4-Fluoro-L-phenylalanine (BioDeep_00000002902)

 

Secondary id: BioDeep_00001871908

human metabolite blood metabolite


代谢物信息卡片


2-amino-3-(4-fluorophenyl)propanoic acid

化学式: C9H10FNO2 (183.06955320000003)
中文名称: 4-氟-DL-苯丙氨酸, 对氟苯丙氨酸, 4-氟苯丙氨酸
谱图信息: 最多检出来源 Homo sapiens(blood) 97.48%

分子结构信息

SMILES: C1=CC(=CC=C1CC(C(=O)O)N)F
InChI: InChI=1S/C9H10FNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)

描述信息

同义名列表

15 个代谢物同义名

2-amino-3-(4-fluorophenyl)propanoic acid; 4-FLUORO-DL-PHENYLALANINE; p-Fluoro-DL-phenylalanine; Para-fluorophenylalanine; Para fluorophenylalanine; 4-Fluoro-L-phenylalanine; DL-p-Fluorophenylalanine; Fluorophenylalanine, p; DL-Fluorophenylalanine; 4 Fluorophenylalanine; p Fluorophenylalanine; p-Fluorophenylalanine; 4-Fluorophenylalanine; p-Fluorophenylalanine; 4-Fluorophenylalanine



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Bryan J Leong, Andrew D Hanson. Continuous Directed Evolution of a Feedback-Resistant Arabidopsis Arogenate Dehydratase in Plantized Escherichia coli. ACS synthetic biology. 2023 01; 12(1):43-50. doi: 10.1021/acssynbio.2c00511. [PMID: 36534785]
  • O V Zimina, M F Parii, O G Alkhimova. Title Not Available. TSitologiia i genetika. 2016 Sep; 50(5):17-24. doi: ". [PMID: 30480912]
  • Karen M E Dierickx, Renato Morandini, Thi Hien Nguyen, François Salès, Jean-Michel Kauffmann, Ghanem E Ghanem. A novel transport and delivery mechanism underpins the effectiveness of prolyl-m-sarcolysyl-p-fluorophenylalanine (PSF) in a human melanoma xenograft nude-mouse model. Pigment cell & melanoma research. 2008 Aug; 21(4):439-50. doi: 10.1111/j.1755-148x.2008.00471.x. [PMID: 18627526]
  • K V Kiselev, A S Dubrovina, M V Veselova, V P Bulgakov, S A Fedoreyev, Y N Zhuravlev. The rolB gene-induced overproduction of resveratrol in Vitis amurensis transformed cells. Journal of biotechnology. 2007 Feb; 128(3):681-92. doi: 10.1016/j.jbiotec.2006.11.008. [PMID: 17166613]
  • H Kloosterman, G I Hessels, J W Vrijbloed, G J Euverink, L Dijkhuizen. (De)regulation of key enzyme steps in the shikimate pathway and phenylalanine-specific pathway of the actinomycete Amycolatopsis methanolica. Microbiology (Reading, England). 2003 Nov; 149(Pt 11):3321-3330. doi: 10.1099/mic.0.26494-0. [PMID: 14600244]
  • V P Bulgakov, M M Kozyrenko, S A Fedoreyev, N P Mischenko, V A Denisenko, L V Zvereva, T V Pokushalova, Y N Zhuravlev. Shikonin production by p-fluorophenylalanine resistant cells of Lithospermum erythrorhizon. Fitoterapia. 2001 May; 72(4):394-401. doi: 10.1016/s0367-326x(00)00343-9. [PMID: 11395262]
  • N Babudri, G Morpurgo. Frequency of spontaneous and induced recessive mutations in a diploid strain of Aspergillus nidulans. Mutation research. 1990 Jun; 230(2):187-95. doi: 10.1016/0027-5107(90)90056-a. [PMID: 2197553]
  • N Babudri, G Morpurgo. p-fluoro-phenylalanine resistance in Aspergillus nidulans diploid cells: evidence that dominant, lethal mutations are involved. Current genetics. 1990 Jun; 17(6):519-22. doi: 10.1007/bf00313081. [PMID: 2202526]
  • V Shakespeare, J H Buchanan. Studies on phosphoglucose isomerase from cultured human fibroblasts: absence of detectable ageing effects on the enzyme. Journal of cellular physiology. 1978 Jan; 94(1):105-15. doi: 10.1002/jcp.1040940114. [PMID: 618901]
  • W E Timberlake. Alterations in RNA and protein synthesis associated with steroid hormone-induced sexual morphogenesis in the water mold Achlya. Developmental biology. 1976 Jul; 51(2):202-14. doi: 10.1016/0012-1606(76)90138-x. [PMID: 955256]
  • K D Munkres. Ageing of Neurospora crassa. IV. Induction of senescence in wild type by dietary amino acid analogs and reversal by antioxidants and membrane stabilizers. Mechanisms of ageing and development. 1976 May; 5(3):171-91. doi: 10.1016/0047-6374(76)90017-8. [PMID: 7715]
  • J P Jouanneau. Protein synthesis requirement for the cytokinin effect upon tobacco cell division. Experimental cell research. 1975 Mar; 91(1):184-90. doi: 10.1016/0014-4827(75)90156-1. [PMID: 1132416]
  • J C SEIDEL, A E HARPER. DIET AND CHOLESTEROLEMIA. VII. EFFECTS OF METHIONINE, ETHIONINE, AND P-FLUOROPHENYLALANINE. Journal of lipid research. 1963 Jan; 4(?):75-80. doi: . [PMID: 14167669]