Cefoperazone (BioDeep_00000397465)
Main id: BioDeep_00000002202
natural product
代谢物信息卡片
Cefoperazone (Cefobid)
化学式: C25H27N9O8S2 (645.1423942000001)
中文名称: 头孢哌酮
谱图信息:
最多检出来源 Homo sapiens(urine) 35.85%
分子结构信息
SMILES: C1(CS[C@]2(N(C=1C(=O)O)C([C@H]2NC(=O)[C@@H](C3=CC=C(C=C3)O)NC(N4C(C(N(CC4)CC)=O)=O)=O)=O)[H])CSC5=NN=NN5C
InChI: InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16+,22+/m0/s1
描述信息
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance.
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
CONFIDENCE standard compound; INTERNAL_ID 1050
同义名列表
数据库引用编号
28 个数据库交叉引用编号
- ChEBI: CHEBI:3493
- KEGG: C06883
- KEGGdrug: D07645
- PubChem: 44187
- DrugBank: DB01329
- ChEMBL: CHEMBL507674
- MeSH: Cefoperazone
- CAS: 62893-20-3
- CAS: 62893-19-0
- MoNA: AU105011
- MoNA: AU105008
- MoNA: AU105007
- MoNA: CCMSLIB00000078201
- MoNA: CCMSLIB00000078200
- MoNA: AU105005
- MoNA: AU105004
- MoNA: AU105003
- MoNA: AU105002
- MoNA: AU105001
- MetaboLights: MTBLC3493
- ChEBI: CHEBI:184853
- PubChem: 9100
- NIKKAJI: J19.295C
- RefMet: Cefoperazone
- KEGG: C08112
- PubChem: 10312
- KNApSAcK: 3494
- KNApSAcK: 184853
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dongying Li, Yueyi Li, Jingyi Wang, Weifeng Yang, Kaiyu Cui, Renjing Su, Lu Li, Xing Ren, Xianyu Li, Yi Wang. In-depth analysis of the treatment effect and synergistic mechanism of TanReQing injection on clinical multi-drug resistant Pseudomonas aeruginosa.
Microbiology spectrum.
2024 Apr; 12(4):e0272623. doi:
10.1128/spectrum.02726-23. [PMID: 38415603] - Xupeng Shao, Yuanyuan Ren, Na Xie, Kailiang Fan, Haiyan Sun, Jiamin Lu, Jiuxiang Wei, Xincheng Tian. Effect of Cefoperazone/Sulbactam on Blood Coagulation Function in Infected Emergency Department Patients and the Necessity of Vitamin K1 (VK1) Preventive Intervention: A Single-Center, Retrospective Analysis.
Medical science monitor : international medical journal of experimental and clinical research.
2023 Jun; 29(?):e939203. doi:
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International journal of clinical practice.
2022; 2022(?):7273627. doi:
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mSphere.
2021 05; 6(3):. doi:
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Communications biology.
2021 03; 4(1):316. doi:
10.1038/s42003-021-01841-8. [PMID: 33750910] - Yee-Huang Ku, Wen-Liang Yu. Cefoperazone/sulbactam: New composites against multiresistant gram negative bacteria?.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
2021 03; 88(?):104707. doi:
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mBio.
2011; 2(3):e00066-11. doi:
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Talanta.
2010 Dec; 83(2):312-9. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Nov; 878(30):3119-24. doi:
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Antimicrobial agents and chemotherapy.
2010 Sep; 54(9):3998-9. doi:
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Journal of dairy science.
2010 Sep; 93(9):4105-10. doi:
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BMC infectious diseases.
2010 Aug; 10(?):245. doi:
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Journal of tropical pediatrics.
2010 Aug; 56(4):278-9. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2010 Jul; 30(7):772-3. doi:
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Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2010 Jul; 21(4):732-4. doi:
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Antimicrobial agents and chemotherapy.
2010 May; 54(5):2278-9. doi:
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Journal of medical case reports.
2010 Mar; 4(?):101. doi:
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Urology annals.
2010 Jan; 2(1):7-11. doi:
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Veterinary research.
2010 Jan; 41(1):1. doi:
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Fa yi xue za zhi.
2009 Dec; 25(6):437-9. doi:
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Talanta.
2009 Nov; 80(1):117-26. doi:
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European journal of medicinal chemistry.
2009 Nov; 44(11):4455-60. doi:
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Drug metabolism letters.
2009 Aug; 3(3):144-51. doi:
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Indian journal of nephrology.
2009 Jul; 19(3):107-11. doi:
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BMC microbiology.
2009 May; 9(?):94. doi:
10.1186/1471-2180-9-94. [PMID: 19445680] - Wen-Kui Wang, Li-Zhong Han, Li Yang, Yu-Xing Ni. [Analysis of the molecular epidemiology and distribution of pathogenic bacteria in burn wards of Ruijin Hospital from 2004 to 2006].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns.
2009 Apr; 25(2):94-7. doi:
NULL. [PMID: 19799031] - Kamil Cam, Ali Kayikci, Ali Erol. Prospective evaluation of the efficacy of antibiotic prophylaxis before cystoscopy.
Indian journal of urology : IJU : journal of the Urological Society of India.
2009 Apr; 25(2):203-6. doi:
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Acta poloniae pharmaceutica.
2009 Mar; 66(2):181-5. doi:
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International journal of molecular sciences.
2009 Feb; 10(2):629-645. doi:
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Journal of laboratory physicians.
2009 Jan; 1(1):7-10. doi:
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Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
2008 Nov; 91(11):1760-4. doi:
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BMC infectious diseases.
2008 Oct; 8(?):151. doi:
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Biomedical imaging and intervention journal.
2008 Oct; 4(4):e24. doi:
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Indian journal of pharmacology.
2008 Oct; 40(5):230-4. doi:
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BMC gastroenterology.
2008 Sep; 8(?):42. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1385-405. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2008 Jul; 36(7):1275-82. doi:
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Drug metabolism and disposition: the biological fate of chemicals.
2008 Jun; 36(6):1088-96. doi:
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Analytical chemistry.
2008 May; 80(10):3832-7. doi:
10.1021/ac800100y. [PMID: 18407673] - Melek Demir, Nural Cevahir, Ilknur Kaleli, Umut Yildirim, Rasim Sahin, Ebru Cevik Tepeli. [Investigation of siderophore, total matrix protease and elastase activity in Pseudomonas aeruginosa isolates from lower respiratory tract and extra-respiratory tract samples].
Mikrobiyoloji bulteni.
2008 Apr; 42(2):197-208. doi:
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Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns.
2008 Apr; 24(2):87-9. doi:
NULL. [PMID: 18785403] - Sheng Lou, Wei Li, Qin Hu. Influence of cefoperazone and azithromycin on the pharmacokinetics of pazufloxacin in rats.
European journal of drug metabolism and pharmacokinetics.
2007 Oct; 32(4):219-23. doi:
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Analytica chimica acta.
2007 Sep; 599(2):271-8. doi:
10.1016/j.aca.2007.07.071. [PMID: 17870290]