naftifine (BioDeep_00000397870)
Main id: BioDeep_00000002468
代谢物信息卡片
化学式: C21H21N (287.16739060000003)
中文名称: 萘替芬
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(CC=CC1=CC=CC=C1)CC2=CC=CC3=CC=CC=C32
InChI: InChI=1S/C21H21N/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20/h2-15H,16-17H2,1H3
描述信息
D - Dermatologicals > D01 - Antifungals for dermatological use > D01A - Antifungals for topical use
D000890 - Anti-Infective Agents > D000935 - Antifungal Agents
C254 - Anti-Infective Agent > C514 - Antifungal Agent
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3581
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Amit Verma, Babajide Olayinka, Alan B Fleischer. An Open-Label, Multi-Center, Multiple-Application Pharmacokinetic Study of Naftifine HCl Gel 2\% in Pediatric Subjects With Tinea Pedis.
Journal of drugs in dermatology : JDD.
2015 Jul; 14(7):686-91. doi:
. [PMID: 26151784] - G C Porretta, R Fioravanti, M Biava, M Artico, A Villa, N Simonetti. Antifungal agents, Part 11. Biphenyl analogues of naftifine: synthesis and antifungal activities.
Archiv der Pharmazie.
1995 Sep; 328(9):667-72. doi:
10.1002/ardp.19953280907. [PMID: 7487424] - B A Solomon, W L Lee, S C Geen, K Suntharalingam, S M Fikrig, A R Shalita. Modification of neutrophil functions by naftifine.
The British journal of dermatology.
1993 Apr; 128(4):393-8. doi:
10.1111/j.1365-2133.1993.tb00197.x. [PMID: 8388234] - P Butty, A Gorenflot, M Mallié, J M Bastide. Low voltage scanning electron microscopy study of naftifine activity on Microsporum canis.
Mycoses.
1992 Nov; 35(11-12):335-42. doi:
10.1111/j.1439-0507.1992.tb00891.x. [PMID: 1302809] - N H Georgopapadakou, B A Dix, S A Smith, J Freudenberger, P T Funke. Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans.
Antimicrobial agents and chemotherapy.
1987 Jan; 31(1):46-51. doi:
10.1128/aac.31.1.46. [PMID: 3551826] - F Schatz, H Haberl. Analytical methods for the determination of naftifine and its metabolites in human plasma and urine.
Arzneimittel-Forschung.
1986 Dec; 36(12):1850-3. doi:
NULL. [PMID: 3566849] - F Schatz, H Haberl, F Battig, D Jobstmann, G Schulz, M Nefzger, R Czok, A Nikiforov. Major routes of naftifine biotransformation in laboratory animals and man.
Arzneimittel-Forschung.
1986 Feb; 36(2):248-55. doi:
NULL. [PMID: 3964331] - N S Ryder, G Seidl, P F Troke. Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans.
Antimicrobial agents and chemotherapy.
1984 Apr; 25(4):483-7. doi:
10.1128/aac.25.4.483. [PMID: 6375557] - J G Meingassner, U B Sleytr. The effects of naftifine on the ultrastructure of Candida parapsilosis: a freeze fracture study.
Sabouraudia.
1982 Sep; 20(3):199-207. doi:
10.1080/00362178285380301. [PMID: 7135143] - J G Meingassner, U Sleytr, G Petranyi. Morphological changes induced by Naftifine, a new antifungal agent, in Trichophyton mentagrophytes.
The Journal of investigative dermatology.
1981 Dec; 77(6):444-51. doi:
10.1111/1523-1747.ep12495814. [PMID: 7310168]