Ceftazidime (BioDeep_00000397837)

Main id: BioDeep_00000003324

 


代谢物信息卡片


Ceftazidime

化学式: C22H22N6O7S2 (546.0991342)
中文名称: 头孢他啶
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C(=O)O)O/N=C(/c1csc(N)n1)\C(=O)N[C@@H]1C(=O)N2C(=C(C[n+]3ccccc3)CS[C@H]12)C(=O)[O-]
InChI: InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1

描述信息

A cephalosporin bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3238

同义名列表

1 个代谢物同义名

Ceftazidime



数据库引用编号

23 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Dongying Li, Yueyi Li, Jingyi Wang, Weifeng Yang, Kaiyu Cui, Renjing Su, Lu Li, Xing Ren, Xianyu Li, Yi Wang. In-depth analysis of the treatment effect and synergistic mechanism of TanReQing injection on clinical multi-drug resistant Pseudomonas aeruginosa. Microbiology spectrum. 2024 Apr; 12(4):e0272623. doi: 10.1128/spectrum.02726-23. [PMID: 38415603]
  • Iñaki Deza-Cruz, María J Vilar, Martina Velasova, Manal AbuOun, Muna F Anjum, Richard P Smith. Antimicrobial resistance of Escherichia coli in the UK: comparison of single vs. pooled samples from healthy pigs. Letters in applied microbiology. 2023 Nov; ?(?):. doi: 10.1093/lambio/ovad123. [PMID: 37942558]
  • Maytham Hussein, Rafah Allobawi, Jinxin Zhao, Heidi Yu, Stephanie L Neville, Jonathan Wilksch, Labell J M Wong, Mark Baker, Christopher A McDevitt, Gauri G Rao, Jian Li, Tony Velkov. Integrated Transcriptomic and Metabolomic Mapping Reveals the Mechanism of Action of Ceftazidime/Avibactam against Pan-Drug-Resistant Klebsiella pneumoniae. ACS infectious diseases. 2023 Oct; ?(?):. doi: 10.1021/acsinfecdis.3c00264. [PMID: 37878861]
  • Murugan Thulasi Meenu, Grace Kaul, Abdul Akhir, Manjulika Shukla, Kokkuvayil Vasu Radhakrishnan, Sidharth Chopra. Developing the Natural Prenylflavone Artocarpin from Artocarpus hirsutus as a Potential Lead Targeting Pathogenic, Multidrug-Resistant Staphylococcus aureus, Persisters and Biofilms with No Detectable Resistance. Journal of natural products. 2022 10; 85(10):2413-2423. doi: 10.1021/acs.jnatprod.2c00621. [PMID: 36222797]
  • Wenliang Feng, Xuebin Jiang, Rujiang Zhang, Zhendong Guo, Daiquan Gao. Diagnosis of an Acinetobacter pittii from a patient in China with a multiplex PCR-based targeted gene sequencing platform of the cerebrospinal fluid: A case report with literature review. Medicine. 2022 Oct; 101(42):e31130. doi: 10.1097/md.0000000000031130. [PMID: 36281177]
  • Muriel Masi, Julia Vergalli, Ishan Ghai, Andrea Barba-Bon, Thérèse Schembri, Werner M Nau, Daniel Lafitte, Mathias Winterhalter, Jean-Marie Pagès. Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane. Communications biology. 2022 10; 5(1):1059. doi: 10.1038/s42003-022-04035-y. [PMID: 36198902]
  • Kaoru Yamabe, Yukio Arakawa, Masaki Shoji, Katsushiro Miyamoto, Takahiro Tsuchiya, Katsuhiko Minoura, Yukihiro Akeda, Kazunori Tomono, Mitsuko Onda. Enhancement of Acinetobacter baumannii biofilm growth by cephem antibiotics via enrichment of protein and extracellular DNA in the biofilm matrices. Journal of applied microbiology. 2022 Sep; 133(3):2002-2013. doi: 10.1111/jam.15712. [PMID: 35818769]
  • Nabih A Baeshen, Abdulaziz O Albeshri, Naseebh N Baeshen, Roba Attar, Alaa Karkashan, Basma Abbas, Thamer A Bouback, Abdullah A Aljaddawi, Mohammed Y Refai, Hayam S Abdelkader, Abdullah Al Tamim, Abdullah Alowaifeer, Firoz Ahmed, Mohammed N Baeshen. In silico screening of some compounds derived from the desert medicinal plant Rhazya stricta for the potential treatment of COVID-19. Scientific reports. 2022 Jul; 12(1):11120. doi: 10.1038/s41598-022-15288-2. [PMID: 35778482]
  • Nikhil Sadashiv Shetty, Arvind Karikal, Sharanya Menon Radhakrishnan. Melioidosis: an unusual diagnosis for deep temporal and masticatory space infection following trauma. BMJ case reports. 2022 Jun; 15(6):. doi: 10.1136/bcr-2022-248866. [PMID: 35732363]
  • Fernando L Gordillo Altamirano, Xenia Kostoulias, Dinesh Subedi, Denis Korneev, Anton Y Peleg, Jeremy J Barr. Phage-antibiotic combination is a superior treatment against Acinetobacter baumannii in a preclinical study. EBioMedicine. 2022 Jun; 80(?):104045. doi: 10.1016/j.ebiom.2022.104045. [PMID: 35537278]
  • Laetissia Amirouche, Alexandra Cerulli-Kanellopoulos, Sébastien Landry, Véronique C LeBlanc, Ghislain Léger. Ceftazidime-Induced Neurotoxicity in an 80-Year-Old Female With Renal Dysfunction: A Case Report. Journal of pharmacy practice. 2022 Jun; 35(3):482-487. doi: 10.1177/0897190021989931. [PMID: 33517818]
  • Petr Tůma, Martin Jaček, Blanka Sommerová, Pavel Dlouhý, Radka Jarošíková, Jitka Husáková, Veronika Wosková, Vladimíra Fejfarová. Monitoring of amoxicilline and ceftazidime in the microdialysate of diabetic foot and serum by capillary electrophoresis with contactless conductivity detection. Electrophoresis. 2022 06; 43(11):1129-1139. doi: 10.1002/elps.202100366. [PMID: 35072285]
  • Elkin V Lemos-Luengas, Sixta Rentería-Valoyes, Paola Cárdenas-Isaza, Jorge A Ramos-Castaneda. In vitro activity of ceftazidime/avibactam against Gram-negative strains in Colombia 2014-2018. Journal of global antimicrobial resistance. 2022 Jun; 29(?):141-146. doi: 10.1016/j.jgar.2022.02.018. [PMID: 35257971]
  • Ben Vaknin, Nancy Bishouty, Amos Adler. Microbiological and clinical changes following the transition to the 2010 revised CLSI breakpoints for extended-spectrum cephalosporin in Enterobacterales. Diagnostic microbiology and infectious disease. 2022 May; 103(1):115654. doi: 10.1016/j.diagmicrobio.2022.115654. [PMID: 35219970]
  • Gabriele Bianco, Matteo Boattini, Sara Comini, Roberto Casale, Marco Iannaccone, Rossana Cavallo, Cristina Costa. Occurrence of multi-carbapenemases producers among carbapenemase-producing Enterobacterales and in vitro activity of combinations including cefiderocol, ceftazidime-avibactam, meropenem-vaborbactam, and aztreonam in the COVID-19 era. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2022 Apr; 41(4):573-580. doi: 10.1007/s10096-022-04408-5. [PMID: 35061145]
  • Cornélie Fanton D'Andon, Patricia Correia, Josselin Rigaill, Benjamin Kably, Sophie Perinel-Ragey, Manon Launay. Ceftazidime dosing in obese patients: is it time for more?. Expert opinion on drug metabolism & toxicology. 2022 Apr; 18(4):277-284. doi: 10.1080/17425255.2022.2080052. [PMID: 35583387]
  • G Bianco, M Boattini, A Bondi, S Comini, T Zaccaria, R Cavallo, C Costa. Outbreak of ceftazidime-avibactam resistant Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae in a COVID-19 intensive care unit, Italy: urgent need for updated diagnostic protocols of surveillance cultures. The Journal of hospital infection. 2022 04; 122(?):217-219. doi: 10.1016/j.jhin.2022.02.001. [PMID: 35139426]
  • Gabriele Arcari, Alessandra Oliva, Federica Sacco, Federica Maria Di Lella, Giammarco Raponi, Dario Tomolillo, Ambrogio Curtolo, Mario Venditti, Alessandra Carattoli. Interplay between Klebsiella pneumoniae producing KPC-31 and KPC-3 under treatment with high dosage meropenem: a case report. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. 2022 Mar; 41(3):495-500. doi: 10.1007/s10096-021-04388-y. [PMID: 34988712]
  • Yu-Hsin Tang, Po-Liang Lu, Ho-Yin Huang, Ying-Chi Lin. Clinical effectiveness of beta-lactams versus fluoroquinolones as empirical therapy in patients with diabetes mellitus hospitalized for urinary tract infections: A retrospective cohort study. PloS one. 2022; 17(3):e0266416. doi: 10.1371/journal.pone.0266416. [PMID: 35358291]
  • Tian Wei, Chengyun Zou, Jie Qin, Jianmin Tao, Li Yan, Jiangjun Wang, Hong Du, Fang Shen, Yanqin Zhao, Haiying Wang. Emergence of Hypervirulent ST11-K64 Klebsiella pneumoniae Poses a Serious Clinical Threat in Older Patients. Frontiers in public health. 2022; 10(?):765624. doi: 10.3389/fpubh.2022.765624. [PMID: 35309213]
  • D Chen, L Xiao, D Hong, Y Zhao, X Hu, S Shi, F Chen. Epidemiology of resistance of carbapenemase-producing Klebsiella pneumoniae to ceftazidime-avibactam in a Chinese hospital. Journal of applied microbiology. 2022 Jan; 132(1):237-243. doi: 10.1111/jam.15166. [PMID: 34053144]
  • Mustafa Sadek, Laurent Poirel, Manuel Dominguez Pino, Fernando D'Emidio, Stefano Pomponio, Patrice Nordmann. Evaluation of SuperCAZ/AVI® Medium for Screening Ceftazidime-avibactam Resistant Gram-negative Isolates. Diagnostic microbiology and infectious disease. 2021 Dec; 101(4):115475. doi: 10.1016/j.diagmicrobio.2021.115475. [PMID: 34419742]
  • Ammar A Hasnie, Mauricio Kahn, Robert Centor. Ur-Ine Trouble: A Case of Nephrolithiasis in A Patient with End-Stage Renal Disease. The American journal of medicine. 2021 11; 134(11):e553-e554. doi: 10.1016/j.amjmed.2021.05.017. [PMID: 34197788]
  • Murugan Thulasi Meenu, Grace Kaul, Manjulika Shukla, Kokkuvayil Vasu Radhakrishnan, Sidharth Chopra. Cudraflavone C from Artocarpus hirsutus as a Promising Inhibitor of Pathogenic, Multidrug-Resistant S. aureus, Persisters, and Biofilms: A New Insight into a Rational Explanation of Traditional Wisdom. Journal of natural products. 2021 10; 84(10):2700-2708. doi: 10.1021/acs.jnatprod.1c00578. [PMID: 34546736]
  • Kun Feng, Nan Jia, Peijuan Zhu, Serubbabel Sy, Yanfei Liu, Dandan Dong, Shixing Zhu, Jiayuan Zhang, Yuwei Liu, Frederico S Martins, Hugh Gong, Zhihua Lv, Mingming Yu, Sherwin K B Sy, Yuanqi Zhu. Aztreonam/avibactam effect on pharmacodynamic indices for mutant selection of Escherichia coli and Klebsiella pneumoniae harbouring serine- and New Delhi metallo-β-lactamases. The Journal of antimicrobial chemotherapy. 2021 10; 76(11):2875-2883. doi: 10.1093/jac/dkab292. [PMID: 34383928]
  • Johanna Berkhout, Maria J Melchers, Anita C van Mil, Claudia M Lagarde, Wright W Nichols, Johan W Mouton. Evaluation of the post-antibiotic effect in vivo for the combination of a β-lactam antibiotic and a β-lactamase inhibitor: ceftazidime-avibactam in neutropenic mouse thigh and lung infections. Journal of chemotherapy (Florence, Italy). 2021 Oct; 33(6):400-408. doi: 10.1080/1120009x.2021.1892365. [PMID: 33682636]
  • Anil R Maharaj, Huali Wu, Kanecia O Zimmerman, William J Muller, Janice E Sullivan, Catherine M T Sherwin, Julie Autmizguine, Mobeen H Rathore, Chi D Hornik, Amira Al-Uzri, Elizabeth H Payne, Daniel K Benjamin, Christoph P Hornik. Pharmacokinetics of Ceftazidime in Children and Adolescents with Obesity. Paediatric drugs. 2021 Sep; 23(5):499-513. doi: 10.1007/s40272-021-00460-4. [PMID: 34302290]
  • Véronique Goncette, Nathalie Layios, Julie Descy, Frédéric Frippiat. Continuous infusion, therapeutic drug monitoring and outpatient parenteral antimicrobial therapy with ceftazidime/avibactam: a retrospective cohort study. Journal of global antimicrobial resistance. 2021 09; 26(?):15-19. doi: 10.1016/j.jgar.2021.04.015. [PMID: 33989847]
  • Elham Isaei, Shahla Mansouri, Maryam Rahmani, Fariba Sharififar, Atefeh Salary. Novel Synergistic Activity of Quercus infectoria Gall Extract with Ceftazidime Against Standard and Multiple Drug Resistant Pseudomonas aeruginosa and Escherichia coli Isolates. Archives of Iranian medicine. 2021 09; 24(9):684-688. doi: 10.34172/aim.2021.98. [PMID: 34816684]
  • Punit J Shah, Thuytram Tran, Francis Emelogu, Farheen Tariq. Aztreonam, Ceftazidime/Avibactam, and Colistin Combination for the Management of Carbapenemase-Producing Klebsiella Pneumoniae Bacteremia: A Case Report. Journal of pharmacy practice. 2021 Aug; 34(4):653-657. doi: 10.1177/0897190019882262. [PMID: 31698984]
  • Joan Bergman, Lainey Harvill, Shawna Hawkins, Kurt Sladky, Sherry Cox. Determination of ceftazidime in plasma by RP-HPLC and ultraviolet detection. Biomedical chromatography : BMC. 2021 Jul; 35(7):e5104. doi: 10.1002/bmc.5104. [PMID: 33629742]
  • Shawna J Hawkins, Sherry K Cox, Kurt K Sladky. Pharmacokinetics of ceftazidime in Northern leopard frogs (Lithobates pipiens) at two different doses and administration routes. American journal of veterinary research. 2021 Jul; 82(7):560-565. doi: 10.2460/ajvr.82.7.560. [PMID: 34166088]
  • Christina D McNeal, Clare A Ryan, Londa J Berghaus, Brenton C Credille, Chih-Ping Lo, Virginia R Fajt. Plasma disposition of ceftazidime in healthy neonatal foals following intravenous and intramuscular administration. Journal of veterinary pharmacology and therapeutics. 2021 Jul; 44(4):560-567. doi: 10.1111/jvp.12947. [PMID: 33511670]
  • Marianna Meschiari, Iacopo Franconi, Erica Bacca, Vincenzo Bianco, Gabriella Orlando, Gianluca Cuomo, Andrea Bedini, Cristina Mussini. Ceftazidime/avibactam and ceftolozane/tazobactam for the treatment of extensively drug-resistant Pseudomonas aeruginosa post-neurosurgical infections: three cases and a review of the literature. Infection. 2021 Jun; 49(3):549-553. doi: 10.1007/s15010-020-01539-9. [PMID: 33074365]
  • ChangDong Lin, Yue Li, YueBin Zhang, ZhaoYuan Liu, Xia Mu, Chenjian Gu, Jing Liu, Yutang Li, GuoHui Li, JianFeng Chen. Ceftazidime is a potential drug to inhibit SARS-CoV-2 infection in vitro by blocking spike protein-ACE2 interaction. Signal transduction and targeted therapy. 2021 05; 6(1):198. doi: 10.1038/s41392-021-00619-y. [PMID: 34006835]
  • Zhengwu Shen, Wei Xu, Jingfeng Yu, Lixia Chen, Jinghua Zhang, Sihan Sheng, Xun Dong, Hongzhu Bian. Synthesis and in vitro antibacterial activity of new aminothiazole-oximepiperidone cephalosporins. Bioorganic & medicinal chemistry letters. 2021 05; 40(?):127928. doi: 10.1016/j.bmcl.2021.127928. [PMID: 33705899]
  • Francesco Perrotta, Marco Paolo Perrini. Successful Treatment of Klebsiella pneumoniae NDM Sepsis and Intestinal Decolonization with Ceftazidime/Avibactam Plus Aztreonam Combination in a Patient with TTP Complicated by SARSCoV-2 Nosocomial Infection. Medicina (Kaunas, Lithuania). 2021 Apr; 57(5):. doi: 10.3390/medicina57050424. [PMID: 33924769]
  • Raja Amarendra Muthina, Naveen Kumar Koppara, Maria Bethasaida Manuel, Alekhya Naga Bommu, Sunnesh Reddy Anapalli, Sangeetha Lakshmi Boju, Ram Rapur, Siva Kumar Vishnubotla. Cerebral abscess and calvarial osteomyelitis caused by Burkholderia pseudomallei in a renal transplant recipient. Transplant infectious disease : an official journal of the Transplantation Society. 2021 Apr; 23(2):e13530. doi: 10.1111/tid.13530. [PMID: 33248011]
  • Jie Zhou, Xiang You, Meng Ke, Lingling Ye, Wanhong Wu, Pinfang Huang, Cuihong Lin. Dosage Adjustment for Ceftazidime in Pediatric Patients With Renal Impairment Using Physiologically Based Pharmacokinetic Modeling. Journal of pharmaceutical sciences. 2021 04; 110(4):1853-1862. doi: 10.1016/j.xphs.2021.02.001. [PMID: 33556385]
  • Kari E Musgrave, Christopher S Hanley, Mark G Papich. POPULATION PHARMACOKINETICS OF CEFTAZIDIME AFTER A SINGLE SUBCUTANEOUS INJECTION AND NORMAL ORAL AND CLOACAL BACTERIAL FLORA SURVEY IN EASTERN HELLBENDERS (CRYPTOBRANCHUS ALLEGANIENSIS ALLEGANIENSIS). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2021 Apr; 52(1):90-96. doi: 10.1638/2020-0145. [PMID: 33827165]
  • Selina Schießer, Florian Hitzenbichler, Martin G Kees, Alexander Kratzer, Matthias Lubnow, Bernd Salzberger, Frieder Kees, Christoph Dorn. Measurement of Free Plasma Concentrations of Beta-Lactam Antibiotics: An Applicability Study in Intensive Care Unit Patients. Therapeutic drug monitoring. 2021 04; 43(2):264-270. doi: 10.1097/ftd.0000000000000827. [PMID: 33086362]
  • Ying Wang, Zhichao Du, Yongdong Chen, Yugang Liu, Zhitang Yang. Meta-analysis: combination of meropenem vs ceftazidime and amikacin for empirical treatment of cancer patients with febrile neutropenia. Medicine. 2021 Feb; 100(8):e24883. doi: 10.1097/md.0000000000024883. [PMID: 33663117]
  • Jeffrey R Strich, Emily Ricotta, Sarah Warner, Yi Ling Lai, Cumhur Y Demirkale, Samuel F Hohmann, Chanu Rhee, Michael Klompas, Tara Palmore, John H Powers, John P Dekker, Jennifer Adjemian, Roland Matsouaka, Christopher W Woods, Robert L Danner, Sameer S Kadri. Pharmacoepidemiology of Ceftazidime-Avibactam Use: A Retrospective Cohort Analysis of 210 US Hospitals. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2021 02; 72(4):611-621. doi: 10.1093/cid/ciaa061. [PMID: 32107536]
  • Zana Rubic, Silvija Soprek, Marko Jelic, Anita Novak, Ivana Goic-Barisic, Marina Radic, Arjana Tambic-Andrasevic, Marija Tonkic. Molecular Characterization of β-Lactam Resistance and Antimicrobial Susceptibility to Possible Therapeutic Options of AmpC-Producing Multidrug-Resistant Proteus mirabilis in a University Hospital of Split, Croatia. Microbial drug resistance (Larchmont, N.Y.). 2021 Feb; 27(2):162-169. doi: 10.1089/mdr.2020.0002. [PMID: 32429775]
  • Calvina E L Estaleva, Tomas F Zimba, John Osei Sekyere, Usha Govinden, Hafizah Y Chenia, Gunnar S Simonsen, Bjørg Haldorsen, Sabiha Y Essack, Arnfinn Sundsfjord. High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique. BMC infectious diseases. 2021 Jan; 21(1):16. doi: 10.1186/s12879-020-05696-y. [PMID: 33407206]
  • Worapong Nasomsong, Parnrada Nulsopapon, Dhitiwat Changpradub, Manat Pongchaidecha, Supanun Pungcharoenkijkul, Piraporn Juntanawiwat, Waristha Simsiriporn, Wichai Santimaleeworagun. The Potential Use of Ceftazidime-Avibactam Against Carbapenem Resistant Klebsiella pneumoniae Clinical Isolates Harboring Different Carbapenemase Types in a Thai University Hospital. Drug design, development and therapy. 2021; 15(?):3095-3104. doi: 10.2147/dddt.s321147. [PMID: 34295150]
  • Feng Xie, Shengwang Dai, Yu Zhao, Pei Huang, Shen Yu, Biao Ren, Qiushui Wang, Zengchun Ji, Gil Alterovitz, Qi Zhang, Jingyu Zhang, Xiangyin Chen, Lan Jiang, Fuhang Song, Hongwei Liu, Frederick M Ausubel, Xueting Liu, Huanqin Dai, Lixin Zhang. Generation of Fluorinated Amychelin Siderophores against Pseudomonas aeruginosa Infections by a Combination of Genome Mining and Mutasynthesis. Cell chemical biology. 2020 12; 27(12):1532-1543.e6. doi: 10.1016/j.chembiol.2020.10.009. [PMID: 33186541]
  • Dennis Kühn, Carlos Metz, Frederik Seiler, Holger Wehrfritz, Sophie Roth, Mohammad Alqudrah, André Becker, Hendrik Bracht, Stefan Wagenpfeil, Mathias Hoffmann, Robert Bals, Ulrich Hübner, Jürgen Geisel, Philipp M Lepper, Sören L Becker. Antibiotic therapeutic drug monitoring in intensive care patients treated with different modalities of extracorporeal membrane oxygenation (ECMO) and renal replacement therapy: a prospective, observational single-center study. Critical care (London, England). 2020 11; 24(1):664. doi: 10.1186/s13054-020-03397-1. [PMID: 33239110]
  • Zhiqiang Wang, Ke Ma, Zhongju Chen, Zhiliang Guo, Guangyuan Zhao, Hui Guo, Lan Zhu, Gang Chen. Successful Treatment of Early Post-Transplant Bloodstream and Pulmonary Infection Caused by Carbapenem-Resistant Klebsiella pneumoniae With a Combination of Ceftazidime-Avibactam and Carbapenem: A Case Report. Transplantation proceedings. 2020 Nov; 52(9):2742-2746. doi: 10.1016/j.transproceed.2020.08.006. [PMID: 32861482]
  • Rachelle E Beattie, Troy Skwor, Krassimira R Hristova. Survivor microbial populations in post-chlorinated wastewater are strongly associated with untreated hospital sewage and include ceftazidime and meropenem resistant populations. The Science of the total environment. 2020 Oct; 740(?):140186. doi: 10.1016/j.scitotenv.2020.140186. [PMID: 32569917]
  • Ting Li, Guang-Shing Cheng, Sudhakar N J Pipavath, Gregory A Kicska, Liangjin Liu, Paul E Kinahan, Wei Wu. The novel coronavirus disease (COVID-19) complicated by pulmonary embolism and acute respiratory distress syndrome. Journal of medical virology. 2020 10; 92(10):2205-2208. doi: 10.1002/jmv.26068. [PMID: 32470156]
  • Yesim Coskun, Serkan Atici. Successful Treatment of Pandrug-resistant Klebsiella pneumoniae Infection With Ceftazidime-avibactam in a Preterm Infant: A Case Report. The Pediatric infectious disease journal. 2020 09; 39(9):854-856. doi: 10.1097/inf.0000000000002807. [PMID: 32804464]
  • S Bui, A Facchin, P Ha, S Bouchet, S Leroux, F Nacka, M Fayon, E Jacqz-Aigrain. Population pharmacokinetics of ceftazidime in critically ill children: impact of cystic fibrosis. The Journal of antimicrobial chemotherapy. 2020 08; 75(8):2232-2239. doi: 10.1093/jac/dkaa170. [PMID: 32457995]
  • Upendo O Kibwana, Mtebe Majigo, Doreen Kamori, Joel Manyahi. High fecal carriage of extended Beta Lactamase producing Enterobacteriaceae among adult patients admitted in referral hospitals in Dar es Salaam, Tanzania. BMC infectious diseases. 2020 Jul; 20(1):557. doi: 10.1186/s12879-020-05272-4. [PMID: 32736605]
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