Malonylgenistin (BioDeep_00000395876)

Main id: BioDeep_00000003686

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid

化学式: C24H22O13 (518.106)
中文名称: 6“-O-丙二酸剑红素,游离酸, 6-O-丙二酰染料木苷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)OC4C(C(C(C(O4)COC(=O)CC(=O)O)O)O)O)O
InChI: InChI=1S/C24H22O13/c25-11-3-1-10(2-4-11)13-8-34-15-6-12(5-14(26)19(15)20(13)30)36-24-23(33)22(32)21(31)16(37-24)9-35-18(29)7-17(27)28/h1-6,8,16,21-26,31-33H,7,9H2,(H,27,28)/t16-,21+,22-,23+,24+/m0/s1

描述信息

Malonylgenistin is a glycosyloxyisoflavone that is genistin in which the hydroxy hydrogen at position 6 has been replaced by a malonyl group. It has a role as a plant metabolite. It is a glycosyloxyisoflavone, a hydroxyisoflavone, a malonate ester, a monosaccharide derivative and a beta-D-glucoside. It is functionally related to a genistein 7-O-beta-D-glucoside.
6-O-Malonylgenistin is a natural product found in Maackia amurensis, Glycine, and other organisms with data available.
A glycosyloxyisoflavone that is genistin in which the hydroxy hydrogen at position 6 has been replaced by a malonyl group.

同义名列表

26 个代谢物同义名

3-oxo-3-[[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-3-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methoxy]propanoic acid; PROPANEDIOIC ACID, 6-ESTER WITH 7-(.BETA.-D-GLUCOPYRANOSYLOXY)-5-HYDROXY-3-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; Propanedioic acid, 6-ester with 7-(beta-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5-hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl 6-O-(carboxyacetyl)-beta-D-glucopyranoside; 5-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(carboxylatoacetyl)hexopyranoside; Malonyl genistin (constituent of soy isoflavones) [DSC]; GENISTEIN-7-O-.BETA.-D-GLUCOSYL-6-O-MALONATE; Genistein 7-O-beta-d-glucoside-6-O-malonate; genistein 7-O-beta-D-glucoside 6-O-malonate; Genistein-7-o-beta-D-glucosyl-6-o-malonate; Genistein 7-O-glucoside-6-malonate; 7-O-Glucosyl-6-malonyl Genistein; 6"-O-Malonylgenistin, Free Acid; FRAUJUKWSKMNJY-RSEYPYQYSA-N; Genistin 6-O-Malonate; 6-O-Malonylgenistin"; 6-O-Malonylgenistin; 6-Malonylgenistin; Genistin Malonate; Malonyl-genistin; malonyl genistin; Malonylgenistin; UNII-2AUB85VT2K; MEGxp0_000226; ACon0_001356; 2AUB85VT2K



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

37 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ACE, ELANE, GZMB, PPARG, TYR
Peripheral membrane protein 1 GBA1
Endoplasmic reticulum membrane 2 HSP90B1, SFTPD
Nucleus 4 GZMB, HSP90B1, PPARA, PPARG
cytosol 5 ACACA, ELANE, GZMB, HSP90B1, PPARG
phagocytic vesicle 1 ELANE
trans-Golgi network 1 GBA1
nucleoplasm 2 PPARA, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 1 ACE
cell surface 1 ELANE
Golgi apparatus 1 GBA1
lysosomal membrane 2 GAA, GBA1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 ACACA
Lysosome 5 ACE, GAA, GBA1, SFTPD, TYR
endosome 1 ACE
plasma membrane 2 ACE, GAA
Membrane 4 ACE, GAA, GZMB, HSP90B1
extracellular exosome 5 ACE, ELANE, GAA, GBA1, HSP90B1
Lysosome membrane 2 GAA, GBA1
Lumenal side 1 GBA1
endoplasmic reticulum 2 GBA1, HSP90B1
extracellular space 3 ACE, ELANE, SFTPD
lysosomal lumen 2 GAA, GBA1
perinuclear region of cytoplasm 3 HSP90B1, PPARG, TYR
mitochondrion 1 ACACA
protein-containing complex 1 HSP90B1
intracellular membrane-bounded organelle 4 GAA, GZMB, PPARG, TYR
Single-pass type I membrane protein 2 ACE, TYR
Secreted 3 ACE, GAA, GZMB
extracellular region 6 ACE, ELANE, GAA, GZMB, HSP90B1, SFTPD
external side of plasma membrane 1 ACE
multivesicular body 1 SFTPD
actin cytoskeleton 1 ACACA
Melanosome membrane 1 TYR
midbody 1 HSP90B1
Golgi-associated vesicle 1 TYR
focal adhesion 1 HSP90B1
collagen trimer 1 SFTPD
collagen-containing extracellular matrix 2 ELANE, HSP90B1
secretory granule 1 ELANE
receptor complex 1 PPARG
chromatin 2 PPARA, PPARG
brush border membrane 1 ACE
sperm midpiece 1 ACE
fibrillar center 1 ACACA
tertiary granule membrane 1 GAA
Melanosome 2 HSP90B1, TYR
sperm plasma membrane 1 HSP90B1
basal plasma membrane 1 ACE
endoplasmic reticulum lumen 1 HSP90B1
transcription repressor complex 1 ELANE
specific granule lumen 1 ELANE
endocytic vesicle 1 SFTPD
azurophil granule membrane 1 GAA
azurophil granule lumen 1 ELANE
immunological synapse 1 GZMB
clathrin-coated endocytic vesicle 1 SFTPD
Sarcoplasmic reticulum lumen 1 HSP90B1
ficolin-1-rich granule membrane 1 GAA
Cytoplasmic vesicle, phagosome 1 ELANE
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
Cytolytic granule 1 GZMB
cytolytic granule lumen 1 GZMB
autolysosome lumen 1 GAA
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE


文献列表

  • Miwako Toyofuku, Fuki Okutani, Masaru Nakayasu, Shoichiro Hamamoto, Hisabumi Takase, Kazufumi Yazaki, Akifumi Sugiyama. Enhancement of developmentally regulated daidzein secretion from soybean roots in field conditions as compared with hydroponic culture. Bioscience, biotechnology, and biochemistry. 2021 Apr; 85(5):1165-1169. doi: 10.1093/bbb/zbab017. [PMID: 33784734]
  • You Jin Lim, Ho Young Jeong, Chan Saem Gil, Soon-Jae Kwon, Jong Kuk Na, Chanhui Lee, Seok Hyun Eom. Isoflavone accumulation and the metabolic gene expression in response to persistent UV-B irradiation in soybean sprouts. Food chemistry. 2020 Jan; 303(?):125376. doi: 10.1016/j.foodchem.2019.125376. [PMID: 31442900]
  • You Jin Lim, Bora Lim, Hae Yeong Kim, Soon-Jae Kwon, Seok Hyun Eom. Deglycosylation patterns of isoflavones in soybean extracts inoculated with two enzymatically different strains of lactobacillus species. Enzyme and microbial technology. 2020 Jan; 132(?):109394. doi: 10.1016/j.enzmictec.2019.109394. [PMID: 31731960]
  • Agnieszka Hanaka, Sławomir Dresler, Magdalena Wójciak-Kosior, Maciej Strzemski, Jozef Kováčik, Michał Latalski, Grażyna Zawiślak, Ireneusz Sowa. The Impact of Long-and Short-Term Strontium Treatment on Metabolites and Minerals in Glycine max. Molecules (Basel, Switzerland). 2019 Oct; 24(21):. doi: 10.3390/molecules24213825. [PMID: 31652846]
  • José P da Graça, Tatiana E Ueda, Tatiani Janegitz, Simone S Vieira, Mariana C Salvador, Maria C N de Oliveira, Sonia M Zingaretti, Stephen J Powers, John A Pickett, Michael A Birkett, Clara B Hoffmann-Campo. The natural plant stress elicitor cis-jasmone causes cultivar-dependent reduction in growth of the stink bug, Euschistus heros and associated changes in flavonoid concentrations in soybean, Glycine max. Phytochemistry. 2016 Nov; 131(?):84-91. doi: 10.1016/j.phytochem.2016.08.013. [PMID: 27659594]
  • Heung Joo Yuk, Yeong Hun Song, Marcus J Curtis-Long, Dae Wook Kim, Su Gyeong Woo, Yong Bok Lee, Zia Uddin, Cha Young Kim, Ki Hun Park. Ethylene Induced a High Accumulation of Dietary Isoflavones and Expression of Isoflavonoid Biosynthetic Genes in Soybean (Glycine max) Leaves. Journal of agricultural and food chemistry. 2016 Oct; 64(39):7315-7324. doi: 10.1021/acs.jafc.6b02543. [PMID: 27626287]
  • Yan Zhang, Sam K C Chang. Isoflavone Profiles and Kinetic Changes during Ultra-High Temperature Processing of Soymilk. Journal of food science. 2016 Mar; 81(3):C593-9. doi: 10.1111/1750-3841.13236. [PMID: 26814612]
  • Yeming Chen, Sam K C Chang. Macronutrients, Phytochemicals, and Antioxidant Activity of Soybean Sprout Germinated with or without Light Exposure. Journal of food science. 2015 Jun; 80(6):S1391-8. doi: 10.1111/1750-3841.12868. [PMID: 25916398]
  • Bingrui Liu, Kenneth T Kongstad, Sun Qinglei, Nils T Nyberg, Anna K Jäger, Dan Staerk. Dual high-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of minor and major constituents directly from the crude extract of Pueraria lobata. Journal of natural products. 2015 Feb; 78(2):294-300. doi: 10.1021/np5009416. [PMID: 25679337]
  • Vamsidhar Yerramsetty, Daniel D Gallaher, Baraem Ismail. Malonylglucoside conjugates of isoflavones are much less bioavailable compared with unconjugated β-glucosidic forms in rats. The Journal of nutrition. 2014 May; 144(5):631-7. doi: 10.3945/jn.114.190801. [PMID: 24647389]