Prednisolone (BioDeep_00000002685)

 

Secondary id: BioDeep_00000398449

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs


代谢物信息卡片


(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one

化学式: C21H28O5 (360.1937)
中文名称: 泼尼松龙
谱图信息: 最多检出来源 Homo sapiens(plant) 9.88%

Reviewed

Last reviewed on 2024-07-19.

Cite this Page

Prednisolone. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/prednisolone (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000002685). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: C1[C@H]2[C@H]3[C@@H]([C@@]4(C(=CC(=O)C=C4)CC3)C)[C@@H](O)C[C@@]2([C@](C(CO)=O)(O)C1)C
InChI: InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3

描述信息

Prednisolone is only found in individuals that have used or taken this drug. It is a glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. [PubChem]Glucocorticoids such as Prednisolone can inhibit leukocyte infiltration at the site of inflammation, interfere with mediators of inflammatory response, and suppress humoral immune responses. The antiinflammatory actions of glucocorticoids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Prednisolone reduces inflammatory reaction by limiting the capillary dilatation and permeability of the vascular structures. These compounds restrict the accumulation of polymorphonuclear leukocytes and macrophages and reduce the release of vasoactive kinins. Recent research suggests that corticosteroids may inhibit the release of arachidonic acid from phospholipids, thereby reducing the formation of prostaglandins. Prednisolone is a glucocorticoid receptor agonist. On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10371; ORIGINAL_PRECURSOR_SCAN_NO 10370
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10290; ORIGINAL_PRECURSOR_SCAN_NO 10289
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10345; ORIGINAL_PRECURSOR_SCAN_NO 10344
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10328; ORIGINAL_PRECURSOR_SCAN_NO 10327
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10352; ORIGINAL_PRECURSOR_SCAN_NO 10350
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3958; ORIGINAL_PRECURSOR_SCAN_NO 3956
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3963; ORIGINAL_PRECURSOR_SCAN_NO 3958
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3968; ORIGINAL_PRECURSOR_SCAN_NO 3965
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3987; ORIGINAL_PRECURSOR_SCAN_NO 3983
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3980; ORIGINAL_PRECURSOR_SCAN_NO 3979
CONFIDENCE standard compound; INTERNAL_ID 1034; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3991; ORIGINAL_PRECURSOR_SCAN_NO 3989
A - Alimentary tract and metabolism > A07 - Antidiarrheals, intestinal antiinflammatory/antiinfective agents > A07E - Intestinal antiinflammatory agents > A07EA - Corticosteroids acting locally
H - Systemic hormonal preparations, excl. sex hormones and insulins > H02 - Corticosteroids for systemic use > H02A - Corticosteroids for systemic use, plain > H02AB - Glucocorticoids
S - Sensory organs > S01 - Ophthalmologicals > S01C - Antiinflammatory agents and antiinfectives in combination > S01CB - Corticosteroids/antiinfectives/mydriatics in combination
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07X - Corticosteroids, other combinations > D07XA - Corticosteroids, weak, other combinations
A - Alimentary tract and metabolism > A01 - Stomatological preparations > A01A - Stomatological preparations > A01AC - Corticosteroids for local oral treatment
C - Cardiovascular system > C05 - Vasoprotectives > C05A - Agents for treatment of hemorrhoids and anal fissures for topical use > C05AA - Corticosteroids
D - Dermatologicals > D07 - Corticosteroids, dermatological preparations > D07A - Corticosteroids, plain > D07AA - Corticosteroids, weak (group i)
R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AD - Corticosteroids
S - Sensory organs > S03 - Ophthalmological and otological preparations > S03B - Corticosteroids > S03BA - Corticosteroids
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D005938 - Glucocorticoids
S - Sensory organs > S01 - Ophthalmologicals > S01B - Antiinflammatory agents > S01BA - Corticosteroids, plain
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
S - Sensory organs > S02 - Otologicals > S02B - Corticosteroids > S02BA - Corticosteroids
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2783
CONFIDENCE standard compound; INTERNAL_ID 2398
D000893 - Anti-Inflammatory Agents
D000970 - Antineoplastic Agents
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research[1][2].

同义名列表

43 个代谢物同义名

(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one; (11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione; 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene; (11b)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione; (11Β)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione; 11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione; 1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione; 1,4-pregnadiene-3,20-dione-11beta,17alpha,21-triol; 3,20-Dioxo-11β,17α,21-trihydroxy-1,4-pregnadiene; 3,20-Dioxo-11b,17a,21-trihydroxy-1,4-pregnadiene; 11,17,21-Trihydroxypregna-1,4-diene-3,20-dione; 1,4-Pregnadiene-11β,17α,21-triol-3,20-dione; 1,4-Pregnadiene-3,20-dione-11β,17α,21-triol; 1,4-Pregnadiene-11b,17a,21-triol-3,20-dione; 1,4-Pregnadiene-3,20-dione-11b,17a,21-triol; Delta(1)-dehydrohydrocortisone; Prednisolone Sodium Phosphate; Predisolone sodium phosphate; Methylprednisolone acetate; Δ(1)-dehydrohydrocortisone; Delta(1)-dehydrocortisol; Delta(1)-hydrocortisone; Prednisolone tebutate; Prednisolone Acetate; Δ(1)-dehydrocortisol; Δ(1)-hydrocortisone; Deltahydrocortisone; hydroretrocortine; metacortandralone; Prednisolonum; prednisolone; Di adreson F; Delta-Cortef; Prednisolona; Di-adreson-F; Delta(1)-de; DiAdresonF; ST 21:4;O5; Predonine; Δ-cortef; Predate; PRDL; Prednisolone



数据库引用编号

61 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

2 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(2)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ACE, AXIN2, BCL2, PTGS2, VEGFA
Peripheral membrane protein 2 PRTN3, PTGS2
Endoplasmic reticulum membrane 2 BCL2, PTGS2
Nucleus 4 AXIN2, BCL2, MPO, VEGFA
cytosol 3 AXIN2, BCL2, PRTN3
centrosome 1 AXIN2
nucleoplasm 2 MPO, MS4A1
Cell membrane 5 ACE, CD79A, MS4A1, PRTN3, PTPRC
Lipid-anchor 1 MS4A1
Cytoplasmic granule 1 PRTN3
Multi-pass membrane protein 1 MS4A1
Synapse 1 PTPRC
cell surface 4 C3, MS4A1, PTPRC, VEGFA
Golgi apparatus 1 VEGFA
Lysosome 2 ACE, MPO
endosome 1 ACE
plasma membrane 9 ACE, AXIN2, C3, CD79A, CSF2, IL2RA, MS4A1, PRTN3, PTPRC
Membrane 6 ACE, BCL2, IL2RA, MS4A1, PTPRC, VEGFA
caveola 1 PTGS2
extracellular exosome 6 ACE, C3, MPO, MS4A1, PRTN3, PTPRC
endoplasmic reticulum 3 BCL2, PTGS2, VEGFA
extracellular space 14 ACE, C3, CSF2, CSF3, IFNA1, IL2, IL4, IL5, MPO, MS4A1, PRTN3, RNASE3, TG, VEGFA
lysosomal lumen 1 CSF3
adherens junction 1 VEGFA
mitochondrion 1 BCL2
protein-containing complex 3 BCL2, C3, PTGS2
intracellular membrane-bounded organelle 3 CSF2, MPO, PRTN3
Microsome membrane 1 PTGS2
Single-pass type I membrane protein 4 ACE, CD79A, IL2RA, PTPRC
Secreted 11 ACE, C3, CSF2, CSF3, IFNA1, IL2, IL4, IL5, PRTN3, TG, VEGFA
extracellular region 12 ACE, C3, CSF2, CSF3, IL2, IL4, IL5, MPO, PRTN3, RNASE3, TG, VEGFA
cytoplasmic side of plasma membrane 1 PTPRC
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 1 BCL2
mitochondrial outer membrane 1 BCL2
Extracellular side 1 PRTN3
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 1 BCL2
nuclear membrane 1 BCL2
external side of plasma membrane 5 ACE, CD79A, IL2RA, MS4A1, PTPRC
Secreted, extracellular space, extracellular matrix 1 VEGFA
multivesicular body 1 CD79A
beta-catenin destruction complex 1 AXIN2
Membrane raft 3 CD79A, PRTN3, PTPRC
pore complex 1 BCL2
focal adhesion 1 PTPRC
extracellular matrix 1 VEGFA
secretory granule 2 MPO, VEGFA
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
brush border membrane 1 ACE
blood microparticle 1 C3
sperm midpiece 1 ACE
myelin sheath 1 BCL2
basal plasma membrane 1 ACE
azurophil granule 1 MPO
plasma membrane raft 2 MS4A1, PRTN3
secretory granule lumen 1 C3
secretory granule membrane 1 PTPRC
endoplasmic reticulum lumen 2 C3, PTGS2
platelet alpha granule lumen 1 VEGFA
azurophil granule lumen 4 C3, MPO, PRTN3, RNASE3
phagocytic vesicle lumen 1 MPO
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
membrane microdomain 1 PTPRC
bleb 1 PTPRC
endocytic vesicle lumen 1 CSF3
interleukin-2 receptor complex 1 IL2RA
IgM B cell receptor complex 1 CD79A
BAD-BCL-2 complex 1 BCL2
B cell receptor complex 1 CD79A
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA


文献列表

  • Maya Yamato, Tsuyoshi Shirai, Yusho Ishii, Hiroko Sato, Tomonori Ishii, Hiroshi Fujii. Impact of subcutaneous belimumab on disease activity, patient satisfaction, and metabolic profile in long-lasting systemic lupus erythematosus. Clinical rheumatology. 2024 Mar; 43(3):1023-1035. doi: 10.1007/s10067-024-06904-9. [PMID: 38334937]
  • Rana Abutaima, Yousef Al-Ebini, Ahmad Alkofahi, Anas Alshishani, Samar Thiab, Kumarappan C Alagammai, Mohammad Khalid. In vivo assessment of black seed oil single dose on prednisolone pharmacokinetics. The Journal of pharmacy and pharmacology. 2024 Jan; 76(1):57-63. doi: 10.1093/jpp/rgad110. [PMID: 37978932]
  • Ho So, Tsz On Lam, Huan Meng, Steven Ho Man Lam, Lai-Shan Tam. Time and dose-dependent effect of systemic glucocorticoids on major adverse cardiovascular event in patients with rheumatoid arthritis: a population-based study. Annals of the rheumatic diseases. 2023 Nov; 82(11):1387-1393. doi: 10.1136/ard-2023-224185. [PMID: 37487608]
  • M A Perepelova, E L Zaitseva, E G Bessmertnaya, Ya O Grusha, N Yu Sviridenko, G R Galstyan. [An integrated approach to the treatment of pretibial myxedema based on pulse therapy with prednisolone and electrical neuromyostimulation (FREMS-therapy) in a patient with Graves' disease and thyroid eye disease]. Problemy endokrinologii. 2023 08; 69(4):32-37. doi: 10.14341/probl12888. [PMID: 37694865]
  • Nantia Othonos, Riccardo Pofi, Anastasia Arvaniti, Sarah White, Ilaria Bonaventura, Nikolaos Nikolaou, Ahmad Moolla, Thomas Marjot, Roland H Stimson, André P van Beek, Martijn van Faassen, Andrea M Isidori, Elizabeth Bateman, Ross Sadler, Fredrik Karpe, Paul M Stewart, Craig Webster, Joanne Duffy, Richard Eastell, Fatma Gossiel, Thomas Cornfield, Leanne Hodson, K Jane Escott, Andrew Whittaker, Ufuk Kirik, Ruth L Coleman, Charles A B Scott, Joanne E Milton, Olorunsola Agbaje, Rury R Holman, Jeremy W Tomlinson. 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial. Nature communications. 2023 Feb; 14(1):1025. doi: 10.1038/s41467-023-36541-w. [PMID: 36823106]
  • Sen Yang, Shangzhi Wu, Jiaxing Xu, Yuneng Lin, Zhanhang Huang, Xiaowen Chen, Qingyun Xu, Dehui Chen, Chengyu Lu. The effect of therapeutic bronchoalveolar lavage in combination with glucocorticoids on children with acute exogenous lipoid pneumonia. The clinical respiratory journal. 2023 Feb; ?(?):. doi: 10.1111/crj.13575. [PMID: 36807506]
  • Dina E ElMosbah, Marwa S Khattab, Shimaa R Emam, Hala M F El Miniawy. The anti-inflammatory effect of myrrh ethanolic extract in comparison with prednisolone on an autoimmune disease rat model induced by silicate. Inflammopharmacology. 2022 Dec; 30(6):2537-2546. doi: 10.1007/s10787-022-01042-7. [PMID: 35930173]
  • Zahraa R Jabbar, Hayder B Sahib. The Effects of Abscisic Acid on Angiogenesis in Both ex vivo and in vivo Assays. Asian Pacific journal of cancer prevention : APJCP. 2022 Dec; 23(12):4193-4203. doi: 10.31557/apjcp.2022.23.12.4193. [PMID: 36580002]
  • Astrid Solvåg Nesse, Stine Göransson Aanrud, Jan Ludvig Lyche, Trine Sogn, Roland Kallenborn. Confirming the presence of selected antibiotics and steroids in Norwegian biogas digestate. Environmental science and pollution research international. 2022 Dec; 29(57):86595-86605. doi: 10.1007/s11356-022-21479-1. [PMID: 35796924]
  • Gafang Fu, Jia Chen, Hongdeng Qiu. Deep eutectic solvents-derivated carbon dots-decorated silica stationary phase with enhanced separation selectivity in reversed-phase liquid chromatography. Journal of chromatography. A. 2022 Oct; 1681(?):463425. doi: 10.1016/j.chroma.2022.463425. [PMID: 36054993]
  • Prashant D Tailor, Marybeth K Farazdaghi, Sanjay V Patel, Keith H Baratz. Oleander-Associated Keratitis and Uveitis. Cornea. 2022 Oct; 41(10):1305-1307. doi: 10.1097/ico.0000000000003032. [PMID: 36107850]
  • Jelka Kramarič, Rok Ješe, Matija Tomšič, Žiga Rotar, Alojzija Hočevar. COVID-19 among patients with giant cell arteritis: a single-centre observational study from Slovenia. Clinical rheumatology. 2022 Aug; 41(8):2449-2456. doi: 10.1007/s10067-022-06157-4. [PMID: 35366735]
  • Yugo Horiuchi, Kenichi Hashimoto, Hideyuki Horikoshi, Azusa Sano, Yusuke Kawamura, Naoya Fujita, Motohiro Kimata, Yosuke Ono, Yasuhiro Obuchi, Arisa Makino, Mayuko Kaneko, Fumihiko Kimura, Kenji Itoh, Yuji Tanaka. Fulminant elderly adult-onset Still disease effectively treated with tocilizumab and methotrexate: A case report. Medicine. 2022 Jul; 101(28):e29354. doi: 10.1097/md.0000000000029354. [PMID: 35839054]
  • Manabu Miyata, Sotaro Ooto, Yuki Muraoka. Punctate inner choroidopathy immediately after COVID-19 infection: a case report. BMC ophthalmology. 2022 Jul; 22(1):297. doi: 10.1186/s12886-022-02514-8. [PMID: 35799141]
  • Naomi Shimizu, Daiji Ngayama, Yasuhiro Watanabe, Takashi Yamaguchi, Shoko Nakamura, Masahiro Ohira, Atsuhito Saiki, Hiroki Onda, Shuhei Yamaoka, Kazuki Abe, Chiaki Nakaseko, Ichiro Tatsuno. Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma. Journal of chemotherapy (Florence, Italy). 2022 Jul; 34(4):258-263. doi: 10.1080/1120009x.2021.1988202. [PMID: 34661507]
  • Jonathan Aldridge, Anna-Carin Lundell, Kerstin Andersson, Linda Mark, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A Haavardsholm, Michael Nurmohamed, Jon Lampa, Dan Nordström, Kim Hørslev-Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald van Vollenhoven, Anna Rudin. Blood chemokine levels are markers of disease activity but not predictors of remission in early rheumatoid arthritis. Clinical and experimental rheumatology. 2022 Jul; 40(7):1393-1402. doi: 10.55563/clinexprheumatol/idogmj. [PMID: 34796837]
  • Shih-Lung Chen, Chia-Ying Ho, Shy-Chyi Chin. Effects of oral N-acetylcysteine combined with oral prednisolone on idiopathic sudden sensorineural hearing loss. Medicine. 2022 Jul; 101(26):e29792. doi: 10.1097/md.0000000000029792. [PMID: 35777063]
  • Nourin Shakeeb, Prashanth Varkey, Aimy Hynse, Ajit Mandlecha. Anti-inflammatory response of cardamom extract and prediction of therapeutic window in COVID-19 patients by assessing inflammatory markers using RT-PCR. Inflammopharmacology. 2022 Jun; 30(3):883-894. doi: 10.1007/s10787-022-00951-x. [PMID: 35320494]
  • Takuto Shonai, Fumihiko Kimura, Junichi Watanabe. Severe Immune Thrombocytopenia after COVID-19 Vaccination: Two Case Reports and a Literature Review. Internal medicine (Tokyo, Japan). 2022 May; 61(10):1581-1585. doi: 10.2169/internalmedicine.9177-21. [PMID: 35314552]
  • Inae Sim, Jaewoong Jang, Jaewon Song, Jongkyu Lee, Hyemi Lim, Hyun Jung Lee, Gyusik Hwang, Young V Kwon, Doheon Lee, Yoosik Yoon. Paeonia lactiflora extract improves the muscle function of mdx mice, an animal model of Duchenne muscular dystrophy, via downregulating the high mobility group box 1 protein. Journal of ethnopharmacology. 2022 May; 289(?):115079. doi: 10.1016/j.jep.2022.115079. [PMID: 35149132]
  • Indrani Sarkar, Arnab Sen. In silico screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19). Journal of biomolecular structure & dynamics. 2022 05; 40(8):3706-3710. doi: 10.1080/07391102.2020.1850528. [PMID: 33225870]
  • Yoshiyasu Ogura, Sayaka Yabushita, Hideki Aihara, Hiroyuki Tsukada, Toyohiro Hashiba, Satoshi Furuse, Akiko Fujii, Yoshihiko Ueda, Naobumi Mise. A case of proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) that responded favorably to steroid therapy. CEN case reports. 2022 05; 11(2):208-215. doi: 10.1007/s13730-021-00653-3. [PMID: 34628583]
  • Nessreen S Abdelhamid, Maimana A Magdy, Basma H Anwar, Nehal F Farid. US FDA-validated TLC method with four greenness assessment evaluations for simultaneous determination of prednisolone and esomeprazole in spiked human plasma. Biomedical chromatography : BMC. 2022 May; 36(5):e5343. doi: 10.1002/bmc.5343. [PMID: 35062043]
  • Adeel Khan, Kaili Di, Haroon Khan, Nongyue He, Zhiyang Li. Rapid Capturing and Chemiluminescent Sensing of Programmed Death Ligand-1 Expressing Extracellular Vesicles. Biosensors. 2022 Apr; 12(5):. doi: 10.3390/bios12050281. [PMID: 35624582]
  • Suzanne P Stam, Annet Vulto, Michel J Vos, Michiel N Kerstens, Abraham Rutgers, Ido Kema, Daan J Touw, Stephan Jl Bakker, André P van Beek. Rationale and design of the CORE (COrticosteroids REvised) study: protocol. BMJ open. 2022 04; 12(4):e061678. doi: 10.1136/bmjopen-2022-061678. [PMID: 35473729]
  • Shashank Neupane, Prasamsa Pudasaini, Anupam Sharma, Shriya Sharma, Aakriti Adhikari, Kumar Roka. Minimal Change Disease in an Adult: A Case Report. JNMA; journal of the Nepal Medical Association. 2022 Apr; 60(248):399-401. doi: 10.31729/jnma.7433. [PMID: 35633209]
  • Mohammad Zohurul Islam, Martyna Krajewska, Sheikh I Hossain, Krystyna Prochaska, Azraf Anwar, Evelyne Deplazes, Suvash C Saha. Concentration-Dependent Effect of the Steroid Drug Prednisolone on a Lung Surfactant Monolayer. Langmuir : the ACS journal of surfaces and colloids. 2022 04; 38(14):4188-4199. doi: 10.1021/acs.langmuir.1c02817. [PMID: 35344368]
  • Ritesh Agarwal, Valliappan Muthu, Inderpaul Singh Sehgal, Sahajal Dhooria, Kuruswamy Thurai Prasad, Mandeep Garg, Ashutosh Nath Aggarwal, Arunaloke Chakrabarti. A randomised trial of prednisolone versus prednisolone and itraconazole in acute-stage allergic bronchopulmonary aspergillosis complicating asthma. The European respiratory journal. 2022 04; 59(4):. doi: 10.1183/13993003.01787-2021. [PMID: 34503983]
  • Susan Ruyu Qi, Mélanie Hébert, Eunice You, Jean-Philippe Proulx-Gauthier, Marie Eve Légaré. Conjunctival Infiltration in a Child as a Rare Manifestation of IgG4-Related Disease. Cornea. 2022 Apr; 41(4):496-498. doi: 10.1097/ico.0000000000002773. [PMID: 34050069]
  • Chinmay Chetan, Suprabha Patnaik, Pradeep Suryawanshi, Reema Garegrat. Sirolimus used for treatment of retroperitoneal arteriovenous malformation in a premature neonate. BMJ case reports. 2022 Mar; 15(3):. doi: 10.1136/bcr-2021-246265. [PMID: 35260399]
  • Priyanka Pagh, Ann-Kathrine Rossau. [COVID-19 induced Stevens-Johnson syndrome]. Ugeskrift for laeger. 2022 03; 184(10):. doi: NULL. [PMID: 35315755]
  • Ece Altun, Elif Kuzucular. Leukocytoclastic vasculitis after COVID-19 vaccination. Dermatologic therapy. 2022 Mar; 35(3):e15279. doi: 10.1111/dth.15279. [PMID: 34931412]
  • Daisuke Hidaka, Reiki Ogasawara, Shunsuke Sugimura, Fumiaki Fujii, Keisuke Kojima, Jun Nagai, Ko Ebata, Kohei Okada, Naoki Kobayashi, Masahiro Ogasawara, Masahiro Imamura, Shuichi Ota. New-onset Evans syndrome associated with systemic lupus erythematosus after BNT162b2 mRNA COVID-19 vaccination. International journal of hematology. 2022 Mar; 115(3):424-427. doi: 10.1007/s12185-021-03243-2. [PMID: 34687421]
  • Qingquan Chen, Qiongxiu Yang, Yingying Fang, Gongping Chen, Xiaoting Lv. Potential benefits of precise corticosteroid therapy for critical COVID-19. Respiratory physiology & neurobiology. 2022 03; 297(?):103813. doi: 10.1016/j.resp.2021.103813. [PMID: 34801741]
  • Vartika, Monika Chaudhary, Sameer Suresh Bhagyawant, Nidhi Srivastava. Effects of Prednisolone Derivative and Panaxydol: Biosurfactants on Cell Wall Integrity of Acne-Causing Resistant Bacteria. Cell biochemistry and biophysics. 2022 Mar; 80(1):229-243. doi: 10.1007/s12013-021-01038-0. [PMID: 34709575]
  • Eri Sugawara, Taiki Sato, Yoshiharu Amasaki, Kazuaki Katsumata. Successful treatment with tocilizumab for refractory anemia and slowly progressive renal glomerulosclerosis in multicentric Castleman disease: A case report. Medicine. 2022 Feb; 101(8):e28941. doi: 10.1097/md.0000000000028941. [PMID: 35212301]
  • Keitaro Ogaki, Hiroaki Fujita, Norito Kokubun, Mai Hamaguchi, Ichizo Nishino, Keisuke Suzuki. [Anti-mitochondrial M2 antibody-positive myositis preceded by heart failure and cardiac conduction disturbance. A case report]. Rinsho shinkeigaku = Clinical neurology. 2022 Feb; 62(2):135-139. doi: 10.5692/clinicalneurol.cn-001644. [PMID: 35095048]
  • M I Mantelli, B B Roques, T A Blanchard, M Mounier, M Quincey, F B Jolivet, N P Jousserand, A Marchand, A N Diquélou, B S Reynolds, M Coyne, C Trumel, H P Lefebvre, D Concordet, R Lavoué. Short course of immune-suppressive doses of prednisolone, evaluated through a prospective double-masked placebo-controlled clinical trial in healthy Beagles, is associated with sustained modifications in renal, hydration, and electrolytic status. American journal of veterinary research. 2022 Feb; 83(5):434-442. doi: 10.2460/ajvr.21.09.0150. [PMID: 35175932]
  • Shun Aoki, Satoshi Deyama, Rinako Sugie, Kohei Ishimura, Hayato Fukuda, Satoshi Shuto, Masabumi Minami, Katsuyuki Kaneda. The antidepressant-like effect of resolvin E1 in repeated prednisolone-induced depression model mice. Behavioural brain research. 2022 02; 418(?):113676. doi: 10.1016/j.bbr.2021.113676. [PMID: 34801580]
  • Nehal F Farid, Maimana A Magdy, Basma H Anwar, Nessreen S Abdelhamid. Multivariate Model Update Chemometric Methods for Determination of Prednisolone and Esomeprazole in Spiked Human Plasma: A Comparative Study. Journal of AOAC International. 2022 Feb; 105(1):317-322. doi: 10.1093/jaoacint/qsab114. [PMID: 34478551]
  • Paul Torpiano, Stephen Holwill, David Pace. Mesangiocapillary glomerulonephritis complicating pulmonary tuberculosis. CEN case reports. 2022 02; 11(1):17-21. doi: 10.1007/s13730-021-00626-6. [PMID: 34260011]
  • Midori Awazu, Mamiko Yamada, Nariaki Asada, Akinori Hashiguchi, Kenjiro Kosaki, Kazuya Matsumura. A girl with a mutation of the ciliary gene CC2D2A presenting with FSGS and nephronophthisis. CEN case reports. 2022 02; 11(1):116-119. doi: 10.1007/s13730-021-00640-8. [PMID: 34435324]
  • Sahajal Dhooria, Shivani Chaudhary, Inderpaul Singh Sehgal, Ritesh Agarwal, Siddhant Arora, Mandeep Garg, Nidhi Prabhakar, Goverdhan Dutt Puri, Ashish Bhalla, Vikas Suri, Lakshmi Narayana Yaddanapudi, Valliappan Muthu, Kuruswamy Thurai Prasad, Ashutosh Nath Aggarwal. High-dose versus low-dose prednisolone in symptomatic patients with post-COVID-19 diffuse parenchymal lung abnormalities: an open-label, randomised trial (the COLDSTER trial). The European respiratory journal. 2022 02; 59(2):. doi: 10.1183/13993003.02930-2021. [PMID: 34887325]
  • Shereen Farghaly, Mohammed Badedi, Rehab Ibrahim, Murad H Sadhan, Aymn Alamoudi, Awaji Alnami, Abdulrahman Muhajir. Clinical characteristics and outcomes of post-COVID-19 pulmonary fibrosis: A case-control study. Medicine. 2022 Jan; 101(3):e28639. doi: 10.1097/md.0000000000028639. [PMID: 35060549]
  • Margaret M Ewald, Amy J Rankin, Jessica M Meekins, Geraldine Magnin, Butch KuKanich. Prednisolone and dexamethasone are systemically absorbed after topical application of ophthalmic suspensions in healthy dogs. American journal of veterinary research. 2022 Jan; 83(4):339-348. doi: 10.2460/ajvr.21.04.0059. [PMID: 35038305]
  • Yuka Okura, Yasuyoshi Hiramatsu, Masaki Shimomura, Kota Taniguchi, Mitsuru Nawate, Yutaka Takahashi, Ichiro Kobayashi. Successful treatment of IgA vasculitis with prolonged cutaneous manifestation with colchicine in a 10-year-old boy. Modern rheumatology case reports. 2022 Jan; 6(1):97-100. doi: 10.1093/mrcr/rxab041. [PMID: 34730811]
  • Tatsuya Kawasaki, Seido Ooka, Machiko Mizushima, Yuta Nakamura, Hiroki Ikeda, Tsutomu Sakurada, Shotaro Suzuki, Kazuko Yamazaki, Yutaka Goto, Keiichi Sakurai, Yamasaki Yukitaka, Tomofumi Kiyokawa, Kumiko Tonooka, Hiroyuki Kunishima, Kimito Kawahata. COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes. Modern rheumatology case reports. 2022 01; 6(1):101-105. doi: 10.1093/mrcr/rxab032. [PMID: 34592766]
  • Hanui Park, Miji Lee, Jin Seon Jeong. A case of vasculitis triggered by infective endocarditis in a patient undergoing maintenance hemodialysis: a case report. BMC nephrology. 2022 01; 23(1):13. doi: 10.1186/s12882-021-02647-w. [PMID: 34979975]
  • Dale Ventour, Rheana Sieunarine, Chavin Gopaul. A Short Course of Prednisolone in Patients With Moderate Covid 19 Respiratory Failure- Stop the Progression a Case Series. Journal of investigative medicine high impact case reports. 2022 Jan; 10(?):23247096221090843. doi: 10.1177/23247096221090843. [PMID: 35426322]
  • Geetika Chhabra, Prashant Verma, Anju Nagar. Bilateral Vitreous Hemorrhage in a Young Man with Pustular Psoriasis. Skinmed. 2022; 20(1):69-71. doi: . [PMID: 35435829]
  • Kai-Che Wei, Shih-Fan Lai, Wei-Lun Huang, Kuo-Chung Yang, Ping-Chin Lai, Wan-Ju Wei, Tsung-Hsien Chang, Yun-Chen Huang, Ya-Chuan Tsai, Shin-Chih Lin, Sun-Jang Lin, Shih-Chieh Lin. An innovative targeted therapy for fluoroscopy-induced chronic radiation dermatitis. Journal of molecular medicine (Berlin, Germany). 2022 01; 100(1):135-146. doi: 10.1007/s00109-021-02146-3. [PMID: 34689211]
  • Hasan Calis, Zulfikar Karabulut, Yilmaz Guler, Serkan Sengul. Idiopathic granulomatous mastitis and steroid use during the pandemic of COVID-19. Breast disease. 2022; 41(1):145-149. doi: 10.3233/bd-210054. [PMID: 35068437]
  • Martin T Christian, Nicholas Ja Webb, Rebecca L Woolley, Nafsika Afentou, Samir Mehta, Emma Frew, Elizabeth A Brettell, Adam R Khan, David V Milford, Detlef Bockenhauer, Moin A Saleem, Angela S Hall, Ania Koziell, Heather Maxwell, Shivaram Hegde, Eric R Finlay, Rodney D Gilbert, Caroline Jones, Karl McKeever, Wendy Cook, Natalie Ives. Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection: PREDNOS2 RCT. Health technology assessment (Winchester, England). 2022 01; 26(3):1-94. doi: 10.3310/wtfc5658. [PMID: 35060851]
  • Taotao Zhou, Florian Fronhoffs, Leona Dold, Christian P Strassburg, Tobias J Weismüller. New-onset autoimmune hepatitis following mRNA COVID-19 vaccination in a 36-year-old woman with primary sclerosing cholangitis - should we be more vigilant?. Journal of hepatology. 2022 01; 76(1):218-220. doi: 10.1016/j.jhep.2021.08.006. [PMID: 34450237]
  • Yasuaki Hirooka, Saki Okuda, Masafumi Sugiyama, Toshihiko Shiga, Yuji Nozaki, Koji Kinoshita, Masanori Funauchi, Itaru Matsumura. Case Report: A Rare Case of Elderly-Onset Adult-Onset Still's Disease in a Patient With Systemic Lupus Erythematosus. Frontiers in immunology. 2022; 13(?):822169. doi: 10.3389/fimmu.2022.822169. [PMID: 35116046]
  • W Douglas Biggar, Andrew Skalsky, Craig M McDonald. Comparing Deflazacort and Prednisone in Duchenne Muscular Dystrophy. Journal of neuromuscular diseases. 2022; 9(4):463-476. doi: 10.3233/jnd-210776. [PMID: 35723111]
  • Yuya Kishida, Naoki Shingai, Shinji Nakao, Shinya Ishida, Keita Yamamoto, Shuhei Kurosawa, Yutaro Hino, Keiichiro Hattori, Yasushi Senoo, Kosuke Yoshioka, Takashi Toya, Yuho Najima, Takeshi Kobayashi, Hisashi Sakamaki, Kazuteru Ohashi, Noriko Doki. [Late-onset refractory autoimmune hemolytic anemia following autologous hematologic recovery after allo-HSCT in aplastic anemia-PNH syndrome]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2022; 63(5):347-352. doi: 10.11406/rinketsu.63.347. [PMID: 35662156]
  • Haruki Matsumoto, Yuya Fujita, Masahiko Fukatsu, Takayuki Ikezoe, Kohei Yokose, Tomoyuki Asano, Naomi Tsuchida, Ayaka Maeda, Shuhei Yoshida, Honami Hashimoto, Jumpei Temmoku, Naoki Matsuoka, Makiko Yashiro-Furuya, Shuzo Sato, Mai Murakami, Hidenori Sato, Chiharu Sakuma, Kazumasa Kawashima, Norshalena Shakespear, Yuri Uchiyama, Hiroshi Watanabe, Yohei Kirino, Naomichi Matsumoto, Kiyoshi Migita. Case Report: Coexistence of Multiple Myeloma and Auricular Chondritis in VEXAS Syndrome. Frontiers in immunology. 2022; 13(?):897722. doi: 10.3389/fimmu.2022.897722. [PMID: 35757758]
  • Katsuyuki Tanabe, Natsumi Matsuoka-Uchiyama, Tomoyo Mifune, Chieko Kawakita, Hitoshi Sugiyama, Jun Wada. Management of corticosteroid-dependent eosinophilic interstitial nephritis: A case report. Medicine. 2021 Dec; 100(50):e28252. doi: 10.1097/md.0000000000028252. [PMID: 34918693]
  • Isabel Garrido, Susana Lopes, Manuel Sobrinho Simões, Rodrigo Liberal, Joanne Lopes, Fátima Carneiro, Guilherme Macedo. Autoimmune hepatitis after COVID-19 vaccine - more than a coincidence. Journal of autoimmunity. 2021 12; 125(?):102741. doi: 10.1016/j.jaut.2021.102741. [PMID: 34717185]
  • Dan Chang, Minmin Gong, Chaofan Liu, Quan Zhang, Ziwei Hu, Zhuoguang Li. Efficacy and safety of rituximab for childhood refractory nephrotic syndrome: A meta-analysis of randomized controlled trials. Medicina clinica. 2021 Nov; 157(9):418-426. doi: 10.1016/j.medcli.2020.07.039. [PMID: 33070945]
  • Hormat Rahimzadeh, Mohammad Keykhaei, Effat Razeghi, Ensieh Zivari, Ensieh Sadat Mansouri. COVID-19 progression in kidney transplant recipients: a single-center case series. CEN case reports. 2021 11; 10(4):494-499. doi: 10.1007/s13730-021-00584-z. [PMID: 33770414]
  • Yasuo Suehiro, Hiroyuki Seo, Shigefumi Suehiro, Hidekazu Hirai. Surgical strategy of IgG4-related inflammatory abdominal aortic aneurysm with preoperative steroid therapy: A case report. Annals of vascular surgery. 2021 Nov; 77(?):351.e1-351.e6. doi: 10.1016/j.avsg.2021.05.041. [PMID: 34437961]
  • Ronald P Hall, Gregory L Mutumi, Brandon P Hedrick, Laurel R Yohe, Alexa Sadier, Kalina T J Davies, Stephen J Rossiter, Karen Sears, Liliana M Dávalos, Elizabeth R Dumont. Find the food first: An omnivorous sensory morphotype predates biomechanical specialization for plant based diets in phyllostomid bats. Evolution; international journal of organic evolution. 2021 11; 75(11):2791-2801. doi: 10.1111/evo.14270. [PMID: 34021589]
  • Yohei Okuda, Sohei Kuribayashi, Takuya Okusa, Go Tanigawa, Yasuhiro Matsuoka, Shigeki Fujita, Yasushi Miyagawa. [A Case of IgG4-Related Disease Arising in Female Periurethra]. Hinyokika kiyo. Acta urologica Japonica. 2021 Nov; 67(11):507-510. doi: 10.14989/actauroljap_67_11_507. [PMID: 34856791]
  • Michael Stucki, Clarissa D Voegel, Tina M Binz, Thomas Kraemer, Arnold Lavaud, Katrin Voelter. Systemic detectability of dexamethasone and prednisolone after eye drop application in horses. Equine veterinary journal. 2021 Nov; 53(6):1250-1256. doi: 10.1111/evj.13418. [PMID: 33421187]
  • Koen Deventer, Michael Polet, Wim Van Gansbeke, Fiona Hooghe, Helen Van Hoecke, Peter Van Eenoo. Investigation of the urinary excretion of prednisolone and metabolites after nasal administration: Relevance to doping control. Drug testing and analysis. 2021 Nov; 13(11-12):1897-1905. doi: 10.1002/dta.3105. [PMID: 34081842]
  • Most Nazma Parvin, Md Abdul Aziz, Sikder Nahidul Islam Rabbi, Mir Md Abdullah Al-Mamun, Mohammed Hanif, Md Saiful Islam, Mohammad Safiqul Islam. Assessment of the Link of ABCB1 and NR3C1 gene polymorphisms with the prednisolone resistance in pediatric nephrotic syndrome patients of Bangladesh: A genotype and haplotype approach. Journal of advanced research. 2021 11; 33(?):141-151. doi: 10.1016/j.jare.2021.02.001. [PMID: 34603785]
  • Rahul Sinha, Arvinder Wander, Anirudh Kapoor, Richa Yadav, Atin Kumar, Sheffali Gulati. Acute Demyelinating Syndrome (MOG Antibody Positive) Associated With COVID-19 Infection: A Widening spectrum. Clinical pediatrics. 2021 11; 60(13):501-503. doi: 10.1177/00099228211037210. [PMID: 34344226]
  • Eric Y Kok, Lakshmi Srivaths, Amanda B Grimes, Tiphanie P Vogel, S Kristen Sexson Tejtel, Eyal Muscal. Immune thrombocytopenia following multisystem inflammatory syndrome in children (MIS-C) - a case series. Pediatric hematology and oncology. 2021 Oct; 38(7):663-668. doi: 10.1080/08880018.2021.1917737. [PMID: 33949910]
  • Oktay Perk, Tanıl Kendirli, Handan Dinçaslan, Ebru Azapağası, Gokcen Meral. Overlap Stevens Johnson Syndrome/Toxic Epidermal Necrolysis developed due to the use of toxic-dose vinblastine in case of Langerhans Cell Histiocytosis(Letterer-Siwe). Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2021 Oct; 60(5):103173. doi: 10.1016/j.transci.2021.103173. [PMID: 34215518]
  • Pratap Kumar Patra, Sanjib Kumar Mondal, Manphool Singhal, Rajni Kumrah, Ankur Kumar Jindal, Michael Hershfield, Surjit Singh. Deficiency of Adenosine Deaminase 2-a Monogenic Cause of Wunderlich Syndrome. Journal of clinical immunology. 2021 10; 41(7):1693-1695. doi: 10.1007/s10875-021-01097-1. [PMID: 34259954]
  • Tommaso D'Angelo, Antonino Cattafi, Maria Ludovica Carerj, Christian Booz, Giorgio Ascenti, Giuseppe Cicero, Alfredo Blandino, Silvio Mazziotti. Myocarditis After SARS-CoV-2 Vaccination: A Vaccine-Induced Reaction?. The Canadian journal of cardiology. 2021 10; 37(10):1665-1667. doi: 10.1016/j.cjca.2021.05.010. [PMID: 34118375]
  • Mostafa Ghanei, Masoud Solaymani-Dodaran, Ali Qazvini, Amir Hosein Ghazale, Seyed Amin Setarehdan, Seyed Hassan Saadat, Hassan Ghobadi, Saeed Hoseininia, Maryam Elahikhah, Ali Hossein Samadi, Yousef Imani, Ensieh Vahedi, Farhang Babamahmoodi, Fatemeh Tajik Rostami, Mohammad Hossein Azimzadeh Ardebili, Akram Ansarifar, Fatemeh Fallahpoor Golmaei, Atieh Asadollah. The efficacy of corticosteroids therapy in patients with moderate to severe SARS-CoV-2 infection: a multicenter, randomized, open-label trial. Respiratory research. 2021 Sep; 22(1):245. doi: 10.1186/s12931-021-01833-6. [PMID: 34526033]
  • James Richardson-May, Alice Rothwell, Mohammed Rashid. Reactivation of herpes simplex keratitis following vaccination for COVID-19. BMJ case reports. 2021 Sep; 14(9):. doi: 10.1136/bcr-2021-245792. [PMID: 34493563]
  • Szu-Ting Yang, Chang-Chin Yeh, Wen-Ling Lee, Fa-Kung Lee, Cheng-Chang Chang, Peng-Hui Wang. A symptomatic near-term pregnant woman recovered from SARS-CoV-2 infection. Taiwanese journal of obstetrics & gynecology. 2021 Sep; 60(5):945-948. doi: 10.1016/j.tjog.2021.07.046. [PMID: 34507682]
  • Pamela Galati, Todd Archer, Robyn Jolly, Alyssa Sullivant, Robert Wills, Patty Lathan. Effects of desmopressin acetate administration in healthy dogs receiving prednisolone. Journal of veterinary internal medicine. 2021 Sep; 35(5):2271-2276. doi: 10.1111/jvim.16250. [PMID: 34448503]
  • Georges El Hasbani, Ali T Taher, Ali S M Jawad, Imad Uthman. Henoch-Schönlein purpura: Another COVID-19 complication. Pediatric dermatology. 2021 Sep; 38(5):1359-1360. doi: 10.1111/pde.14699. [PMID: 34272762]
  • Sohaib Ashraf, Muhammad Ahmad Imran, Shoaib Ashraf, Hadiqa-Tul Hafsa, Saffa Khalid, Muhammad Kiwan Akram, Muhammad Ghufran, Kamran Khalid Cheema, Ali Ahmad, Mateen Izhar. COVID-19: A Potential Trigger for Thyroid Dysfunction. The American journal of the medical sciences. 2021 09; 362(3):303-307. doi: 10.1016/j.amjms.2021.05.013. [PMID: 34023311]
  • Élise Vuille-Lessard, Matteo Montani, Jaume Bosch, Nasser Semmo. Autoimmune hepatitis triggered by SARS-CoV-2 vaccination. Journal of autoimmunity. 2021 09; 123(?):102710. doi: 10.1016/j.jaut.2021.102710. [PMID: 34332438]
  • Tetsuro Tamai, Kaori Kamijo, Yoshifusa Abe, Satoshi Hibino, Shunsuke Sakurai, Shuichiro Watanabe, Yoshitaka Watanabe, Satomi Nimura, Atsutoshi Shiratori, Takaaki Takayanagi, Tsuneki Watanabe, Yuya Nakano, Hirokazu Ikeda, Kazushige Dobashi, Yasuko Nakano, Katsumi Mizuno, Kazuo Itabashi. Distribution of serum adiponectin isoforms in pediatric patients with steroid-sensitive nephrotic syndrome. Clinical and experimental nephrology. 2021 Sep; 25(9):1027-1034. doi: 10.1007/s10157-021-02085-w. [PMID: 34061287]
  • Sepehr Feizi, Aidin Meshksar, Ali Naderi, Hamed Esfandiari. Anterior Scleritis Manifesting After Coronavirus Disease 2019: A Report of Two Cases. Cornea. 2021 Sep; 40(9):1204-1206. doi: 10.1097/ico.0000000000002795. [PMID: 34351874]
  • Anne M Schijvens, Nynke Teeninga, Eiske M Dorresteijn, Steven Teerenstra, Nicholas J Webb, Michiel F Schreuder. Steroid treatment for the first episode of childhood nephrotic syndrome: comparison of the 8 and 12 weeks regimen using an individual patient data meta-analysis. European journal of pediatrics. 2021 Sep; 180(9):2849-2859. doi: 10.1007/s00431-021-04035-w. [PMID: 33774744]
  • Narges Karimi, Ali Asghar Okhovat, Bentolhoda Ziaadini, Bahram Haghi Ashtiani, Shahriar Nafissi, Farzad Fatehi. Myasthenia gravis associated with novel coronavirus 2019 infection: A report of three cases. Clinical neurology and neurosurgery. 2021 Sep; 208(?):106834. doi: 10.1016/j.clineuro.2021.106834. [PMID: 34329810]
  • Shailendra Shrestha, Rahul Yadav. Remission after Six Months of Induction Immunosuppressive Treatment with Mycofenolate Mofetil and Prednisolone in Patients with Lupus Nephritis: A Descriptive Cross-sectional Study. JNMA; journal of the Nepal Medical Association. 2021 Aug; 59(240):791-794. doi: 10.31729/jnma.6826. [PMID: 34508471]
  • Boxuan Ma, Hong Xu, Yanan Wang, Li Yang, Weihua Zhuang, Gaocan Li, Yunbing Wang. Biomimetic-Coated Nanoplatform with Lipid-Specific Imaging and ROS Responsiveness for Atherosclerosis-Targeted Theranostics. ACS applied materials & interfaces. 2021 Aug; 13(30):35410-35421. doi: 10.1021/acsami.1c08552. [PMID: 34286950]
  • Risa Ohsawa, Hozumi Sano, Mitsunori Ikeda, Shigetoshi Sano. Clinical and histopathological views of morbilliform rash after COVID-19 mRNA vaccination mimic those in SARS-CoV-2 virus infection-associated cutaneous manifestations. Journal of dermatological science. 2021 Aug; 103(2):124-127. doi: 10.1016/j.jdermsci.2021.06.006. [PMID: 34167874]
  • M Lam, M Egail, A J Bedlow, S Tso. Ribonucleic acid COVID-19 vaccine-associated cutaneous adverse drug events: a case series of two patients. Clinical and experimental dermatology. 2021 08; 46(6):1131-1134. doi: 10.1111/ced.14673. [PMID: 33835617]
  • Petra Richter, Hendryk Fischer, René Dörfelt. Immunoadsorption in a dog with severe immune mediated hemolytic anemia. Journal of clinical apheresis. 2021 Aug; 36(4):668-672. doi: 10.1002/jca.21913. [PMID: 34033686]
  • Melca Maria Oliveira Barros, Fauze Lutfe Ayoub, Giovanna Lemos, Kelly Cristina Brasileiro, Priscilla Brito da Silva Icibaci, Elyse Moritz, Juliana Oliveira Martins, Carolina Bonet Bub, Akemi Kuroda Chiba, Jose Orlando Bordin. Autoimmune pancytopenia after liver transplantation: A case report. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2021 Aug; 60(4):103136. doi: 10.1016/j.transci.2021.103136. [PMID: 33895070]
  • Christopher Martin Allen, Shelby Ramsamy, Alexander William Tarr, Patrick Jason Tighe, William Lucien Irving, Radu Tanasescu, Jonathan Rhys Evans. Guillain-Barré Syndrome Variant Occurring after SARS-CoV-2 Vaccination. Annals of neurology. 2021 08; 90(2):315-318. doi: 10.1002/ana.26144. [PMID: 34114269]
  • Yin Long, Shangzhu Zhang, Jiuliang Zhao, Hanxiao You, Li Zhang, Jing Li, Xiaomei Leng, Qian Wang, Xinping Tian, Mengtao Li, Xiaofeng Zeng. Risk of osteonecrosis in systemic lupus erythematosus: An 11-year Chinese single-center cohort study. Lupus. 2021 Aug; 30(9):1459-1468. doi: 10.1177/09612033211021166. [PMID: 34082592]
  • Alicia Pareja-Ríos, Sergio Bonaque-González. Late Corneal Stromal Deposits After COVID-19. Cornea. 2021 08; 40(8):1067-1069. doi: 10.1097/ico.0000000000002757. [PMID: 34029243]
  • Tilde Kristensen, Henrik Birn, Per Ivarsen. A randomised controlled unblinded multicentre non-inferiority trial with activated vitamin D and prednisolone treatment in patients with minimal change nephropathy (ADAPTinMCN). Trials. 2021 Jul; 22(1):442. doi: 10.1186/s13063-021-05393-4. [PMID: 34247632]
  • Sebastiaan D T Sassen, Ron A A Mathôt, Rob Pieters, Valérie de Haas, Gertjan J L Kaspers, Cor van den Bos, Wim J E Tissing, D Maroeska W W Te Loo, Marc B Bierings, Inge M van der Sluis, C Michel Zwaan. Evaluation of the pharmacokinetics of prednisolone in paediatric patients with acute lymphoblastic leukaemia treated according to Dutch Childhood Oncology Group protocols and its relation to treatment response. British journal of haematology. 2021 07; 194(2):423-432. doi: 10.1111/bjh.17572. [PMID: 34060065]
  • Kazuki Mitsuru Matsuda, Ayumi Yoshizaki, Hirohito Kotani, Ai Kuzumi, Maiko Fukayama, Satoshi Ebata, Takemichi Fukasawa, Asako Yoshizaki-Ogawa, Shinichi Sato. Development of a prediction model of treatment response in patients with cutaneous arteritis: Insights from a cohort of 33 patients. The Journal of dermatology. 2021 Jul; 48(7):1021-1026. doi: 10.1111/1346-8138.15868. [PMID: 33768589]
  • Mai Kawazoe, Kaichi Kaneko, Toshihiro Nanki. Glucocorticoid therapy suppresses Wnt signaling by reducing the ratio of serum Wnt3a to Wnt inhibitors, sFRP-1 and Wif-1. Clinical rheumatology. 2021 Jul; 40(7):2947-2954. doi: 10.1007/s10067-020-05554-x. [PMID: 33420868]
  • K P Jayawickreme, S Subasinghe, S Weerasinghe, L Perera, P Dissanayaka. A young girl with chronic isolated cervical lymphadenopathy found to have lupus lymphadenopathy, progressing to develop lupus nephritis: a case report. Journal of medical case reports. 2021 Jun; 15(1):328. doi: 10.1186/s13256-021-02949-5. [PMID: 34176492]
  • Ondrej Suchanek, David R W Jayne, Rachel B Jones. Therapeutic dilemmas in relapsing renal ANCA-associated vasculitis. Rheumatology (Oxford, England). 2021 06; 60(Suppl 3):iii60-iii62. doi: 10.1093/rheumatology/keab178. [PMID: 34137872]