (AD)-model mice[1][2].
同义名列表
3 个代谢物同义名
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:18323
- KEGG: C01262
- PubChem: 112072
- ChEMBL: CHEMBL448301
- MeSH: Anserine
- CAS: 584-85-0
- MoNA: CCMSLIB00005464329
- MoNA: CCMSLIB00005464483
- MoNA: MoNA024039
- MoNA: MoNA023986
- MoNA: MoNA016939
- MoNA: FiehnHILIC002594
- MoNA: FiehnHILIC001768
- MoNA: FiehnHILIC001069
- MoNA: FiehnHILIC000195
- MoNA: HMDB0000194_ms_ms_313
- MoNA: HMDB0000194_ms_ms_315
- MoNA: HMDB0000194_ms_ms_314
- MetaboLights: MTBLC18323
- PubChem: 4481
- PDB-CCD: 8V3
- 3DMET: B01426
- NIKKAJI: J28.566H
- RefMet: Anserine
- medchemexpress: HY-113354
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-345
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-965
- KNApSAcK: 18323
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Luo, Ming Chen, Hongwu Ji, Weifeng Su, Wenkui Song, Di Zhang, Weiming Su, Shucheng Liu. Hypolipidemic and Anti-Obesity Effect of Anserine on Mice Orally Administered with High-Fat Diet via Regulating SREBP-1, NLRP3, and UCP-1.
Molecular nutrition & food research.
2024 Mar; 68(6):e2300471. doi:
10.1002/mnfr.202300471. [PMID: 38400696] - Huan Hong, Jianping Sun, Wangwang Lv, Suren Zhang, Lu Xia, Yang Zhou, A Wang, Jingya Lv, Bowen Li, Jing Wu, Shizhang Liu, Caiyun Luo, Zhenhua Zhang, Lili Jiang, Tsechoe Dorji, Shiping Wang. Warming delays but grazing advances leaf senescence of five plant species in an alpine meadow.
The Science of the total environment.
2023 Feb; 858(Pt 2):159858. doi:
10.1016/j.scitotenv.2022.159858. [PMID: 36374756] - Hirofumi Enomoto, Nobuhiro Zaima. Desorption electrospray ionization-mass spectrometry imaging of carnitine and imidazole dipeptides in pork chop tissues.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2023 Feb; 1216(?):123601. doi:
10.1016/j.jchromb.2023.123601. [PMID: 36680959] - Raju Nalvothula, Surekha Challa, Vidyullatha Peddireddy, Ramchander Merugu, M P Pratap Rudra, Abed Alataway, Ahmed Z Dewidar, Hosam O Elansary. Isolation, Molecular Identification and Amino Acid Profiling of Single-Cell-Protein-Producing Phototrophic Bacteria Isolated from Oil-Contaminated Soil Samples.
Molecules (Basel, Switzerland).
2022 Sep; 27(19):. doi:
10.3390/molecules27196265. [PMID: 36234802] - Enrique Pavan, Arvind K Subbaraj, Graham T Eyres, Patrick Silcock, Carolina E Realini. Association of metabolomic and lipidomic data with Chinese and New Zealand consumer clusters showing preferential likings for lamb meat from three production systems.
Food research international (Ottawa, Ont.).
2022 08; 158(?):111504. doi:
10.1016/j.foodres.2022.111504. [PMID: 35840213] - Chanadda Suwanvichanee, Panpradub Sinpru, Kasarat Promkhun, Satoshi Kubota, Cindy Riou, Wittawat Molee, Jirawat Yongsawatdigul, Kanjana Thumanu, Amonrat Molee. Effects of β-alanine and L-histidine supplementation on carnosine contents in and quality and secondary structure of proteins in slow-growing Korat chicken meat.
Poultry science.
2022 May; 101(5):101776. doi:
10.1016/j.psj.2022.101776. [PMID: 35303689] - Luan He, Ning Liu, Kexin Wang, Ling Zhang, Dan Li, Zhixiang Wang, Guoqiang Xu, Yanli Liu, Qiongming Xu. Rosamultin from Potentilla anserine L. exhibits nephroprotection and antioxidant activity by regulating the reactive oxygen species/C/EBP homologous protein signaling pathway.
Phytotherapy research : PTR.
2021 Nov; 35(11):6343-6358. doi:
10.1002/ptr.7285. [PMID: 34533242] - Jiaojiao Han, Ziyan Wang, Chenyang Lu, Jun Zhou, Ye Li, Tinghong Ming, Zhen Zhang, Zaijie Jim Wang, Xiurong Su. The gut microbiota mediates the protective effects of anserine supplementation on hyperuricaemia and associated renal inflammation.
Food & function.
2021 Oct; 12(19):9030-9042. doi:
10.1039/d1fo01884a. [PMID: 34382991] - Inge Everaert, Thibaux Van der Stede, Jan Stautemas, Maxime Hanssens, Cleo van Aanhold, Hans Baelde, Lynn Vanhaecke, Wim Derave. Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice.
Amino acids.
2021 Aug; 53(8):1269-1277. doi:
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Scientific reports.
2021 07; 11(1):13828. doi:
10.1038/s41598-021-93100-3. [PMID: 34226581] - Ju Cheng, Di Liu, Lixia Zhao, Qianqian Zhao, Xiaoyun Zhang, Bei Wang, Decheng Bai. Potentilla anserine L. polysaccharide inhibits cadmium-induced neurotoxicity by attenuating autophagy.
Neurochemistry international.
2021 07; 147(?):105045. doi:
10.1016/j.neuint.2021.105045. [PMID: 33887379] - L Blancquaert, I Everaert, A Baguet, T Bex, S Barbaresi, S de Jager, E Lievens, J Stautemas, S De Smet, G Baron, E Gilardoni, L Regazzoni, G Aldini, W Derave. Acute preexercise supplementation of combined carnosine and anserine enhances initial maximal power of Wingate tests in humans.
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2021 06; 130(6):1868-1878. doi:
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Journal of the International Society of Sports Nutrition.
2021 Feb; 18(1):15. doi:
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European journal of nutrition.
2021 Feb; 60(1):179-192. doi:
10.1007/s00394-020-02230-3. [PMID: 32246262] - Tim Weigand, Florian Colbatzky, Tilman Pfeffer, Sven F Garbade, Kristina Klingbeil, Florian Colbatzky, Michael Becker, Johanna Zemva, Ruben Bulkescher, Robin Schürfeld, Christian Thiel, Nadine Volk, David Reuss, Georg F Hoffmann, Marc Freichel, Markus Hecker, Tanja Poth, Thomas Fleming, Gernot Poschet, Claus P Schmitt, Verena Peters. A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice.
International journal of molecular sciences.
2020 Jul; 21(14):. doi:
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Amino acids.
2020 Apr; 52(4):523-542. doi:
10.1007/s00726-020-02833-4. [PMID: 32162082] - Guoyao Wu. Important roles of dietary taurine, creatine, carnosine, anserine and 4-hydroxyproline in human nutrition and health.
Amino acids.
2020 Mar; 52(3):329-360. doi:
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Molecular nutrition & food research.
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Molecules (Basel, Switzerland).
2019 Sep; 24(17):. doi:
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European journal of clinical nutrition.
2019 05; 73(5):692-702. doi:
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Molecular nutrition & food research.
2019 03; 63(5):e1801094. doi:
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Amino acids.
2019 Jan; 51(1):103-114. doi:
10.1007/s00726-018-2663-y. [PMID: 30302566] - Yalin Zhang, Han Su, Juan Zhang, Juan Kong. The Effects of Ginsenosides and Anserine on the Up-Regulation of Renal Aquaporins 1-4 in Hyperuricemic Mice.
The American journal of Chinese medicine.
2019; 47(5):1133-1147. doi:
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International journal of molecular sciences.
2018 Sep; 19(9):. doi:
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The Journal of physiology.
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Poultry science.
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Amino acids.
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Nutritional neuroscience.
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Amino acids.
2012 Jun; 42(6):2411-6. doi:
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Journal of strength and conditioning research.
2011 Feb; 25(2):398-405. doi:
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Clinica chimica acta; international journal of clinical chemistry.
2011 Jan; 412(3-4):263-7. doi:
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Nutritional neuroscience.
2010 Aug; 13(4):183-8. doi:
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Nutritional neuroscience.
2010 Jun; 13(3):123-8. doi:
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Amino acids.
2010 Mar; 38(3):847-58. doi:
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The FEBS journal.
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Nutritional neuroscience.
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Molecules and cells.
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