IDP (BioDeep_00000003568)

 

Secondary id: BioDeep_00000413255

natural product human metabolite Endogenous BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


[({[(2R,3S,4R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid

化学式: C10H14N4O11P2 (428.0134314)
中文名称: 肌苷-5'-二磷酸
谱图信息: 最多检出来源 Macaca mulatta(otcml) 0.35%

分子结构信息

SMILES: C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2[nH]cnc3=O)O1)O)O)OP(=O)(O)OP(=O)(O)O
InChI: InChI=1S/C10H14N4O11P2/c15-6-4(1-23-27(21,22)25-26(18,19)20)24-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

描述信息

An inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. [HMDB]
IDP is an inosine nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Acquisition and generation of the data is financially supported in part by CREST/JST.

同义名列表

19 个代谢物同义名

[({[(2R,3S,4R)-3,4-dihydroxy-5-(6-oxo-6,9-dihydro-3H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid; {[(2R,3S,4R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methoxy(hydroxy)phosphoryl}oxyphosphonic acid; Inosine 5-(trihydrogen pyrophosphate); Inosine 5-(trihydrogen diphosphate); Inosine-5-diphosphate sodium salt; Inosine diphosphate (IDP); Inosine 5-pyrophosphate; Pyrophosphate, inosine; Inosine pyrophosphate; Inosine 5-diphosphate; Inosine-5-diphosphate; Diphosphate, inosine; Inosine diphosphate; Riboxine; Riboxin; 5-IDP; idp; Inosine 5'-diphosphate(IDP); IDP



数据库引用编号

29 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

49 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(1)

Plant Reactome(0)

INOH(2)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(46)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Karla Martinez Pomier, Rashik Ahmed, Giuseppe Melacini. Interactions of intrinsically disordered proteins with the unconventional chaperone human serum albumin: From mechanisms of amyloid inhibition to therapeutic opportunities. Biophysical chemistry. 2022 03; 282(?):106743. doi: 10.1016/j.bpc.2021.106743. [PMID: 35093643]
  • Catherine Lee, Matthew Schojan, Ko Myo, Gyaw Htet Doe, Lanau Htu San, Judith Bass. Implementation of a Community-Based Psychosocial Support Focal Point Response for Internally Displaced Persons in Myanmar During COVID-19. Frontiers in public health. 2022; 10(?):854490. doi: 10.3389/fpubh.2022.854490. [PMID: 35400035]
  • Shigeru Ueda, Shin-Ichi Sakasegawa. A novel assay for serum creatinine using a creatine kinase cycling reaction. Bioscience, biotechnology, and biochemistry. 2021 Apr; 85(5):1063-1068. doi: 10.1093/bbb/zbab027. [PMID: 33629709]
  • E V Ekusheva, V B Voitenkov, O A Rizakhanova. [The effectiveness of cytoflavin in complex therapy of patients with the coronavirus infection COVID-19]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2021; 121(12):33-39. doi: 10.17116/jnevro202112112133. [PMID: 35041310]
  • M V Putilina, N V Teplova, K I Bairova, A E Petrikeeva, N I Shabalina. [The result of prospective randomized study CITADEL - the efficacy and safety of drug cytoflavin in postcovid rehabilitation]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2021; 121(10):45-51. doi: 10.17116/jnevro202112110145. [PMID: 34874654]
  • Myongjae Lee, Dohee Kim, Jeongcheol Shin, Hee-Yeol Lee, Soobong Park, Hong-Sub Lee, Jae-Hoon Kang, Suk-Jae Chung. Quantification of IDP-73152, a novel antibiotic, in plasma from mice, rats and humans using an ultra-high performance liquid chromatography/tandem mass spectrometry method for use in pharmacokinetic studies. Journal of pharmaceutical and biomedical analysis. 2017 Oct; 145(?):364-371. doi: 10.1016/j.jpba.2017.06.066. [PMID: 28715789]
  • A V Deriugina, A V Shumilova. [An influence of cytoflavin on oxidative stress and activity of Na/K-ATPase of erythrocytes after brain trauma]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2017 ; 117(11):51-55. doi: 10.17116/jnevro201711711151-55. [PMID: 29265087]
  • V V Boyarintsev, I A Denisenko. Comparative evaluation of contemporary methods of treatment and rehabilitation of post-apoplexy patients. Meditsina truda i promyshlennaia ekologiia. 2016 ; ?(11):1-7. doi: NULL. [PMID: 30351684]
  • V A Dorovskikh, O N Li, N V Simonova, M A Shtarberg. [EFFECT OF CITOFLAVIN ON THE PARAMETERS OF LIPID PEROXIDATION IN BLOOD PLASMA OF RATS UNDER COLD STRESS CONDITIONS.]. Eksperimental'naia i klinicheskaia farmakologiia. 2016; 79(7):29-34. doi: . [PMID: 29782743]
  • V D Skripkо, A J Pasko, A L Kovalenko, V A Zaplutanov. [Cytoflavin rationale for the use in treatment of patients with postsurgical hypothyroidism]. Khirurgiia. 2016 ; ?(7):53-57. doi: 10.17116/hirurgia2016753-57. [PMID: 27459489]
  • I V Gatckikh, M M Petrova, T P Shalda, E L Varygina, M N Kuznetsov, A N Narkevich. Dynamics of cognitive disorders in patients with type 2 diabetes mellitus under effect of metabolic therapy. Klinicheskaia meditsina. 2016 ; 94(7):533-9. doi: NULL. [PMID: 30289219]
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  • N I Zhernakova, T V Gorbach, O V Romashchenko, V V Rumbesht. Age-related features of Cytoflavin effectiveness during experimental myocardial ischemia. Bulletin of experimental biology and medicine. 2014 Apr; 156(6):785-8. doi: 10.1007/s10517-014-2450-z. [PMID: 24824697]
  • E A Lebedeva, M E Belousova, A A Kurtasov, Z A Nemkova, M Iu Kaminskiĭ, R V Popov, S L Trofimovich. [Efficiency of intensive care with cytoflavin in patients of advanced age in combined traumatic brain injury]. Advances in gerontology = Uspekhi gerontologii. 2014; 27(3):578-83. doi: ". [PMID: 25827011]
  • E A Kartashova, M G Romantsov, I V Sarvilina. [The study of the effectiveness of drug prevention mechanisms of cardiovascular aging by cytoflavin]. Advances in gerontology = Uspekhi gerontologii. 2014; 27(4):737-45. doi: ". [PMID: 25946853]
  • O A Vodop'ianova, I Ia Moiseeva, O P Rodina, I N Kustikova, N V Antropova. [The assessment of the effects of cytoflavin and cardioxipin on the emotional status of rats with dyslipidemia]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2014; 114(7):53-5. doi: ". [PMID: 25176268]
  • E A Kartashova, M G Romantsov, I V Sarvilina. [The influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension]. Eksperimental'naia i klinicheskaia farmakologiia. 2014; 77(6):18-23. doi: ". [PMID: 25102730]
  • O A Vodop'ianova, I Ia Moiseeva, O P Rodina, I N Kustikova, N V Antropova. [The influence of cytoflavin and cardioxipin on the indices of lipid peroxidation and antioxidant protection in the blood of rat with dyslipidemia]. Eksperimental'naia i klinicheskaia farmakologiia. 2014; 77(6):27-9. doi: ". [PMID: 25102732]
  • N V Tsygan, A P Trashkov. [Brain functional state and cytoprotective potential in model of acute cerebral hypoxia (experimental research)]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 2013 Oct; ?(4):10-6. doi: NULL. [PMID: 24640767]
  • V V Shilov, A Iu Andrianov, S A Vasil'ev, Kh V Batotsyrenova, A T Loladze. [Pharmacological correction of hypoxia in patients with severe carbon monoxide poisoning]. Georgian medical news. 2012 Apr; ?(205):31-8. doi: ". [PMID: 22665729]
  • M G Romantsov, A Iu Petrov, L N Aleksandrova, D S Sukhanov, A L Kovalenko. [Pathogenetic correction of metabolic disturbances in chronic liver affections]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2012; 57(11-12):33-41. doi: ". [PMID: 23700935]
  • V A Kosinets, N N Iarotskaia. [Free-radical oxidation in liver during experimental widespread purulent peritonitis]. Eksperimental'naia i klinicheskaia farmakologiia. 2012; 75(10):37-41. doi: ". [PMID: 23240157]
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  • V A Kosinets, S S Osochuk, N N Iarotskaia. [Correction of protein-lipid composition in liver mitochondria during experimental widespread purulent peritonitis]. Eksperimental'naia i klinicheskaia farmakologiia. 2012; 75(3):31-4. doi: ". [PMID: 22679751]
  • V A Kosinets. [Metabolic correction of the lipid-transport system in experimental diffuse purulent peritonitis]. Vestnik khirurgii imeni I. I. Grekova. 2012; 171(3):92-6. doi: ". [PMID: 22880442]
  • A I Sazhin, M A Zaĭtseva, M E Melikhova, N F Ezhov, V B Sadovnikov, E V Navolotskaia. [Cardiotropic activity of synthetic peptide CH3CO-Lys-Lys-Arg-Arg-NH2 (protectin)]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(6):14-9. doi: . [PMID: 21870769]
  • N V Polutova, N V Ostrovskiĭ, M G Romantsov, N P Chesnokova. [Positive effect of cytoflavin on metabolic status changes in patients with burn disorder]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(7):33-7. doi: . [PMID: 21894767]
  • S O Rogatkin, N N Volodin, M G Degtiareva, O V Grebennikova, M Sh Marganiia, N D Serova. [Current approaches to cerebroprotective treatment of premature newborns in reanimation and intensive care departments]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2011; 111(1):27-32. doi: NULL. [PMID: 21350408]
  • I V Gordiushina, R P Savchenko, D S Sukhanov, A Iu Petrov, M G Romantsov. [Antioxidant and membranoprotector treatment of chronic pyelonephritis]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(4):27-30. doi: NULL. [PMID: 21678656]
  • E V Silina, S A Rumiantseva, S B Bolevich, N I Men'shova. [Course of free radical processes and prognosis of ischemic and hemorrhagic stroke]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2011; 111(12 Pt 2):36-42. doi: NULL. [PMID: 22792747]
  • G N Bisaga, M M Odinak, A N Boĭko, Iu B Mel'nik, N F Popova. [Possibilities of treatment of multiple sclerosis exacerbations without corticosteroids: a role of metabolic and antioxidant therapy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2011; 111(2):44-8. doi: ". [PMID: 21350423]
  • S V Tumanian, L G Ivanova. [Antioxidant protection as a component of anesthetic management cancer patients]. Khirurgiia. 2011; ?(6):66-9. doi: ". [PMID: 21716223]
  • S N Karpishchenko, S N Zheregelia, S I Glushkov. [Using cytoflavin for correcting x-ray contrasting agent-induced nephropathy]. Eksperimental'naia i klinicheskaia farmakologiia. 2010 Oct; 73(10):40-2. doi: NULL. [PMID: 21254514]
  • V V Poliakova, N H Raksha, L P Drahan, T R Andriĭchuk. [Effect of riboxine on processes of lipid peroxidation and activity of antioxidant enzymes in thymocytes of rats with radiation injury]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). 2010 Jul; 82(4):48-52. doi: ". [PMID: 21516716]
  • G A Livanov, V P Amagyrov, B V Batotsyrenov, A N Lodiagin, Kh V Batotsyrenova. [Pharmacological correction of hypoxic and free-radical disorders in patients with acute myocardial infarction complicated by acute heart failure]. Eksperimental'naia i klinicheskaia farmakologiia. 2010 May; 73(5):12-4. doi: ". [PMID: 20597363]
  • V A Kashuro, S I Glushkov, T M Novikova, V V Aksenov. [Cardioprotective effect of cytoflavine on a model of doxorubicin-induced cardiomyopathy]. Eksperimental'naia i klinicheskaia farmakologiia. 2010 Mar; 73(3):15-7. doi: ". [PMID: 20408423]
  • V A Kashuro, S I Glushkov, L V Minaeva, T M Novikova. [Experimental study on cytoflavin pharmacological correction of cyclophosphamide-induced toxic affections of the liver and kidneys]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2010; 55(9-10):29-32. doi: NULL. [PMID: 21400751]
  • S A Trofimova, O A Balunov, E E Dubinina. [Perspectives of treatment of patients with ischemic stroke: the place and the role of cytoflavin]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2010; 110(6):49-53. doi: . [PMID: 20559274]
  • V A Kosinets. [Antioxidant activity of cytoflavin in experimental diffuse purulent peritonitis]. Eksperimental'naia i klinicheskaia farmakologiia. 2010 Jan; 73(1):30-2. doi: ". [PMID: 20184286]
  • M V Aleksandrov, S A Vasil'ev, O A Kuznetsov, A Iu Andrianov, I A Shikalova, A T Loladze, B V Batotsyrenov. [The use of cytoflavin in combined neurometabolic therapy of acute cerebral insufficiency associated with acute poisoning with neurotropic poisons]. Klinicheskaia meditsina. 2010; 88(2):58-61. doi: ". [PMID: 21105475]
  • V A Kashuro, S I Glushkov, S N Zheregelia. [Cytoflavin in polychemotherapy of breast cancer]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 2010; 55(7-8):30-3. doi: ". [PMID: 21140562]
  • O N Pochepen'. [Efficacy of cytoflavin in the treatment of burns patients with toxic and post-hypoxic encephalopathy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2010; 110(10):23-9. doi: ". [PMID: 21183910]
  • G A Livanov, A N Lodiagin, I P Nikolaeva, B V Batotsyrenov. [The diagnosis and treatment of pulmonary hyperhydration in critically ill patients with acute poisoning by neurotropic agents]. Anesteziologiia i reanimatologiia. 2008 Nov; ?(6):27-30. doi: NULL. [PMID: 19227289]
  • K Yu Vasilyev, V A Khazanov. Effect of cerebronorm on energy metabolism and lipid peroxidation in rat brain during hypoxia. Bulletin of experimental biology and medicine. 2007 Nov; 144(5):695-8. doi: 10.1007/s10517-007-0408-0. [PMID: 18683499]
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  • V V Bul'on, N N Kuznetsova, E N Selina, A L Kovalenko, L E Alekseeva, N S Sapronov. Neuroprotective effect of cytoflavin during compression injury of the spinal cord. Bulletin of experimental biology and medicine. 2005 Apr; 139(4):394-6. doi: 10.1007/s10517-005-0303-5. [PMID: 16027862]
  • V V Bul'on, I V Zarubina, A L Kovalenko, L E Alekseeva, N S Sapronov. [Neuroprotective effect of cytoflavin in closed craniocerebral trauma]. Eksperimental'naia i klinicheskaia farmakologiia. 2003 Nov; 66(6):56-8. doi: ". [PMID: 14743715]
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  • V V Bul'on, L K Khnychenko, N S Sapronov, A L Kovalenko, L E Alekseeva. [Use of cytoflavin for correction of complications of myocardial infarction]. Eksperimental'naia i klinicheskaia farmakologiia. 2002 Jan; 65(1):27-9. doi: ". [PMID: 12025779]
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