Vernodalol (BioDeep_00000003808)

 

Secondary id: BioDeep_00000406826

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Vernodalol

化学式: C20H24O8 (392.1471)
中文名称:
谱图信息: 最多检出来源 Viridiplantae(plant) 65.95%

分子结构信息

SMILES: C=CC12COC(=O)C(=C)C1C(O)C(C(=C)C(=O)OC)C(OC(=O)C(=C)CO)C2
InChI: InChI=1S/C20H24O8/c1-6-20-7-13(28-17(23)10(2)8-21)14(11(3)18(24)26-5)16(22)15(20)12(4)19(25)27-9-20/h6,13-16,21-22H,1-4,7-9H2,5H3/t13-,14+,15+,16-,20+/m0/s1

描述信息

同义名列表

2 个代谢物同义名

Vernodalol; Vernodalol



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

35 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AKT1, CASP9, MCL1, MTOR, PIK3R6, PML, STAT3
Peripheral membrane protein 3 MTOR, PIK3R6, PML
Endoplasmic reticulum membrane 2 MTOR, PML
Nucleus 7 AKT1, CASP9, GABPA, MCL1, MTOR, PML, STAT3
cytosol 8 AKT1, CASP9, DIABLO, MCL1, MTOR, PIK3R6, PML, STAT3
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
nucleoplasm 6 AKT1, GABPA, MCL1, MTOR, PML, STAT3
RNA polymerase II transcription regulator complex 1 STAT3
Cell membrane 3 AKT1, PIK3R6, TNF
Cytoplasmic side 2 MTOR, PML
lamellipodium 1 AKT1
Early endosome membrane 1 PML
Golgi apparatus membrane 1 MTOR
cell cortex 1 AKT1
cell surface 2 TNF, TNFRSF10B
glutamatergic synapse 1 AKT1
Golgi membrane 1 MTOR
lysosomal membrane 2 GAA, MTOR
neuronal cell body 1 TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 DIABLO
Lysosome 2 GAA, MTOR
plasma membrane 6 AKT1, GAA, PIK3R6, STAT3, TNF, TNFRSF10B
Membrane 7 AKT1, DIABLO, GAA, MCL1, MTOR, PIK3R6, TNFRSF10B
extracellular exosome 1 GAA
Lysosome membrane 2 GAA, MTOR
extracellular space 1 TNF
lysosomal lumen 1 GAA
mitochondrion 3 CASP9, DIABLO, MCL1
protein-containing complex 2 AKT1, CASP9
intracellular membrane-bounded organelle 1 GAA
Microsome membrane 1 MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Secreted 1 GAA
extracellular region 2 GAA, TNF
cytoplasmic side of plasma membrane 1 DIABLO
Mitochondrion outer membrane 1 MTOR
Single-pass membrane protein 1 MCL1
mitochondrial outer membrane 2 MCL1, MTOR
transcription regulator complex 1 STAT3
Bcl-2 family protein complex 1 MCL1
nuclear membrane 1 PML
CD40 receptor complex 1 DIABLO
external side of plasma membrane 1 TNF
microtubule cytoskeleton 1 AKT1
nucleolus 1 PML
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 1 TNF
spindle 1 AKT1
Nucleus, PML body 2 MTOR, PML
PML body 2 MTOR, PML
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 2 AKT1, DIABLO
ciliary basal body 1 AKT1
chromatin 2 GABPA, STAT3
phagocytic cup 1 TNF
chromosome, telomeric region 1 PML
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
myosin complex 1 MCL1
Nucleus, nucleoplasm 1 MCL1
tertiary granule membrane 1 GAA
nuclear matrix 1 PML
phosphatidylinositol 3-kinase complex 1 PIK3R6
phosphatidylinositol 3-kinase complex, class IA 1 PIK3R6
azurophil granule membrane 1 GAA
apoptosome 1 CASP9
ficolin-1-rich granule membrane 1 GAA
Cytoplasmic vesicle, phagosome 1 MTOR
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
autolysosome lumen 1 GAA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3R6
caspase complex 1 CASP9
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Njogu M Kimani, Josphat C Matasyoh, Marcel Kaiser, Reto Brun, Thomas J Schmidt. Sesquiterpene Lactones from Vernonia cinerascens Sch. Bip. and Their in Vitro Antitrypanosomal Activity. Molecules (Basel, Switzerland). 2018 Jan; 23(2):. doi: 10.3390/molecules23020248. [PMID: 29382040]
  • Carmina Sirignano, Alì Snene, Daniela Rigano, Sofia Tapanelli, Carmen Formisano, Paolo Luciano, Ridha El Mokni, Saoussen Hammami, Alain Rodrigue Tenoh, Annette Habluetzel, Orazio Taglialatela-Scafati. Angeloylated Germacranolides from Daucus virgatus and Their Plasmodium Transmission Blocking Activity. Journal of natural products. 2017 10; 80(10):2787-2794. doi: 10.1021/acs.jnatprod.7b00603. [PMID: 28976194]
  • Annamaria Sinisi, Estrella Millán, Solomon M Abay, Annette Habluetzel, Giovanni Appendino, Eduardo Muñoz, Orazio Taglialatela-Scafati. Poly-Electrophilic Sesquiterpene Lactones from Vernonia amygdalina: New Members and Differences in Their Mechanism of Thiol Trapping and in Bioactivity. Journal of natural products. 2015 Jul; 78(7):1618-23. doi: 10.1021/acs.jnatprod.5b00179. [PMID: 26115003]
  • Kirandeep Kaur, Meenakshi Jain, Tarandeep Kaur, Rahul Jain. Antimalarials from nature. Bioorganic & medicinal chemistry. 2009 May; 17(9):3229-56. doi: 10.1016/j.bmc.2009.02.050. [PMID: 19299148]