Prostaglandin B2 (BioDeep_00000405082)

Main id: BioDeep_00000004024

 

natural product


代谢物信息卡片


15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid

化学式: C20H30O4 (334.214398)
中文名称: 前列腺素 B2
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(/C=C/[C@@H](O)CCCCC)CCC(=O)C=1C/C=C\CCCC(=O)O
InChI: InChI=1S/C20H30O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h4,7,12,14,17,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24)/b7-4-,14-12+/t17-/m0/s1

描述信息

同义名列表

5 个代谢物同义名

Prostaglandin B2; 15S-hydroxy-9-oxo-5Z,8(12),13E-prostatrienoic acid; FA 20:5;O2; PGB2; Eicosanoids_PGB2_C20H30O4



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(5)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lieke C J van den Berk, Bas J H Jansen, Stuart Snowden, Kim G C Siebers-Vermeulen, Christian Gilissen, Gesine Kögler, Carl G Figdor, Craig E Wheelock, Ruurd Torensma. Cord blood mesenchymal stem cells suppress DC-T Cell proliferation via prostaglandin B2. Stem cells and development. 2014 Jul; 23(14):1582-93. doi: 10.1089/scd.2013.0433. [PMID: 24649980]
  • Jeane Silva, Anke Beckedorf, Erhard Bieberich. Osteoblast-derived oxysterol is a migration-inducing factor for human breast cancer cells. The Journal of biological chemistry. 2003 Jul; 278(28):25376-85. doi: 10.1074/jbc.m301233200. [PMID: 12734199]
  • K Büyükgüzel, H Tunaz, S M Putnam, D Stanley. Prostaglandin biosynthesis by midgut tissue isolated from the tobacco hornworm, Manduca sexta. Insect biochemistry and molecular biology. 2002 Apr; 32(4):435-43. doi: 10.1016/s0965-1748(01)00121-7. [PMID: 11886778]
  • N Cattan, D Mary, A Peleraux, B Mari, C Aussel, B Rossi. Prostaglandin B(2) delivers a co-stimulatory signal leading to T cell activation. European cytokine network. 2000 Jun; 11(2):293-9. doi: ". [PMID: 10903809]
  • S Tassin-Moindrot, A Caille, J P Douliez, D Marion, F Vovelle. The wide binding properties of a wheat nonspecific lipid transfer protein. Solution structure of a complex with prostaglandin B2. European journal of biochemistry. 2000 Feb; 267(4):1117-24. doi: 10.1046/j.1432-1327.2000.01109.x. [PMID: 10672021]
  • S Watanabe, T Kobayashi, H Okuyama. Absence of relation between the expression of cyclooxygenase isoforms and the synthesis of prostaglandin E2 in resident and thioglycollate-elicited macrophages in rats. Prostaglandins & other lipid mediators. 1998 May; 56(1):7-18. doi: 10.1016/s0090-6980(98)00039-2. [PMID: 9674017]
  • W S Powell, F Gravelle, S Gravel. Phorbol myristate acetate stimulates the formation of 5-oxo-6,8,11,14-eicosatetraenoic acid by human neutrophils by activating NADPH oxidase. The Journal of biological chemistry. 1994 Oct; 269(41):25373-80. doi: . [PMID: 7929234]
  • S T Ohnishi, A Sakamoto, T Ohnishi, R Ogawa. Inhibition of lipid peroxidation by prostaglandin oligomeric derivatives. Prostaglandins, leukotrienes, and essential fatty acids. 1992 Mar; 45(3):217-21. doi: 10.1016/0952-3278(92)90116-z. [PMID: 1317035]
  • L O Eriksson, B Larsson, H Hedlund, K E Andersson. Prostaglandin E2 binding sites in human renal tissue: characterization and localization by radioligand binding and autoradiography. Acta physiologica Scandinavica. 1990 Jul; 139(3):393-404. doi: 10.1111/j.1748-1716.1990.tb08940.x. [PMID: 2173350]
  • E P Brass, M J Garrity. Structural specificity for prostaglandin effects on hepatocyte glycogenolysis. The Biochemical journal. 1990 Apr; 267(1):59-62. doi: 10.1042/bj2670059. [PMID: 2158311]