Dehydroabietic acid (BioDeep_00000229910)

 

Secondary id: BioDeep_00000003799

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


InChI=1/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s

化学式: C20H28O2 (300.2089188)
中文名称: 脱氢枞酸, 脱氢松香酸
谱图信息: 最多检出来源 Viridiplantae(plant) 0.79%

分子结构信息

SMILES: c1c2c(cc(c1)C(C)C)CC[C@@H]1[C@@]2(CCC[C@@]1(C)C(=O)O)C
InChI: InChI=1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1

描述信息

Dehydroabietic acid is an abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group. It has a role as a metabolite and an allergen. It is an abietane diterpenoid, a monocarboxylic acid and a carbotricyclic compound. It is functionally related to an abietic acid. It is a conjugate acid of a dehydroabietate.
Dehydroabietic acid is a natural product found in Nostoc, Relhania corymbosa, and other organisms with data available.
Dehydroabietic acid belongs to the class of organic compounds known as diterpenoids. These are terpene compounds formed by four isoprene units.
An abietane diterpenoid that is abieta-8,11,13-triene substituted at position 18 by a carboxy group.
Dehydroabietic acid possesses antiviral activity[1].
Dehydroabietic acid possesses antiviral activity[1].

同义名列表

38 个代谢物同义名

InChI=1/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s; 1-Phenanthrenecarboxylic acid,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1.alpha.,4a.beta.,10a.alpha.)]-; 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R-(1alpha,4abeta,10aalpha))-; (1R-(1ALPHA,4ABETA,10AALPHA))-1,2,3,4,4A,9,10,10A-OCTAHYDRO- 7-ISOPROPYL-1,4A-DIMETHYLPHENANTHREN-1-CARBOXYLIC ACID; (1R-(1alpha,4Abeta,10aalpha))-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylic acid; 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, [1R-(1,4a,10a)]-; 1-PHENANTHRENECARBOXYLIC ACID, 1,2,3,4,4A,9,10,10A- OCTAHYDRO-1,4A-DIMETHYL-7-(1-METHYLETHYL)-, (1R,4AS,10AR)-; 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-; 1-Phenanthrenecarboxylicacid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-,(1R,4aS,10aR)-; (1R,4aS,10aR)-1,4a-dimethyl-7-(propan-2-yl)-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid; rel-(1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid; rel-(1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylicacid; 1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid; 1,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylic acid; 1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenecarboxylate; 5-Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-; Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-; 13-Isopropylpodocarpa-8,11,13-trien-15-oic acid; Podocarpa-8,13-trien-15-oic acid, 13-isopropyl-; Isopropyl podocarpa-8,11,13-trien-15-oic acid; 4-09-00-02389 (Beilstein Handbook Reference); 13-Isopropylpodocarpa-8,13-trien-15-oic acid; 13-Isopropylpodocarpa-8,11,13-trien-15-Oate; Dehydroabietic acid, >=95\\% (LC/MS-ELSD); abieta-8(14),9(11),12-trien-18-oic acid; (+)-Dehydroabietic acid, tech grade; Abieta-8,11,13-trien-18-oic acid; Abieta-8,13-trien-18-oic acid; Abieta-8,11,13-trien-18-Oate; NFWKVWVWBFBAOV-MISYRCLQSA-N; (+)-Dehydroabietic acid; (-)-Dehydroabietic acid; Abietic acid, dehydro-; (-)-Dehydroabietate; Dehydroabietic acid; UNII-0S5XP6S3AU; Dehydroabietate; 0S5XP6S3AU



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

61 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Santiago Michavila Puente-Villegas, Luis Apaza Ticona, Ángel Rumbero Sánchez, José-Luis Acebes. Diterpenes of Pinus pinaster aiton with anti-inflammatory, analgesic, and antibacterial activities. Journal of ethnopharmacology. 2023 Aug; ?(?):117021. doi: 10.1016/j.jep.2023.117021. [PMID: 37567424]
  • Yifeng Zhang, Jie Gao, Lin Ma, Lichan Tu, Tianyuan Hu, Xiaoyi Wu, Ping Su, Yujun Zhao, Yuan Liu, Dan Li, Jiawei Zhou, Yan Yin, Yuru Tong, Huan Zhao, Yun Lu, Jiadian Wang, Wei Gao, Luqi Huang. Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae. Nature communications. 2023 02; 14(1):875. doi: 10.1038/s41467-023-36353-y. [PMID: 36797237]
  • Puying Qi, Na Wang, Taihong Zhang, Yumei Feng, Xiang Zhou, Dan Zeng, Jiao Meng, Liwei Liu, Linhong Jin, Song Yang. Anti-Virulence Strategy of Novel Dehydroabietic Acid Derivatives: Design, Synthesis, and Antibacterial Evaluation. International journal of molecular sciences. 2023 Feb; 24(3):. doi: 10.3390/ijms24032897. [PMID: 36769220]
  • Meng Hao, Jianwei Xu, Houpeng Wen, Jiawei Du, Shaoyong Zhang, Min Lv, Hui Xu. Recent Advances on Biological Activities and Structural Modifications of Dehydroabietic Acid. Toxins. 2022 09; 14(9):. doi: 10.3390/toxins14090632. [PMID: 36136570]
  • Junjie Zhang, Ming Zhang, Yuxuan Dong, Wanting Gu, Tong Liu, Xinwei Xing, Jie Song, Maogong Wang, Chunrui Han. Molecular Design, Supramolecular Assembly, and Excellent Dye Adsorption Capacity of Natural Rigid Dehydroabietic Acid-Tailored Amide Organogelators. Langmuir : the ACS journal of surfaces and colloids. 2022 07; 38(29):8918-8927. doi: 10.1021/acs.langmuir.2c01068. [PMID: 35819938]
  • Nguyen Duy Phan, Ashraf M Omar, Sijia Sun, Juthamart Maneenet, Dya Fita Dibwe, Mao Sato, Surya Kant Kalauni, Naoki Toyooka, Tsutomu Fujii, Suresh Awale. Abietane diterpenes from Abies spectabilis and their anti-pancreatic cancer activity against the MIA PaCa-2 cell line. Bioorganic & medicinal chemistry letters. 2022 06; 66(?):128723. doi: 10.1016/j.bmcl.2022.128723. [PMID: 35395369]
  • Jiadian Wang, Ping Su, Linhui Gao, Yifeng Zhang, Jian Wang, Lichan Tu, Yujun Zhao, Yun Lu, Yan Yin, Luqi Huang, Wei Gao. A cytochrome P450 CYP81AM1 from Tripterygium wilfordii catalyses the C-15 hydroxylation of dehydroabietic acid. Planta. 2021 Oct; 254(5):95. doi: 10.1007/s00425-021-03743-9. [PMID: 34643823]
  • Gai Gao, Zhishen Xie, Er-Wen Li, Yong Yuan, Yu Fu, Pan Wang, Xiaowei Zhang, Yonghui Qiao, Jiangyan Xu, Christian Hölscher, Hui Wang, Zhenqiang Zhang. Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis. Journal of natural medicines. 2021 Jun; 75(3):540-552. doi: 10.1007/s11418-021-01491-4. [PMID: 33590347]
  • Bao-Li Fei, Chun-Nuan Hui, Zuzhuang Wei, Ling-Yan Kong, Jian-Ying Long, Chunhua Qiao, Zhen-Feng Chen. Copper(II) and iron(III) complexes of chiral dehydroabietic acid derived from natural rosin: metal effect on structure and cytotoxicity. Metallomics : integrated biometal science. 2021 04; 13(4):. doi: 10.1093/mtomcs/mfab014. [PMID: 33765148]
  • Lin-Ying Li, Bao-Li Fei, Pingping Wang, Ling-Yan Kong, Jian-Ying Long. Discovery of novel dehydroabietic acid derivatives as DNA/BSA binding and anticancer agents. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Feb; 246(?):118944. doi: 10.1016/j.saa.2020.118944. [PMID: 33007643]
  • Rosario Schicchi, Anna Geraci, Sergio Rosselli, Alberto Spinella, Antonella Maggio, Maurizio Bruno. Phytochemical investigation of the needles of Abies nebrodensis (Lojac.) Mattei. Natural product research. 2020 Aug; 34(15):2131-2136. doi: 10.1080/14786419.2019.1576044. [PMID: 30873863]
  • Zhishen Xie, Gai Gao, Hui Wang, Erwen Li, Yong Yuan, Jiangyan Xu, Zhenqiang Zhang, Pan Wang, Yu Fu, Huahui Zeng, Junying Song, Christian Hölscher, Hui Chen. Dehydroabietic acid alleviates high fat diet-induced insulin resistance and hepatic steatosis through dual activation of PPAR-γ and PPAR-α. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2020 Jul; 127(?):110155. doi: 10.1016/j.biopha.2020.110155. [PMID: 32413669]
  • Reina Omura, Junko Sowa-Osako, Chiharu Tateishi, Ayaka Okazaki, Kazuyoshi Fukai, Tsuyoshi Kawakami, Maiko Tahara, Daisuke Tsuruta. Allergic contact dermatitis to abietic acid derivatives in an over-the-counter hydrocolloid dressing. Contact dermatitis. 2020 May; 82(5):309-310. doi: 10.1111/cod.13461. [PMID: 31891190]
  • Lichan Tu, Ping Su, Zhongren Zhang, Linhui Gao, Jiadian Wang, Tianyuan Hu, Jiawei Zhou, Yifeng Zhang, Yujun Zhao, Yuan Liu, Yadi Song, Yuru Tong, Yun Lu, Jian Yang, Cao Xu, Meirong Jia, Reuben J Peters, Luqi Huang, Wei Gao. Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis. Nature communications. 2020 02; 11(1):971. doi: 10.1038/s41467-020-14776-1. [PMID: 32080175]
  • Natalia A Luchnikova, Kseniya M Ivanova, Ekaterina V Tarasova, Victoria V Grishko, Irina B Ivshina. Microbial Conversion of Toxic Resin Acids. Molecules (Basel, Switzerland). 2019 Nov; 24(22):. doi: 10.3390/molecules24224121. [PMID: 31739575]
  • Kostas Ioannidis, Eleni Melliou, Prokopios Magiatis. High-Throughput 1H-Nuclear Magnetic Resonance-Based Screening for the Identification and Quantification of Heartwood Diterpenic Acids in Four Black Pine (Pinus nigra Arn.) Marginal Provenances in Greece. Molecules (Basel, Switzerland). 2019 Oct; 24(19):. doi: 10.3390/molecules24193603. [PMID: 31591296]
  • Danping Wang, Lin Feng, Binglei Song, Xiaomei Pei, Zhenggang Cui, Danhua Xie. Viscoelastic lyotropic liquid crystals formed in a bio-based trimeric surfactant system. Soft matter. 2019 May; 15(20):4208-4214. doi: 10.1039/c8sm02594k. [PMID: 31073550]
  • Joséphine Ottavioli, Mathieu Paoli, Joseph Casanova, Félix Tomi, Ange Bighelli. Identification and Quantitative Determination of Resin Acids from Corsican Pinus pinaster Aiton Oleoresin Using 13 C-NMR Spectroscopy. Chemistry & biodiversity. 2019 Jan; 16(1):e1800482. doi: 10.1002/cbdv.201800482. [PMID: 30632681]
  • Zuzana Burčová, František Kreps, Mária Greifová, Michal Jablonský, Aleš Ház, Štefan Schmidt, Igor Šurina. Antibacterial and antifungal activity of phytosterols and methyl dehydroabietate of Norway spruce bark extracts. Journal of biotechnology. 2018 Sep; 282(?):18-24. doi: 10.1016/j.jbiotec.2018.06.340. [PMID: 29940188]
  • Manoela Daiele Gonçalves, B T S Bortoleti, Fernanda Tomiotto-Pellissier, Milena Menegazzo Miranda-Sapla, João Paulo Assolini, Amanda Cristina Machado Carloto, P G C Carvalho, Ellen Takasse Tudisco, Alexandre Urbano, Sérgio Ricardo Ambrósio, Elisa Yoko Hirooka, Andréa Name Colado Simão, Idessania Nazareth Costa, Wander Rogério Pavanelli, Ivete Conchon-Costa, Nilton Syogo Arakawa. Dehydroabietic acid isolated from Pinus elliottii exerts in vitro antileishmanial action by pro-oxidant effect, inducing ROS production in promastigote and downregulating Nrf2/ferritin expression in amastigote forms of Leishmania amazonensis. Fitoterapia. 2018 Jul; 128(?):224-232. doi: 10.1016/j.fitote.2018.05.027. [PMID: 29802873]
  • Wen-Ming Zhang, Yang Yao, Teng Yang, Xue-Ying Wang, Zhen-Yun Zhu, Wen-Tao Xu, Hai-Xia Lin, Zhao-Bing Gao, Hu Zhou, Cai-Guang Yang, Yong-Mei Cui. The synthesis and antistaphylococcal activity of N-sulfonaminoethyloxime derivatives of dehydroabietic acid. Bioorganic & medicinal chemistry letters. 2018 06; 28(10):1943-1948. doi: 10.1016/j.bmcl.2018.03.062. [PMID: 29650291]
  • Malin Silverå Ejneby, Xiongyu Wu, Nina E Ottosson, E Peter Münger, Ingemar Lundström, Peter Konradsson, Fredrik Elinder. Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid. The Journal of general physiology. 2018 05; 150(5):731-750. doi: 10.1085/jgp.201711965. [PMID: 29626041]
  • Jun-Bo Gao, Shuang-Jing Yang, Zi-Ru Yan, Xing-Jie Zhang, De-Bing Pu, Li-Xia Wang, Xiao-Li Li, Rui-Han Zhang, Wei-Lie Xiao. Isolation, Characterization, and Structure-Activity Relationship Analysis of Abietane Diterpenoids from Callicarpa bodinieri as Spleen Tyrosine Kinase Inhibitors. Journal of natural products. 2018 04; 81(4):998-1006. doi: 10.1021/acs.jnatprod.7b01082. [PMID: 29578342]
  • Hiroki Yoshioka, Yuki Mizuno, Tomohiro Yamaguchi, Yoshimi Ichimaru, Koichi Takeya, Yukio Hitotsuyanagi, Tsunemasa Nonogaki, Yutaka Aoyagi. Methyl dehydroabietate counters high fat diet-induced insulin resistance and hepatic steatosis by modulating peroxisome proliferator-activated receptor signaling in mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2018 Mar; 99(?):214-219. doi: 10.1016/j.biopha.2018.01.064. [PMID: 29334664]
  • Hyun-Woo Oh, Chan-Seok Yun, Jun Hyoung Jeon, Ji-Ae Kim, Doo-Sang Park, Hyung Won Ryu, Sei-Ryang Oh, Hyuk-Hwan Song, Yunhee Shin, Chan Sik Jung, Sang Woon Shin. Conifer Diterpene Resin Acids Disrupt Juvenile Hormone-Mediated Endocrine Regulation in the Indian Meal Moth Plodia interpunctella. Journal of chemical ecology. 2017 Jul; 43(7):703-711. doi: 10.1007/s10886-017-0861-9. [PMID: 28674826]
  • Victor Forman, Roberta Callari, Christophe Folly, Harald Heider, Björn Hamberger. Production of Putative Diterpene Carboxylic Acid Intermediates of Triptolide in Yeast. Molecules (Basel, Switzerland). 2017 Jun; 22(6):. doi: 10.3390/molecules22060981. [PMID: 28608823]
  • Fahimeh Moradi-Afrapoli, Samad Nejad Ebrahimi, Martin Smiesko, Matthias Hamburger. HPLC-Based Activity Profiling for GABAA Receptor Modulators in Extracts: Validation of an Approach Utilizing a Larval Zebrafish Locomotor Assay. Journal of natural products. 2017 05; 80(5):1548-1557. doi: 10.1021/acs.jnatprod.7b00081. [PMID: 28485933]
  • Vivien Jagalski, Robert Barker, Daniel Topgaard, Thomas Günther-Pomorski, Björn Hamberger, Marité Cárdenas. Biophysical study of resin acid effects on phospholipid membrane structure and properties. Biochimica et biophysica acta. 2016 11; 1858(11):2827-2838. doi: 10.1016/j.bbamem.2016.08.008. [PMID: 27544924]
  • Maria Sofia Costa, Adriana Rego, Vitor Ramos, Tiago B Afonso, Sara Freitas, Marco Preto, Viviana Lopes, Vitor Vasconcelos, Catarina Magalhães, Pedro N Leão. The conifer biomarkers dehydroabietic and abietic acids are widespread in Cyanobacteria. Scientific reports. 2016 Mar; 6(?):23436. doi: 10.1038/srep23436. [PMID: 26996104]
  • Chung Sub Kim, Lalita Subedi, Sun Yeou Kim, Sang Un Choi, Ki Hyun Kim, Kang Ro Lee. Diterpenes from the Trunk of Abies holophylla and Their Potential Neuroprotective and Anti-inflammatory Activities. Journal of natural products. 2016 Feb; 79(2):387-94. doi: 10.1021/acs.jnatprod.5b01053. [PMID: 26812172]
  • Dongjun Luo, Qing Ni, Anlai Ji, Wen Gu, Junhua Wu, Chunping Jiang. Dehydroabietic Acid Derivative QC4 Induces Gastric Cancer Cell Death via Oncosis and Apoptosis. BioMed research international. 2016; 2016(?):2581061. doi: 10.1155/2016/2581061. [PMID: 27057539]
  • Abir Nachar, Ammar Saleem, John T Arnason, Pierre S Haddad. Regulation of liver cell glucose homeostasis by dehydroabietic acid, abietic acid and squalene isolated from balsam fir (Abies balsamea (L.) Mill.) a plant of the Eastern James Bay Cree traditional pharmacopeia. Phytochemistry. 2015 Sep; 117(?):373-379. doi: 10.1016/j.phytochem.2015.07.001. [PMID: 26164238]
  • Hui Wang, Thi Thanh Hien Nguyen, Shujun Li, Tao Liang, Yuanyuan Zhang, Jian Li. Quantitative structure-activity relationship of antifungal activity of rosin derivatives. Bioorganic & medicinal chemistry letters. 2015 Jan; 25(2):347-54. doi: 10.1016/j.bmcl.2014.11.034. [PMID: 25466709]
  • Won Bum Huh, Jong-Eun Kim, Young-Gyu Kang, Gaeun Park, Tae-gyu Lim, Jung Yeon Kwon, Da Som Song, Eun Hee Jeong, Charles C Lee, Joe Eun Son, Sang Gwon Seo, Eunjung Lee, Jong Rhan Kim, Chang Yong Lee, Jun Seong Park, Ki Won Lee. Brown Pine Leaf Extract and Its Active Component Trans-Communic Acid Inhibit UVB-Induced MMP-1 Expression by Targeting PI3K. PloS one. 2015; 10(6):e0128365. doi: 10.1371/journal.pone.0128365. [PMID: 26066652]
  • Sandro Donizete Caetano da Silva, Maria Gorete Mendes de Souza, Miguel Jorge Oliveira Cardoso, Thais da Silva Moraes, Sérgio Ricardo Ambrósio, Rodrigo Cássio Sola Veneziani, Carlos Henrique G Martins. Antibacterial activity of Pinus elliottii against anaerobic bacteria present in primary endodontic infections. Anaerobe. 2014 Dec; 30(?):146-52. doi: 10.1016/j.anaerobe.2014.09.013. [PMID: 25270831]
  • Luís Fernando Leandro, Miguel Jorge Oliveira Cardoso, Sandro Donizeti Caetano Silva, Maria Gorete Mendes Souza, Rodrigo Cassio Sola Veneziani, Sergio Ricardo Ambrosio, Carlos Henrique Gomes Martins. Antibacterial activity of Pinus elliottii and its major compound, dehydroabietic acid, against multidrug-resistant strains. Journal of medical microbiology. 2014 Dec; 63(Pt 12):1649-1653. doi: 10.1099/jmm.0.081711-0. [PMID: 25261060]
  • Wenyan Gao, Xiaoyan Dong, Nan Xie, Chunlan Zhou, Yuhua Fan, Guoyou Chen, Yanming Wang, Taiming Wei, Daling Zhu. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules (Basel, Switzerland). 2014 Jun; 19(6):8503-17. doi: 10.3390/molecules19068503. [PMID: 24959678]
  • Z Pandelides, J Guchardi, D Holdway. Dehydroabietic acid (DHAA) alters metabolic enzyme activity and the effects of 17β-estradiol in rainbow trout (Oncorhynchus mykiss). Ecotoxicology and environmental safety. 2014 Mar; 101(?):168-76. doi: 10.1016/j.ecoenv.2013.11.027. [PMID: 24507142]
  • Guang Zhang, Chunping Jiang, Zhongxia Wang, Weibo Chen, Wen Gu, Yitao Ding. Dehydroabietic acid derivative QC2 induces oncosis in hepatocellular carcinoma cells. BioMed research international. 2014; 2014(?):682197. doi: 10.1155/2014/682197. [PMID: 25110686]
  • Yanhong Xing, Wei Zhang, Jingjing Song, Yixin Zhang, Xianxing Jiang, Rui Wang. Anticancer effects of a novel class rosin-derivatives with different mechanisms. Bioorganic & medicinal chemistry letters. 2013 Jul; 23(13):3868-72. doi: 10.1016/j.bmcl.2013.04.069. [PMID: 23707051]
  • Ken-ichi Kimura, Yuki Minamikawa, Yukiko Ogasawara, Jun Yoshida, Kei-ichi Saitoh, Hisao Shinden, Yue Qi Ye, Shunya Takahashi, Tokichi Miyakawa, Hiroyuki Koshino. Kujigamberol, a new dinorlabdane diterpenoid isolated from 85million years old Kuji amber using a biotechnological assay. Fitoterapia. 2012 Jul; 83(5):907-12. doi: 10.1016/j.fitote.2012.03.024. [PMID: 22507387]
  • Wen Chen, Sheng'an Tang, Nan Qin, Huiyuan Zhai, Hongquan Duan. [Antioxidant constituents from Smilax riparia]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Mar; 37(6):806-10. doi: . [PMID: 22715727]
  • Suvi T Häkkinen, Petri Lackman, Heli Nygrén, Kirsi-Marja Oksman-Caldentey, Hannu Maaheimo, Heiko Rischer. Differential patterns of dehydroabietic acid biotransformation by Nicotiana tabacum and Catharanthus roseus cells. Journal of biotechnology. 2012 Jan; 157(2):287-94. doi: 10.1016/j.jbiotec.2011.11.008. [PMID: 22178236]
  • Axel Schmidt, Raimund Nagel, Trygve Krekling, Erik Christiansen, Jonathan Gershenzon, Paal Krokene. Induction of isoprenyl diphosphate synthases, plant hormones and defense signalling genes correlates with traumatic resin duct formation in Norway spruce (Picea abies). Plant molecular biology. 2011 Dec; 77(6):577-90. doi: 10.1007/s11103-011-9832-7. [PMID: 22002747]
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