phenylbutazone (BioDeep_00000398941)
Main id: BioDeep_00000001859
natural product
代谢物信息卡片
"Phenylbutazone (Butazolidin, Butatron)"
化学式: C19H20N2O2 (308.15247)
中文名称: 苯基丁氮酮, 保泰松
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCC(C(=O)1)C(=O)N(c(c3)cccc3)N(c(c2)cccc2)1
InChI: InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3
描述信息
M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use
M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AA - Butylpyrazolidines
A member of the class of pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
数据库引用编号
19 个数据库交叉引用编号
- ChEBI: CHEBI:48574
- KEGG: C07440
- KEGGdrug: D00510
- PubChem: 4781
- DrugBank: DB00812
- MeSH: Phenylbutazone
- CAS: 4297-92-1
- CAS: 50-33-9
- MoNA: WA002521
- MoNA: WA002520
- MoNA: WA002519
- MoNA: WA002518
- MoNA: WA002517
- MoNA: WA002516
- MoNA: CCMSLIB00000078226
- MetaboLights: MTBLC48574
- PubChem: 9644
- PDB-CCD: P1Z
- NIKKAJI: J792G
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
- 3039 Euglena gracilis: 10.3389/FBIOE.2021.662655
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- B Walters, T N Trumble, E Wendt-Hornickle, M Kennedy, Agp Guedes. Effects of cyclooxygenase and soluble epoxide hydrolase inhibitors on apoptosis of cultured primary equine chondrocytes.
Research in veterinary science.
2022 Oct; 147(?):44-49. doi:
10.1016/j.rvsc.2022.04.002. [PMID: 35447388] - Pamela Waller, Izabela Lomnicka, Cam Lucas, Sara Johnson, Levent Dirikolu. The medication violations in racehorses at Louisiana racetracks from 2016 to 2020.
Veterinary medicine and science.
2022 03; 8(2):553-560. doi:
10.1002/vms3.724. [PMID: 34989156] - G van Galen, C Saegerman, S Hyldahl Laursen, S Jacobsen, M Andersson Munk, H Sjöström, S Holm Lindmark, D Verwilghen. Colonic Health in Hospitalized Horses Treated with Non-Steroidal Anti-Inflammatory Drugs - A Preliminary Study.
Journal of equine veterinary science.
2021 06; 101(?):103451. doi:
10.1016/j.jevs.2021.103451. [PMID: 33993934] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Megan Ricord, Frank M Andrews, Francisco J M Yñiguez, Michael Keowen, Frank Garza, Linda Paul, Ann Chapman, Heidi E Banse. Impact of concurrent treatment with omeprazole on phenylbutazone-induced equine gastric ulcer syndrome (EGUS).
Equine veterinary journal.
2021 Mar; 53(2):356-363. doi:
10.1111/evj.13323. [PMID: 32697849] - Heather K Knych, Rick M Arthur, Daniel S McKemie, Russell W Baden, Kelsey Seminoff, Philip H Kass. Pharmacokinetics and anti-inflammatory effects of flunixin meglumine as a sole agent and in combination with phenylbutazone in exercised Thoroughbred horses.
Equine veterinary journal.
2021 Jan; 53(1):102-116. doi:
10.1111/evj.13260. [PMID: 32145701] - G N Voitenko, A A Kalashnikov, N V Kurdil, V L Savytskyi, L A Ustinova, O G Lutsenko. PROSPECTS FOR CREATION OF RADIOPROTECTIVE MEANS BASED ON NATURAL POLYPHENOLS AND POLYSACCHARIDES.
Problemy radiatsiinoi medytsyny ta radiobiolohii.
2020 Dec; 25(?):309-320. doi:
10.33145/2304-8336-2020-25-309-320. [PMID: 33361843] - Shannon E Grady, Timothy B Lescun, George E Moore, Bruce R Cooper, Alec J Davern, Timothy J Brunner, Sandra D Taylor. Ketorolac Is Not More Effective Than Flunixin Meglumine or Phenylbutazone in Reducing Foot Pain in Horses.
Journal of equine veterinary science.
2020 11; 94(?):103204. doi:
10.1016/j.jevs.2020.103204. [PMID: 33077087] - Hana Nevídalová, Lenka Michalcová, Zdeněk Glatz. Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
Journal of separation science.
2020 Nov; 43(22):4225-4233. doi:
10.1002/jssc.202000594. [PMID: 32966669] - Abhinav Sharma, Neha J Pagidipati, Robert M Califf, Darren K McGuire, Jennifer B Green, Dave Demets, Jyothis Thomas George, Hertzel C Gerstein, Todd Hobbs, Rury R Holman, Francesca C Lawson, Lawrence A Leiter, Marc A Pfeffer, Jane Reusch, Jeffrey S Riesmeyer, Matthew T Roe, Yves Rosenberg, Robert Temple, Stephen Wiviott, John McMurray, Christopher Granger. Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
Circulation.
2020 03; 141(10):843-862. doi:
10.1161/circulationaha.119.041022. [PMID: 31992065] - Gergő Dargó, Dávid Bajusz, Kristóf Simon, Judit Müller, György T Balogh. Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
Journal of medicinal chemistry.
2020 02; 63(4):1763-1774. doi:
10.1021/acs.jmedchem.0c00046. [PMID: 31995375] - Małgorzata Maciążek-Jurczyk, Kamil Janas, Jadwiga Pożycka, Agnieszka Szkudlarek, Wojciech Rogóż, Aleksandra Owczarzy, Karolina Kulig. Human Serum Albumin Aggregation/Fibrillation and its Abilities to Drugs Binding.
Molecules (Basel, Switzerland).
2020 Jan; 25(3):. doi:
10.3390/molecules25030618. [PMID: 32023900] - Khairul Azreena Bakar, Shevin Rizal Feroz. A critical view on the analysis of fluorescence quenching data for determining ligand-protein binding affinity.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Dec; 223(?):117337. doi:
10.1016/j.saa.2019.117337. [PMID: 31302564] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Aparna Nerusu, Dinesh Kumar Chinthapalli, Rajagopal Subramanyam. Role of Herborn (K240E) and Milano Slow (D375H) human serum albumin variants towards binding of phenylbutazone and ibuprofen.
International journal of biological macromolecules.
2019 Aug; 134(?):645-652. doi:
10.1016/j.ijbiomac.2019.05.075. [PMID: 31100401] - Heather K Knych, Rick M Arthur, Dan S McKemie, Kelsey Seminoff, Briana Hamamoto-Hardman, Philip H Kass. Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses.
Drug testing and analysis.
2019 Jun; 11(6):792-803. doi:
10.1002/dta.2553. [PMID: 30499176] - Parichart Tesena, Yodying Yingchutrakul, Sittiruk Roytrakul, Tuempong Wongtawan, Kris Angkanaporn. Serum protein expression in Equine Glandular Gastric Disease (EGGD) induced by phenylbutazone.
The Journal of veterinary medical science.
2019 Mar; 81(3):418-424. doi:
10.1292/jvms.18-0679. [PMID: 30674748] - Luiza de Carvalho Bertozo, Ernesto Tavares Neto, Leandro Cristante de Oliveira, Valdecir Farias Ximenes. Oxidative Alteration of Trp-214 and Lys-199 in Human Serum Albumin Increases Binding Affinity with Phenylbutazone: A Combined Experimental and Computational Investigation.
International journal of molecular sciences.
2018 Sep; 19(10):. doi:
10.3390/ijms19102868. [PMID: 30241420] - Kai-Li Zhou, Dong-Qi Pan, Yan-Yue Lou, Jie-Hua Shi. Intermolecular interaction of fosinopril with bovine serum albumin (BSA): The multi-spectroscopic and computational investigation.
Journal of molecular recognition : JMR.
2018 08; 31(8):e2716. doi:
10.1002/jmr.2716. [PMID: 29659061] - Lauren M Richardson, Canaan M Whitfield-Cargile, Noah D Cohen, Ana M Chamoun-Emanuelli, Hannah J Dockery. Effect of selective versus nonselective cyclooxygenase inhibitors on gastric ulceration scores and intestinal inflammation in horses.
Veterinary surgery : VS.
2018 Aug; 47(6):784-791. doi:
10.1111/vsu.12941. [PMID: 30094858] - Tatiana Syrejshchikova, Natalia Smolina, Valentin Kondratyuk, Gennady Dobretsov, Marat Uzbekov. Influence of Antipsychotic Drug Risperidone on Human Serum Albumin Affinity to Organic Anions.
Current drug discovery technologies.
2018; 15(3):263-269. doi:
10.2174/1570163814666171106153639. [PMID: 29110619] - Canaan M Whitfield-Cargile, Ana M Chamoun-Emanuelli, Noah D Cohen, Lauren M Richardson, Nadim J Ajami, Hannah J Dockery. Differential effects of selective and non-selective cyclooxygenase inhibitors on fecal microbiota in adult horses.
PloS one.
2018; 13(8):e0202527. doi:
10.1371/journal.pone.0202527. [PMID: 30138339] - Mahesh Gokara, Vidadala V Narayana, Vineet Sadarangani, Shatabdi Roy Chowdhury, Sreelaxmi Varkala, Dhevalapally B Ramachary, Rajagopal Subramanyam. Unravelling the binding mechanism and protein stability of human serum albumin while interacting with nefopam analogues: a biophysical and insilico approach.
Journal of biomolecular structure & dynamics.
2017 Aug; 35(10):2280-2292. doi:
10.1080/07391102.2016.1216895. [PMID: 27453381] - Joe O Boison, Patricia Dowling, Johanna L Matus, Jana Kinar, Ron Johnson. The Analysis of Phenylbutazone and Its Active Metabolite, Oxyphenbutazone, in Equine Tissues (Muscle, Kidney, and Liver), Urine, and Serum by LC-MS/MS.
Journal of AOAC International.
2017 Jul; 100(4):1110-1122. doi:
10.5740/jaoacint.16-0127. [PMID: 28145218] - Paul Barnes, Terence L Fodey, Wesley G Smyth, Steven R H Crooks. Investigation of the role of environmental contamination in the occurrence of residues of the veterinary drug phenylbutazone in cattle.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.
2017 Apr; 34(4):520-524. doi:
10.1080/19440049.2016.1271143. [PMID: 28140763] - Hiroshi Matsumoto, Fumiyo Saito, Masahiro Takeyoshi. Investigation of the early-response genes in chemical-induced renal carcinogenicity for the prediction of chemical carcinogenicity in rats.
The Journal of toxicological sciences.
2017; 42(2):175-181. doi:
10.2131/jts.42.175. [PMID: 28321044] - Jie Zhou, Xue Li, Xiaoyun Zhu, Jian Sun, Qianqian Qiu, Wenlong Huang, Hai Qian. Phenylbutazone, a New Long-Acting Agent that can Improve the Peptide Pharmacokinetic Based on Serum Albumin as a Drug Carrier.
Chemical biology & drug design.
2016 06; 87(6):936-45. doi:
10.1111/cbdd.12726. [PMID: 26808199] - Joe O Boison, Trisha Dowling, Ron Johnson, Jana Kinar. Analysis of phenylbutazone residues in horse tissues with and without enzyme-hydrolysis by LC-MS/MS.
Drug testing and analysis.
2016 May; 8(5-6):535-8. doi:
10.1002/dta.2020. [PMID: 27443208] - A Szkudlarek, A Sułkowska, M Maciążek-Jurczyk, M Chudzik, J Równicka-Zubik. Effects of non-enzymatic glycation in human serum albumin. Spectroscopic analysis.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2016 Jan; 152(?):645-53. doi:
10.1016/j.saa.2015.01.120. [PMID: 25735846] - Tamsyn Fourie, Duncan Cromarty, Neil Duncan, Kerri Wolter, Vinny Naidoo. The Safety and Pharmacokinetics of Carprofen, Flunixin and Phenylbutazone in the Cape Vulture (Gyps coprotheres) following Oral Exposure.
PloS one.
2015; 10(10):e0141419. doi:
10.1371/journal.pone.0141419. [PMID: 26512724] - Małgorzata Maciążek-Jurczyk. Phenylbutazone and ketoprofen binding to serum albumin. Fluorescence study.
Pharmacological reports : PR.
2014 Oct; 66(5):727-31. doi:
10.1016/j.pharep.2014.03.005. [PMID: 25149974] - JeongWoo Kang, Su-Jeong Park, Hae-Chul Park, Vinayakumar Gedi, ByungJae So, Kwang-Jick Lee. Multiresidue determination of ten nonsteroidal anti-inflammatory drugs in bovine, porcine, and chicken liver tissues by HPLC-MS/MS.
Applied biochemistry and biotechnology.
2014 Sep; 174(1):1-5. doi:
10.1007/s12010-014-1054-4. [PMID: 25069404] - L Kivett, J Taintor, J Wright. Evaluation of the safety of a combination of oral administration of phenylbutazone and firocoxib in horses.
Journal of veterinary pharmacology and therapeutics.
2014 Aug; 37(4):413-6. doi:
10.1111/jvp.12097. [PMID: 24354928] - Sharanne L Raidal, Kris J Hughes, Amanda-Lee Charman, Sharon G Nielsen, Jacqueline K Phillips, Glenys K Noble. Effects of meloxicam and phenylbutazone on renal responses to furosemide, dobutamine, and exercise in horses.
American journal of veterinary research.
2014 Jul; 75(7):668-79. doi:
10.2460/ajvr.75.7.668. [PMID: 24959734] - Mozaffar Asadi, Zahra Asadi, Somaye Barzegar Sadi, Leila Zarei, Fatemeh Moosavi Baigi, Zahra Amirghofran. Synthesis, characterization and the interaction of some new water-soluble metal Schiff base complexes with human serum albumin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2014 Mar; 122(?):118-29. doi:
10.1016/j.saa.2013.10.070. [PMID: 24299984] - Yoko Nishimura, Yuji Morikawa, Chiaki Kondo, Yutaka Tonomura, Ryou Fukushima, Mikinori Torii, Takeki Uehara. Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies.
Journal of applied toxicology : JAT.
2013 Oct; 33(10):1120-30. doi:
10.1002/jat.2867. [PMID: 23558518] - Takeki Uehara, Chiaki Kondo, Yuji Morikawa, Hiroyuki Hanafusa, Seiko Ueda, Yohsuke Minowa, Noriyuki Nakatsu, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Jyoji Yamate, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani. Toxicogenomic biomarkers for renal papillary injury in rats.
Toxicology.
2013 Jan; 303(?):1-8. doi:
10.1016/j.tox.2012.09.012. [PMID: 23142791] - E D'Arcy-Moskwa, G K Noble, L A Weston, R Boston, S L Raidal. Effects of meloxicam and phenylbutazone on equine gastric mucosal permeability.
Journal of veterinary internal medicine.
2012 Nov; 26(6):1494-9. doi:
10.1111/j.1939-1676.2012.01004.x. [PMID: 23083114] - L R Soma, C E Uboh, G M Maylin. The use of phenylbutazone in the horse.
Journal of veterinary pharmacology and therapeutics.
2012 Feb; 35(1):1-12. doi:
10.1111/j.1365-2885.2011.01299.x. [PMID: 21668837] - K Kitamura, M Niinobu, A A Omran, S Takegami, T Kitade. Binding of diuretic antihypertensive bendroflumethiazide to human serum albumin studied by ¹⁹F nuclear magnetic resonance method.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2012 Jan; 45(1-2):195-200. doi:
10.1016/j.ejps.2011.11.010. [PMID: 22115868] - Véronique Gayrard, Nicole Picard-Hagen, Catherine Viguié, Pierre-Louis Toutain. Competitive binding to plasma thyroid hormone transport proteins and thyroid disruption by phenylbutazone used as a probe.
General and comparative endocrinology.
2011 Nov; 174(2):225-31. doi:
10.1016/j.ygcen.2011.09.001. [PMID: 21933675] - J H Foreman, R Ruemmler. Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses.
Equine veterinary journal. Supplement.
2011 Nov; ?(40):12-7. doi:
10.1111/j.2042-3306.2011.00485.x. [PMID: 22082440] - M Maciążek-Jurczyk, A Sułkowska, B Bojko, J Równicka-Zubik, W W Sułkowski. A spectroscopic study of phenylbutazone and aspirin bound to serum albumin in rheumatoid diseases.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2011 Nov; 82(1):181-90. doi:
10.1016/j.saa.2011.07.030. [PMID: 21856214] - Ali Asghar Mozaffari, Amin Derakhshanfar. Evaluation of the brain, renal, and hepatic effects of flunixin meglumine, ketoprofen, and phenylbutazone administration in Iranian fat-tailed sheep.
Tropical animal health and production.
2011 Oct; 43(7):1389-93. doi:
10.1007/s11250-011-9866-5. [PMID: 21503752] - Monica Aleman, Jorge E Nieto, Jamie K Higgins. Ulcerative cystitis associated with phenylbutazone administration in two horses.
Journal of the American Veterinary Medical Association.
2011 Aug; 239(4):499-503. doi:
10.2460/javma.239.4.499. [PMID: 21838588] - Tor Regberg, Charlotta Lindquist, Ake Pilotti, Christel Ellström, Lars Fägerstam, Ann Eckersten, Yasuro Shinohara, Steven L Gallion, Joseph C Hogan. Novel affinity ligands for chromatography using combinatorial chemistry.
Combinatorial chemistry & high throughput screening.
2011 May; 14(4):267-78. doi:
10.2174/138620711795222482. [PMID: 21143179] - Ho Jung Shin, Michio Takeda, Atsushi Enomoto, Masaaki Fujimura, Hiroki Miyazaki, Naohiko Anzai, Hitoshi Endou. Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
Nephrology (Carlton, Vic.).
2011 Feb; 16(2):156-62. doi:
10.1111/j.1440-1797.2010.01368.x. [PMID: 21272127] - David Buttar, Nicola Colclough, Stefan Gerhardt, Philip A MacFaul, Scott D Phillips, Alleyn Plowright, Paul Whittamore, Kin Tam, Klaus Maskos, Stefan Steinbacher, Holger Steuber. A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Bioorganic & medicinal chemistry.
2010 Nov; 18(21):7486-96. doi:
10.1016/j.bmc.2010.08.052. [PMID: 20869876] - A A Mozaffari, A Derakhshanfar, A Alinejad, M Morovati. A comparative study on the adverse effects of flunixin, ketoprofen and phenylbutazone in miniature donkeys: haematological, biochemical and pathological findings.
New Zealand veterinary journal.
2010 Oct; 58(5):224-8. doi:
10.1080/00480169.2010.69295. [PMID: 20927172] - E C Authie, P Garcia, M A Popot, P L Toutain, M Doucet. Effect of an endurance-like exercise on the disposition and detection time of phenylbutazone and dexamethasone in the horse: application to medication control.
Equine veterinary journal.
2010 Apr; 42(3):240-7. doi:
10.1111/j.2042-3306.2010.00029.x. [PMID: 20486981] - Macarena G Sanz, Debra C Sellon, Julie A Cary, Melissa T Hines, Kelly D Farnsworth. Analgesic effects of butorphanol tartrate and phenylbutazone administered alone and in combination in young horses undergoing routine castration.
Journal of the American Veterinary Medical Association.
2009 Nov; 235(10):1194-203. doi:
10.2460/javma.235.10.1194. [PMID: 19912042] - Chiaki Kondo, Yohsuke Minowa, Takeki Uehara, Yasushi Okuno, Noriyuki Nakatsu, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Jyoji Yamate, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani. Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database.
Toxicology.
2009 Nov; 265(1-2):15-26. doi:
10.1016/j.tox.2009.09.003. [PMID: 19761811] - M Maciazek-Jurczyk, A Sułkowska, B Bojko, J Równicka-Zubik, W W Sułkowski. Interaction of phenylbutazone and colchicine in binding to serum albumin in rheumatoid therapy: 1H NMR study.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2009 Sep; 74(1):1-9. doi:
10.1016/j.saa.2009.06.043. [PMID: 19615934] - L Dirikolu, W E Woods, J Boyles, A F Lehner, J D Harkins, M Fisher, D J Schaeffer, T Tobin. Nonsteroidal anti-inflammatory agents and musculoskeletal injuries in Thoroughbred racehorses in Kentucky.
Journal of veterinary pharmacology and therapeutics.
2009 Jun; 32(3):271-9. doi:
10.1111/j.1365-2885.2008.01038.x. [PMID: 19646092] - Tianga Yaya Soro, F Traore, J Sakande. [Analgesic activity of the aqueous extract from Ximenia Americana].
Comptes rendus biologies.
2009 Apr; 332(4):371-7. doi:
10.1016/j.crvi.2008.08.022. [PMID: 19304267] - Youwen You, Cornelius E Uboh, Lawrence R Soma, Fuyu Guan, Xiaoqing Li, Jeffrey A Rudy, Jinwen Chen. Screening, quantification, and confirmation of phenylbutazone and oxyphenbutazone in equine plasma by liquid chromatography-tandem mass spectrometry.
Journal of analytical toxicology.
2009 Jan; 33(1):41-50. doi:
10.1093/jat/33.1.41. [PMID: 19161668] - Rebecca S McConnico, Timothy W Morgan, Cathleen C Williams, Jeremy D Hubert, Rustin M Moore. Pathophysiologic effects of phenylbutazone on the right dorsal colon in horses.
American journal of veterinary research.
2008 Nov; 69(11):1496-505. doi:
10.2460/ajvr.69.11.1496. [PMID: 18980433] - Ursula Bechert, J Mark Christensen, C Nguyen, R Neelkant, E Bendas. Pharmacokinetics of orally administered phenylbutazone in African and Asian elephants (Loxodonta africana and Elephas maximus).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians.
2008 Jun; 39(2):188-200. doi:
10.1638/2007-0139r.1. [PMID: 18634209] - Bernard Uzzan, Dominique Dumont-Fischer, Najiba Lahlou, Hélène Bihan, Marie-Christophe Boissier, Jean-Claude Alvarez, Gérard-Yves Perret, Régis Cohen. Factitious increases in serum testosterone concentrations related to phenylbutazone therapy.
Fundamental & clinical pharmacology.
2008 Apr; 22(2):159-60. doi:
10.1111/j.1472-8206.2007.00564.x. [PMID: 18353110] - Marco Pistolozzi, Carlo Bertucci. Species-dependent stereoselective drug binding to albumin: a circular dichroism study.
Chirality.
2008 Mar; 20(3-4):552-8. doi:
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2004 Apr; 93(4):847-54. doi:
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Immunopharmacology and immunotoxicology.
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