sissotrin (BioDeep_00000398527)

Main id: BioDeep_00000003551

 

natural product PANOMIX_OTCML-2023


代谢物信息卡片


Biochanin a 7-O-beta-D-glucoside

化学式: C22H22O10 (446.1213)
中文名称: 西索特林
谱图信息: 最多检出来源 Homo sapiens(natural_products) 12.61%

分子结构信息

SMILES: COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)OC4C(C(C(C(O4)CO)O)O)O
InChI: InChI=1S/C22H22O10/c1-29-11-4-2-10(3-5-11)13-9-30-15-7-12(6-14(24)17(15)18(13)25)31-22-21(28)20(27)19(26)16(8-23)32-22/h2-7,9,16,19-24,26-28H,8H2,1H3

描述信息

relative retention time with respect to 9-anthracene Carboxylic Acid is 0.909
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.907
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.906

同义名列表

4 个代谢物同义名

sissotrin; Biochanin a 7-O-beta-D-glucoside; Sissotrine; Biochanin A-beta-D-glucoside



数据库引用编号

44 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

58 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 BCL2, CASP3, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, ESR1, PIK3CA, PPP1R13B
Peripheral membrane protein 5 CYP1B1, CYP2B6, CYP2E1, ESR1, GORASP1
Endosome membrane 1 BACE1
Endoplasmic reticulum membrane 11 BCL2, CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4
Nucleus 5 BCL2, CASP3, ESR1, ESR2, PPP1R13B
cytosol 5 BCL2, CASP3, ESR1, PIK3CA, PPP1R13B
dendrite 1 BACE1
trans-Golgi network 1 BACE1
nucleoplasm 4 CASP3, ESR1, ESR2, PPP1R13B
Cell membrane 3 BACE1, ESR1, GP2
Cytoplasmic side 2 ESR1, GORASP1
lamellipodium 1 PIK3CA
Cell projection, axon 1 BACE1
Golgi apparatus membrane 1 GORASP1
cell surface 2 BACE1, GP2
glutamatergic synapse 1 CASP3
Golgi apparatus 3 BACE1, ESR1, GORASP1
Golgi membrane 2 GORASP1, INS
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 2 BACE1, CASP3
synaptic vesicle 1 BACE1
Lysosome 1 BACE1
endosome 2 BACE1, GP2
plasma membrane 8 BACE1, CYP2C19, CYP2C8, CYP2C9, ESR1, GP2, PIK3CA, PPP1R13B
Membrane 7 BACE1, BCL2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1
apical plasma membrane 1 GP2
axon 1 BACE1
extracellular exosome 1 GP2
endoplasmic reticulum 3 BACE1, BCL2, CYP2D6
extracellular space 2 GP2, INS
perinuclear region of cytoplasm 2 PIK3CA, PPP1R13B
intercalated disc 1 PIK3CA
mitochondrion 4 BCL2, CYP1B1, CYP2D6, ESR2
protein-containing complex 2 BCL2, ESR1
intracellular membrane-bounded organelle 11 CYP1A2, CYP1B1, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4, ESR2
Microsome membrane 7 CYP1A2, CYP1B1, CYP2B6, CYP2C9, CYP2D6, CYP2E1, CYP3A4
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 BACE1
Secreted 2 GP2, INS
extracellular region 2 GP2, INS
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 2 BCL2, CYP2D6
mitochondrial outer membrane 1 BCL2
hippocampal mossy fiber to CA3 synapse 1 BACE1
transcription regulator complex 1 ESR1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 GP2
multivesicular body 1 BACE1
Early endosome 1 BACE1
recycling endosome 1 BACE1
Apical cell membrane 1 GP2
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 2 BACE1, GP2
pore complex 1 BCL2
cis-Golgi network 1 GORASP1
Late endosome 1 BACE1
Zymogen granule membrane 1 GP2
chromatin 2 ESR1, ESR2
Golgi apparatus, trans-Golgi network 1 BACE1
Lipid-anchor, GPI-anchor 1 GP2
Endomembrane system 1 BACE1
endosome lumen 1 INS
Cytoplasmic vesicle membrane 1 BACE1
Cell projection, dendrite 1 BACE1
euchromatin 1 ESR1
myelin sheath 1 BCL2
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 BACE1, INS
phosphatidylinositol 3-kinase complex 1 PIK3CA
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 2 GORASP1, INS
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
[Isoform 1]: Nucleus 1 ESR1
cytoplasmic microtubule 1 CYP2A6
death-inducing signaling complex 1 CASP3
BAD-BCL-2 complex 1 BCL2
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
Golgi-associated vesicle lumen 1 BACE1


文献列表

  • Bingrui Liu, Kenneth T Kongstad, Sun Qinglei, Nils T Nyberg, Anna K Jäger, Dan Staerk. Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata. Journal of natural products. 2015 Feb; 78(2):294-300. doi: 10.1021/np5009416. [PMID: 25679337]