Melatonin (BioDeep_00000269410)

Main id: BioDeep_00000000216

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide

化学式: C13H16N2O2 (232.1212)
中文名称: 褪黑素
谱图信息: 最多检出来源 Homo sapiens(blood) 35.89%

分子结构信息

SMILES: c12c(cc(cc1)OC)c(c[nH]2)CCNC(=O)C
InChI: InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)

描述信息

N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives > N05CH - Melatonin receptor agonists
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone
D020011 - Protective Agents > D000975 - Antioxidants
C26170 - Protective Agent > C275 - Antioxidant
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
ORIGINAL_PRECURSOR_SCAN_NO 3385; CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3387
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3387; ORIGINAL_PRECURSOR_SCAN_NO 3385
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3400; ORIGINAL_PRECURSOR_SCAN_NO 3398
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3376; ORIGINAL_PRECURSOR_SCAN_NO 3375
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3184; ORIGINAL_PRECURSOR_SCAN_NO 3183
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3391; ORIGINAL_PRECURSOR_SCAN_NO 3387
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3198; ORIGINAL_PRECURSOR_SCAN_NO 3196
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7086; ORIGINAL_PRECURSOR_SCAN_NO 7084
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7064; ORIGINAL_PRECURSOR_SCAN_NO 7062
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7062; ORIGINAL_PRECURSOR_SCAN_NO 7059
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7093; ORIGINAL_PRECURSOR_SCAN_NO 7090
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7098; ORIGINAL_PRECURSOR_SCAN_NO 7096
CONFIDENCE standard compound; INTERNAL_ID 961; DATASET 20200303_ENTACT_RP_MIX502; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7084; ORIGINAL_PRECURSOR_SCAN_NO 7082
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.685
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.686
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.679
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.682
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].
Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties[1][2][3]. Melatonin is a novel selective ATF-6 inhibitor and induces human hepatoma cell apoptosis through COX-2 downregulation[4]. Melatonin attenuates palmitic acid-induced (HY-N0830) mouse granulosa cells apoptosis via endoplasmic reticulum stress[5].

同义名列表

6 个代谢物同义名

Melatonine; Melatonin; N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide; N-Acetyl-5-methoxytryptamine; Melatonin; Melatonin



数据库引用编号

127 个数据库交叉引用编号

分类词条

75 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 BCL2, BMAL2, NFE2L2, NR3C1, PRL
Endoplasmic reticulum membrane 1 BCL2
Nucleus 8 BCL2, BHLHE41, BMAL2, FOS, NFE2L2, NFIL3, NR3C1, PRL
cytosol 5 BCL2, FOS, NFE2L2, NR3C1, SST
centrosome 2 NFE2L2, NR3C1
nucleoplasm 6 BMAL2, FOS, GPR50, NFE2L2, NR3C1, PRL
RNA polymerase II transcription regulator complex 4 FOS, NFE2L2, NFIL3, PRL
Cell membrane 2 GPR50, TNF
Multi-pass membrane protein 1 GPR50
Synapse 2 CRH, NR3C1
cell surface 1 TNF
Golgi apparatus 2 NFE2L2, NPY
neuronal cell body 3 KISS1, SST, TNF
Cytoplasm, cytosol 1 NFE2L2
plasma membrane 5 GCG, GPR50, NFE2L2, REN, TNF
Membrane 3 BCL2, NR3C1, REN
apical plasma membrane 1 KISS1
endoplasmic reticulum 2 BCL2, FOS
extracellular space 11 CRH, GCG, GNRH1, IGF1, IL2, KISS1, NPY, PRL, REN, SST, TNF
mitochondrion 2 BCL2, NR3C1
protein-containing complex 2 BCL2, NR3C1
postsynaptic density 1 GPR50
Secreted 9 ADCYAP1, CRH, GCG, IGF1, IL2, NPY, PRL, REN, SST
extracellular region 12 ADCYAP1, CRH, GCG, GNRH1, IGF1, IL2, KISS1, NPY, PRL, REN, SST, TNF
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
mitochondrial matrix 1 NR3C1
transcription regulator complex 1 BMAL2
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 NR3C1
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 1 TNF
varicosity 1 CRH
neuronal dense core vesicle lumen 1 CRH
perikaryon 2 ADCYAP1, CRH
nucleolus 1 BMAL2
apical part of cell 1 REN
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 1 TNF
pore complex 1 BCL2
Cytoplasm, cytoskeleton, spindle 1 NR3C1
spindle 1 NR3C1
GABA-ergic synapse 2 NPY, SST
nuclear speck 1 NR3C1
neuron projection 1 ADCYAP1
chromatin 7 BHLHE41, BMAL2, FOS, NFE2L2, NFIL3, NR3C1, PRL
mediator complex 1 NFE2L2
phagocytic cup 1 TNF
Chromosome 1 NR3C1
endosome lumen 1 PRL
aryl hydrocarbon receptor complex 1 BMAL2
Nucleus, nucleoplasm 1 NR3C1
myelin sheath 1 BCL2
exocytic vesicle 1 IGF1
secretory granule lumen 1 GCG
endoplasmic reticulum lumen 1 GCG
nuclear matrix 1 FOS
platelet alpha granule lumen 1 IGF1
CLOCK-BMAL transcription complex 1 BMAL2
neuronal dense core vesicle 2 NPY, SST
protein-DNA complex 2 FOS, NFE2L2
[Isoform Alpha]: Cytoplasm 1 NR3C1
transcription factor AP-1 complex 1 FOS
[Glucagon-like peptide 1]: Secreted 1 GCG
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
[Isoform Beta]: Nucleus 1 NR3C1
[Isoform Alpha-B]: Nucleus 1 NR3C1
alphav-beta3 integrin-IGF-1-IGF1R complex 1 IGF1
insulin-like growth factor binding protein complex 1 IGF1
insulin-like growth factor ternary complex 1 IGF1
BAD-BCL-2 complex 1 BCL2
[C-terminal domain]: Nucleus 1 GPR50
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Zhongyi Yang, Xixi Yang, Shimei Wei, Fengfeng Shen, Wei Ji. Exogenous melatonin delays leaves senescence and enhances saline and alkaline stress tolerance in grape seedlings. Plant signaling & behavior. 2024 Dec; 19(1):2334511. doi: 10.1080/15592324.2024.2334511. [PMID: 38650457]
  • Faisal Zulfiqar, Anam Moosa, Hayssam M Ali, John T Hancock, Jean Wan Hong Yong. Synergistic interplay between melatonin and hydrogen sulfide enhances cadmium-induced oxidative stress resistance in stock (Matthiola incana L.). Plant signaling & behavior. 2024 Dec; 19(1):2331357. doi: 10.1080/15592324.2024.2331357. [PMID: 38564424]
  • Quan Gu, Chenyang Xie, Song Zhang, Tingyan Zhou, Na Li, Congshan Xu, Zhou Zhou, Chuyan Wang, Ziping Chen. Transcriptomic analysis provides insights into the molecular mechanism of melatonin-mediated cadmium tolerance in Medicago sativa L. Ecotoxicology and environmental safety. 2024 Jun; 278(?):116411. doi: 10.1016/j.ecoenv.2024.116411. [PMID: 38714085]
  • Gaoxuan Shao, Ying Liu, Lu Lu, Lei Wang, Guang Ji, Hanchen Xu. Therapeutic potential of traditional Chinese medicine in the prevention and treatment of digestive inflammatory cancer transformation: Portulaca oleracea L. as a promising drug. Journal of ethnopharmacology. 2024 Jun; 327(?):117999. doi: 10.1016/j.jep.2024.117999. [PMID: 38447616]
  • Aline de Camargo Santos, Bruce Schaffer, Andreas G Ioannou, Pamela Moon, Muhammad Shahid, Diane Rowland, Barry Tillman, Matthew Bremgartner, Vasileios Fotopoulos, Elias Bassil. Melatonin seed priming improves early establishment and water stress tolerance of peanut. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108664. doi: 10.1016/j.plaphy.2024.108664. [PMID: 38703498]
  • Guangdong Li, Laiqing Yan, Likai Wang, Wenkui Ma, Hao Wu, Shengyu Guan, Yujun Yao, Shoulong Deng, Hai Yang, Jinlong Zhang, Xiaosheng Zhang, Haixin Wu, Changjiu He, Pengyun Ji, Zhengxing Lian, Yingjie Wu, Lu Zhang, Guoshi Liu. Ovarian overexpression of ASMT gene increases follicle numbers in transgenic sheep: Association with lipid metabolism. International journal of biological macromolecules. 2024 Jun; 269(Pt 2):131803. doi: 10.1016/j.ijbiomac.2024.131803. [PMID: 38670205]
  • Muhammad Imran Ghani, Benlin Yi, Muhammad Saad Rehmani, Xi Wei, Junaid Ali Siddiqui, Ruidong Fan, Yanjiang Liu, Mohamed A El-Sheikh, Xiaoyulong Chen, Parvaiz Ahmad. Potential of melatonin and Trichoderma harzianum inoculation in ameliorating salt toxicity in watermelon: Insights into antioxidant system, leaf ultrastructure, and gene regulation. Plant physiology and biochemistry : PPB. 2024 Jun; 211(?):108639. doi: 10.1016/j.plaphy.2024.108639. [PMID: 38688113]
  • Yangyang Tao, Qinglong Zhao, Chengbo Lu, Weilin Yong, Mingyuan Xu, Zhuo Wang, Xiaoping Leng. Melatonin suppresses atherosclerosis by ferroptosis inhibition via activating NRF2 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2024 May; 38(10):e23678. doi: 10.1096/fj.202400427rr. [PMID: 38780199]
  • Tian-Ji Xia, Su-Wei Jin, Yong-Guang Liu, Shan-Shan Zhang, Zhi Wang, Xin-Min Liu, Rui-Le Pan, Ning Jiang, Yong-Hong Liao, Ming-Zhu Yan, Qi Chang. Shen Yuan extract exerts a hypnotic effect via the tryptophan/5-hydroxytryptamine/melatonin pathway in mice. Journal of ethnopharmacology. 2024 May; 326(?):117992. doi: 10.1016/j.jep.2024.117992. [PMID: 38428654]
  • Ihsan Muhammad, Fahim Ullah, Shakeel Ahmad, Bandar M AlMunqedhi, Dunia A Al Farraj, Mohamed S Elshikh, Weijun Shen. A meta-analysis of photosynthetic efficiency and stress mitigation by melatonin in enhancing wheat tolerance. BMC plant biology. 2024 May; 24(1):427. doi: 10.1186/s12870-024-05132-2. [PMID: 38769501]
  • Shirin Rahmanzadeh-Ishkeh, Habib Shirzad, Zahra Tofighi, Mohammad Fattahi, Youbert Ghosta. Exogenous melatonin prolongs raspberry postharvest life quality by increasing some antioxidant and enzyme activity and phytochemical contents. Scientific reports. 2024 05; 14(1):11508. doi: 10.1038/s41598-024-62111-1. [PMID: 38769439]
  • Masoomeh Nabaei, Rayhaneh Amooaghaie, Mansour Ghorbanpour, Alimohammad Ahadi. Crosstalk between melatonin and nitric oxide restrains Cadmium-induced oxidative stress and enhances vinblastine biosynthesis in Catharanthus roseus (L) G Don. Plant cell reports. 2024 May; 43(6):139. doi: 10.1007/s00299-024-03229-4. [PMID: 38735908]
  • Yajuan Duan, Xianxu Wang, Yan Jiao, Yangyang Liu, Yue Li, Yongze Song, Lei Wang, Xiaohong Tong, Yan Jiang, Shaodong Wang, Sui Wang. Elucidating the role of exogenous melatonin in mitigating alkaline stress in soybeans across different growth stages: a transcriptomic and metabolomic approach. BMC plant biology. 2024 May; 24(1):380. doi: 10.1186/s12870-024-05101-9. [PMID: 38720246]
  • Nanqin Mei, Jingwen Liang, Danielle M McRae, Zoya Leonenko. Localized surface plasmon resonance and atomic force microscopy study of model lipid membranes and their interactions with amyloid and melatonin. Nanotechnology. 2024 May; 35(30):. doi: 10.1088/1361-6528/ad403b. [PMID: 38636478]
  • Yuanyuan Fu, Penghui Li, Zhuanyun Si, Shoutian Ma, Yang Gao. Seeds Priming with Melatonin Improves Root Hydraulic Conductivity of Wheat Varieties under Drought, Salinity, and Combined Stress. International journal of molecular sciences. 2024 May; 25(9):. doi: 10.3390/ijms25095055. [PMID: 38732273]
  • Guohui Li, Muhammad Aamir Manzoor, Guoyu Wang, Shiping Huang, Xiaoyuan Ding, Muhammad Abdullah, Ming Zhang, Cheng Song. Comparative analysis of POD genes and their expression under multiple hormones in Pyrus bretschenedri. BMC genomic data. 2024 May; 25(1):41. doi: 10.1186/s12863-024-01229-7. [PMID: 38711007]
  • Yuanyuan Li, Congcong Zhang, Xu Lu, Haokai Yan, Guojie Nai, Meishuang Gong, Ying Lai, Zhihui Pu, Li Wei, Shaoying Ma, Sheng Li. Impact of exogenous melatonin foliar application on physiology and fruit quality of wine grapes (Vitis vinifera) under salt stress. Functional plant biology : FPB. 2024 05; 51(?):. doi: 10.1071/fp24019. [PMID: 38743838]
  • Davood Dorranipour, Fahimeh Pourjafari, Reza Malekpour-Afshar, Mohsen Basiri, Mehran Hosseini. Assessment of melatonin's therapeutic effectiveness against hepatic steatosis induced by a high-carbohydrate high-fat diet in rats. Naunyn-Schmiedeberg's archives of pharmacology. 2024 05; 397(5):2971-2985. doi: 10.1007/s00210-023-02784-z. [PMID: 37864588]
  • Qingyun Guan, Zixu Wang, Jing Cao, Yulan Dong, Shusheng Tang, Yaoxing Chen. Melatonin restores hepatic lipid metabolic homeostasis disrupted by blue light at night in high-fat diet-fed mice. Journal of pineal research. 2024 May; 76(4):e12963. doi: 10.1111/jpi.12963. [PMID: 38779971]
  • Etienne Challet, Paul Pévet. Melatonin in energy control: Circadian time-giver and homeostatic monitor. Journal of pineal research. 2024 May; 76(4):e12961. doi: 10.1111/jpi.12961. [PMID: 38751172]
  • Weifeng He, Xueting Wang, Xin Yang, Gaoman Zhang, Junrou Zhang, Li Chen, Piye Niu, Tian Chen. Melatonin mitigates manganese-induced neural damage via modulation of gut microbiota-metabolism in mice. The Science of the total environment. 2024 May; 923(?):171474. doi: 10.1016/j.scitotenv.2024.171474. [PMID: 38447734]
  • Elena Martinez-Cayuelas, Teresa Gavela-Pérez, María Rodrigo-Moreno, Rebeca Losada-Del Pozo, Beatriz Moreno-Vinues, Carmen Garces, Leandro Soriano-Guillén. Sleep Problems, Circadian Rhythms, and Their Relation to Behavioral Difficulties in Children and Adolescents with Autism Spectrum Disorder. Journal of autism and developmental disorders. 2024 May; 54(5):1712-1726. doi: 10.1007/s10803-023-05934-7. [PMID: 36869970]
  • Huanyu Cai, Renjian Li, Yu Chen, Ruiqing Bi, Xueru Fang, Peng Wu, Weilong Xu, Longzhu Bao, Zhu Liu, Jun Li, Guotian Li, Huailong Teng. Rational modification of melatonin for broad-spectrum antifungal agents discovery. Journal of pineal research. 2024 May; 76(4):e12960. doi: 10.1111/jpi.12960. [PMID: 38747028]
  • Jian-Bo Jin, Jing Li, Hong-Bo Wang, Jing-Bo Hu, Chun-Lin Yang. Engineering of VCAM-1-targeted nanostructured lipid carriers for delivery of melatonin against acute lung injury through SIRT1/NLRP3 mediated pyroptosis signaling pathway. International journal of biological macromolecules. 2024 May; 266(Pt 1):130637. doi: 10.1016/j.ijbiomac.2024.130637. [PMID: 38490396]
  • Wenlong Zhang, Yuqi Sun, Hongfeng Wang, Mingfeng Xu, Chunmei He, Congcong Wang, Yongli Yu, Zongshen Zhang, Lingye Su. Exogenous Melatonin Enhances Dihydrochalcone Accumulation in Lithocarpus litseifolius Leaves via Regulating Hormonal Crosstalk and Transcriptional Profiling. International journal of molecular sciences. 2024 Apr; 25(9):. doi: 10.3390/ijms25094592. [PMID: 38731810]
  • Ihsan Muhammad, Shakeel Ahmad, Weijun Shen. Melatonin-Mediated Molecular Responses in Plants: Enhancing Stress Tolerance and Mitigating Environmental Challenges in Cereal Crop Production. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084551. [PMID: 38674136]
  • María Elena Soto, Israel Pérez-Torres, Linaloe Manzano-Pech, Adrían Palacios-Chavarría, Rafael Ricardo Valdez-Vázquez, Verónica Guarner-Lans, Elizabeth Soria-Castro, Eulises Díaz-Díaz, Vicente Castrejón-Tellez. Redox Homeostasis Alteration Is Restored through Melatonin Treatment in COVID-19 Patients: A Preliminary Study. International journal of molecular sciences. 2024 Apr; 25(8):. doi: 10.3390/ijms25084543. [PMID: 38674128]
  • Mohamed Yassine El Brouzi, Mouloud Lamtai, Oussama Zghari, Abdelghafour El Hamzaoui, Ayoub Rezqaoui, Zahra Hadch, Nada Fath, Ali Ouichou, Aboubaker El Hessni, Abdelhalem Mesfioui. Melatonin is a Neuroprotective and Antioxidant Agent against Neurotoxicity Induced by an Intrahippocampal Injection of Nickel in Rats. Neurotoxicity research. 2024 Apr; 42(2):24. doi: 10.1007/s12640-024-00700-8. [PMID: 38598025]
  • Ruina Zhang, Cong Liu, Daolun Yu, Deyong She, Yan Yu, Yongping Cai, Naifu Chen. Melatonin protects oogenesis from hypobaric hypoxia-induced fertility damage in mice. Zygote (Cambridge, England). 2024 Apr; 32(2):161-169. doi: 10.1017/s0967199424000017. [PMID: 38465746]
  • Kun Yang, Jiang-Yan Yong, Yan He, Lu Yu, Gui-Ning Luo, Jilan Chen, Yi-Man Ge, You-Jun Yang, Wei-Jun Ding, Yi-Mei Hu. Melatonin restores DNFB-induced dysbiosis of skin microbiota in a mouse model of atopic dermatitis. Life sciences. 2024 Apr; 342(?):122513. doi: 10.1016/j.lfs.2024.122513. [PMID: 38387700]
  • Osama Alam, Latif Ullah Khan, Adeel Khan, Saleh H Salmen, Mohammad Javed Ansari, Fizza Mehwish, Mushtaq Ahmad, Qamar U Zaman, Hua-Feng Wang. Functional characterisation of Dof gene family and expression analysis under abiotic stresses and melatonin-mediated tolerance in pitaya (Selenicereus undatus). Functional plant biology : FPB. 2024 04; 51(?):. doi: 10.1071/fp23269. [PMID: 38569561]
  • Mona H Soliman, Suliman M S Alghanem, Ibtisam M Alsudays, Abdullah Alaklabi, Basmah M Alharbi, Hadba Al-Amrah, Ehab Azab, Ghalia S H Alnusairi. Co-application of titanium nanoparticles and melatonin effectively lowered chromium toxicity in lemon balm (Melissa officinalis L.) through modifying biochemical characteristics. Environmental science and pollution research international. 2024 Apr; 31(17):25258-25272. doi: 10.1007/s11356-024-32771-7. [PMID: 38468007]
  • Prateek Grover, Ashwani Kumar Singh, Ajeet Kumar, Mrigank Honparkhe, Navdeep Singh, Prahlad Singh. Effect of exogenous melatonin implant on post-thaw semen quality of buffalo bulls. Reproduction in domestic animals = Zuchthygiene. 2024 Apr; 59(4):e14562. doi: 10.1111/rda.14562. [PMID: 38591843]
  • Izabela Kołodziejczyk, Andrzej Kaźmierczak. Melatonin - This is important to know. The Science of the total environment. 2024 Apr; 919(?):170871. doi: 10.1016/j.scitotenv.2024.170871. [PMID: 38340815]
  • Yulei Zhu, Jieying Guo, Fang Wu, Hanqi Yu, Jiahuan Min, Yingtong Zhao, Changhua Tan, Yuanwei Liu, Chuanqiang Xu. Exogenous Melatonin Application Accelerated the Healing Process of Oriental Melon Grafted onto Squash by Promoting Lignin Accumulation. International journal of molecular sciences. 2024 Mar; 25(7):. doi: 10.3390/ijms25073690. [PMID: 38612499]
  • Woong June Park. Have All of the Phytohormonal Properties of Melatonin Been Verified?. International journal of molecular sciences. 2024 Mar; 25(6):. doi: 10.3390/ijms25063550. [PMID: 38542522]
  • Muhammad Aamir Manzoor, Yan Xu, Zhengxin Lv, Jieming Xu, Yuxuan Wang, Wanxia Sun, Xunju Liu, Li Wang, Muhammad Abdullah, Ruie Liu, Songtao Jiu, Caixi Zhang. Comparative genomics of N-acetyl-5-methoxytryptamine members in four Prunus species with insights into bud dormancy and abiotic stress responses in Prunus avium. Plant cell reports. 2024 Mar; 43(4):89. doi: 10.1007/s00299-024-03184-0. [PMID: 38462577]
  • Can Ning, Wenguang Xiao, Zengenni Liang, You Wu, Hui Fan, Siqi Wang, Xiangyi Kong, Yongkang Wang, Aoao Wu, Yuanyuan Li, Zhihang Yuan, Jing Wu, Chenglin Yang. Melatonin alleviates T-2 toxin-induced oxidative damage, inflammatory response, and apoptosis in piglet spleen and thymus. International immunopharmacology. 2024 Mar; 129(?):111653. doi: 10.1016/j.intimp.2024.111653. [PMID: 38354511]
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  • Anna Migni, Francesca Mancuso, Tiziano Baroni, Gabriele Di Sante, Mario Rende, Francesco Galli, Desirée Bartolini. Melatonin as a Repairing Agent in Cadmium- and Free Fatty Acid-Induced Lipotoxicity. Biomolecules. 2023 12; 13(12):. doi: 10.3390/biom13121758. [PMID: 38136629]
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