Vestitol (BioDeep_00000003664)

Main id: BioDeep_00000397229

 

human metabolite PANOMIX_OTCML-2023 natural product


代谢物信息卡片


(3S)-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol

化学式: C16H16O4 (272.1049)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: c1(ccc2c(c1)OC[C@@H](C2)c1c(cc(cc1)OC)O)O
InChI: InChI=1S/C16H16O4/c1-19-13-4-5-14(15(18)8-13)11-6-10-2-3-12(17)7-16(10)20-9-11/h2-5,7-8,11,17-18H,6,9H2,1H3

描述信息

同义名列表

6 个代谢物同义名

(3S)-3,4-Dihydro-3-(2-hydroxy-4-methoxyphenyl)-2H-1-benzopyran-7-ol; (3S)-Vestitol; (+)-Vestitol; Vestitol; Vestitol; Vestitol



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

11 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(1)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(10)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

39 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 APOE, BIRC3, CALM1, DAB2, FDPS, FGF10, PIK3CA, VEGFA
Nucleus 5 APOE, BIRC3, CALM1, FGF10, VEGFA
cytosol 7 BIRC3, CALM1, DAB2, FDPS, IL1B, PIK3CA, SOCS3
dendrite 1 APOE
centrosome 1 CALM1
nucleoplasm 3 BIRC3, CALM1, FDPS
Cell membrane 1 TNF
lamellipodium 1 PIK3CA
cell surface 4 FGF10, TNF, VEGFA, WNT5A
glutamatergic synapse 2 APOE, WNT5A
Golgi apparatus 2 APOE, VEGFA
Golgi membrane 1 INS
lysosomal membrane 1 DAB2
neuronal cell body 2 APOE, TNF
postsynapse 1 WNT5A
Cytoplasm, cytosol 1 IL1B
Lysosome 1 IL1B
plasma membrane 8 APOE, CALM1, CSF2, DAB2, FGF10, PIK3CA, TNF, WNT5A
Membrane 4 APOE, FDPS, VEGFA, WNT5A
extracellular exosome 3 APOE, MMP7, WNT5A
endoplasmic reticulum 2 APOE, VEGFA
extracellular space 14 APOE, CSF2, CSF3, CXCL1, CXCL2, FGF10, IL1B, IL4, IL6, INS, MMP7, TNF, VEGFA, WNT5A
lysosomal lumen 1 CSF3
perinuclear region of cytoplasm 2 DAB2, PIK3CA
Schaffer collateral - CA1 synapse 1 WNT5A
adherens junction 1 VEGFA
intercalated disc 1 PIK3CA
protein-containing complex 2 BIRC3, CALM1
intracellular membrane-bounded organelle 2 CSF2, DAB2
Secreted 10 APOE, CSF2, CSF3, FGF10, IL1B, IL4, IL6, INS, VEGFA, WNT5A
extracellular region 15 APOE, CALM1, CSF2, CSF3, CXCL1, CXCL2, FGF10, IL1B, IL4, IL6, INS, MMP7, TNF, VEGFA, WNT5A
cytoplasmic side of plasma membrane 1 SOCS3
mitochondrial matrix 1 FDPS
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 CALM1
external side of plasma membrane 1 TNF
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 4 APOE, MMP7, VEGFA, WNT5A
chylomicron 1 APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 1 APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 1 APOE
clathrin-coated vesicle membrane 1 DAB2
Early endosome 1 APOE
clathrin-coated pit 1 DAB2
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 CALM1
Membrane raft 1 TNF
Cytoplasm, cytoskeleton, spindle 1 CALM1
focal adhesion 1 DAB2
extracellular matrix 4 APOE, MMP7, VEGFA, WNT5A
Peroxisome 1 FDPS
collagen-containing extracellular matrix 1 APOE
secretory granule 2 IL1B, VEGFA
sarcomere 1 CALM1
phagocytic cup 1 TNF
Secreted, extracellular space 1 APOE
spindle pole 1 CALM1
blood microparticle 1 APOE
Cell projection, cilium, flagellum 1 CALM1
sperm midpiece 1 CALM1
Cytoplasm, cytoskeleton, spindle pole 1 CALM1
fibrillar center 1 DAB2
endosome lumen 1 INS
Melanosome 1 APOE
myelin sheath 1 CALM1
clathrin-coated vesicle 1 DAB2
voltage-gated potassium channel complex 1 CALM1
secretory granule lumen 1 INS
Golgi lumen 2 INS, WNT5A
endoplasmic reticulum lumen 4 APOE, IL6, INS, WNT5A
platelet alpha granule lumen 1 VEGFA
phosphatidylinositol 3-kinase complex 2 PIK3CA, SOCS3
phosphatidylinositol 3-kinase complex, class IA 1 PIK3CA
specific granule lumen 1 CXCL1
tertiary granule lumen 1 CXCL1
endocytic vesicle membrane 1 WNT5A
transport vesicle 1 INS
Secreted, extracellular exosome 1 IL1B
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
calyx of Held 1 CALM1
clathrin-coated endocytic vesicle membrane 2 APOE, WNT5A
calcium channel complex 1 CALM1
synaptic cleft 1 APOE
spindle microtubule 1 CALM1
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
presynaptic cytosol 1 CALM1
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 2 APOE, CSF3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
chylomicron remnant 1 APOE
intermediate-density lipoprotein particle 1 APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
catalytic complex 1 CALM1
interleukin-6 receptor complex 1 IL6
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA
phosphatidylinositol 3-kinase complex, class IB 1 PIK3CA
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Lucas Resende Dutra Sousa, Tatiane Roquete Amparo, Gustavo Henrique Bianco de Souza, Aline Tonhela Ferraz, Kátia da Silva Fonseca, Amanda Scofield de Azevedo, Andréa Mendes do Nascimento, Ângela Leão Andrade, Janaína Brandão Seibert, Thalita Marcolan Valverde, Saulo Fehelberg Pinto Braga, Paula Melo de Abreu Vieira, Viviane Martins Rebello Dos Santos. Anti-Trypanosoma cruzi Potential of Vestitol Isolated from Lyophilized Red Propolis. Molecules (Basel, Switzerland). 2023 Nov; 28(23):. doi: 10.3390/molecules28237812. [PMID: 38067542]
  • Gari Vidal Ccana-Ccapatinta, Jennyfer Andrea Aldana Mejía, Matheus Hikaru Tanimoto, Milton Groppo, Jean Carlos Andrade Sarmento de Carvalho, Jairo Kenupp Bastos. Dalbergia ecastaphyllum (L.) Taub. and Symphonia globulifera L.f.: The Botanical Sources of Isoflavonoids and Benzophenones in Brazilian Red Propolis. Molecules (Basel, Switzerland). 2020 Apr; 25(9):. doi: 10.3390/molecules25092060. [PMID: 32354180]
  • Bruno Bueno-Silva, Alexandre Marsola, Masaharu Ikegaki, Severino M Alencar, Pedro L Rosalen. The effect of seasons on Brazilian red propolis and its botanical source: chemical composition and antibacterial activity. Natural product research. 2017 Jun; 31(11):1318-1324. doi: 10.1080/14786419.2016.1239088. [PMID: 27701899]
  • Bang-yan Sun, Wen-ji He, Zhen Zhang. [Chemical Constituents from Pueraria alopecuroides Ratten]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Jul; 38(7):1433-5. doi: ". [PMID: 26946841]
  • Jin-Song Liu, Ai-Min Chen, Ying-Sheng Xu, Gang Wang, Guo-Kai Wang. [Phenolic derivatives from Wisteria sinensis sweet caulis]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2013 Sep; 36(9):1437-40. doi: . [PMID: 24620688]
  • Akira Masunaka, Mitsuro Hyakumachi, Shigehito Takenaka. Plant growth-promoting fungus, Trichoderma koningi suppresses isoflavonoid phytoalexin vestitol production for colonization on/in the roots of Lotus japonicus. Microbes and environments. 2011; 26(2):128-34. doi: 10.1264/jsme2.me10176. [PMID: 21502738]
  • Hiroaki Ueda, Yukihiro Sugimoto. Vestitol as a chemical barrier against intrusion of parasitic plant Striga hermonthica into Lotus japonicus roots. Bioscience, biotechnology, and biochemistry. 2010; 74(8):1662-7. doi: 10.1271/bbb.100285. [PMID: 20699571]
  • Suresh Awale, Feng Li, Hiroko Onozuka, Hiroyasu Esumi, Yasuhiro Tezuka, Shigetoshi Kadota. Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition. Bioorganic & medicinal chemistry. 2008 Jan; 16(1):181-9. doi: 10.1016/j.bmc.2007.10.004. [PMID: 17950610]
  • Norimoto Shimada, Shusei Sato, Tomoyoshi Akashi, Yasukazu Nakamura, Satoshi Tabata, Shin-Ichi Ayabe, Toshio Aoki. Genome-wide analyses of the structural gene families involved in the legume-specific 5-deoxyisoflavonoid biosynthesis of Lotus japonicus. DNA research : an international journal for rapid publication of reports on genes and genomes. 2007 Feb; 14(1):25-36. doi: 10.1093/dnares/dsm004. [PMID: 17452423]