6-Aminopenicillanic acid (BioDeep_00000003732)

 

Secondary id: BioDeep_00000406314

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite natural product


代谢物信息卡片


(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

化学式: C8H12N2O3S (216.0569)
中文名称: 6-氨基青霉烷酸
谱图信息: 最多检出来源 Homo sapiens(plant) 13.5%

分子结构信息

SMILES: CC1(C(N2C(S1)C(C2=O)N)C(=O)O)C
InChI: InChI=1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1

描述信息

D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D010406 - Penicillins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
6-Aminopenicillanic acid is a metabolite of penicillin v; penicillin g.

同义名列表

26 个代谢物同义名

(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; 6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Aminopenicillanic acid, potassium salt; Aminopenicillanic acid, sodium salt; Phenacyl 6-aminopenicillinic acid; Phenacyl 6-aminopenicillinate; 6beta-Aminopenicillanic acid; (+)-6-Aminopenicillanic acid; 6b-Aminopenicillanic acid; 6Β-aminopenicillanic acid; 6-Aminopenicillamine acid; (+)-6-Aminopenicillanate; 6-Aminopenicillanic acid; 6beta-Aminopenicillanate; Aminopenicillanic acid; 6Β-aminopenicillanate; 6b-Aminopenicillanate; 6-Aminopenicillanate; Aminopenicillanate; 6-APA CPD; Penicin; Penin; 6-APA; 6-Aps; 6-Aminopenicillanate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 AXIN2, CAMP, DAO, DNM1, FPR1, HMGB1, LPO, PTGS2, TBP
Peripheral membrane protein 3 DAO, HMGB1, PTGS2
Endoplasmic reticulum membrane 1 PTGS2
Nucleus 5 AXIN2, CAMP, HMGB1, OMP, TBP
cytosol 3 AXIN2, DAO, OMP
nuclear body 1 CAMP
trans-Golgi network 1 POSTN
centrosome 1 AXIN2
nucleoplasm 4 ATP2B1, CAMP, HMGB1, TBP
Cell membrane 7 ATP2B1, DAO, DNM1, FPR1, HMGB1, SLC4A4, SLC7A1
Multi-pass membrane protein 4 ATP2B1, FPR1, SLC4A4, SLC7A1
Synapse 3 ATP2B1, DNM1, OMP
cell surface 2 HMGB1, SLC4A4
glutamatergic synapse 2 ATP2B1, DNM1
Golgi apparatus 1 POSTN
neuromuscular junction 1 POSTN
neuronal cell body 1 OMP
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 DAO
Presynapse 1 DNM1
endosome 1 HMGB1
plasma membrane 10 ATP2B1, AXIN2, DAO, DNM1, FPR1, HMGB1, IGHE, KNG1, SLC4A4, SLC7A1
presynaptic active zone 1 DAO
synaptic vesicle membrane 1 ATP2B1
Membrane 4 ATP2B1, FPR1, SLC4A4, SLC7A1
apical plasma membrane 1 SLC7A1
axon 1 OMP
basolateral plasma membrane 4 ATP2B1, LPO, SLC4A4, SLC7A1
caveola 1 PTGS2
extracellular exosome 9 ATP2B1, CAMP, CPVL, DAO, DNM1, KNG1, LPO, LYZ, SLC4A4
endoplasmic reticulum 2 HMGB1, PTGS2
extracellular space 8 CAMP, DAO, HMGB1, IGHE, KNG1, LPO, LYZ, POSTN
bicellular tight junction 1 DAO
protein-containing complex 3 PTGS2, SLC7A1, TBP
intracellular membrane-bounded organelle 1 ATP2B1
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 1 IGHE
Secreted 5 CAMP, DAO, HMGB1, LPO, POSTN
extracellular region 7 CAMP, DAO, HMGB1, IGHE, KNG1, LPO, LYZ
Extracellular side 2 DAO, HMGB1
photoreceptor inner segment 1 DNM1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Secreted, extracellular space, extracellular matrix 1 POSTN
beta-catenin destruction complex 1 AXIN2
cytoplasmic vesicle 1 DNM1
Membrane, clathrin-coated pit 1 DNM1
clathrin-coated pit 1 DNM1
vesicle 1 CAMP
Cytoplasm, cytoskeleton, spindle 1 CAMP
microtubule 1 DNM1
spindle 1 CAMP
extracellular matrix 1 POSTN
Peroxisome 1 DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 2 KNG1, POSTN
lateral plasma membrane 2 ATP2B1, SLC4A4
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
chromatin 1 TBP
IgE immunoglobulin complex 1 IGHE
cell projection 4 ATP2B1, CAMP, DAO, DNM1
Chromosome 2 CAMP, HMGB1
Secreted, extracellular space 2 DAO, KNG1
blood microparticle 1 KNG1
Basolateral cell membrane 2 ATP2B1, SLC4A4
[Isoform 2]: Cell membrane 1 IGHE
Chromosome, centromere, kinetochore 1 CAMP
female germ cell nucleus 1 TBP
euchromatin 1 TBP
Presynaptic cell membrane 1 ATP2B1
basal plasma membrane 1 SLC7A1
specific granule 1 CAMP
ficolin-1-rich granule lumen 1 HMGB1
secretory granule lumen 1 HMGB1
secretory granule membrane 1 FPR1
endoplasmic reticulum lumen 2 KNG1, PTGS2
transcription repressor complex 1 HMGB1
male germ cell nucleus 1 TBP
transcription factor TFIID complex 1 TBP
platelet alpha granule lumen 1 KNG1
specific granule lumen 3 CAMP, DAO, LYZ
tertiary granule lumen 2 CAMP, LYZ
kinetochore 1 CAMP
endocytic vesicle 1 DNM1
azurophil granule membrane 1 FPR1
azurophil granule lumen 1 LYZ
immunological synapse 1 ATP2B1
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
ficolin-1-rich granule membrane 1 FPR1
female pronucleus 1 TBP
male pronucleus 1 TBP
membrane coat 1 DNM1
condensed chromosome 2 CAMP, HMGB1
[Isoform 3]: Cell membrane 1 IGHE
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
Cytoplasmic vesicle, secretory vesicle, chromaffin granule 1 DNM1
chromaffin granule 1 DNM1
presynaptic endocytic zone membrane 1 DNM1
photoreceptor ribbon synapse 2 ATP2B1, DNM1
RNA polymerase transcription factor SL1 complex 1 TBP
transcription factor TFIIA complex 1 TBP


文献列表

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