3,3'-Dimethylbenzidine (BioDeep_00000002409)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H16N2 (212.1313)
中文名称: 邻联甲苯胺
谱图信息:
最多检出来源 Mus musculus(blood) 13.76%
分子结构信息
SMILES: CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)C)N
InChI: InChI=1S/C14H16N2/c1-9-7-11(3-5-13(9)15)12-4-6-14(16)10(2)8-12/h3-8H,15-16H2,1-2H3
描述信息
CONFIDENCE standard compound; INTERNAL_ID 2434
同义名列表
14 个代谢物同义名
3,3-dimethyl-[1,1-biphenyl]-4,4-diamine; 3,3-Dimethyl-4,4-diaminobiphenyl; 2-Tolidine tetrahydrofluoride; 2-Tolidine hexahydrofluoride; 2-Tolidine perchlorate (1-); 2-Tolidine dihydrofluoride; 2-Tolidine dihydrochloride; 2-Tolidine perchlorate; 3,3`-Dimethylbenzidine; 3,3-dimethylbenzidine; Tolidine blue; o-Tolidine; 2-Tolidine; 3,3'-Dimethylbenzidine
数据库引用编号
18 个数据库交叉引用编号
- ChEBI: CHEBI:34320
- KEGG: C14443
- PubChem: 8413
- HMDB: HMDB0255871
- Metlin: METLIN70065
- ChEMBL: CHEMBL85109
- chemspider: 8106
- CAS: 119-93-7
- MoNA: AU243401
- MoNA: AU243402
- MoNA: AU243405
- MoNA: AU243403
- MoNA: AU243404
- MoNA: AU243406
- PMhub: MS000002539
- PubChem: 17395443
- NIKKAJI: J1.189D
- KNApSAcK: 34320
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- B Shyla, C Vijaya Bhaskar, G Nagendrappa. Iron(III) oxidized nucleophilic coupling of catechol with o-tolidine/p-toluidine followed by 1,10-phenanthroline as new and sensitivity improved spectrophotometric methods for iron present in chemicals, pharmaceutical, edible green leaves, nuts and lake water samples.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2012 Feb; 86(?):152-8. doi:
10.1016/j.saa.2011.09.068. [PMID: 22070994] - Shinpei Kawarai, Kenichi Masuda, Keitaro Ohmori, Shinobu Matsuura, Nobutaka Yasuda, Masahiko Nagata, Masahiro Sakaguchi, Hajime Tsujimoto. Cultivation and characterization of canine skin-derived mast cells.
The Journal of veterinary medical science.
2010 Feb; 72(2):131-40. doi:
10.1292/jvms.09-0281. [PMID: 19940396] - Zhijun Cao, Xueqin Jiang, Wenhua Meng, Qingji Xie, Qin Yang, Ming Ma, Shouzhuo Yao. An EQCM study on the interaction of heparin with the charge-transfer complex generated during o-tolidine electrooxidation: a biosensing mode with a dynamically renewed surface.
Biosensors & bioelectronics.
2007 Oct; 23(3):348-54. doi:
10.1016/j.bios.2007.04.016. [PMID: 17548190] - Patrudu Makena, King-Thom Chung. Evidence that 4-aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species.
Environmental and molecular mutagenesis.
2007 Jun; 48(5):404-13. doi:
10.1002/em.20288. [PMID: 17370336] - Klaus Golka, Silke Kopps, Zdislaw W Myslak. Carcinogenicity of azo colorants: influence of solubility and bioavailability.
Toxicology letters.
2004 Jun; 151(1):203-10. doi:
10.1016/j.toxlet.2003.11.016. [PMID: 15177655] - A K Cook, S D Gilson, W D Fischer, P H Kass. Effect of diet on results obtained by use of two commercial test kits for detection of occult blood in feces of dogs.
American journal of veterinary research.
1992 Oct; 53(10):1749-51. doi:
NULL. [PMID: 1456513] - T G Semak, V P Kurchenko, A T Pikulev. [Status of the antioxidant system and lipid peroxidation in rat liver after poisoning animals with aminobiphenyl].
Biokhimiia (Moscow, Russia).
1991 Oct; 56(10):1806-11. doi:
. [PMID: 1777520] - B M Goldsmith, J M Hicks. Rhabdomyolysis: two pediatric case reports.
Clinical chemistry.
1985 Feb; 31(2):314-7. doi:
. [PMID: 3967373] - H Matsuda, H Tanaka, B L Blas, J S Noseñas, T Tokawa, S Ohsawa. Evaluation of ELISA with ABTS, 2-2'-azino-di-(3-ethylbenzthiazoline sulfonic acid), as the substrate of peroxidase and its application to the diagnosis of schistosomiasis.
The Japanese journal of experimental medicine.
1984 Jun; 54(3):131-8. doi:
. [PMID: 6542945] - K Tanaka, T Mii, S Marui, I Matsubara, H Igaki. Some aspects of metabolism and mutagenicity of o-tolidine and an o-tolidine-based azo dye.
Industrial health.
1982; 20(3):227-35. doi:
10.2486/indhealth.20.227. [PMID: 7174377] - K Tanaka. [Urinary metabolites of o-tolidine (3,3'-dimethylbenzidine) and mutagenicity of the metabolites (author's transl)].
Sangyo igaku. Japanese journal of industrial health.
1981 Mar; 23(2):168-9. doi:
10.1539/joh1959.23.168. [PMID: 7265551] - R K Lynn, D W Donielson, A M Ilias, J M Kennish, K Wong, H B Matthews. Metabolism of bisazobiphenyl dyes derived from benzidine, 3,3'-dimethylbenzidine or 3,3'-dimethoxybenzidine to carcinogenic aromatic amines in the dog and rat.
Toxicology and applied pharmacology.
1980 Nov; 56(2):248-58. doi:
10.1016/0041-008x(80)90296-3. [PMID: 7466824] - H M DIETEREN. METABOLISM OF N,N'-DI(ACETOACETYL)-O-TOLIDINE.
Archives of environmental health.
1964 Aug; 9(?):167-8. doi:
10.1080/00039896.1964.10663815. [PMID: 14155050] - P ENGELBERTZ, E BABEL. [Detection of o-tolidine and of o-dianisidine and their conversion products in urine and in parts of the organs].
Zentralblatt fur Arbeitsmedizin und Arbeitsschutz.
1954 Nov; 4(6):179-83. doi:
NULL. [PMID: 14360520]
