Adenylthiomethylpentose (BioDeep_00000399874)

Main id: BioDeep_00000001262

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


NCGC00263645-02_C11H15N5O3S_5-Methylthioadenosine

化学式: C11H15N5O3S (297.089556)
中文名称: 5′-脱氧-5′-(甲硫基)腺苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CSCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
InChI: InChI=1S/C11H15N5O3S/c1-20-2-5-7(17)8(18)11(19-5)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
Adenosine with the hydroxy group at C-5 substituted with a methylthio (methylsulfanyl) group.
COVID info from COVID-19 Disease Map
D004791 - Enzyme Inhibitors
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].
5'-Methylthioadenosine (5'-(Methylthio)-5'-deoxyadenosine) is a nucleoside generated from S-adenosylmethionine (SAM) during polyamine synthesis[1]. 5'-Methylthioadenosine suppresses tumors by inhibiting tumor cell proliferation, invasion, and the induction of apoptosis while controlling the inflammatory micro-environments of tumor tissue. 5'-Methylthioadenosine and its associated materials have striking regulatory effects on tumorigenesis[2].

同义名列表

9 个代谢物同义名

5-Deoxy-5-Methylthioadenosine; 5-S-Methyl-5-thioadenosine; Adenylthiomethylpentose; 5-Methylthioadenosine; NCGC00263645-02_C11H15N5O3S_5-Methylthioadenosine; 5'-(Methylthio)-5'-deoxyadenosine; 5'-Deoxy-5'-(methylthio)adenosine; 5'-S-Methyl-5'-thioadenosine; 5'-Methylthioadenosine



数据库引用编号

22 个数据库交叉引用编号

分类词条

28 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Qiang Lyu, Rou-An Chen, Hsiao-Li Chuang, Hsin-Bai Zou, Lihong Liu, Li-Kang Sung, Po-Yu Liu, Hsin-Yi Wu, Hsin-Yuan Chang, Wan-Ju Cheng, Wei-Kai Wu, Ming-Shiang Wu, Cheng-Chih Hsu. Bifidobacterium alleviate metabolic disorders via converting methionine to 5'-methylthioadenosine. Gut microbes. 2024 Jan; 16(1):2300847. doi: 10.1080/19490976.2023.2300847. [PMID: 38439565]
  • Timothy Salita, Yepy H Rustam, Vinzenz Hofferek, Michael Jackson, Isaac Tollestrup, Jeffrey P Sheridan, Vern L Schramm, Gary B Evans, Gavin E Reid, Andrew B Munkacsi. Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023 Jun; ?(?):159346. doi: 10.1016/j.bbalip.2023.159346. [PMID: 37301365]
  • Justin A North, John A Wildenthal, Tobias J Erb, Bradley S Evans, Kathryn M Byerly, John A Gerlt, Fred R Tabita. A bifunctional salvage pathway for two distinct S-adenosylmethionine by-products that is widespread in bacteria, including pathogenic Escherichia coli. Molecular microbiology. 2020 05; 113(5):923-937. doi: 10.1111/mmi.14459. [PMID: 31950558]
  • Pramod Kumar, Gajanand Sharma, Varun Gupta, Ramanpreet Kaur, Kanika Thakur, Ruchi Malik, Anil Kumar, Naveen Kaushal, Om Prakash Katare, Kaisar Raza. Oral Delivery of Methylthioadenosine to the Brain Employing Solid Lipid Nanoparticles: Pharmacokinetic, Behavioral, and Histopathological Evidences. AAPS PharmSciTech. 2019 Jan; 20(2):74. doi: 10.1208/s12249-019-1296-0. [PMID: 30631981]
  • Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
  • Justin A North, Jaya Sriram, Karuna Chourey, Christopher D Ecker, Ritin Sharma, John A Wildenthal, Robert L Hettich, F Robert Tabita. Metabolic Regulation as a Consequence of Anaerobic 5-Methylthioadenosine Recycling in Rhodospirillum rubrum. mBio. 2016 07; 7(4):. doi: 10.1128/mbio.00855-16. [PMID: 27406564]
  • Zhenggui Du, Yongjie Zhou, Xufeng Lu, Lei Li, Changli Lu, Li Li, Bo Li, Hong Bu, Jiayin Yang, Yujun Shi. Octreotide prevents liver failure through upregulating 5'-methylthioadenosine in extended hepatectomized rats. Liver international : official journal of the International Association for the Study of the Liver. 2016 Feb; 36(2):212-22. doi: 10.1111/liv.12863. [PMID: 25944273]
  • Wolfgang Zierer, Mohammad R Hajirezaei, Kai Eggert, Norbert Sauer, Nicolaus von Wirén, Benjamin Pommerrenig. Phloem-Specific Methionine Recycling Fuels Polyamine Biosynthesis in a Sulfur-Dependent Manner and Promotes Flower and Seed Development. Plant physiology. 2016 Feb; 170(2):790-806. doi: 10.1104/pp.15.00786. [PMID: 26662272]
  • Swati Dey, Justin A North, Jaya Sriram, Bradley S Evans, F Robert Tabita. In Vivo Studies in Rhodospirillum rubrum Indicate That Ribulose-1,5-bisphosphate Carboxylase/Oxygenase (Rubisco) Catalyzes Two Obligatorily Required and Physiologically Significant Reactions for Distinct Carbon and Sulfur Metabolic Pathways. The Journal of biological chemistry. 2015 Dec; 290(52):30658-68. doi: 10.1074/jbc.m115.691295. [PMID: 26511314]
  • Cara L Fiore, Krista Longnecker, Melissa C Kido Soule, Elizabeth B Kujawinski. Release of ecologically relevant metabolites by the cyanobacterium Synechococcus elongates CCMP 1631. Environmental microbiology. 2015 Oct; 17(10):3949-63. doi: 10.1111/1462-2920.12899. [PMID: 25970745]
  • Michael L Barta, Keisha Thomas, Hongling Yuan, Scott Lovell, Kevin P Battaile, Vern L Schramm, P Scott Hefty. Structural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway. The Journal of biological chemistry. 2014 Nov; 289(46):32214-32229. doi: 10.1074/jbc.m114.594325. [PMID: 25253688]
  • Ye Ni Zhang, Min Song, Tzi Bun Ng, Li Zhao, Fang Liu. Purification and characterization of antioxidant components from the fruiting bodies of Pleurotus abalonus including 9-beta-d-ribofuranosidoadenine, 5'-deoxy-5'-(methylthio)adenosine, and a triterpenoid. Environmental toxicology and pharmacology. 2013 Sep; 36(2):689-696. doi: 10.1016/j.etap.2013.06.007. [PMID: 23892470]
  • Ishari Waduwara-Jayabahu, Yasmin Oppermann, Markus Wirtz, Zachary T Hull, Sarah Schoor, Alexander N Plotnikov, Rüdiger Hell, Margret Sauter, Barbara A Moffatt. Recycling of methylthioadenosine is essential for normal vascular development and reproduction in Arabidopsis. Plant physiology. 2012 Apr; 158(4):1728-44. doi: 10.1104/pp.111.191072. [PMID: 22345506]
  • Anita Zamboni, Laura Zanin, Nicola Tomasi, Mario Pezzotti, Roberto Pinton, Zeno Varanini, Stefano Cesco. Genome-wide microarray analysis of tomato roots showed defined responses to iron deficiency. BMC genomics. 2012 Mar; 13(?):101. doi: 10.1186/1471-2164-13-101. [PMID: 22433273]
  • Kenichi Yamazaki, Yoshihiko Ikeguchi, Takuya Niwa, Kaoru Hayashi, Takahiro Iwaki, Ikumi Ishii, Masaru Niitsu, Anthony E Pegg, Akira Shirahata. Determination of cellular aminopropyltransferase activity using precolumn fluorescent etheno-derivatization with high-performance liquid chromatography. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2012; 28(6):621-4. doi: 10.2116/analsci.28.621. [PMID: 22729051]
  • Thanawat Pitakpornpreecha, Anuchit Plubrukarn, Rapepun Wititsuwannakul. Quantification of 5'-deoxy-5'-methylthioadenosine in heat-treated natural rubber latex serum. Phytochemical analysis : PCA. 2012 Jan; 23(1):12-5. doi: 10.1002/pca.1319. [PMID: 21538640]
  • Ewa Bretes, Andrzej Guranowski, Katarzyna Nuc. 5'-methylthioadenosine nucleosidase from yellow lupine (Lupinus luteus): molecular characterization and mutational analysis. Protein and peptide letters. 2011 Aug; 18(8):817-24. doi: 10.2174/092986611795714023. [PMID: 21443501]
  • S Sivapalaratnam, M M Motazacker, S Maiwald, G K Hovingh, J J P Kastelein, M Levi, M D Trip, G M Dallinga-Thie. Genome-wide association studies in atherosclerosis. Current atherosclerosis reports. 2011 Jun; 13(3):225-32. doi: 10.1007/s11883-011-0173-4. [PMID: 21369780]
  • Benjamin Pommerrenig, Kirstin Feussner, Wolfgang Zierer, Valentyna Rabinovych, Franz Klebl, Ivo Feussner, Norbert Sauer. Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis. The Plant cell. 2011 May; 23(5):1904-19. doi: 10.1105/tpc.110.079657. [PMID: 21540433]
  • Wenqiang Pang, Ying Zhang, Shiming Wang, Aiqun Jia, Wei Dong, Chun Cai, Zichun Hua, Jianfa Zhang. The mPlrp2 and mClps genes are involved in the hydrolysis of retinyl esters in the mouse liver. Journal of lipid research. 2011 May; 52(5):934-41. doi: 10.1194/jlr.m010082. [PMID: 21339507]
  • Indranil Basu, Joseph Locker, Maria B Cassera, Thomas J Belbin, Emilio F Merino, Xinyuan Dong, Ivan Hemeon, Gary B Evans, Chandan Guha, Vern L Schramm. Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase. The Journal of biological chemistry. 2011 Feb; 286(6):4902-11. doi: 10.1074/jbc.m110.198374. [PMID: 21135097]
  • Barbara Roe, Elizabeth Kensicki, Robert Mohney, William W Hall. Metabolomic profile of hepatitis C virus-infected hepatocytes. PloS one. 2011; 6(8):e23641. doi: 10.1371/journal.pone.0023641. [PMID: 21853158]
  • Karen K W Siu, Kyle Asmus, Allison N Zhang, Cathy Horvatin, Sheng Li, Tong Liu, Barbara Moffatt, Virgil L Woods, P Lynne Howell. Mechanism of substrate specificity in 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. Journal of structural biology. 2011 Jan; 173(1):86-98. doi: 10.1016/j.jsb.2010.06.006. [PMID: 20554051]
  • Wayne Chadwick, Randall Brenneman, Bronwen Martin, Stuart Maudsley. Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. International journal of Alzheimer's disease. 2010 Dec; 2010(?):604792. doi: 10.4061/2010/604792. [PMID: 21151659]
  • Huawen Lin, Alan L Kwan, Susan K Dutcher. Synthesizing and salvaging NAD: lessons learned from Chlamydomonas reinhardtii. PLoS genetics. 2010 Sep; 6(9):e1001105. doi: 10.1371/journal.pgen.1001105. [PMID: 20838591]
  • Daniel A Enquobahrie, Michelle A Williams, Chunfang Qiu, Seid Y Muhie, Kimberly Slentz-Kesler, Zhaoping Ge, Tanya Sorenson. Early pregnancy peripheral blood gene expression and risk of preterm delivery: a nested case control study. BMC pregnancy and childbirth. 2009 Dec; 9(?):56. doi: 10.1186/1471-2393-9-56. [PMID: 20003277]
  • Laurence Colin, Carine Van Lint. Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies. Retrovirology. 2009 Dec; 6(?):111. doi: 10.1186/1742-4690-6-111. [PMID: 19961595]
  • Yan Zhang, Guiying Zhang, Jiahuan Zhang, Xiaoyu Wang, Jinsheng Wang. Mutagenesis of the enolase-phosphatase gene in Xanthomonas oryzae pv. oryzae affects growth on methylthioadenosine and in vivo S-adenosylmethionine pools. Archives of microbiology. 2009 Oct; 191(10):773-83. doi: 10.1007/s00203-009-0505-8. [PMID: 19730818]
  • Yukihito Kabuyama, Elizabeth S Litman, Paul D Templeton, Sandra I Metzner, Eric S Witze, Gretchen M Argast, Stephen J Langer, Kirsi Polvinen, Yiqun Shellman, Daniel Chan, John B Shabb, James E Fitzpatrick, Katheryn A Resing, Marcelo C Sousa, Natalie G Ahn. A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme. Molecular & cellular proteomics : MCP. 2009 Oct; 8(10):2308-20. doi: 10.1074/mcp.m900178-mcp200. [PMID: 19620624]
  • Hubert Cieśliński, Anna Długołecka, Józef Kur, Marianna Turkiewicz. An MTA phosphorylase gene discovered in the metagenomic library derived from Antarctic top soil during screening for lipolytic active clones confers strong pink fluorescence in the presence of rhodamine B. FEMS microbiology letters. 2009 Oct; 299(2):232-40. doi: 10.1111/j.1574-6968.2009.01756.x. [PMID: 19732148]
  • Karen K W Siu, Jeffrey E Lee, Janice R Sufrin, Barbara A Moffatt, Martin McMillan, Kenneth A Cornell, Chelsea Isom, P Lynne Howell. Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases. Journal of molecular biology. 2008 Apr; 378(1):112-28. doi: 10.1016/j.jmb.2008.01.088. [PMID: 18342331]
  • Ya Zhao, Zhong Yuan. [A new coumarin glycoside from Glehnia littoralis]. Yao xue xue bao = Acta pharmaceutica Sinica. 2007 Oct; 42(10):1070-3. doi: . [PMID: 18229615]
  • Katharina Bürstenbinder, Guillaume Rzewuski, Markus Wirtz, Rüdiger Hell, Margret Sauter. The role of methionine recycling for ethylene synthesis in Arabidopsis. The Plant journal : for cell and molecular biology. 2007 Jan; 49(2):238-49. doi: 10.1111/j.1365-313x.2006.02942.x. [PMID: 17144895]
  • Quanren He, Hirofumi Suzuki, Raghubir P Sharma. S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver. Journal of applied toxicology : JAT. 2006 Nov; 26(6):509-16. doi: 10.1002/jat.1170. [PMID: 17080400]
  • Manas K Chattopadhyay, Celia White Tabor, Herbert Tabor. Methylthioadenosine and polyamine biosynthesis in a Saccharomyces cerevisiae meu1delta mutant. Biochemical and biophysical research communications. 2006 Apr; 343(1):203-7. doi: 10.1016/j.bbrc.2006.02.144. [PMID: 16530730]
  • Natalia Nieto, Arthur I Cederbaum. S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter. The Journal of biological chemistry. 2005 Sep; 280(35):30963-74. doi: 10.1074/jbc.m503569200. [PMID: 15983038]
  • Tomasz Stepkowski, Krzysztof Brzeziński, Andrzej B Legocki, Mariusz Jaskólski, Gilles Béna. Bayesian phylogenetic analysis reveals two-domain topology of S-adenosylhomocysteine hydrolase protein sequences. Molecular phylogenetics and evolution. 2005 Jan; 34(1):15-28. doi: 10.1016/j.ympev.2004.09.008. [PMID: 15579379]
  • Margret Sauter, Kenneth A Cornell, Sára Beszteri, Guillaume Rzewuski. Functional analysis of methylthioribose kinase genes in plants. Plant physiology. 2004 Dec; 136(4):4061-71. doi: 10.1104/pp.104.053587. [PMID: 15557090]
  • Andres A Caro, Arthur I Cederbaum. Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations. Free radical biology & medicine. 2004 May; 36(10):1303-16. doi: 10.1016/j.freeradbiomed.2004.02.015. [PMID: 15110395]
  • Agnieszka Sekowska, Antoine Danchin. The methionine salvage pathway in Bacillus subtilis. BMC microbiology. 2002 Apr; 2(?):8. doi: 10.1186/1471-2180-2-8. [PMID: 12022921]
  • H J Hwang, E H Kim, Y D Cho. Isolation and properties of arginase from a shade plant, ginseng (Panax ginseng C.A. Meyer) roots. Phytochemistry. 2001 Dec; 58(7):1015-24. doi: 10.1016/s0031-9422(01)00392-2. [PMID: 11730864]
  • K A Mowen, J Tang, W Zhu, B T Schurter, K Shuai, H R Herschman, M David. Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell. 2001 Mar; 104(5):731-41. doi: 10.1016/s0092-8674(01)00269-0. [PMID: 11257227]
  • M M Simile, S Banni, E Angioni, G Carta, M R De Miglio, M R Muroni, D F Calvisi, A Carru, R M Pascale, F Feo. 5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication. Journal of hepatology. 2001 Mar; 34(3):386-94. doi: 10.1016/s0168-8278(00)00078-7. [PMID: 11322199]
  • H M Liebich, C Di Stefano, A Wixforth, H R Schmid. Quantitation of urinary nucleosides by high-performance liquid chromatography. Journal of chromatography. A. 1997 Feb; 763(1-2):193-7. doi: 10.1016/s0021-9673(96)00757-1. [PMID: 9129323]
  • L E Brackett, J W Daly. Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts. Biochemical pharmacology. 1994 Mar; 47(5):801-14. doi: 10.1016/0006-2952(94)90480-4. [PMID: 8135856]
  • J Kido, Y Ashida, K Shinkai, H Akedo, A Isoai, H Kumagai, H Inoue. Effects of methylthiodeoxyadenosine and its analogs on in vitro invasion of rat ascites hepatoma cells and methylation of their phospholipids. Japanese journal of cancer research : Gann. 1991 Oct; 82(10):1104-11. doi: 10.1111/j.1349-7006.1991.tb01764.x. [PMID: 1955377]
  • K Kaneko, S Fujimori, T Kumakawa, N Kamatani, I Akaoka. Disturbance in the metabolism of 5'-methylthioadenosine and adenine in patients with neoplastic diseases, and in those with a deficiency in adenine phosphoribosyltransferase. Metabolism: clinical and experimental. 1991 Sep; 40(9):918-21. doi: 10.1016/0026-0495(91)90066-6. [PMID: 1895956]
  • L E Brackett, J W Daly. Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms. The Journal of pharmacology and experimental therapeutics. 1991 Apr; 257(1):205-13. doi: NULL. [PMID: 2019986]
  • R G Liteplo, T J Jurewicz. Serum has a differential effect on DNA replication in a human melanoma cell line cultured in methionine or 5'-deoxy-5'-methylthioadenosine. Biochimica et biophysica acta. 1991 Mar; 1088(3):365-72. doi: 10.1016/0167-4781(91)90126-7. [PMID: 2015299]
  • J G Altin, R A Bradshaw. Production of 1,2-diacylglycerol in PC12 cells by nerve growth factor and basic fibroblast growth factor. Journal of neurochemistry. 1990 May; 54(5):1666-76. doi: 10.1111/j.1471-4159.1990.tb01220.x. [PMID: 2324742]
  • K Kaneko, S Fujimori, T Kanbayashi, Y Miyazawa, T Kumakawa, H Fujii, S Miwa, N Kamatani, I Akaoka. Measurement of 5'-methylthioadenosine in patients with neoplasms. International journal of cancer. 1990 Jan; 45(1):8-11. doi: 10.1002/ijc.2910450103. [PMID: 2298507]
  • T K Smith, L Lindqvist, L Alakuijala, T O Eloranta. Effects of dietary polyamine precursors on the metabolism and tissue concentrations of amino acids in the rat. Annals of nutrition & metabolism. 1989; 33(3):143-52. doi: 10.1159/000177531. [PMID: 2802527]
  • F Della Ragione, A Oliva, V Gragnaniello, M Fioretti, A Fioretti, L F Menna, V Papparella, V Zappia. Chromatographic and radioimmunological methods for the determination of 5'-deoxy-5'-methylthioadenosine in biological fluids. Journal of chromatography. 1988 May; 440(?):141-9. doi: 10.1016/s0021-9673(00)94518-7. [PMID: 3403660]
  • G L Russo, F Della Ragione, R Utili, A Andreana, G Ruggiero, V Zappia. Studies on human serum 5'-deoxy-5'-methylthioadenosine phosphorylase: molecular properties and clinical perspectives. Advances in experimental medicine and biology. 1988; 250(?):229-38. doi: 10.1007/978-1-4684-5637-0_21. [PMID: 3151228]
  • N R Smalheiser, N B Schwartz. Kinetic analysis of 'rapid onset' neurite formation in NG108-15 cells reveals a dual role for substratum-bound laminin. Brain research. 1987 Jul; 431(1):111-21. doi: 10.1016/0165-3806(87)90200-8. [PMID: 3620981]
  • M Näslund, I Kláŝterská, A Kolman, L Ehrenberg. Mutagenic and comutagenic action of 5'-deoxy-5'-(methylthio)adenosine. Mutation research. 1986 Jun; 161(1):1-7. doi: 10.1016/0027-5107(86)90094-1. [PMID: 3517630]
  • G C Mills, J S Mills. Urinary excretion of methylthioadenosine in immunodeficient children. Clinica chimica acta; international journal of clinical chemistry. 1985 Mar; 147(1):15-23. doi: 10.1016/0009-8981(85)90005-1. [PMID: 3987052]
  • G C Mills, F C Schmalstieg, R M Goldblum. Urinary purines and nucleosides in immune deficiencies. Annals of the New York Academy of Sciences. 1985; 451(?):66-77. doi: 10.1111/j.1749-6632.1985.tb27097.x. [PMID: 3865574]
  • V L Chan, H J Ho. Multiple mechanisms of adenosine toxicity in an adenosine sensitive mutant of baby hamster kidney (BHK) cells. Basic life sciences. 1985; 31(?):103-16. doi: 10.1007/978-1-4613-2449-2_6. [PMID: 3994628]
  • R W Wolford, M K Riscoe, L Johnson, A J Ferro, J H Fitchen. Effect of 5'-methylthioadenosine (a naturally occurring nucleoside) on murine hematopoiesis. Experimental hematology. 1984 Dec; 12(11):867-71. doi: . [PMID: 6510486]
  • K Kaneko, S Fujimori, N Kamatani, I Akaoka. 5'-Methylthioadenosine in urine from normal subjects and cancer patients. Biochimica et biophysica acta. 1984 Nov; 802(2):169-74. doi: 10.1016/0304-4165(84)90158-2. [PMID: 6498213]
  • R L Pajula. Kinetic properties of spermine synthase from bovine brain. The Biochemical journal. 1983 Dec; 215(3):669-76. doi: 10.1042/bj2150669. [PMID: 6419729]
  • R Dante, M Arnaud, A Niveleau. Effects of 5'deoxy-5'-methylthioadenosine on the metabolism of S-adenosyl methionine. Biochemical and biophysical research communications. 1983 Jul; 114(1):214-21. doi: 10.1016/0006-291x(83)91615-7. [PMID: 6309166]
  • K C Agarwal, F X Russo, R E Parks. Inhibition of human and rat platelet aggregation by extracts of Mo-er (Auricularia auricula). Thrombosis and haemostasis. 1982 Oct; 48(2):162-5. doi: . [PMID: 6983740]
  • A Raina, K Tuomi, R L Pajula. Inhibition of the synthesis of polyamines and macromolecules by 5'-methylthioadenosine and 5'-alkylthiotubercidins in BHK21 cells. The Biochemical journal. 1982 Jun; 204(3):697-703. doi: 10.1042/bj2040697. [PMID: 6896990]
  • T O Eloranta, K Tuomi, A M Raina. Uptake and utilization of 5'-methylthioadenosine by cultured baby-hamster kidney cells. The Biochemical journal. 1982 Jun; 204(3):803-7. doi: 10.1042/bj2040803. [PMID: 6896991]
  • V Zappia, F Della Ragione, M Porcelli, G Cacciapuoti, M Carteni-Farina. Studies on 5'-methylthioadenosine uptake by human erythrocytes. Medical biology. 1981 Dec; 59(5-6):354-8. doi: . [PMID: 7339300]
  • C H Edwards, W D Wade, M M Freeburne, E G Jones, R E Stacey, L Sherman, C W Seo, G A Edwards. Formation of methionine from alpha-amino-n-butyric acid and 5'-methylthioadenosine in the rat. The Journal of nutrition. 1977 Oct; 107(10):1927-36. doi: 10.1093/jn/107.10.1927. [PMID: 903835]
  • . . . . doi: . [PMID: 9073064]
  • . . . . doi: . [PMID: 20345605]
  • . . . . doi: . [PMID: 19946895]