D-sorbose (BioDeep_00000271463)

Main id: BioDeep_00000002391

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


1,3,4,5,6-pentahydroxyhexan-2-one

化学式: C6H12O6 (180.0634)
中文名称: 山梨糖
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C(C(C(=O)CO)O)O)O)O
InChI: InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5+,6+/m1/s1

描述信息

同义名列表

5 个代谢物同义名

D-(−)-Fructose; D-sorbose; 1,3,4,5,6-pentahydroxyhexan-2-one; D-Sorbose; Sorbose



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

39 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ALB, MAPK8, PFDN5, TXNIP
Peripheral membrane protein 1 SORD
Mitochondrion membrane 1 SORD
Nucleus 3 ALB, MAPK8, PFDN5
cytosol 6 ALB, APOA1, MAPK8, PFDN5, SORD, TXNIP
mitochondrial membrane 1 SORD
centrosome 1 ALB
nucleoplasm 1 MAPK8
Cell membrane 1 TREH
Synapse 1 MAPK8
cell surface 3 ADIPOQ, MBL2, TNR
glutamatergic synapse 1 TNR
Golgi apparatus 1 ALB
Golgi membrane 1 INS
plasma membrane 3 APOA1, LCT, TREH
Membrane 2 SORD, TREH
axon 1 MAPK8
extracellular exosome 4 ALB, APOA1, SORD, TREH
endoplasmic reticulum 2 ADIPOQ, ALB
extracellular space 7 ADIPOQ, ALB, APOA1, INS, MBL2, SORD, TNR
Schaffer collateral - CA1 synapse 1 TNR
protein-containing complex 1 ALB
Single-pass type I membrane protein 1 LCT
Secreted 5 ADIPOQ, ALB, APOA1, INS, MBL2
extracellular region 6 ADIPOQ, ALB, APOA1, INS, MBL2, TNR
anchoring junction 1 ALB
motile cilium 1 SORD
external side of plasma membrane 1 MBL2
Extracellular vesicle 1 APOA1
Secreted, extracellular space, extracellular matrix 1 TNR
chylomicron 1 APOA1
high-density lipoprotein particle 1 APOA1
low-density lipoprotein particle 1 APOA1
multivesicular body 1 MBL2
very-low-density lipoprotein particle 1 APOA1
cytoplasmic vesicle 1 APOA1
Early endosome 1 APOA1
Apical cell membrane 1 LCT
Membrane raft 1 TNR
collagen trimer 2 ADIPOQ, MBL2
collagen-containing extracellular matrix 3 ADIPOQ, APOA1, TNR
ciliary basal body 1 ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 2 ALB, APOA1
Cell projection, cilium, flagellum 1 SORD
Lipid-anchor, GPI-anchor 1 TREH
endosome lumen 1 INS
side of membrane 1 TREH
intermediate filament cytoskeleton 1 PFDN5
secretory granule lumen 2 APOA1, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 3 ALB, APOA1, INS
platelet alpha granule lumen 1 ALB
endocytic vesicle 1 APOA1
transport vesicle 1 INS
serine-type endopeptidase complex 1 MBL2
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
perineuronal net 1 TNR
prefoldin complex 1 PFDN5
external side of apical plasma membrane 1 LCT
basal dendrite 1 MAPK8
spherical high-density lipoprotein particle 1 APOA1
endocytic vesicle lumen 1 APOA1
tenascin complex 1 TNR
ciliary transition fiber 1 ALB


文献列表

  • Yasuo Nagata, Narumi Mizuta, Akane Kanasaki, Kazunari Tanaka. Rare sugars, d-allulose, d-tagatose and d-sorbose, differently modulate lipid metabolism in rats. Journal of the science of food and agriculture. 2018 Mar; 98(5):2020-2026. doi: 10.1002/jsfa.8687. [PMID: 28940418]
  • Tadashi Sato, Shiro Kusuhara, Wakae Yokoi, Masahiko Ito, Kouji Miyazaki. Prebiotic potential of L-sorbose and xylitol in promoting the growth and metabolic activity of specific butyrate-producing bacteria in human fecal culture. FEMS microbiology ecology. 2017 01; 93(1):. doi: 10.1093/femsec/fiw227. [PMID: 27810878]
  • M T Ortega, B Jeffery, J E Riviere, N A Monteiro-Riviere. Toxicological effects of pet food ingredients on canine bone marrow-derived mesenchymal stem cells and enterocyte-like cells. Journal of applied toxicology : JAT. 2016 Feb; 36(2):189-98. doi: 10.1002/jat.3158. [PMID: 25976427]
  • J Koči, B Jeffery, J E Riviere, N A Monteiro-Riviere. In vitro safety assessment of food ingredients in canine renal proximal tubule cells. Toxicology in vitro : an international journal published in association with BIBRA. 2015 Mar; 29(2):289-98. doi: 10.1016/j.tiv.2014.11.002. [PMID: 25458622]
  • Takako Yamada, Noriko Hayashi, Tetsuo Iida, Satoshi Takamine, Kazuhiro Okuma, Tatsuhiro Matsuo. Dietary D-sorbose decreases serum insulin levels in growing Sprague-Dawley rats. Journal of nutritional science and vitaminology. 2014; 60(4):297-9. doi: 10.3177/jnsv.60.297. [PMID: 25297620]
  • Yun Gao, Ying-Jin Yuan. Comprehensive quality evaluation of corn steep liquor in 2-keto-L-gulonic acid fermentation. Journal of agricultural and food chemistry. 2011 Sep; 59(18):9845-53. doi: 10.1021/jf201792u. [PMID: 21793578]
  • D Spadaro, A Ciavorella, Z Dianpeng, A Garibaldi, M L Gullino. Effect of culture media and pH on the biomass production and biocontrol efficacy of a Metschnikowia pulcherrima strain to be used as a biofungicide for postharvest disease control. Canadian journal of microbiology. 2010 Feb; 56(2):128-37. doi: 10.1139/w09-117. [PMID: 20237574]
  • Akihito Kano, Kenji Gomi, Yumiko Yamasaki-Kokudo, Masaru Satoh, Takeshi Fukumoto, Kouhei Ohtani, Shigeyuki Tajima, Ken Izumori, Keiji Tanaka, Yutaka Ishida, Yasuomi Tada, Yoko Nishizawa, Kazuya Akimitsu. A rare sugar, d-allose, confers resistance to rice bacterial blight with upregulation of defense-related genes in Oryza sativa. Phytopathology. 2010 Jan; 100(1):85-90. doi: 10.1094/phyto-100-1-0085. [PMID: 19968553]
  • Anselm Lehmacher, Jochen Bockemühl. L-Sorbose utilization by virulent Escherichia coli and Shigella: different metabolic adaptation of pathotypes. International journal of medical microbiology : IJMM. 2007 Jul; 297(4):245-54. doi: 10.1016/j.ijmm.2007.01.007. [PMID: 17382590]
  • A Xu, J Yao, L Yu, S Lv, J Wang, B Yan, Z Yu. Mutation of Gluconobacter oxydans and Bacillus megaterium in a two-step process of l-ascorbic acid manufacture by ion beam. Journal of applied microbiology. 2004; 96(6):1317-23. doi: 10.1111/j.1365-2672.2004.02270.x. [PMID: 15139924]
  • Yoshimitsu Takakura, Shigeru Kuwata. Purification, characterization, and molecular cloning of a pyranose oxidase from the fruit body of the basidiomycete, Tricholoma matsutake. Bioscience, biotechnology, and biochemistry. 2003 Dec; 67(12):2598-607. doi: 10.1271/bbb.67.2598. [PMID: 14730138]
  • Elena Vittadini, L Charles Dickinson, James P Lavoie, Xuyen Pham, Pavinee Chinachoti. Water mobility in multicomponent model media as studied by 2H and 17O NMR. Journal of agricultural and food chemistry. 2003 Mar; 51(6):1647-52. doi: 10.1021/jf020730l. [PMID: 12617599]
  • A B Din, C A Specht, P W Robbins, O Yarden. chs-4, a class IV chitin synthase gene from Neurospora crassa. Molecular & general genetics : MGG. 1996 Feb; 250(2):214-22. doi: 10.1007/bf02174181. [PMID: 8628221]
  • O Grishina, G Charpin, F Marquet, D Pansu, M Descroix-Vagne. [Effect of C-terminal derivatives of sorbin on duodenal ion transports in rats]. Gastroenterologie clinique et biologique. 1995 May; 19(5):487-93. doi: NULL. [PMID: 7590000]
  • M Furuse, C Kimura, H Takahashi, J Okumura. Influence of dietary sorbose on diabetes in nonobese diabetic mice. Comparative biochemistry and physiology. Comparative physiology. 1994 May; 108(1):123-7. doi: . [PMID: 7915649]
  • R J Comi, H Hamilton. Reduction of red cell glucose transporter intrinsic activity in diabetes running. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 1994 Jan; 26(1):26-32. doi: 10.1055/s-2007-1000767. [PMID: 8150420]
  • M Furuse, C Kimura, R T Mabayo, H Takahashi, J Okumura. Dietary sorbose prevents and improves hyperglycemia in genetically diabetic mice. The Journal of nutrition. 1993 Jan; 123(1):59-65. doi: 10.1093/jn/123.1.59. [PMID: 8421231]
  • R S Beyer, L S Jensen. Reduced plasma cholesterol and lipoprotein in laying hens without concomitant reduction of egg cholesterol in response to dietary sorbose. Poultry science. 1993 Jan; 72(1):88-97. doi: 10.3382/ps.0720088. [PMID: 8426850]
  • K Kita, M Furuse, S I Yang, J Okumura. Influence of dietary sorbose on lipogenesis in gold thioglucose-injected obese mice. The International journal of biochemistry. 1992 Feb; 24(2):249-53. doi: 10.1016/0020-711x(92)90254-x. [PMID: 1733790]
  • M Furuse, C Kimura, H Takahashi, J Okumura. Prevention of the incidence of diabetes by dietary sorbose in nonobese diabetic mice. The Journal of nutrition. 1991 Jul; 121(7):1135-8. doi: 10.1093/jn/121.7.1135. [PMID: 2051234]
  • M Furuse, S I Yang, N Niwa, Y H Choi, J Okumura. Energy utilisation in germ-free and conventional chicks fed diets containing sorbose. British poultry science. 1991 May; 32(2):383-90. doi: 10.1080/00071669108417363. [PMID: 1868376]
  • M Furuse, T Ishii, S Miyagawa, J Nakagawa, T Shimizu, T Watanabe, J Okumura. Effect of dietary sorbose on lipid metabolism in male and female broilers. Poultry science. 1991 Jan; 70(1):95-102. doi: 10.3382/ps.0700095. [PMID: 2017422]
  • M Furuse, S Nakajima, J Nakagawa, T Shimizu, J Okumura. Regulation of lipid metabolism by dietary sorbose in laying hens. Poultry science. 1990 Sep; 69(9):1508-12. doi: 10.3382/ps.0691508. [PMID: 2247413]
  • M Furuse, Y Tamura, S Matsuda, T Shimizu, J Okumura. Lower fat deposition and energy utilization of growing rats fed diets containing sorbose. Comparative biochemistry and physiology. A, Comparative physiology. 1989; 94(4):813-7. doi: 10.1016/0300-9629(89)90640-3. [PMID: 2575967]
  • P Würsch, C Welsch, M J Arnaud. Metabolism of L-sorbose in the rat and the effect of the intestinal microflora on its utilization both in the rat and in the human. Nutrition and metabolism. 1979; 23(3):145-55. doi: 10.1159/000176251. [PMID: 424083]
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