Anisodamine (BioDeep_00000229918)

Main id: BioDeep_00000015616

 

PANOMIX_OTCML-2023


代谢物信息卡片


7(c)micro-hydroxyhyoscyamine;Raceanisodamine; alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Tropic acid 6-hydroxy-3-tropanyl ester

化学式: C17H23NO4 (305.1626998)
中文名称: 消旋山莨菪碱, 山莨菪碱, 阿托品杂质 E
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C2CC(CC1C(C2)O)OC(=O)C(CO)C3=CC=CC=C3
InChI: InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3

描述信息

6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate is a natural product found in Hyoscyamus niger with data available.
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D010276 - Parasympatholytics
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002317 - Cardiovascular Agents > D000889 - Anti-Arrhythmia Agents
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D000975 - Antioxidants > D016166 - Free Radical Scavengers
D020011 - Protective Agents > D000975 - Antioxidants
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
Anisodamine has been investigated for the treatment of Intestinal Diseases.
6-Hydroxyhyoscyamine is a natural product found in Duboisia myoporoides, Anisodus tanguticus, and Hyoscyamus albus with data available.
Anisodamine (6-Hydroxyhyoscyamine), a belladonna alkaloid, is a non-subtype-selective muscarinic, and also a nicotinic cholinoceptor antagonist. Anisodamine employs in traditional Chinese medicine for many ailments, mainly to improve the microcirculation in states of shock, and also in organophosphate poisoning[1][2].
Anisodamine (6-Hydroxyhyoscyamine), a belladonna alkaloid, is a non-subtype-selective muscarinic, and also a nicotinic cholinoceptor antagonist. Anisodamine employs in traditional Chinese medicine for many ailments, mainly to improve the microcirculation in states of shock, and also in organophosphate poisoning[1][2].
Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].
Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].
Racanisodamine is one of the racemic isomers of anisodamine, resembles anisodamine in pharmacological effect. Racanisodamine is a non-selective muscarinic antagonist, used as a component of eye drops for myopic control[1].

同义名列表

36 个代谢物同义名

7(c)micro-hydroxyhyoscyamine;Raceanisodamine; alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Tropic acid 6-hydroxy-3-tropanyl ester; InChI=1/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3; 3-Hydroxy-2-phenyl-propionic acid 6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; (6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate; 6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate; 6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl3-hydroxy-2-phenylpropanoate; WTQYWNWRJNXDEG-UHFFFAOYSA-N; WTQYWNWRJNXDEG-UHFFFAOYSA-; 6-beta-hydroxyhyoscyamine; 7beta-Hydroxyhyoscyamine; anisodamine hydrobromide; 7b-Hydroxyhyoscyamine; 6-Hydroxy hyoscyamine; 6-hydroxyhyoscyamine; Raceanisodamine; Racanisodamine; anisodamine; Benzeneacetic acid, alpha-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (1R-(1-alpha,3-beta(S*),5-alpha,6-alpha))-; BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-, (1R,3S,5R,6S)-6-HYDROXY-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, (.ALPHA.S)-REL-; BENZENEACETIC ACID, .ALPHA.-(HYDROXYMETHYL)-, (1R,3S,5R,6S)-6-HYDROXY-8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER, (.ALPHA.S)-; Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (alphaS)-rel-; Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (alphaS)-; (S)-3-hydroxy-2-phenyl-propionic acid (1r,3s,5r,6S)-6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester, AldrichCPR; [(1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2S)-3-hydroxy-2-phenylpropanoate; [(1S,3S,5S,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; alpha-(Hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester; (-)-6.beta.-hydroxyhyoscyamine; WTQYWNWRJNXDEG-RBZJEDDUSA-N; 6.beta.-Hydroxyhyoscyamine; Raceanisodamine [WHO-DD]; Hyoscyamine, 6-hydroxy-; ANISODAMINE [WHO-DD]; ANISODAMINE [MART.]; Anisodamine, (+/-)-; UNII-U5AC4ZPQ36; U5AC4ZPQ36



数据库引用编号

13 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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WikiPathways(0)

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COVID-19 Disease Map(0)

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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Fei Tang, Dong Liu, Feng Wan, Li Zhang, Li-Yue Xu, Jing-Nan Zhang, Xiao-Lan Zhao, Hui Ao, Cheng Peng. Ameliorative effect of anisodamine (654-1/654-2) against myocardial dysfunction induced by septic shock via the NF-κB/NLRP-3 or the PI3K-AKT/NF-κB pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155277. doi: 10.1016/j.phymed.2023.155277. [PMID: 38128396]
  • Yuan Zhang, Jiayu Zou, Feng Wan, Fu Peng, Cheng Peng. Update on the sources, pharmacokinetics, pharmacological action, and clinical application of anisodamine. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 May; 161(?):114522. doi: 10.1016/j.biopha.2023.114522. [PMID: 37002581]
  • Juan M Minoia, María E Villanueva, Guillermo J Copello, Julián Rodríguez Talou, Alejandra B Cardillo. Recycling of hyoscyamine 6β-hydroxylase for the in vitro production of anisodamine and scopolamine. Applied microbiology and biotechnology. 2023 Apr; ?(?):. doi: 10.1007/s00253-023-12537-w. [PMID: 37099059]
  • Yan Qiu, Zhi Ouyang, Jian Zhong, Junyi Shen, Wenli Jiang, Yan Liu, Feng Wan, Ye Zeng. Anisodamine hydrobromide attenuates oxidative stress and proinflammatory cytokines in septic rats induced by cecal ligation and puncture. Cellular and molecular biology (Noisy-le-Grand, France). 2022 Dec; 68(12):54-60. doi: 10.14715/cmb/2022.68.12.11. [PMID: 37130180]
  • Wei Wei, Ni Kong, Meng-Zhen Liu, Ting Han, Jun-Feng Xu, Chong Liu. Anisodamine potently inhibits SARS-CoV-2 infection in vitro and targets its main protease. Biochemical and biophysical research communications. 2022 08; 616(?):8-13. doi: 10.1016/j.bbrc.2022.05.024. [PMID: 35636257]
  • Yuetian Yu, Cheng Zhu, Yucai Hong, Lin Chen, Zhiping Huang, Jiancang Zhou, Xin Tian, Dadong Liu, Bo Ren, Cao Zhang, Caibao Hu, Xinan Wang, Rui Yin, Yuan Gao, Zhongheng Zhang. Effectiveness of anisodamine for the treatment of critically ill patients with septic shock: a multicentre randomized controlled trial. Critical care (London, England). 2021 09; 25(1):349. doi: 10.1186/s13054-021-03774-4. [PMID: 34579741]
  • Shu Zhang, Xianzhi Xu, Yuanhong Huang, Siyuan Sun, Chengqi Jin, Hao Ji, Dong Sun, Anzhou Xia. Anisodamine ameliorates ischemia/reperfusion-induced renal injury in rats through activation of the extracellular signal-regulated kinase (ERK) pathway and anti-apoptotic effect. Die Pharmazie. 2021 05; 76(5):220-224. doi: 10.1691/ph.2021.1302. [PMID: 33964996]
  • Lingjiang Zeng, Qiaozhuo Zhang, Chunxue Jiang, Yueyue Zheng, Youwei Zuo, Jianbo Qin, Zhihua Liao, Hongping Deng. Development of Atropa belladonna L. Plants with High-Yield Hyoscyamine and without Its Derivatives Using the CRISPR/Cas9 System. International journal of molecular sciences. 2021 Feb; 22(4):. doi: 10.3390/ijms22041731. [PMID: 33572199]
  • Zile Wang, Pimiao Zheng, Jianyi Wang, Shuang He, Zhenhui Ren, Yanfang Zhang, Jincheng Xiong, Haiyang Jiang. Indirect competitive enzyme-linked immunosorbent assay based on a broad-spectrum monoclonal antibody for tropane alkaloids detection in pig urine, pork and cereal flours. Food chemistry. 2021 Feb; 337(?):127617. doi: 10.1016/j.foodchem.2020.127617. [PMID: 32799156]
  • Feng Wan, Xiaoqiang Du, Huan Liu, Xueling He, Ye Zeng. Protective effect of anisodamine hydrobromide on lipopolysaccharide-induced acute kidney injury. Bioscience reports. 2020 07; 40(7):. doi: 10.1042/bsr20201812. [PMID: 32573678]
  • Zhiwei Xu, Tong Wang, Liang Chen, Ying Lou, Xiaoyan Sun, Jinqi Jiang. Treatment of dilated cardiomyopathy caused by coronary microvascular dysfunction with anisodamine: a report of 5 cases. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan. 2020 04; 40(2):340-342. doi: . [PMID: 32242401]
  • Yiyi Yan, Xingchen Huo, Taoshan Ai, Jianguo Su. β-glucan and anisodamine can enhance the immersion immune efficacy of inactivated cyprinid herpesvirus 2 vaccine in Carassius auratus gibelio. Fish & shellfish immunology. 2020 Mar; 98(?):285-295. doi: 10.1016/j.fsi.2020.01.025. [PMID: 31962149]
  • Tengfei Zhao, Siqi Li, Jing Wang, Qi Zhou, Chunxian Yang, Feng Bai, Xiaozhong Lan, Min Chen, Zhihua Liao. Engineering Tropane Alkaloid Production Based on Metabolic Characterization of Ornithine Decarboxylase in Atropa belladonna. ACS synthetic biology. 2020 02; 9(2):437-448. doi: 10.1021/acssynbio.9b00461. [PMID: 31935324]
  • Zhen Qin, Kefa Xiang, Ding-Feng Su, Yang Sun, Xia Liu. Activation of the Cholinergic Anti-Inflammatory Pathway as a Novel Therapeutic Strategy for COVID-19. Frontiers in immunology. 2020; 11(?):595342. doi: 10.3389/fimmu.2020.595342. [PMID: 33633726]
  • Tianxiang Lei, Huan Wang, Songling Li, Xiaojian Cai, Shilong Chen, Tingfeng Cheng, Jianwei Shen, Shengbo Shi, Dangwei Zhou. Comparison of Profiling of Hairy Root of Two Tibetan Medicinal Plants Przewalskia tangutica Maxim. and Anisodus tanguticus Maxim. Current pharmaceutical biotechnology. 2020; 21(6):516-527. doi: 10.2174/1389201020666191127125842. [PMID: 31775597]
  • Yun-Feng Li, Bing-Yuan Xu, Ran An, Xin-Fang Du, Kun Yu, Jia-Hua Sun, Guo-Hong Zhang, Wei Wang, Li-Ping An, Guang-Li Wu. Protective effect of anisodamine in rats with glycerol-induced acute kidney injury. BMC nephrology. 2019 06; 20(1):223. doi: 10.1186/s12882-019-1394-y. [PMID: 31208365]
  • Daniel Schlesinger, Rachel Davidovich Rikanati, Sergei Volis, Adi Faigenboim, Vera Vendramin, Federica Cattonaro, Matthew Hooper, Elad Oren, Mark Taylor, Yaron Sitrit, Moshe Inbar, Efraim Lewinsohn. Alkaloid chemodiversity in Mandragora spp. is associated with loss-of-functionality of MoH6H, a hyoscyamine 6β-hydroxylase gene. Plant science : an international journal of experimental plant biology. 2019 Jun; 283(?):301-310. doi: 10.1016/j.plantsci.2019.03.013. [PMID: 31128700]
  • Jiacheng Zhang, Xiaozhe Fu, Yanqi Zhang, Wentao Zhu, Yong Zhou, Gailing Yuan, Xiaoling Liu, Taoshan Ai, Lingbing Zeng, Jianguo Su. Chitosan and anisodamine improve the immune efficacy of inactivated infectious spleen and kidney necrosis virus vaccine in Siniperca chuatsi. Fish & shellfish immunology. 2019 Jun; 89(?):52-60. doi: 10.1016/j.fsi.2019.03.040. [PMID: 30904683]
  • Kathrin Laura Kohnen, Selahaddin Sezgin, Michael Spiteller, Hansjörg Hagels, Oliver Kayser. Localization and Organization of Scopolamine Biosynthesis in Duboisia myoporoides R. Br. Plant & cell physiology. 2018 Jan; 59(1):107-118. doi: 10.1093/pcp/pcx165. [PMID: 29095998]
  • Xiaopeng Yuan, Yitao Zheng, Chuanbao Chen, Changxi Wang. Anisodamine inhibits endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in rhabdomyolysis-induced acute kidney injury. Apoptosis : an international journal on programmed cell death. 2017 Dec; 22(12):1524-1531. doi: 10.1007/s10495-017-1414-y. [PMID: 28918467]
  • Xiao Li, Wei Qiang, Fei Qiu, Min Chen, Xiao-zhong Lan, Zhi-hua Liao, Xiao-qiang Liu. [Cloning and characterization of an aromatic amino acid aminotransferase(ArAT) gene involved in tropane alkaloid biosynthesis from Hyoscyamus niger]. Yao xue xue bao = Acta pharmaceutica Sinica. 2017 Jan; 52(1):172-9. doi: . [PMID: 29911833]
  • Zhe-Qi Xu, Bo-Zong Shao, Ping Ke, Jian-Guo Liu, Guo-Ku Liu, Xiong-Wen Chen, Ding-Feng Su, Chong Liu. Combined administration of anisodamine and neostigmine rescued acute lethal crush syndrome through α7nAChR-dependent JAK2-STAT3 signaling. Scientific reports. 2016 11; 6(?):37709. doi: 10.1038/srep37709. [PMID: 27874086]
  • Arik Eisenkraft, Avshalom Falk. Possible role for anisodamine in organophosphate poisoning. British journal of pharmacology. 2016 06; 173(11):1719-27. doi: 10.1111/bph.13486. [PMID: 27010563]
  • Yue-De Cao, Yu-Cai He, Hao Li, Guo-Yin Kai, Jian-He Xu, Hui-Lei Yu. Efficient biosynthesis of rare natural product scopolamine using E. coli cells expressing a S14P/K97A mutant of hyoscyamine 6β-hydroxylase AaH6H. Journal of biotechnology. 2015 Oct; 211(?):123-9. doi: 10.1016/j.jbiotec.2015.07.019. [PMID: 26239231]
  • Szymon Dziomba, Teresa Łepek, Zbigniew Jaremicz, Maria Łuczkiewicz, Adam Prahl, Piotr Kowalski. Simultaneous determination of scopolamine, hyoscyamine and anisodamine in in vitro growth media of selected Solanaceae hairy roots by CE method. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Sep; 1001(?):17-21. doi: 10.1016/j.jchromb.2015.06.029. [PMID: 26253806]
  • Fengjie Tian, Cuiyun Li, Xin Wang, Shuangxia Ren, Ning Li, Qi Liu, Sufeng Zhou, Yang Lu, Di Zhao, Xijing Chen. Comparative study on pharmacokinetics of a series of anticholinergics, atropine, anisodamine, anisodine, scopolamine and tiotropium in rats. European journal of drug metabolism and pharmacokinetics. 2015 Sep; 40(3):245-53. doi: 10.1007/s13318-014-0192-y. [PMID: 24748278]
  • Yun-bin Jiang, Yan Gou, Mao-hua Yuan, Yu-ying Ma, Juan Zhou, Pi-e Wu. [HPLC Fingerprint of Anisodus tanguticus Root]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 May; 38(5):957-61. doi: . [PMID: 26767288]
  • Peiting Zhang, Yemeng Li, Guanghui Liu, Xiuman Sun, Yuting Zhou, Xuejiao Deng, Qiongfeng Liao, Zhiyong Xie. Simultaneous determination of atropine, scopolamine, and anisodamine from Hyoscyamus niger L. in rat plasma by high-performance liquid chromatography with tandem mass spectrometry and its application to a pharmacokinetics study. Journal of separation science. 2014 Oct; 37(19):2664-74. doi: 10.1002/jssc.201400534. [PMID: 25044356]
  • Qing-hai You, Dan Zhang, Cheng-cheng Niu, Zhong-ming Zhu, Nan Wang, Yang Yue, Geng-yun Sun. Expression of IL-17A and IL-17F in lipopolysaccharide-induced acute lung injury and the counteraction of anisodamine or methylprednisolone. Cytokine. 2014 Mar; 66(1):78-86. doi: 10.1016/j.cyto.2013.12.019. [PMID: 24548428]
  • Meng Ning, Jing-Hui Huang, Yan-Fang Zhang, Wen-Yu Cui, Hai Wang. [Novel drug composition ameliorating thrombosis and its molecular mechanisms]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. 2014 Mar; 30(2):184-8. doi: . [PMID: 25016879]
  • Xudong Deng, Chong Shen, Qin Meng. Screening of herbal components for attenuating amiodarone-induced hepatotoxicity on gel-entrapped rat hepatocytes. Drug and chemical toxicology. 2014 Jan; 37(1):100-6. doi: 10.3109/01480545.2013.834347. [PMID: 24274456]
  • Chong-Hui Li, Xuan Zhang, Xin-Lan Ge, Xin Huang, Ai-Qun Zhang, Wan-Qing Gu. Effects of combined anisodamine and neostigmine treatment on the inflammatory response and liver regeneration of obstructive jaundice rats after hepatectomy. BioMed research international. 2014; 2014(?):362024. doi: 10.1155/2014/362024. [PMID: 25478569]
  • Zbigniew Jaremicz, Maria Luczkiewicz, Mariusz Kisiel, Rafael Zárate, Nabil El Jaber-Vazdekis, Piotr Migas. Multi-development-HPTLC method for quantitation of hyoscyamine, scopolamine and their biosynthetic precursors in selected solanaceae plants grown in natural conditions and as in vitro cultures. Phytochemical analysis : PCA. 2014 Jan; 25(1):29-35. doi: 10.1002/pca.2455. [PMID: 23839972]
  • Wen Peng Guo, Zhi Bin Rong, Ying Hong Li, Ying Sing Fung, Guo Quan Gao, Zhi Ming Cai. Microfluidic chip capillary electrophoresis coupled with electrochemiluminescence for enantioseparation of racemic drugs using central composite design optimization. Electrophoresis. 2013 Nov; 34(20-21):2962-9. doi: 10.1002/elps.201300238. [PMID: 24037989]
  • Wenxue Li, Jun Wen, Jingyu He, Di Cao, Fanlu Sun, Jinying Li, Guorong Fan. Development and validation of a rapid and sensitive assay for the determination of anisodamine in 50 μL of beagle dog plasma by LC-MS/MS. Journal of separation science. 2013 Oct; 36(19):3184-90. doi: 10.1002/jssc.201300451. [PMID: 23897549]
  • Nengsheng Ye, Jian Li, Chong Gao, Yali Xie. Simultaneous determination of atropine, scopolamine, and anisodamine in Flos daturae by capillary electrophoresis using a capillary coated by graphene oxide. Journal of separation science. 2013 Aug; 36(16):2698-702. doi: 10.1002/jssc.201300304. [PMID: 23868645]
  • Ya-hua Liu, Jie Zhang, Zheng Dai, Man-hong Zhou, Yu-hua Li, Xue-lian Yin, Wei Zhang, Hong Shen. [Protection of anisodamine on the mitochondrial injury induced by oxidative stress in swine with cardiac arrest]. Zhonghua wei zhong bing ji jiu yi xue. 2013 May; 25(5):290-3. doi: 10.3760/cma.j.issn.2095-4352.2013.05.013. [PMID: 23663580]
  • Ya-hua Liu, Man-hong Zhou, Zheng Dai, Jie Zhang, Hai-yan Zhu, Yu-hua Li, Xue-lian Yin, Wei Zhang, Hong Shen. [Protective effect of anisodamine against myocardial cell apoptosis through mitochondria impairment in cardiac arrest in pigs]. Zhonghua wei zhong bing ji jiu yi xue. 2013 Feb; 25(2):88-91. doi: 10.3760/cma.j.issn.2095-4352.2013.02.009. [PMID: 23648158]
  • Wei Geng, Xiang-Hua Fu, Xin-Shun Gu, Yan-Bo Wang, Xue-Chao Wang, Wei Li, Yun-Fa Jiang, Guo-Zhen Hao, Wei-Ze Fan, Ling Xue. Preventive effects of anisodamine against contrast-induced nephropathy in type 2 diabetics with renal insufficiency undergoing coronary angiography or angioplasty. Chinese medical journal. 2012 Oct; 125(19):3368-72. doi: . [PMID: 23044290]
  • Li Sun, Gu-fang Zhang, Xin Zhang, Qing Liu, Jian-guo Liu, Ding-feng Su, Chong Liu. Combined administration of anisodamine and neostigmine produces anti-shock effects: involvement of α7 nicotinic acetylcholine receptors. Acta pharmacologica Sinica. 2012 Jun; 33(6):761-6. doi: 10.1038/aps.2012.26. [PMID: 22580739]
  • Hui Wu, Zhefeng Fan. Mn-doped ZnS quantum dots for the room-temperature phosphorescence detection of raceanisodamine hydrochloride and atropine sulfate in biological fluids. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2012 May; 90(?):131-4. doi: 10.1016/j.saa.2012.01.041. [PMID: 22336044]
  • Yan-bo Wang, Xiang-hua Fu, Xin-shun Gu, Xue-chao Wang, Yu-jun Zhao, Guo-zhen Hao, Yun-fa Jiang, Wei-ze Fan, Wei-li Wu, Shi-qiang Li, Ling Xue. Safety and efficacy of anisodamine on prevention of contrast induced nephropathy in patients with acute coronary syndrome. Chinese medical journal. 2012 Mar; 125(6):1063-7. doi: NULL. [PMID: 22613532]
  • Yanbo Wang, Xianghua Fu, Xuechao Wang, Xinwei Jia, Xinshun Gu, Jing Zhang, Jianling Su, Guozhen Hao, Yunfa Jiang, Weize Fan, Weili Wu, Shiqiang Li. Protective effects of anisodamine on renal function in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The Tohoku journal of experimental medicine. 2011 06; 224(2):91-7. doi: 10.1620/tjem.224.91. [PMID: 21597242]
  • Alejandra Beatriz Cardillo, Angela María Otalvaro Alvarez, Ariel Calabró Lopez, Mario Enrique Velásquez Lozano, Julián Rodríguez Talou, Ana María Giulietti. Anisodamine production from natural sources: seedlings and hairy root cultures of Argentinean and Colombian Brugmansia candida plants. Planta medica. 2010 Mar; 76(4):402-5. doi: 10.1055/s-0029-1186164. [PMID: 19790035]
  • Baiqing Yuan, Chunying Zheng, Hong Teng, Tianyan You. Simultaneous determination of atropine, anisodamine, and scopolamine in plant extract by nonaqueous capillary electrophoresis coupled with electrochemiluminescence and electrochemistry dual detection. Journal of chromatography. A. 2010 Jan; 1217(1):171-4. doi: 10.1016/j.chroma.2009.11.008. [PMID: 19931863]
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