Docosahexaenoic acid (BioDeep_00000002670)

 

Secondary id: BioDeep_00000178497, BioDeep_00000229598, BioDeep_00000265243, BioDeep_00001868094

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 natural product


代谢物信息卡片


(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid

化学式: C22H32O2 (328.2402)
中文名称: 顺式-4,7,10,13,16,19-二十二碳六烯酸(DHA), 4Z,7Z,10Z,13Z,16Z,19Z-二十二碳六烯酸, 顺式-4,7,10,13,16,19-二十二碳六烯酸, 二十二碳六烯酸
谱图信息: 最多检出来源 Homo sapiens(feces) 12.49%

分子结构信息

SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O
InChI: InChI=1S/C22H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-

描述信息

Docosahexaenoic acid (DHA) is an omega-3 essential fatty acid. Chemically, DHA is a carboxylic acid with a 22-carbon chain and six cis- double bonds with the first double bond located at the third carbon from the omega end. DHA is most often found in fish oil. It is a major fatty acid in sperm and brain phospholipids, especially in the retina. Dietary DHA can reduce the level of blood triglycerides in humans, which may reduce the risk of heart disease (Wikipedia). Docosahexaenoic acid is found to be associated with isovaleric acidemia, which is an inborn error of metabolism.
Extensively marketed as a dietary supplement in Japan [DFC]. Doconexent is found in many foods, some of which are mung bean, fruit preserve, northern pike, and snapper.
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk.

同义名列表

49 个代谢物同义名

(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,1 6,19-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-Docosahexaenoic acid; 4-cis,7-cis,10-cis,13-cis,16-cis,19-cis-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoate; Docosahexaenoic acid, 4,7,10,13,16,19-(all-Z-isomer); Docosahexaenoic acid, 4,7,10,13,16,19-isomer; all-cis-4,7,10,13,16,19-Docosahexaenoic acid; (all-Z)-4,7,10,13,16,19-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexenoic acid; 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid; delta4,7,10,13,16,19-Docosahexaenoic acid; (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoate; all-cis-4,7,10,13,16,19-Docosahexaenoate; cis-4,7,10,13,16,19-Docosahexanoic acid; 4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoate; DOCOSA-4,7,10,13,16,19-hexaenoIC ACID; Δ4,7,10,13,16,19-docosahexaenoic acid; 4,7,10,13,16,19-Docosahexaenoic acid; Docosahexaenoic acid (all-Z isomer); cis-4,7,10,13,16,19-Docosahexanoate; DOCOSA-4,7,10,13,16,19-hexaenoate; 4,7,10,13,16,19-Docosahexaenoate; FA(22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Choline docosahexaenoic acid; all-Z-Docosahexaenoic acid; Choline docosahexaenoate; all-Z-Docosahexaenoate; Docosahexaenoylcholine; Acids, docosahexaenoic; 22:6-4, 7,10,13,16,19; Acids, docosahexenoic; DOCOSAHEXAENOIC ACID; DHA;Cervonic Acid; Docosahexaenoate; Cervonic acid; Doconexentum; all-cis-DHA; Doconexento; FA(22:6n3); Doconexent; Doxonexent; 22:6(N-3); Cervonate; Efalex; DHA; Doconexent; 4Z,7Z,10Z,13Z,16Z,19Z-Docosahexaenoic Acid (DHA)



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

32 个相关的代谢反应过程信息。

Reactome(30)

BioCyc(0)

WikiPathways(2)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

24 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 9 ADIG, ALB, APOB, APOE, BDNF, PPARG, PTGS1, PTGS2, SREBF1
Peripheral membrane protein 3 CYP1B1, PTGS1, PTGS2
Endosome membrane 1 APOB
Endoplasmic reticulum membrane 8 APOB, CYP1B1, ELOVL5, FADS1, HSP90B1, PTGS1, PTGS2, SREBF1
Nucleus 6 ADIG, ALB, APOE, HSP90B1, PPARG, SREBF1
cytosol 6 ALB, APOB, HSP90B1, NGF, PPARG, SREBF1
dendrite 4 APOE, BDNF, ELOVL5, NGF
centrosome 1 ALB
nucleoplasm 2 PPARG, SREBF1
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 2 FFAR1, GPRC5A
Multi-pass membrane protein 5 ELOVL5, FADS1, FFAR1, GPRC5A, SREBF1
Golgi apparatus membrane 1 SREBF1
cell surface 1 ADIPOQ
glutamatergic synapse 1 APOE
Golgi apparatus 3 ALB, APOE, PTGS1
Golgi membrane 2 INS, SREBF1
neuronal cell body 3 APOB, APOE, ELOVL5
smooth endoplasmic reticulum 2 APOB, HSP90B1
synaptic vesicle 2 BDNF, NGF
plasma membrane 5 APOB, APOE, F2, FFAR1, GPRC5A
Membrane 7 ADIG, APOE, BDNF, CYP1B1, ELOVL5, FADS1, HSP90B1
axon 2 BDNF, NGF
caveola 1 PTGS2
extracellular exosome 7 ALB, APOB, APOE, F2, GPRC5A, HSP90B1, PTGS1
endoplasmic reticulum 7 ADIPOQ, ALB, APOE, ELOVL5, HSP90B1, PTGS2, SREBF1
extracellular space 9 ADIPOQ, ALB, APOB, APOE, BDNF, CXCL8, F2, INS, NGF
lysosomal lumen 1 APOB
perinuclear region of cytoplasm 3 BDNF, HSP90B1, PPARG
mitochondrion 2 CYP1B1, FADS1
protein-containing complex 4 ALB, HSP90B1, PTGS2, SREBF1
intracellular membrane-bounded organelle 6 APOB, CYP1B1, FADS1, GPRC5A, PPARG, PTGS1
Microsome membrane 3 CYP1B1, PTGS1, PTGS2
Secreted 10 ADIG, ADIPOQ, ALB, APOB, APOE, BDNF, CXCL8, F2, INS, NGF
extracellular region 11 ADIG, ADIPOQ, ALB, APOB, APOE, BDNF, CXCL8, F2, HSP90B1, INS, NGF
Single-pass membrane protein 1 ADIG
anchoring junction 1 ALB
photoreceptor outer segment 1 PTGS1
Endosome, multivesicular body 1 APOE
Extracellular vesicle 1 APOE
Secreted, extracellular space, extracellular matrix 1 APOE
chylomicron 2 APOB, APOE
high-density lipoprotein particle 1 APOE
low-density lipoprotein particle 2 APOB, APOE
multivesicular body 1 APOE
very-low-density lipoprotein particle 2 APOB, APOE
nucleolus 1 GPRC5A
midbody 1 HSP90B1
Early endosome 2 APOB, APOE
vesicle 1 GPRC5A
focal adhesion 1 HSP90B1
extracellular matrix 1 APOE
collagen trimer 1 ADIPOQ
collagen-containing extracellular matrix 4 ADIPOQ, APOE, F2, HSP90B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
receptor complex 2 GPRC5A, PPARG
neuron projection 2 PTGS1, PTGS2
ciliary basal body 1 ALB
chromatin 2 PPARG, SREBF1
centriole 1 ALB
Secreted, extracellular space 1 APOE
spindle pole 1 ALB
blood microparticle 3 ALB, APOE, F2
nuclear envelope 1 SREBF1
Endomembrane system 1 PTGS1
endosome lumen 3 APOB, INS, NGF
Lipid droplet 2 ADIG, APOB
[Isoform 1]: Endoplasmic reticulum membrane 1 FADS1
Cytoplasmic vesicle membrane 2 GPRC5A, SREBF1
Cell projection, dendrite 1 ELOVL5
Melanosome 2 APOE, HSP90B1
sperm plasma membrane 1 HSP90B1
secretory granule lumen 1 INS
Golgi lumen 3 F2, INS, NGF
endoplasmic reticulum lumen 8 ALB, APOB, APOE, BDNF, F2, HSP90B1, INS, PTGS2
platelet alpha granule lumen 1 ALB
transport vesicle 1 INS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
endoplasmic reticulum exit site 1 APOB
ER to Golgi transport vesicle membrane 1 SREBF1
clathrin-coated endocytic vesicle membrane 2 APOB, APOE
Sarcoplasmic reticulum lumen 1 HSP90B1
synaptic cleft 1 APOE
[Isoform 2]: Endoplasmic reticulum membrane 1 FADS1
Cytoplasmic vesicle, COPII-coated vesicle membrane 1 SREBF1
discoidal high-density lipoprotein particle 1 APOE
endocytic vesicle lumen 3 APOB, APOE, HSP90B1
chylomicron remnant 2 APOB, APOE
intermediate-density lipoprotein particle 2 APOB, APOE
lipoprotein particle 1 APOE
multivesicular body, internal vesicle 1 APOE
mature chylomicron 1 APOB
endoplasmic reticulum chaperone complex 1 HSP90B1
[Neurotrophic factor BDNF precursor form]: Secreted 1 BDNF
[Sterol regulatory element-binding protein 1]: Endoplasmic reticulum membrane 1 SREBF1
[Processed sterol regulatory element-binding protein 1]: Nucleus 1 SREBF1
[Isoform SREBP-1aDelta]: Nucleus 1 SREBF1
[Isoform SREBP-1cDelta]: Nucleus 1 SREBF1
dendritic tree 1 ELOVL5
ciliary transition fiber 1 ALB


文献列表

  • Emily G Oakes, Iliyan Vlasakov, Gregory Kotler, Vadim Bubes, Samia Mora, Raju Tatituri, Nancy R Cook, JoAnn E Manson, Karen H Costenbader. Joint effects of one year of marine omega-3 fatty acid supplementation and participant dietary fish intake upon circulating lipid mediators of inflammation resolution in a randomized controlled trial. Nutrition (Burbank, Los Angeles County, Calif.). 2024 Jul; 123(?):112413. doi: 10.1016/j.nut.2024.112413. [PMID: 38518540]
  • Qian Liu, Yan Liu, Junying Zhao, Weicang Qiao, Juncai Hou, Yaling Wang, Minghui Zhang, Ge Jia, Yan Liu, Xiaofei Fan, Ziqi Li, Haidong Jia, Xiaojiang Zhao, Lijun Chen. Impact of manufacturing processes on glycerolipid and polar lipid composition and ultrastructure in infant formula. Food chemistry. 2024 Jun; 444(?):138623. doi: 10.1016/j.foodchem.2024.138623. [PMID: 38309081]
  • Jhony Robson de Oliveira, Aline Beatriz Mahler Pereira, Henrique Ismarsi de Souza, Wanessa Maria Dos Santos, Thaís Sorares Farnesi de Assunção, Fernanda Bernadelli de Vito, Helio Moraes de Souza, Paulo Roberto da Silva, Marcos Vinicius da Silva, Virmondes Rodrigues Junior, Alexandre Paula Rogerio. Anti-inflammatory actions of aspirin-triggered resolvin D1 (AT-RvD1) in bronchial epithelial cells stimulated by cigarette smoke extract. Prostaglandins & other lipid mediators. 2024 Jun; 172(?):106833. doi: 10.1016/j.prostaglandins.2024.106833. [PMID: 38460760]
  • Maria G Balta, Olav Schreurs, Inger Johanne Schytte Blix, Karl Schenck. The effect of resolvin D1n-3 DPA on primary oral epithelial cell migration in vitro. European journal of oral sciences. 2024 Jun; 132(3):e12981. doi: 10.1111/eos.12981. [PMID: 38403843]
  • Wenyan Zhang, Suwas Bhandari, Yajun Ding, Jun Luo, Bo Feng, Yating Jiang, Ting Chen, Jinling Wei, Xiaodong Pan, Haixu Weng, Zhangna Ding, Jie Chen, Xi Chen, Yuqiang Gong, Hui Li, Shengwei Jin, Yu Hao. Polyunsaturated fatty acid-derived lipid mediator Resolvin D1 alleviates sepsis-induced disseminated intravascular coagulation via Caspase-1/Gasdermin D pyroptotic pathway. Clinical nutrition (Edinburgh, Scotland). 2024 Jun; 43(6):1372-1383. doi: 10.1016/j.clnu.2024.04.020. [PMID: 38678822]
  • Chi-Hei Ip, Hibiki Higuchi, Chang-Yu Wu, Tomoyo Okuda, Shohei Katsuya, Jun Ogawa, Akinori Ando. Production of docosahexaenoic acid by a novel isolated Aurantiochytrium sp. 6-2 using fermented defatted soybean as a nitrogen source for sustainable fish feed development. Bioscience, biotechnology, and biochemistry. 2024 May; 88(6):696-704. doi: 10.1093/bbb/zbae035. [PMID: 38520162]
  • Assamae Chabni, Blanca Pardo de Donlebún, Marina Romero, Carlos F Torres. Predigested Mixture of Arachidonic and Docosahexaenoic Acids for Better Bio-Accessibility. Marine drugs. 2024 May; 22(5):. doi: 10.3390/md22050224. [PMID: 38786615]
  • John J Miklavcic, Natalie Paterson, Jennifer Hahn-Holbrook, Laura Glynn. Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study. JPEN. Journal of parenteral and enteral nutrition. 2024 May; 48(4):479-485. doi: 10.1002/jpen.2628. [PMID: 38566550]
  • Xiaodan Wang, Huiquan Zhu, Baorong Chen, Yumeng Zhang, Akke Kok, Ariette van Knegsel, Shuwen Zhang, Xiaoyang Pang, Shilong Jiang, Bas Kemp, Jing Lu, Jiaping Lv. Effects of endogenous DHA milk and exogenous DHA milk on oxidative stress and cognition in SAMP8 mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 May; 174(?):116467. doi: 10.1016/j.biopha.2024.116467. [PMID: 38531120]
  • Bodo Speckmann, Tanja Wagner, Paul M Jordan, Oliver Werz, Manfred Wilhelm, Heike Tom Dieck, Christiane Schön. Synbiotic Bacillus megaterium DSM 32963 and n-3 PUFA Salt Composition Elevates Pro-Resolving Lipid Mediator Levels in Healthy Subjects: A Randomized Controlled Study. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091354. [PMID: 38732601]
  • Lena Hong, Peter Zahradka, Carla G Taylor. Differential Modulation by Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) of Mesenteric Fat and Macrophages and T Cells in Adipose Tissue of Obese fa/fa Zucker Rats. Nutrients. 2024 Apr; 16(9):. doi: 10.3390/nu16091311. [PMID: 38732558]
  • Huiping Wu, Na Li, Shuang Peng, Haiyan Fu, Zhansheng Hu, Longxiang Su. Maresin1 improves hippocampal neuroinflammation and cognitive function in septic rats by activating the SLC7A11 / GPX4 ferroptosis signaling pathway. International immunopharmacology. 2024 Apr; 131(?):111792. doi: 10.1016/j.intimp.2024.111792. [PMID: 38484667]
  • Yiping Dong, Congcong Luo, Ning Zhang, Ruonan You, Qiang Yuan, Wuyin Li, Ying Zhang. [Correlation between combined deflection angle classification adduction typing and complications after internal fixation of adduction femoral neck fracture]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 2024 Apr; 38(4):405-411. doi: 10.7507/1002-1892.202401063. [PMID: 38632058]
  • Hesen Tang, Zhengjie Liu, Guangmei Han, Junlong Geng, Bianhua Liu, Ruilong Zhang, Zhongping Zhang. Unexpected omega-3 activities in intracellular lipolysis and macrophage foaming revealed by fluorescence lifetime imaging. Proceedings of the National Academy of Sciences of the United States of America. 2024 Apr; 121(15):e2321255121. doi: 10.1073/pnas.2321255121. [PMID: 38564632]
  • Chizuko Maruyama, Miya Uchiyama, Ariko Umezawa, Aoi Tokunaga, Akari Yasuda, Kanako Chibai, Chieko Fukuda, Rina Ichiki, Noriko Kameyama, Masakazu Shinohara. A Cross-Sectional Pilot Study on Association of Ready-to-Eat and Processed Food Intakes with Metabolic Factors, Serum Trans Fat and Phospholipid Fatty Acid Compositions in Healthy Japanese Adults. Nutrients. 2024 Apr; 16(7):. doi: 10.3390/nu16071032. [PMID: 38613065]
  • Siyuan Zhu, Jingbo Liu, Qi Wang, Yong Yang, Lei Du, Xiaoyu Qiu, Renli Qi, Jing Wang. Resolvin D1 alleviates apoptosis triggered by endoplasmic reticulum stress in IPEC-J2 cells. BMC veterinary research. 2024 Apr; 20(1):125. doi: 10.1186/s12917-023-03820-z. [PMID: 38561794]
  • Yu-Lei Jia, Ying Zhang, Lu-Wei Xu, Zi-Xu Zhang, Ying-Shuang Xu, Wang Ma, Yang Gu, Xiao-Man Sun. Enhanced fatty acid storage combined with the multi-factor optimization of fermentation for high-level production of docosahexaenoic acid in Schizochytrium sp. Bioresource technology. 2024 Apr; 398(?):130532. doi: 10.1016/j.biortech.2024.130532. [PMID: 38447618]
  • Wenting Wei, Siyan Yu, Huanting Zeng, Weifeng Tan, Manjiang Hu, Jie Huang, Xudong Li, Limei Mao. Docosahexaenoic and Eicosapentaenoic Acids Promote the Accumulation of Browning-Related Myokines via Calcium Signaling in Insulin-Resistant Mice. The Journal of nutrition. 2024 Apr; 154(4):1271-1281. doi: 10.1016/j.tjnut.2024.02.016. [PMID: 38367811]
  • Guofu Zhao, Ming Chen, Jingwen Liu, Shang Wang, Dongmei Fu, Chunzhi Zhang. Concentration-dependent dual roles of proanthocyanidins on oxidative stress and docosahexaenoic acid production in Schizochytrium sp. ATCC 20888. Bioresource technology. 2024 Apr; 398(?):130537. doi: 10.1016/j.biortech.2024.130537. [PMID: 38452955]
  • Yan Sun, Shujun Sun, Pu Chen, Yan Dai, Dong Yang, Yun Lin, Lisha Yi. Maresins as novel anti-inflammatory actors and putative therapeutic targets in sepsis. Pharmacological research. 2024 Apr; 202(?):107113. doi: 10.1016/j.phrs.2024.107113. [PMID: 38387744]
  • Leslie Couëdelo, Stephanie Lennon, Hélène Abrous, Ikram Chamekh, Corentin Bouju, Hugues Griffon, Carole Vaysse, Lionel Larvol, Gildas Breton. In Vivo Absorption and Lymphatic Bioavailability of Docosahexaenoic Acid from Microalgal Oil According to Its Physical and Chemical Form of Vectorization. Nutrients. 2024 Mar; 16(7):. doi: 10.3390/nu16071014. [PMID: 38613047]
  • Pengjie Wang, Panqiao Chen, Xiaoxu Zhang, Ignatius Man-Yau Szeto, Fang Li, Shengjie Tan, Genna Ba, Yan Zhang, Sufang Duan, Yue Yang. Bioaccessibility of docosahexaenoic acid in naturally and artificially enriched milk. Food chemistry. 2024 Mar; 437(Pt 1):137772. doi: 10.1016/j.foodchem.2023.137772. [PMID: 37871424]
  • Ivana Djuricic, Philip C Calder. Omega-3 (n-3) Fatty Acid-Statin Interaction: Evidence for a Novel Therapeutic Strategy for Atherosclerotic Cardiovascular Disease. Nutrients. 2024 Mar; 16(7):. doi: 10.3390/nu16070962. [PMID: 38612996]
  • Sangsu Bang, Changyu Jiang, Jing Xu, Sharat Chandra, Aidan McGinnis, Xin Luo, Qianru He, Yize Li, Zilong Wang, Xiang Ao, Marc Parisien, Lorenna Oliveira Fernandes de Araujo, Sahel Jahangiri Esfahani, Qin Zhang, Raquel Tonello, Temugin Berta, Luda Diatchenko, Ru-Rong Ji. Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis. The Journal of clinical investigation. 2024 Mar; 134(9):. doi: 10.1172/jci173537. [PMID: 38530364]
  • Romina Gomes, Inês Mendes, Maria Paula Duarte, Narcisa M Bandarra, Ana Gomes-Bispo. New Forms of Neuroactive Phospholipids for DHA Enrichment in Brain. Marine drugs. 2024 Feb; 22(3):. doi: 10.3390/md22030116. [PMID: 38535457]
  • Peng-Yang Liu, Jun-Jie Wu, Gang Li, Chu-Bin Lin, Shan Jiang, Shuang Liu, Xia Wan. The Biosynthesis of Astaxanthin Esters in Schizochytrium sp. is Mediated by a Bifunctional Diacylglycerol Acyltransferase. Journal of agricultural and food chemistry. 2024 Feb; 72(7):3584-3595. doi: 10.1021/acs.jafc.3c09086. [PMID: 38344823]
  • Samuel C R Sherratt, R Preston Mason, Peter Libby, Ph Gabriel Steg, Deepak L Bhatt. Do patients benefit from omega-3 fatty acids?. Cardiovascular research. 2024 02; 119(18):2884-2901. doi: 10.1093/cvr/cvad188. [PMID: 38252923]
  • Elena García-Maldonado, Bélen Zapatera, Alexandra Alcorta, M Pilar Vaquero. A microalgae docosahexaenoic acid supplement does not modify the influence of sex and diet on iron status in Spanish vegetarians or omnivores: A randomized placebo-controlled crossover study. Nutrition (Burbank, Los Angeles County, Calif.). 2024 Feb; 118(?):112282. doi: 10.1016/j.nut.2023.112282. [PMID: 38042044]
  • Zi-Xu Zhang, Lu-Wei Xu, Ying-Shuang Xu, Jin Li, Wang Ma, Xiao-Man Sun, He Huang. Integration of genetic engineering and multi-factor fermentation optimization for co-production of carotenoid and DHA in Schizochytrium sp. Bioresource technology. 2024 Feb; 394(?):130250. doi: 10.1016/j.biortech.2023.130250. [PMID: 38154734]
  • Haydee E P Bazan, Thang L Pham. A new R,R-RvD6 isomer with protective actions following corneal nerve injury. Prostaglandins & other lipid mediators. 2024 Feb; 170(?):106802. doi: 10.1016/j.prostaglandins.2023.106802. [PMID: 38036037]
  • Ajeet Singh Chauhan, Anil Kumar Patel, Reeta Rani Singhania, Akash Pralhad Vadrale, Chiu-Wen Chen, Balendu Sheker Giri, Jo-Shu Chang, Cheng-Di Dong. Fine-tuning of key parameters to enhance biomass and nutritional polyunsaturated fatty acids production from Thraustochytrium sp. Bioresource technology. 2024 Feb; 394(?):130252. doi: 10.1016/j.biortech.2023.130252. [PMID: 38145766]
  • Irene Cetin, Susan E Carlson, Christy Burden, Eduardo B da Fonseca, Gian Carlo di Renzo, Adamos Hadjipanayis, William S Harris, Kishore R Kumar, Sjurdur Frodi Olsen, Silke Mader, Fionnuala M McAuliffe, Beverly Muhlhausler, Emily Oken, Liona C Poon, Lucilla Poston, Usha Ramakrishnan, Charles C Roehr, Charles Savona-Ventura, Cornelius M Smuts, Alexandros Sotiriadis, Kuan-Pin Su, Rachel M Tribe, Gretchen Vannice, Berthold Koletzko. Omega-3 fatty acid supply in pregnancy for risk reduction of preterm and early preterm birth. American journal of obstetrics & gynecology MFM. 2024 Feb; 6(2):101251. doi: 10.1016/j.ajogmf.2023.101251. [PMID: 38070679]
  • Zeyan Chen, Yonghui Kong, Zishu Huang, Xiaoyu Zheng, Zhihong Zheng, Defu Yao, Shen Yang, Yueling Zhang, Jude Juventus Aweya. Exogenous alpha-linolenic acid and Vibrio parahaemolyticus induce EPA and DHA levels mediated by delta-6 desaturase to enhance shrimp immunity. International journal of biological macromolecules. 2024 Feb; 257(Pt 2):128583. doi: 10.1016/j.ijbiomac.2023.128583. [PMID: 38056755]
  • Jingnan Lei, Yuan He, Shuang Zhu, Jiachen Shi, Chin-Ping Tan, Yuanfa Liu, Yong-Jiang Xu. SpecLipIDA: a pseudotargeted lipidomics approach for polyunsaturated fatty acids in milk. The Analyst. 2024 Jan; 149(3):751-760. doi: 10.1039/d3an01536j. [PMID: 38194259]
  • Maede Hasanpour, Ali Rezaie, Milad Iranshahy, Mojtaba Yousefi, Satar Saberi, Mehrdad Iranshahi. 1H NMR-based metabolomics study of the lipid profile of omega-3 fatty acid supplements and some vegetable oils. Journal of pharmaceutical and biomedical analysis. 2024 Jan; 238(?):115848. doi: 10.1016/j.jpba.2023.115848. [PMID: 37948777]
  • Yan Su, Yunjon Han, Hack Sun Choi, Gil-Yong Lee, Hee Won Cho, Heonsik Choi, Jong Hyun Choi, Yong-Suk Jang, Jeong-Woo Seo. Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase attenuate RANKL-induced osteoclast differentiation and rheumatoid arthritis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2024 Jan; 171(?):116153. doi: 10.1016/j.biopha.2024.116153. [PMID: 38232664]
  • Zachary Hoover, Michael Lynn, Kiryl Zhaliazka, Aidan P Holman, Tianyi Dou, Dmitry Kurouski. Long-Chain Polyunsaturated Fatty Acids Accelerate the Rate of Insulin Aggregation and Enhance Toxicity of Insulin Aggregates. ACS chemical neuroscience. 2024 Jan; 15(1):147-154. doi: 10.1021/acschemneuro.3c00583. [PMID: 38127718]
  • Adam H Metherel, Brinley J Klievik, Giulia Cisbani, Mackenzie E Smith, Greg Cumberford, Richard P Bazinet. Blood and tissue docosahexaenoic acid (DHA, 22:6n-3) turnover rates from Ahiflower® oil are not different than from DHA ethyl ester oil in a diet switch mouse model. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2024 Jan; 1869(1):159422. doi: 10.1016/j.bbalip.2023.159422. [PMID: 37977491]
  • Ateequr Rehman, Van Pham, Nicole Seifert, Nathalie Richard, Wilbert Sybesma, Robert E Steinert. The Polyunsaturated Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid, and Vitamin K1 Modulate the Gut Microbiome: A Study Using an In Vitro Shime Model. Journal of dietary supplements. 2024; 21(2):135-153. doi: 10.1080/19390211.2023.2198007. [PMID: 37078491]
  • Sheetal Mane, Purnima Kumari, Anupama Singh, Neetu Kumra Taneja, Rajni Chopra. Amelioration for oxidative stability and bioavailability of N-3 PUFA enriched microalgae oil: an overview. Critical reviews in food science and nutrition. 2024; 64(9):2579-2600. doi: 10.1080/10408398.2022.2124505. [PMID: 36128949]
  • Hao Liu, Nana Li, Ge Kuang, Xia Gong, Ting Wang, Jun Hu, Hui Du, Minxuan Zhong, Jiashi Guo, Yao Xie, Yang Xiang, Shengwang Wu, Yiling Yuan, Xinru Yin, Jingyuan Wan, Ke Li. Protectin D1 inhibits TLR4 signaling pathway to alleviate non-alcoholic steatohepatitis via upregulating IRAK-M. Free radical biology & medicine. 2024 Jan; 210(?):42-53. doi: 10.1016/j.freeradbiomed.2023.11.011. [PMID: 37984750]
  • X-W Huang, S-W Pang, L-Z Yang, T Han, J-M Chen, C-W Huang, L Liao, P-J Xie. TNFSF14 mediates the impact of docosahexaenoic acid on atopic dermatitis: a Mendelian randomization study. European review for medical and pharmacological sciences. 2024 Jan; 28(1):107-117. doi: 10.26355/eurrev_202401_34896. [PMID: 38235898]
  • Gerard Marrugat, Ainara Cano, Javier Amézaga, Sara Arranz, Nieves Embade, Óscar Millet, Carla Ferreri, Itziar Tueros. Effect of age and dietary habits on Red Blood Cell membrane fatty acids in a Southern Europe population (Basque Country). Prostaglandins, leukotrienes, and essential fatty acids. 2024 Jan; 200(?):102602. doi: 10.1016/j.plefa.2023.102602. [PMID: 38147804]
  • Yana Liu, Xiao Han, Yujie Dai, Zhi Chen. bZIP transcription factor FabR: Redox-dependent mechanism controlling docosahexaenoic acid biosynthesis and H2O2 stress response in Schizochytrium sp. Free radical biology & medicine. 2024 01; 210(?):246-257. doi: 10.1016/j.freeradbiomed.2023.11.027. [PMID: 38042223]
  • Archana S Rao, Ajay Nair, K Nivetha, Bibi Ayesha, Kapadia Hardi, Vora Divya, S M Veena, K S Anantharaju, Sunil S More. Impacts of Omega-3 Fatty Acids, Natural Elixirs for Neuronal Health, on Brain Development and Functions. Methods in molecular biology (Clifton, N.J.). 2024; 2761(?):209-229. doi: 10.1007/978-1-0716-3662-6_15. [PMID: 38427239]
  • Chun-Xiao Yan, Ying Zhang, Wen-Qian Yang, Wang Ma, Xiao-Man Sun, He Huang. Universal and unique strategies for the production of polyunsaturated fatty acids in industrial oleaginous microorganisms. Biotechnology advances. 2024 Jan; 70(?):108298. doi: 10.1016/j.biotechadv.2023.108298. [PMID: 38048920]
  • Yusuke Kobayashi, Tetsuya Fujikawa, Aiko Haruna, Rina Kawano, Moe Ozawa, Tatsuya Haze, Shiro Komiya, Shota Suzuki, Yuki Ohki, Akira Fujiwara, Sanae Saka, Nobuhito Hirawa, Yoshiyuki Toya, Kouichi Tamura. Omega-3 Fatty Acids Reduce Remnant-like Lipoprotein Cholesterol and Improve the Ankle-Brachial Index of Hemodialysis Patients with Dyslipidemia: A Pilot Study. Medicina (Kaunas, Lithuania). 2023 Dec; 60(1):. doi: 10.3390/medicina60010075. [PMID: 38256336]
  • Hai-Tao Yu, Jia-Yu Gong, Wen-Hui Xu, Yi-Ru Chen, Yue-Ting Li, Yi-Fei Chen, Guo-Liang Liu, Hai-Ying Zhang, Lin Xie. Gestational Diabetes Mellitus Remodels the Fetal Brain Fatty Acid Profile Through Placenta-Brain Lipid Axis in C57BL/6J Mice. The Journal of nutrition. 2023 Dec; ?(?):. doi: 10.1016/j.tjnut.2023.12.045. [PMID: 38159812]
  • Jesus A Castor-Macias, Jacqueline A Larouche, Emily C Wallace, Bonnie D Spence, Alec Eames, Pamela Duran, Benjamin A Yang, Paula M Fraczek, Carol A Davis, Susan V Brooks, Krishna Rao Maddipati, James F Markworth, Carlos A Aguilar. Maresin 1 repletion improves muscle regeneration after volumetric muscle loss. eLife. 2023 Dec; 12(?):. doi: 10.7554/elife.86437. [PMID: 38131691]
  • Marlon Vincent V Duro, Juno Van Valkenburgh, Diana E Ingles, Jenny Tran, Zhiheng Cai, Brandon Ebright, Shaowei Wang, Bilal E Kerman, Jasmin Galvan, Sung Hee Hwang, Naomi S Sta Maria, Francesca Zanderigo, Etienne Croteau, Stephen C Cunnane, Stanley I Rapoport, Stan G Louie, Russell E Jacobs, Hussein N Yassine, Kai Chen. Synthesis and Preclinical Evaluation of 22-[18F]Fluorodocosahexaenoic Acid as a Positron Emission Tomography Probe for Monitoring Brain Docosahexaenoic Acid Uptake Kinetics. ACS chemical neuroscience. 2023 Dec; 14(24):4409-4418. doi: 10.1021/acschemneuro.3c00681. [PMID: 38048230]
  • Mathilde Cancalon, Youna M Hemery, Nathalie Barouh, Bruno Baréa, Claire Berton-Carabin, Lucie Birault, Erwann Durand, Pierre Villeneuve, Claire Bourlieu-Lacanal. Comparison of the effect of various sources of saturated fatty acids on infant follow-on formulas oxidative stability and nutritional profile. Food chemistry. 2023 Dec; 429(?):136854. doi: 10.1016/j.foodchem.2023.136854. [PMID: 37531873]
  • Ella J Baker. Alternative sources of bioactive omega-3 fatty acids: what are the options?. Current opinion in clinical nutrition and metabolic care. 2023 Dec; ?(?):. doi: 10.1097/mco.0000000000001006. [PMID: 38126230]
  • Tamil Selvi Sundaram, Maria Filippa Addis, Carlotta Giromini, Raffaella Rebucci, Salvatore Pisanu, Daniela Pagnozzi, Antonella Baldi. Comprehensive proteomic analysis reveals omega-3 fatty acids to counteract endotoxin-stimulated metabolic dysregulation in porcine enterocytes. Scientific reports. 2023 12; 13(1):21595. doi: 10.1038/s41598-023-48018-3. [PMID: 38062040]
  • Siqing Mao, Ziling Liu, Yuan Tian, Dan Li, Xin Gao, Yanqiong Wen, Tao Peng, Weijun Shen, Dingfu Xiao, Fachun Wan, Lei Liu. Branched-Long-Chain Monomethyl Fatty Acids: Are They Hidden Gems?. Journal of agricultural and food chemistry. 2023 Dec; 71(48):18674-18684. doi: 10.1021/acs.jafc.3c06300. [PMID: 37982580]
  • Xiurong Zhang, Hongting Zhang. Pro-resolving and anti-inflammatory effects of resolvins and protectins in rheumatoid arthritis. Inflammopharmacology. 2023 Dec; 31(6):2995-3004. doi: 10.1007/s10787-023-01343-5. [PMID: 37831392]
  • Åsmund Stenvik Haatveit, Trond Vidar Hansen. The biosynthetic pathways of the protectins. Prostaglandins & other lipid mediators. 2023 12; 169(?):106787. doi: 10.1016/j.prostaglandins.2023.106787. [PMID: 37806439]
  • Mianmian Zhu, Rongyue Sun, Lixu Jin, Dandan Yu, Xiaoxia Huang, Ting Zhu, Yujing Gong, Yuan Chen, Jiamin Shi, Qiu Wang, Chaosheng Lu, Dan Wang. Metabolomics profiling of maternal and umbilical cord blood in normoglycemia macrosomia. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2023 Dec; 36(2):2270761. doi: 10.1080/14767058.2023.2270761. [PMID: 37848386]
  • Almar Neiteler, Anwar A Palakkan, Kevin M Gallagher, James A Ross. Oxidative stress and docosahexaenoic acid injury lead to increased necroptosis and ferroptosis in retinal pigment epithelium. Scientific reports. 2023 11; 13(1):21143. doi: 10.1038/s41598-023-47721-5. [PMID: 38036571]
  • Karina Ervik, Amalie F Reinertsen, Duco S Koenis, Jesmond Dalli, Trond V Hansen. Stereoselective Synthesis, Pro-resolution, and Anti-inflammatory Actions of RvD5n-3 DPA. Journal of natural products. 2023 11; 86(11):2546-2553. doi: 10.1021/acs.jnatprod.3c00769. [PMID: 37879110]
  • Patricia Monge, Alma M Astudillo, Laura Pereira, María A Balboa, Jesús Balsinde. Dynamics of Docosahexaenoic Acid Utilization by Mouse Peritoneal Macrophages. Biomolecules. 2023 11; 13(11):. doi: 10.3390/biom13111635. [PMID: 38002317]
  • Chenchen Bian, Xiangtong Yuan, Caihong Zeng, Jian Sun, Gen Kaneko, Hong Ji. Docosahexaenoic acid (DHA) inhibits abdominal fat accumulation by promoting adipocyte apoptosis though PPARγ-LC3-BNIP3 pathway-mediated mitophagy. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023 Nov; ?(?):159425. doi: 10.1016/j.bbalip.2023.159425. [PMID: 37952912]
  • Pilar Irún, Patricia Carrera-Lasfuentes, Marta Sánchez-Luengo, Úrsula Belio, María José Domper-Arnal, Gustavo A Higuera, Malena Hawkins, Xavier de la Rosa, Angel Lanas. Pharmacokinetics and Changes in Lipid Mediator Profiling after Consumption of Specialized Pro-Resolving Lipid-Mediator-Enriched Marine Oil in Healthy Subjects. International journal of molecular sciences. 2023 Nov; 24(22):. doi: 10.3390/ijms242216143. [PMID: 38003333]
  • Cheng Wei, Jishou Zhang, Shanshan Peng, Jianfang Liu, Yao Xu, Mengmeng Zhao, Shuwan Xu, Wei Pan, Zheng Yin, Zihui Zheng, Juan-Juan Qin, Jun Wan, Menglong Wang. Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway. Journal of hypertension. 2023 Nov; ?(?):. doi: 10.1097/hjh.0000000000003610. [PMID: 37937508]
  • Mirielle L Pauline, Caitlin Huynh, Pamela R Wizzard, Patrick N Nation, Catherine J Field, Paul W Wales, Justine M Turner. In parenteral nutrition-fed piglets, fatty acids vary by lipid emulsion and tissue sampled. JPEN. Journal of parenteral and enteral nutrition. 2023 11; 47(8):1038-1046. doi: 10.1002/jpen.2547. [PMID: 37416983]
  • Pranesha Prabhakaran, Mohamed Yusuf Mohamed Nazir, Roypim Thananusak, Aidil Abdul Hamid, Wanwipa Vongsangnak, Yuanda Song. Uncovering global lipid accumulation routes towards docosahexaenoic acid (DHA) production in Aurantiochytrium sp. SW1 using integrative proteomic analysis. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2023 11; 1868(11):159381. doi: 10.1016/j.bbalip.2023.159381. [PMID: 37625782]
  • Ritchie Ly, Brittany C MacIntyre, Stuart M Philips, Chris McGlory, David M Mutch, Philip Britz-McKibbin. Lipidomic studies reveal two specific circulating phosphatidylcholines as surrogate biomarkers of the omega-3 index. Journal of lipid research. 2023 11; 64(11):100445. doi: 10.1016/j.jlr.2023.100445. [PMID: 37730162]
  • Ariadna Pinar-Martí, Silvia Fernández-Barrés, Florence Gignac, Cecilia Persavento, Anna Delgado, Dora Romaguera, Iolanda Lázaro, Emilio Ros, Mònica López-Vicente, Jordi Salas-Salvadó, Aleix Sala-Vila, Jordi Júlvez. Red blood cell omega-3 fatty acids and attention scores in healthy adolescents. European child & adolescent psychiatry. 2023 Nov; 32(11):2187-2195. doi: 10.1007/s00787-022-02064-w. [PMID: 35960396]
  • Daniëlle Swinkels, Sai Kocherlakota, Yannick Das, Adriaan D Dane, Eric J M Wever, Frédéric M Vaz, Nicolas G Bazan, Paul P Van Veldhoven, Myriam Baes. DHA Shortage Causes the Early Degeneration of Photoreceptors and RPE in Mice With Peroxisomal β-Oxidation Deficiency. Investigative ophthalmology & visual science. 2023 11; 64(14):10. doi: 10.1167/iovs.64.14.10. [PMID: 37934161]
  • Pradnya Gurav, Suraj Garad, Kedar R N. n-3 PUFAs Show Promise as Adjuvants in Chemotherapy, Enhancing their Efficacy while Safeguarding Hematopoiesis and Promoting Bone Generation. Current topics in medicinal chemistry. 2023 Oct; ?(?):. doi: 10.2174/0115680266258838231020102401. [PMID: 37907485]
  • Xin Zhang, Tian Yuan, Xuhui Chen, Xuebo Liu, Jun Hu, Zhigang Liu. Effects of DHA on cognitive dysfunction in aging and Alzheimer's disease: The mediating roles of ApoE. Progress in lipid research. 2023 Oct; 93(?):101256. doi: 10.1016/j.plipres.2023.101256. [PMID: 37890592]
  • Luis Alberto Videla, Rodrigo Valenzuela, Andrea Del Campo, Jessica Zúñiga-Hernández. Omega-3 Lipid Mediators: Modulation of the M1/M2 Macrophage Phenotype and Its Protective Role in Chronic Liver Diseases. International journal of molecular sciences. 2023 Oct; 24(21):. doi: 10.3390/ijms242115528. [PMID: 37958514]
  • Yan-Fang Chen, Ze-Kai Fan, Xiang Gao, Fang Zhou, Xiao-Fei Guo, Andrew J Sinclair, Duo Li. n-3 polyunsaturated fatty acids in phospholipid or triacylglycerol form attenuate nonalcoholic fatty liver disease via mediating cannabinoid receptor 1/adiponectin/ceramide pathway. The Journal of nutritional biochemistry. 2023 Oct; 123(?):109484. doi: 10.1016/j.jnutbio.2023.109484. [PMID: 37866428]
  • Akiko Harauma, Hajime Yoshihara, Yukino Hoshi, Kei Hamazaki, Toru Moriguchi. Effects of Varied Omega-3 Fatty Acid Supplementation on Postpartum Mental Health and the Association between Prenatal Erythrocyte Omega-3 Fatty Acid Levels and Postpartum Mental Health. Nutrients. 2023 Oct; 15(20):. doi: 10.3390/nu15204388. [PMID: 37892462]
  • Owen Tyoe, Chinta Aryal, Jiajie Diao. Docosahexaenoic acid promotes vesicle clustering mediated by alpha-Synuclein via electrostatic interaction. The European physical journal. E, Soft matter. 2023 Oct; 46(10):96. doi: 10.1140/epje/s10189-023-00353-z. [PMID: 37823961]
  • Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki. Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder. Journal of lipid research. 2023 Oct; ?(?):100458. doi: 10.1016/j.jlr.2023.100458. [PMID: 37838304]
  • Eija Ahonen, Annelie Damerau, Kaisa M Linderborg. Antioxidative Effect of Dihydrosphingosine (d18:0) and α-Tocopherol on Tridocosahexaenoin (DHA-TAG). Journal of agricultural and food chemistry. 2023 Oct; 71(40):14769-14781. doi: 10.1021/acs.jafc.3c02668. [PMID: 37751317]
  • Łukasz Kołodziej, Piotr Lech Czarny, Sylwia Ziółkowska, Katarzyna Białek, Janusz Szemraj, Piotr Gałecki, Kuan-Pin Su, Tomasz Śliwiński. How fish consumption prevents the development of Major Depressive Disorder? A comprehensive review of the interplay between n-3 PUFAs, LTP and BDNF. Progress in lipid research. 2023 Oct; 92(?):101254. doi: 10.1016/j.plipres.2023.101254. [PMID: 37820872]
  • Zeynep Celik, Gulsev Ozen, Seynur Sunar, Saygın Türkyılmaz, Gülsüm Türkyılmaz, Ali Aycan Kavala, Önder Teskin, B Sönmez Uydeş Doğan, Gokce Topal. Effect of specialized pro-resolving lipid mediators in the regulation of vascular tone and inflammation in human saphenous vein. Prostaglandins & other lipid mediators. 2023 Oct; ?(?):106786. doi: 10.1016/j.prostaglandins.2023.106786. [PMID: 37806440]
  • Mikala M Zelows, Corissa Cady, Nikitha Dharanipragada, Anna E Mead, Zachary A Kipp, Evelyn A Bates, Venkateshwari Varadharajan, Rakhee Banerjee, Se-Hyung Park, Nathan R Shelman, Harrison A Clarke, Tara R Hawkinson, Terrymar Medina, Ramon C Sun, Todd A Lydic, Terry D Hinds, J Mark Brown, Samir Softic, Gregory A Graf, Robert N Helsley. Loss of carnitine palmitoyltransferase 1a reduces docosahexaenoic acid-containing phospholipids and drives sexually dimorphic liver disease in mice. Molecular metabolism. 2023 Oct; 78(?):101815. doi: 10.1016/j.molmet.2023.101815. [PMID: 37797918]
  • Shih-Yi Lin, Ya-Yu Wang, Pin-Ho Pan, Jiaan-Der Wang, Ching-Ping Yang, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Yu-Li Lo, Yih-Hsin Chang, Chun-Jung Chen. DHA Alleviated Hepatic and Adipose Inflammation with Increased Adipocyte Browning in High-Fat Diet-Induced Obese Mice. The Journal of nutritional biochemistry. 2023 Oct; ?(?):109457. doi: 10.1016/j.jnutbio.2023.109457. [PMID: 37797731]
  • Makoto Miyoshi, Makoto Usami, Yuya Nishiyama, Motoki Kai, Ayumi Suzuki, Noriaki Maeshige, Atomu Yamaguchi, Xiaoqi Ma, Masakazu Shinohara. Soleus muscle contains a higher concentration of lipid metabolites than extensor digitorum longus in rats with lipopolysaccharide-induced acute muscle atrophy. Clinical nutrition ESPEN. 2023 10; 57(?):48-57. doi: 10.1016/j.clnesp.2023.06.011. [PMID: 37739695]
  • Witono Basuki, Rofiq Sunaryanto, Andri Frediansyah, Ika Rahmatul Layly, Yusnitati, Reni Giarni, Abdul Wakhid Shodiq. Isolation and Characterization of Thraustochytrium Trk-23 Producing Docosahexaenoic Acid from North Kalimantan, Indonesia. Pakistan journal of biological sciences : PJBS. 2023 Oct; 26(11):567-575. doi: 10.3923/pjbs.2023.567.575. [PMID: 38193371]
  • Preeti Mehta, Rekha Rani, Ravi Gupta, Anshu Mathur, Sankara Sri Venkata Ramakumar. Simultaneous production of high-value lipids in Schizochytrium sp. by synergism of chemical modulators. Applied microbiology and biotechnology. 2023 Oct; 107(19):6135-6149. doi: 10.1007/s00253-023-12698-8. [PMID: 37555947]
  • Vanessa Javera Castanheira Neia, Deborah Cristina Landi Masquio, Paola Alves Claudino, Pamela Duso, Débora Kanegae Tadano, Marciele Alves Bolognese, Patrícia Magalhães de Souza, Oscar Oliveira Santos, Jesuí Vergílio Visentainer, Bárbara Dal Molin Netto. Lipid profile and cost of enteral nutrition formula with addition of fish oil used in a public hospital. Clinical nutrition ESPEN. 2023 10; 57(?):288-296. doi: 10.1016/j.clnesp.2023.06.007. [PMID: 37739670]
  • Giulia Ferri, Matteo Mucci, Domenico Mattoscio, Antonio Recchiuti. Specialized pro-resolving lipid mediators and resolution of viral diseases. Prostaglandins & other lipid mediators. 2023 10; 168(?):106762. doi: 10.1016/j.prostaglandins.2023.106762. [PMID: 37355222]
  • Gilles Tinant, Mélusine Van Larebeke, Benjamin Lemaire, Marine Courteille, Cécile Gardin, Ineke Neefs, Krishna Das, Melissa M Page, Jean-François Rees, Yvan Larondelle, Cathy Debier. Dietary methylmercury and fatty acids affect the lipid metabolism of adipose tissue and liver in rainbow trout. Aquatic toxicology (Amsterdam, Netherlands). 2023 Oct; 263(?):106673. doi: 10.1016/j.aquatox.2023.106673. [PMID: 37669601]
  • Zi-Lei Chen, Lin-Hui Yang, Shao-Jie He, Yuan-Hang Du, Dong-Sheng Guo. Development of a green fermentation strategy with resource cycle for the docosahexaenoic acid production by Schizochytrium sp. Bioresource technology. 2023 Oct; 385(?):129434. doi: 10.1016/j.biortech.2023.129434. [PMID: 37399951]
  • Kunio Yui, George Imataka, Tadashi Shiohama. Lipid Peroxidation of the Docosahexaenoic Acid/Arachidonic Acid Ratio Relating to the Social Behaviors of Individuals with Autism Spectrum Disorder: The Relationship with Ferroptosis. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914796. [PMID: 37834244]
  • Wasundara Fernando, Rikki F Clark, H P Vasantha Rupasinghe, David W Hoskin, Melanie R Power Coombs. Phloridzin Docosahexaenoate Inhibits Spheroid Formation by Breast Cancer Stem Cells and Exhibits Cytotoxic Effects against Paclitaxel-Resistant Triple Negative Breast Cancer Cells. International journal of molecular sciences. 2023 Sep; 24(19):. doi: 10.3390/ijms241914577. [PMID: 37834020]
  • Hao Chen, Xuebing Leng, Shaohui Liu, Ziqi Zeng, Feng Huang, Rongjie Huang, Yunfeng Zou, Yunan Xu. Association between dietary intake of omega-3 polyunsaturated fatty acids and all-cause and cardiovascular mortality among hypertensive adults: Results from NHANES 1999-2018. Clinical nutrition (Edinburgh, Scotland). 2023 Sep; 42(12):2434-2442. doi: 10.1016/j.clnu.2023.09.011. [PMID: 37871484]
  • Jin Lee, Hyun-Ah Park, Kyung-Chul Shin, Jin-Byung Park, Deok-Kun Oh. Efficient biotransformation of docosahexaenoic acid-rich oils into the lipid mediator resolvin D5 by cells expressing 15S-lipoxygenase using a bioreactor. Bioresource technology. 2023 Sep; ?(?):129750. doi: 10.1016/j.biortech.2023.129750. [PMID: 37717704]
  • Feras Almasri, Manal Badrasawi, Rana Zahdeh, Andreas Hahn, Jan Philipp Schuchardt, Theresa Greupner. Very low Omega-3 Index in young healthy students from Palestine. Lipids. 2023 09; 58(5):209-216. doi: 10.1002/lipd.12375. [PMID: 37300456]
  • Rosalie G J Rietjens, Ton J Rabelink. Unveiling the role of Mfsd2a and LPC-DHA in kidney repair. Journal of lipid research. 2023 09; 64(9):100422. doi: 10.1016/j.jlr.2023.100422. [PMID: 37549789]
  • Nikita Subhash Hinge, Himanshu Kathuria, Murali Monohar Pandey. Rivastigmine-DHA ion-pair complex improved loading in hybrid nanoparticles for better amyloid inhibition and nose-to-brain targeting in Alzheimer's. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2023 Sep; 190(?):131-149. doi: 10.1016/j.ejpb.2023.06.007. [PMID: 37330117]
  • Sayoko Kuroha, Yusaku Katada, Yosuke Isobe, Haruki Uchino, Kyosuke Shishikura, Takashi Nirasawa, Kazuo Tsubota, Kazuno Negishi, Toshihide Kurihara, Makoto Arita. Long chain acyl-CoA synthetase 6 facilitates the local distribution of di-docosahexaenoic acid- and ultra-long-chain-PUFA-containing phospholipids in the retina to support normal visual function in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2023 09; 37(9):e23151. doi: 10.1096/fj.202300976r. [PMID: 37585289]
  • Daniel K Chen, Adam H Metherel, Kimia Rezaei, Camilla Parzanini, Chuck T Chen, Christopher E Ramsden, Mark Horowitz, Keturah R Faurot, Beth MacIntosh, Daisy Zamora, Richard P Bazinet. Analysis of omega-3 and omega-6 polyunsaturated fatty acid metabolism by compound-specific isotope analysis in humans. Journal of lipid research. 2023 09; 64(9):100424. doi: 10.1016/j.jlr.2023.100424. [PMID: 37572791]
  • Natalia Grigorova, Zhenya Ivanova, Ekaterina Vachkova, Valeria Petrova, Toncho Penev. DHA-Provoked Reduction in Adipogenesis and Glucose Uptake Could Be Mediated by Gps2 Upregulation in Immature 3T3-L1 Cells. International journal of molecular sciences. 2023 Aug; 24(17):. doi: 10.3390/ijms241713325. [PMID: 37686130]
  • Yueqi Yang, Xueyan Wang, Lu Chen, Shiben Wang, Jun Han, Zhengping Wang, Min Wen. A Compared Study of Eicosapentaenoic Acid and Docosahexaenoic Acid in Improving Seizure-Induced Cognitive Deficiency in a Pentylenetetrazol-Kindling Young Mice Model. Marine drugs. 2023 Aug; 21(9):. doi: 10.3390/md21090464. [PMID: 37755077]
  • Jin Li, Yi Zheng, Wen-Qian Yang, Zhi-Yun Wei, Ying-Shuang Xu, Zi-Xu Zhang, Wang Ma, Xiao-Man Sun. Enhancing the accumulation of lipid and docosahexaenoic acid in Schizochytrium sp. by co-overexpression of phosphopantetheinyl transferase and ω-3 fatty acid desaturase. Biotechnology journal. 2023 Aug; ?(?):e2300314. doi: 10.1002/biot.202300314. [PMID: 37596914]