Diketopiperazine (BioDeep_00000002859)
Secondary id: BioDeep_00001868181
代谢物信息卡片
化学式: C4H6N2O2 (114.04292559999999)
中文名称: 甘氨酸酐
谱图信息:
最多检出来源 Macaca mulatta(otcml) 3.19%
分子结构信息
SMILES: C1C(=O)NCC(=O)N1
InChI: InChI=1S/C4H6N2O2/c7-3-1-5-4(8)2-6-3/h1-2H2,(H,5,8)(H,6,7)
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D054659 - Diketopiperazines
同义名列表
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:16535
- KEGG: C02777
- PubChem: 7817
- Metlin: METLIN65826
- ChEMBL: CHEMBL125229
- CAS: 106-57-0
- PMhub: MS000006702
- PubChem: 5728
- KNApSAcK: C00014894
- 3DMET: B00497
- NIKKAJI: J4.036C
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Zhuo-Zheng Xu, Zheng Zhuang, Runlin Cai, Guo-Qiang Lin, Zhigang She, Qunfei Zhao, Qing-Li He. Hydroxylation with Unusual Stereoinversion Catalyzed by an FeII /2-OG Dependent Oxidase and 3,6-Diene-2,5-diketopiperazine Formation in the Biosynthesis of Brevianamide K.
Angewandte Chemie (International ed. in English).
2023 Feb; ?(?):e202216989. doi:
10.1002/anie.202216989. [PMID: 36750406] - Dan-Yu Huang, Xu-Hua Nong, Yu-Qin Zhang, Wei Xu, Long-Yu Sun, Tao Zhang, Guang-Ying Chen, Chang-Ri Han. Two new 2,5-diketopiperazine derivatives from mangrove-derived endophytic fungus Nigrospora camelliae-sinensis S30.
Natural product research.
2022 Jul; 36(14):3651-3656. doi:
10.1080/14786419.2021.1878168. [PMID: 33517796] - Paweł J Andruszkiewicz, Roy N D'Souza, Irem Altun, Marcello Corno, Nikolai Kuhnert. Thermally-induced formation of taste-active 2,5-diketopiperazines from short-chain peptide precursors in cocoa.
Food research international (Ottawa, Ont.).
2019 07; 121(?):217-228. doi:
10.1016/j.foodres.2019.03.015. [PMID: 31108743] - Ming Yang, Jianghe Luo, Zhumei Zeng, Ling Yang, Limian Xu, Yan Li. In silico profiling the interaction mechanism of 2,5-diketopiperazine derivatives as oxytocin antagonists.
Journal of molecular graphics & modelling.
2019 06; 89(?):178-191. doi:
10.1016/j.jmgm.2019.03.003. [PMID: 30904734] - Guangde Jiang, Yi Zhang, Magan M Powell, Sarah M Hylton, Nicholas W Hiller, Rosemary Loria, Yousong Ding. A Promiscuous Cytochrome P450 Hydroxylates Aliphatic and Aromatic C-H Bonds of Aromatic 2,5-Diketopiperazines.
Chembiochem : a European journal of chemical biology.
2019 04; 20(8):1068-1077. doi:
10.1002/cbic.201800736. [PMID: 30604585] - Hiroshi Ashigai, Yoshimasa Taniguchi, Yasuko Matsukura, Emiko Ikeshima, Keiko Nakashima, Mai Mizutani, Hiroaki Yajima. Roasted Barley Extract Affects Blood Flow in the Rat Tail and Increases Cutaneous Blood Flow and Skin Temperature in Humans.
Journal of agricultural and food chemistry.
2018 Feb; 66(5):1251-1257. doi:
10.1021/acs.jafc.7b04930. [PMID: 29338262] - Susan Weng Larsen, Michael Ankersen, Claus Larsen. Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2004 Aug; 22(5):399-408. doi:
10.1016/j.ejps.2004.04.013. [PMID: 15265509] - J Haginaka, J Wakai. A sensitive high performance liquid chromatographic assay of a new metabolite of ampicillin in man.
The Journal of pharmacy and pharmacology.
1986 Mar; 38(3):225-6. doi:
10.1111/j.2042-7158.1986.tb04551.x. [PMID: 2871162]