Isoformononetin (BioDeep_00000270348)

Main id: BioDeep_00000396964

 

PANOMIX_OTCML-2023


代谢物信息卡片


4H-1-Benzopyran-4-one, 3-(4-hydroxyphenyl)-7-methoxy-

化学式: C16H12O4 (268.0735552)
中文名称: 3-(4-羟基苯基)-7-甲氧基-4H-色烯-4-酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COc(c3)cc(O2)c(c3)C(=O)C(=C2)c(c1)ccc(O)c1
InChI: InChI=1S/C16H12O4/c1-19-12-6-7-13-15(8-12)20-9-14(16(13)18)10-2-4-11(17)5-3-10/h2-9,17H,1H3

描述信息

Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions[1].
Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions[1].

同义名列表

11 个代谢物同义名

4H-1-Benzopyran-4-one, 3-(4-hydroxyphenyl)-7-methoxy-; 3-(4-hydroxyphenyl)-7-methoxy-chromen-4-one; 3-(4-hydroxyphenyl)-7-methoxy-4-chromenone; 3-(4-hydroxyphenyl)-7-methoxychromen-4-one; 3-(4-hydroxyphenyl)-7-methoxy-chromone; 7-methoxy-4-hydroxyisoflavone; 4-hydroxy-7-methoxyisoflavone; Isoformononetin; C12125; HMO; 3- (4-Hydroxyphenyl) -7-methoxy-4H-1-benzopyran-4-one



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

10 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Swati Chaturvedi, Virendra Tiwari, Narwade Mahaveer Gangadhar, Mamunur Rashid, Nazneen Sultana, Sandeep Kumar Singh, Shubha Shukla, Muhammad Wahajuddin. Isoformononetin, a dietary isoflavone protects against streptozotocin induced rat model of neuroinflammation through inhibition of NLRP3/ASC/IL-1 axis activation. Life sciences. 2021 Dec; 286(?):119989. doi: 10.1016/j.lfs.2021.119989. [PMID: 34597609]
  • Rashmi Pandey, Abnish K Gautam, Biju Bhargavan, Ritu Trivedi, Gaurav Swarnkar, Geet K Nagar, Dinesh K Yadav, Manmeet Kumar, Preeti Rawat, Lakshmi Manickavasagam, Amit Kumar, Rakesh Maurya, Atul Goel, Girish K Jain, Naibedya Chattopadhyay, Divya Singh. Total extract and standardized fraction from the stem bark of Butea monosperma have osteoprotective action: evidence for the nonestrogenic osteogenic effect of the standardized fraction. Menopause (New York, N.Y.). 2010 May; 17(3):602-10. doi: 10.1097/gme.0b013e3181d0f7f0. [PMID: 20395887]
  • Rakesh Maurya, Dinesh K Yadav, Geetu Singh, Biju Bhargavan, P S Narayana Murthy, Mahendra Sahai, Man Mohan Singh. Osteogenic activity of constituents from Butea monosperma. Bioorganic & medicinal chemistry letters. 2009 Feb; 19(3):610-3. doi: 10.1016/j.bmcl.2008.12.064. [PMID: 19124244]
  • Evans Kaimoyo, Hans D VanEtten. Inactivation of pea genes by RNAi supports the involvement of two similar O-methyltransferases in the biosynthesis of (+)-pisatin and of chiral intermediates with a configuration opposite that found in (+)-pisatin. Phytochemistry. 2008 Jan; 69(1):76-87. doi: 10.1016/j.phytochem.2007.06.013. [PMID: 17707445]
  • K C Luk, L Stern, M Weigele, R A O'Brien, N Spirt. Isolation and identification of 'diazepam-like' compounds from bovine urine. Journal of natural products. 1983 Nov; 46(6):852-61. doi: 10.1021/np50030a005. [PMID: 6330305]