Methimazole (BioDeep_00000002534)
Secondary id: BioDeep_00000397481
human metabolite blood metabolite Volatile Flavor Compounds
代谢物信息卡片
化学式: C4H6N2S (114.02516759999999)
中文名称: 2-巯基-1-甲基咪唑(甲硫咪唑), 甲巯咪唑, 2-巯基-1-甲基咪唑
谱图信息:
最多检出来源 Homo sapiens(blood) 0.8%
分子结构信息
SMILES: Cn(c1)c(S)nc1
InChI: InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)
描述信息
A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme. [PubChem]
H - Systemic hormonal preparations, excl. sex hormones and insulins > H03 - Thyroid therapy > H03B - Antithyroid preparations > H03BB - Sulfur-containing imidazole derivatives
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D013956 - Antithyroid Agents
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist > C885 - Antithyroid Agent
CONFIDENCE standard compound; INTERNAL_ID 1166
KEIO_ID M126
同义名列表
56 个代谢物同义名
1-methyl-2,3-dihydro-1H-imidazole-2-thione; 1-METHYL-1,3-dihydro-2H-imidazole-2-thione; Sanofi synthelabo brand OF methimazole; Henning berlin brand OF methimazole; Nourypharma brand OF methimazole; Philopharm brand OF methimazole; 1-Methylimidazole-2(3H)-thione; Eli lilly brand OF methimazole; 2-mercapto-1-methylimidazole; 1-Methyl-2-mercaptoimidazole; Temmler brand OF methimazole; 1 Methyl 2 mercaptoimidazole; Estedi brand OF methimazole; Hexal brand OF methimazole; Jones brand OF methimazole; Merck brand OF methimazole; Methylmercaptoimidazole; Henning, thiamazol; Thiamazol henning; Hexal, thiamazol; Thiamazol hexal; Methiamazole; Mercaptazole; methimazole; Thiamazolum; Methamazole; Metothyrine; Thymidazole; Danantizol; Merkazolil; Metothyrin; Mercasolyl; Methimazol; Thiamazole; Mercazolyl; USAF el-30; Methymazol; Thymidazol; Strumazol; Mercazole; Thiamazol; Thimazole; Thacapzol; Thimazol; Metazolo; Methizol; Favistan; Thyrozol; Mercazol; Tapazole; Tirodril; Tiamazol; Metizol; Metisol; Thiamazole; Methimazole
数据库引用编号
25 个数据库交叉引用编号
- ChEBI: CHEBI:50673
- KEGG: C07190
- KEGGdrug: D00401
- PubChem: 1349907
- HMDB: HMDB0014901
- Metlin: METLIN1187
- DrugBank: DB00763
- ChEMBL: CHEMBL1515
- Wikipedia: Methimazole
- MeSH: Methimazole
- MetaCyc: CPD-11282
- chemspider: 1131173
- CAS: 223768-14-7
- CAS: 85916-84-3
- CAS: 60-56-0
- MoNA: KO003541
- MoNA: KO003538
- MoNA: KO003540
- MoNA: KO003539
- MoNA: AU116601
- MoNA: KO003537
- PMhub: MS000003454
- PubChem: 9399
- PDB-CCD: MMZ
- RefMet: Methimazole
分类词条
相关代谢途径
Reactome(4)
BioCyc(0)
PlantCyc(0)
代谢反应
50 个相关的代谢反应过程信息。
Reactome(50)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- Phase I - Functionalization of compounds:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- Phase I - Functionalization of compounds:
CH3CHO + H2O + NAD ⟶ CH3COO- + H+ + NADH
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- Phase I - Functionalization of compounds:
CH3CHO + H2O + NAD ⟶ CH3COO- + H+ + NADH
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Biological oxidations:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- Phase I - Functionalization of compounds:
H+ + Oxygen + TPNH + aflatoxin B1 ⟶ AFXBO + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
- Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Biological oxidations:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- Phase I - Functionalization of compounds:
11DCORT + H+ + Oxygen + TPNH ⟶ CORT + H2O + TPN
- FMO oxidises nucleophiles:
H+ + MTZ + Oxygen + TPNH ⟶ H2O + MTZ-SOX + TPN
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- James C Fazioli, Margaret K Mulligan, Erin K Ison, J Alex Pasternak. Impact of methimazole-induced hypothyroidism on postnatal swine.
Physiological reports.
2024 Apr; 12(8):e16007. doi:
10.14814/phy2.16007
. [PMID: 38658325] - Zhenxing Zhang, Min Meng, Qiong Wu, Jeong-Han Kim, Yongzhe Zhu. Biodegradation and metabolic pathway of quinalphos by Cunninghamella elegans ATCC36112.
Biotechnology letters.
2023 May; ?(?):. doi:
10.1007/s10529-023-03393-9
. [PMID: 37195489] - Gaëlle Schils, Ellen De Paepe, Bruno Lapauw, Ellen Vanden Broecke, Laurens Van Mulders, Lynn Vanhaecke, Aurélie Lyssens, Lisa Stammeleer, Sylvie Daminet. Evaluation of potential thiamazole exposure of owners of orally treated hyperthyroid cats.
Journal of feline medicine and surgery.
2022 06; 24(6):e138-e141. doi:
10.1177/1098612x221091738
. [PMID: 35471087] - S Balasurya, Mohammad K Okla, Ibrahim A Alaraidh, Walid Soufan, Abdullah A Al-Ghamdi, Syed R Ahamad, Mostafa A Abdel-Maksoud, Hamada AbdElgawad, Lija L Raju, Ajith M Thomas, S Sudheer Khan. Photodegradation of 5-flurouracil, carvedilol, para-chlorophenol and methimazole with 3D MnWO4 nanoflower modified Ag2WO4 nanorods: A non-genotoxic nanomaterial for water treatment.
Chemosphere.
2022 Jun; 297(?):134130. doi:
10.1016/j.chemosphere.2022.134130
. [PMID: 35257704] - Julio Alvarez Gamero, Victor García Ruiz, Jose Paz Ibarra. Use of unconventional antithyroid therapy in patients with thiamazole agranulocytosis in the context of the COVID-19 pandemic.
Archives of endocrinology and metabolism.
2022 03; 66(1):132-133. doi:
10.20945/2359-3997000000453
. [PMID: 35263055] - Daiki Setoyama, Ho Yeop Lee, Ji Sun Moon, Jingwen Tian, Yea Eun Kang, Ju Hee Lee, Minho Shong, Dongchon Kang, Hyon-Seung Yi. Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease.
Journal of cachexia, sarcopenia and muscle.
2022 02; 13(1):355-367. doi:
10.1002/jcsm.12889
. [PMID: 34970859] - Ichiro Kobayashi, Masaki Shimomura, Masahiro Ueki, Shunichiro Takezaki, Yuka Okura, Mitsuru Nawate, Masafumi Yamada, Yutaka Takahashi, Tadashi Ariga. Development of Graves' disease during drug-free remission of juvenile dermatomyositis.
Modern rheumatology case reports.
2022 Jan; 6(1):55-58. doi:
10.1093/mrcr/rxab006
. [PMID: 34515780] - Louise Ramhøj, Terje Svingen, Caroline Frädrich, Eddy Rijntjes, Eva K Wirth, Katrine Pedersen, Josef Köhrle, Marta Axelstad. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
Toxicology letters.
2022 Jan; 354(?):44-55. doi:
10.1016/j.toxlet.2021.10.010
. [PMID: 34757178] - Mengxue Yang, Xiaodi Zheng, Yueyue Wu, Rui Zhang, Qian Yang, Zhiyan Yu, Jun Liu, Bingbing Zha, Qihai Gong, Bo Yang, Bowen Sun, Miao Zeng. Preliminary Observation of the Changes in the Intestinal Flora of Patients With Graves' Disease Before and After Methimazole Treatment.
Frontiers in cellular and infection microbiology.
2022; 12(?):794711. doi:
10.3389/fcimb.2022.794711
. [PMID: 35402292] - Daniela Gallo, Lorenzo Mortara, Giovanni Veronesi, Simona Am Cattaneo, Angelo Genoni, Matteo Gallazzi, Carlo Peruzzo, Paolo Lasalvia, Paola Moretto, Antonino Bruno, Alberto Passi, Andrea Pini, Andrea Nauti, Maria Antonietta Lavizzari, Michele Marinò, Giulia Lanzolla, Maria Laura Tanda, Luigi Bartalena, Eliana Piantanida. Add-On Effect of Selenium and Vitamin D Combined Supplementation in Early Control of Graves' Disease Hyperthyroidism During Methimazole Treatment.
Frontiers in endocrinology.
2022; 13(?):886451. doi:
10.3389/fendo.2022.886451
. [PMID: 35784564] - Sara Trzos, Paweł Link-Lenczowski, Grzegorz Sokołowski, Ewa Pocheć. Changes of IgG N-Glycosylation in Thyroid Autoimmunity: The Modulatory Effect of Methimazole in Graves' Disease and the Association With the Severity of Inflammation in Hashimoto's Thyroiditis.
Frontiers in immunology.
2022; 13(?):841710. doi:
10.3389/fimmu.2022.841710
. [PMID: 35370997] - Lijing Sun, Liguo Wu, Yaqin An, Minghua Zhang, Bingjie Hou, Hongmei Liu. The effects of levothyroxine combined with methimazole on the clinical efficacy of hyperthyroidism treatment.
Pakistan journal of pharmaceutical sciences.
2022 Jan; 35(1(Special)):369-373. doi:
. [PMID: 35236650]
- Dongchun Zhu, Shiqi Zhang, Xi Cao, Quan Xia, Qiu Zhang, Datong Deng, Shan Gao, Haixia Yu, Yaru Liu, Haiyun Zhou, Fangbiao Tao, Xuqun Sun. Thionamide-induced Agranulocytosis: A Retrospective Analysis of 36 Patients With Hyperthyroidism.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2021 Dec; 27(12):1183-1188. doi:
10.1016/j.eprac.2021.06.017
. [PMID: 34216800] - Toshie Iijima, Teruo Jojima, Soichiro Hosonuma, Eriko Ohhira, Takuya Tomaru, Takahiko Kogai, Isao Usui, Yoshimasa Aso. Symptomatic hypocalcemia after treatment for hyperthyroidism in a woman with chromosome 22q11.2 deletion syndrome complicated by Graves' disease: longitudinal changes in the number of subsets of CD4 and CD8 lymphocytes after thyroidectomy.
Endocrine journal.
2021 Oct; 68(10):1187-1195. doi:
10.1507/endocrj.ej20-0717
. [PMID: 33980771] - Stephanie Allelein, Matthias Schott. [Graves' Disease].
Deutsche medizinische Wochenschrift (1946).
2021 10; 146(20):1337-1343. doi:
10.1055/a-1258-5429
. [PMID: 34644794] - Yoon-Kyung Ji, Shin-Hee Kim. Myopathy Associated with Treatment of Graves' Disease.
Medicina (Kaunas, Lithuania).
2021 Sep; 57(10):. doi:
10.3390/medicina57101016
. [PMID: 34684053] - Jinhui Zeng, Fangtao Luo, Zhihua Lin, Yinghong Chen, Xiaoyun Wang, Yuanhao Song. Rash and cholestatic liver injury caused by methimazole in a woman with Turner syndrome and Graves's disease: a case report and literature review.
BMC endocrine disorders.
2021 Sep; 21(1):179. doi:
10.1186/s12902-021-00819-1
. [PMID: 34479513] - J Chen, W Wang, Z Guo, S Huang, H Lei, P Zang, B Lu, J Shao, P Gu. Associations between gut microbiota and thyroidal function status in Chinese patients with Graves' disease.
Journal of endocrinological investigation.
2021 Sep; 44(9):1913-1926. doi:
10.1007/s40618-021-01507-6
. [PMID: 33481211] - S Khamisi, M Lundqvist, P Emadi, K Almby, Ö Ljunggren, F A Karlsson. Serum thyroglobulin is associated with orbitopathy in Graves' disease.
Journal of endocrinological investigation.
2021 Sep; 44(9):1905-1911. doi:
10.1007/s40618-021-01505-8
. [PMID: 33515213] - Lijuan Sun, Hui Jen Goh, Sanjay Verma, Priya Govindharajulu, Suresh Anand Sadananthan, Navin Michael, Yaligar Jadegoud, Christiani Jeyakumar Henry, S Sendhil Velan, Pei Shan Yeo, Yingshan Lee, Brenda Su Ping Lim, Huiling Liew, Chee Kian Chew, Timothy Peng Lim Quek, Shaikh A K K Abdul Shakoor, Wai Han Hoi, Siew Pang Chan, Daniel Ek Chew, Rinkoo Dalan, Melvin Khee Shing Leow. Metabolic effects of brown fat in transitioning from hyperthyroidism to euthyroidism.
European journal of endocrinology.
2021 Aug; 185(4):553-563. doi:
10.1530/eje-21-0366
. [PMID: 34342595] - Shuang Tan, Long Chen, Likun Jin, Xiaomin Fu. The efficiency and safety of methimazole and propylthiouracil in hyperthyroidism: A meta-analysis of randomized controlled trials.
Medicine.
2021 Jul; 100(30):e26707. doi:
10.1097/md.0000000000026707
. [PMID: 34397700] - Ye Liu, Xing Li, Yikun Zhu, Jiong Liu, Sunjun Liu. Subclinical hypothyroidism contributes to poor glycemic control in patients with type 2 diabetes mellitus, and ellagic acid attenuates methimazole-induced abnormal glucose metabolism in mice model.
Journal of food biochemistry.
2021 06; 45(6):e13753. doi:
10.1111/jfbc.13753
. [PMID: 33955004] - Weihao Shi, Yijun Huang, Zhou Yang, Liang Zhu, Bo Yu. Reduction of TMAO level enhances the stability of carotid atherosclerotic plaque through promoting macrophage M2 polarization and efferocytosis.
Bioscience reports.
2021 05; 41(6):. doi:
10.1042/bsr20204250
. [PMID: 33969376] - Fereidoun Azizi, Atieh Amouzegar, Hengameh Abdi. Efficacy of low-dose methimazole in control of multiple relapses of Graves' hyperthyroidism: a case report.
Journal of medical case reports.
2021 Apr; 15(1):189. doi:
10.1186/s13256-021-02788-4
. [PMID: 33888159] - Yusaku Mori, Munenori Hiromura, Michishige Terasaki, Hideki Kushima, Makoto Ohara, Tomoyasu Fukui, Yasuyoshi Takahashi, Sho-Ichi Yamagishi. Very rare case of Graves' disease with resistance to methimazole: a case report and literature review.
The Journal of international medical research.
2021 Mar; 49(3):300060521996192. doi:
10.1177/0300060521996192
. [PMID: 33682498] - Keiichi Washio, Mizuki Uenaka, Kenji Tanimura, Masashi Deguchi, Kosuke Nishida, Kazumichi Fujioka, Hideto Yamada. Fetal Goitrous Hyperthyroidism in a Pregnant Woman with Triiodothyronine-Predominant Graves' Disease.
The Kobe journal of medical sciences.
2021 Feb; 66(4):E153-E158. doi:
. [PMID: 33994519]
- Fereidoun Azizi, Hengameh Abdi, Atieh Amouzegar. Control of Graves' hyperthyroidism with very long-term methimazole treatment: a clinical trial.
BMC endocrine disorders.
2021 Jan; 21(1):16. doi:
10.1186/s12902-020-00670-w
. [PMID: 33446181] - Cesidio Giuliani, Ines Bucci, Giorgio Napolitano. Phenylmethimazole is a candidate drug for the treatment of severe forms of coronavirus disease 2019 (COVID-19) as well as other virus-induced 'cytokines storm'.
Medical hypotheses.
2021 Jan; 146(?):110473. doi:
10.1016/j.mehy.2020.110473
. [PMID: 33385879] - Jing-E Zhu, Hui-Li Zhang, Song-Yuan Yu, Hui-Xiong Xu. US-guided percutaneous microwave ablation for hyperthyroidism and immediate treatment response evaluation with contrast-enhanced ultrasound.
Clinical hemorheology and microcirculation.
2021; 79(3):435-444. doi:
10.3233/ch-211180
. [PMID: 34092625] - George J Kahaly. Management of Graves Thyroidal and Extrathyroidal Disease: An Update.
The Journal of clinical endocrinology and metabolism.
2020 12; 105(12):. doi:
10.1210/clinem/dgaa646
. [PMID: 32929476] - Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue.
Archives of toxicology.
2020 12; 94(12):4037-4041. doi:
10.1007/s00204-020-02869-1
. [PMID: 32808185] - Fereidoun Azizi. Long-Term Treatment of Hyperthyroidism with Antithyroid Drugs: 35 Years of Personal Clinical Experience.
Thyroid : official journal of the American Thyroid Association.
2020 10; 30(10):1451-1457. doi:
10.1089/thy.2019.0814
. [PMID: 32253999] - M Mateu-Salat, E Urgell, A Chico. SARS-COV-2 as a trigger for autoimmune disease: report of two cases of Graves' disease after COVID-19.
Journal of endocrinological investigation.
2020 Oct; 43(10):1527-1528. doi:
10.1007/s40618-020-01366-7
. [PMID: 32686042] - Chunyan Xie, Chaozhu He, Jun Gao, Shulei Jia. Efficacy and safety of tripterygium glycosides in the treatment of hyperthyroidism: A systemic review and meta-analysis.
Medicine.
2020 Sep; 99(38):e22282. doi:
10.1097/md.0000000000022282
. [PMID: 32957384] - Maorong Wang, Yerong Yu. THERAPEUTIC EFFECTS OF COMBINATION REGIMENS INCLUDING METHIMAZOLE ON GRAVES HYPERTHYROIDISM: A NETWORK META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
2020 Jun; 26(6):675-687. doi:
10.4158/ep-2019-0555
. [PMID: 32160045] - Maribel Méndez-Tepepa, Dafne Zepeda-Pérez, Marlen Espindola-Lozano, Julia Rodríguez-Castelán, Omar Arroyo-Helguera, Pablo Pacheco, Leticia Nicolás-Toledo, Estela Cuevas-Romero. Hypothyroidism modifies differentially the content of lipids and glycogen, lipid receptors, and intraepithelial lymphocytes among oviductal regions of rabbits.
Reproductive biology.
2020 Jun; 20(2):247-253. doi:
10.1016/j.repbio.2020.02.004
. [PMID: 32089504] - Yusuke Ito, Hiroyuki Sakai, Hidenori Nagao, Ryota Suzuki, Masato Odawara, Kouichi Minato. Development of a high-performance liquid chromatography-tandem mass spectrometric method for the determination of Methimazole in human blood matrices.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2020 May; 1144(?):122083. doi:
10.1016/j.jchromb.2020.122083
. [PMID: 32251990] - Baimei Zeng, Ling Yuan, Jun Chu, Yanqing Yang, Shide Lin. Challenges in early identification of causes and treatment of cholestasis in patients with hyperthyroidism: a case report and literature review.
The Journal of international medical research.
2020 Mar; 48(3):300060519891018. doi:
10.1177/0300060519891018
. [PMID: 31840543] - Ahmed Y F Mahmoud, Casey J Rusin, Mark T McDermott. Gold nanostars as a colloidal substrate for in-solution SERS measurements using a handheld Raman spectrometer.
The Analyst.
2020 Feb; 145(4):1396-1407. doi:
10.1039/c9an02439e
. [PMID: 32016204] - Abigail Shell, Joshua W Sullivan. Acute Kidney Injury Following Methimazole Initiation: A Case Report.
Journal of pharmacy practice.
2020 Feb; 33(1):99-101. doi:
10.1177/0897190018789277
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Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
2020 Feb; 128(2):119-124. doi:
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The Journal of international medical research.
2020 Feb; 48(2):300060520903666. doi:
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Brain imaging and behavior.
2020 Feb; 14(1):30-41. doi:
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Toxicological sciences : an official journal of the Society of Toxicology.
2020 02; 173(2):280-292. doi:
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Endocrine journal.
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Medicine.
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Archives of toxicology.
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Drug and chemical toxicology.
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Open veterinary journal.
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Bioscience reports.
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Pediatric nephrology (Berlin, Germany).
2019 08; 34(8):1383-1385. doi:
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Pediatric nephrology (Berlin, Germany).
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La Clinica terapeutica.
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The Journal of clinical endocrinology and metabolism.
2019 07; 104(7):2561-2568. doi:
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Chemical senses.
2019 05; 44(5):327-338. doi:
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Pediatrics.
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Endocrine journal.
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BMC endocrine disorders.
2019 Jan; 19(1):12. doi:
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Current molecular pharmacology.
2019; 12(2):139-146. doi:
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Medicine.
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Pakistan journal of pharmaceutical sciences.
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European journal of endocrinology.
2018 Oct; 179(5):R261-R274. doi:
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Journal of chromatographic science.
2018 Oct; 56(9):858-866. doi:
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Complementary therapies in medicine.
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BMC developmental biology.
2018 06; 18(1):15. doi:
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Journal of separation science.
2018 Mar; 41(5):1083-1090. doi:
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Thyroid : official journal of the American Thyroid Association.
2018 03; 28(3):377-385. doi:
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Bulletin of experimental biology and medicine.
2018 Mar; 164(4):508-513. doi:
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Journal of feline medicine and surgery.
2018 02; 20(2):179-183. doi:
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Molecular and cellular endocrinology.
2017 Dec; 458(?):6-15. doi:
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Pharmaceutical biology.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2017 Oct; 94(?):124-128. doi:
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Thyroid : official journal of the American Thyroid Association.
2017 09; 27(9):1109-1117. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2017 06; 70(?):116-125. doi:
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Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2017 Jun; 196(?):54-60. doi:
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Endocrinology.
2017 04; 158(4):842-851. doi:
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Journal of endocrinological investigation.
2017 Mar; 40(3):281-287. doi:
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Journal of the American Animal Hospital Association.
2017 Mar; 53(2):111-118. doi:
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Neurotoxicology.
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Polish archives of internal medicine.
2017 02; 127(2):131-132. doi:
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Dec; 84(?):1849-1857. doi:
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Oncotarget.
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Scientific reports.
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Thyroid : official journal of the American Thyroid Association.
2016 10; 26(10):1431-1440. doi:
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Toxicology letters.
2016 Sep; 259(?):108-115. doi:
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Toxicology and applied pharmacology.
2016 09; 307(?):1-9. doi:
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Molecular pharmacology.
2016 09; 90(3):265-74. doi:
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Scientific reports.
2016 08; 6(?):31381. doi:
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Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
2016 Jul; 57(4):427-40. doi:
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Endocrine journal.
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Toxicological sciences : an official journal of the Society of Toxicology.
2016 05; 151(1):57-70. doi:
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Journal of applied toxicology : JAT.
2016 May; 36(5):702-15. doi:
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Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.
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Journal of feline medicine and surgery.
2016 Feb; 18(2):92-103. doi:
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Clinical endocrinology.
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International immunopharmacology.
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BMC endocrine disorders.
2015 Nov; 15(?):68. doi:
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Journal of Korean medical science.
2015 Oct; 30(10):1531-4. doi:
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Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
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