sn-Glycero-3-phosphocholine (BioDeep_00000229618)
Main id: BioDeep_00000003455
human metabolite
代谢物信息卡片
2-(((R)-2,3-Dihydroxypropyl)phosphoryloxy)-N,N,N-trimethylethanaminium
化学式: [C8H21NO6P]+ (258.1106)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+](C)(C)CCOP(=O)(O)OCC(CO)O
InChI: InChI=1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/p+1/t8-/m1/s1
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:194386
- KEGG: C00670
- PubChem: 439285
- HMDB: HMDB00086
- MoNA: MT000125
- ChEBI: CHEBI:16870
- PubChem: 3939
- CAS: 28319-77-9
- PDB-CCD: CH5
- 3DMET: B01306
- NIKKAJI: J247.898F
- RefMet: sn-Glycero-3-phosphocholine
- KNApSAcK: 16870
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Takashi Kawamura, Takeshi Okubo, Koji Sato, Satoshi Fujita, Kazushige Goto, Takafumi Hamaoka, Motoyuki Iemitsu. Glycerophosphocholine enhances growth hormone secretion and fat oxidation in young adults.
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The open microbiology journal.
2009 Aug; 3(?):136-45. doi:
10.2174/1874285800903010136. [PMID: 19707290] - Jasmina Saric, Jia V Li, Yulan Wang, Jennifer Keiser, Kirill Veselkov, Stephan Dirnhofer, Ivan K S Yap, Jeremy K Nicholson, Elaine Holmes, Jürg Utzinger. Panorganismal metabolic response modeling of an experimental Echinostoma caproni infection in the mouse.
Journal of proteome research.
2009 Aug; 8(8):3899-911. doi:
10.1021/pr900185s. [PMID: 19489577] - Morgan Gallazzini, Maurice B Burg. What's new about osmotic regulation of glycerophosphocholine.
Physiology (Bethesda, Md.).
2009 Aug; 24(?):245-9. doi:
10.1152/physiol.00009.2009. [PMID: 19675355] - Iola F Duarte, Joana Marques, Ana F Ladeirinha, Cláudia Rocha, Inês Lamego, Rita Calheiros, Tânia M Silva, M Paula M Marques, Joana B Melo, Isabel M Carreira, Ana M Gil. Analytical approaches toward successful human cell metabolome studies by NMR spectroscopy.
Analytical chemistry.
2009 Jun; 81(12):5023-32. doi:
10.1021/ac900545q. [PMID: 19462963] - Qinghua He, Xiangfeng Kong, Guoyao Wu, Pingping Ren, Huiru Tang, Fuhua Hao, Ruilin Huang, Tiejun Li, Bie Tan, Peng Li, Zhiru Tang, Yulong Yin, Yongning Wu. Metabolomic analysis of the response of growing pigs to dietary L-arginine supplementation.
Amino acids.
2009 May; 37(1):199-208. doi:
10.1007/s00726-008-0192-9. [PMID: 18989615] - Chan Woo Lee, Mi-Jin Lim, Dongwook Son, Jin-Soo Lee, Moon-Hyun Cheong, In Shu Park, Myoung-Kwan Lim, Eunsil Kim, Yoon Ha. A case of cerebral gumma presenting as brain tumor in a human immunodeficiency virus (HIV)-negative patient.
Yonsei medical journal.
2009 Apr; 50(2):284-8. doi:
10.3349/ymj.2009.50.2.284. [PMID: 19430565] - Jingjing Xu, Jun Zhang, Shuhui Cai, Jiyang Dong, James Y Yang, Zhong Chen. Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1H NMR spectroscopy.
Analytical and bioanalytical chemistry.
2009 Mar; 393(6-7):1657-68. doi:
10.1007/s00216-009-2623-1. [PMID: 19205672] - Sandhya Sankaranarayanan, John F Oram, Bela F Asztalos, Ashley M Vaughan, Sissel Lund-Katz, Maria Pia Adorni, Michael C Phillips, George H Rothblat. Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux.
Journal of lipid research.
2009 Feb; 50(2):275-84. doi:
10.1194/jlr.m800362-jlr200. [PMID: 18827283] - Xi Zhang, Shelagh M Ferguson-Miller, Gavin E Reid. Characterization of ornithine and glutamine lipids extracted from cell membranes of Rhodobacter sphaeroides.
Journal of the American Society for Mass Spectrometry.
2009 Feb; 20(2):198-212. doi:
10.1016/j.jasms.2008.08.017. [PMID: 18835523] - David L Morse, Danielle Carroll, Sam Day, Heather Gray, Pooja Sadarangani, Shiva Murthi, Constantin Job, Brenda Baggett, Natarajan Raghunand, Robert J Gillies. Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.
NMR in biomedicine.
2009 Jan; 22(1):114-27. doi:
10.1002/nbm.1318. [PMID: 19016452] - Daryl Cox, Lisa Fox, Runying Tian, Wilfried Bardet, Matthew Skaley, Danijela Mojsilovic, Jenny Gumperz, William Hildebrand. Determination of cellular lipids bound to human CD1d molecules.
PloS one.
2009; 4(5):e5325. doi:
10.1371/journal.pone.0005325. [PMID: 19415116] - M Albert Thomas, Scott Lipnick, S Sendhil Velan, Xiaoyu Liu, Shida Banakar, Nader Binesh, Saadallah Ramadan, Art Ambrosio, Raymond R Raylman, James Sayre, Nanette DeBruhl, Lawrence Bassett. Investigation of breast cancer using two-dimensional MRS.
NMR in biomedicine.
2009 Jan; 22(1):77-91. doi:
10.1002/nbm.1310. [PMID: 19086016] - Omnia A Ismaiel, Matthew S Halquist, Magda Y Elmamly, Abdalla Shalaby, H Thomas Karnes. Monitoring phospholipids for assessment of ion enhancement and ion suppression in ESI and APCI LC/MS/MS for chlorpheniramine in human plasma and the importance of multiple source matrix effect evaluations.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 Nov; 875(2):333-43. doi:
10.1016/j.jchromb.2008.08.032. [PMID: 18926779] - Lihong Du, Robert L White. Reducing glycerophosphocholine lipid matrix interference effects in biological fluid assays by using high-turbulence liquid chromatography.
Rapid communications in mass spectrometry : RCM.
2008 Nov; 22(21):3362-70. doi:
10.1002/rcm.3747. [PMID: 18837005] - Wei-Yuan Hou, Ding-Xin Long, Hui-Ping Wang, Qi Wang, Yi-Jun Wu. The homeostasis of phosphatidylcholine and lysophosphatidylcholine was not disrupted during tri-o-cresyl phosphate-induced delayed neurotoxicity in hens.
Toxicology.
2008 Oct; 252(1-3):56-63. doi:
10.1016/j.tox.2008.07.061. [PMID: 18755237] - Demokritos C Tsoukatos, Isabelle Brochériou, Vassilios Moussis, Christina P Panopoulou, Elena D Christofidou, Stamatis Koussissis, Socratis Sismanidis, Ewa Ninio, Stavros Siminelakis. Platelet-activating factor acetylhydrolase and transacetylase activities in human aorta and mammary artery.
Journal of lipid research.
2008 Oct; 49(10):2240-9. doi:
10.1194/jlr.m800188-jlr200. [PMID: 18587071] - M Sterin, I Ringel, S Lecht, P I Lelkes, P Lazarovici. 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: I. The effect of glial cells and valproic acid on phosphometabolite levels.
Endothelium : journal of endothelial cell research.
2008 Sep; 15(5-6):288-98. doi:
10.1080/10623320802487841. [PMID: 19065320] - I Ringel, S Lecht, M Sterin, P I Lelkes, P Lazarovici. 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel constructs as an enabling platform technology: II. The effect of anti-inflammatory drugs on phosphometabolite levels.
Endothelium : journal of endothelial cell research.
2008 Sep; 15(5-6):299-307. doi:
10.1080/10623320802487874. [PMID: 19065321] - Kjell Stålberg, Andrea C Neal, Hans Ronne, Ulf Ståhl. Identification of a novel GPCAT activity and a new pathway for phosphatidylcholine biosynthesis in S. cerevisiae.
Journal of lipid research.
2008 Aug; 49(8):1794-806. doi:
10.1194/jlr.m800129-jlr200. [PMID: 18430972] - Jasmina Saric, Jia V Li, Yulan Wang, Jennifer Keiser, Jake G Bundy, Elaine Holmes, Jürg Utzinger. Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery.
PLoS neglected tropical diseases.
2008 Jul; 2(7):e254. doi:
10.1371/journal.pntd.0000254. [PMID: 18596973] - Jani Saarela, Gerlinde Jung, Marcela Hermann, Johannes Nimpf, Wolfgang J Schneider. The patatin-like lipase family in Gallus gallus.
BMC genomics.
2008 Jun; 9(?):281. doi:
10.1186/1471-2164-9-281. [PMID: 18549477] - Basant K Puri, Serena J Counsell, Brian M Ross, Gavin Hamilton, Marcelo G Bustos, Ian H Treasaden. Evidence from in vivo 31-phosphorus magnetic resonance spectroscopy phosphodiesters that exhaled ethane is a biomarker of cerebral n-3 polyunsaturated fatty acid peroxidation in humans.
BMC psychiatry.
2008 Apr; 8 Suppl 1(?):S2. doi:
10.1186/1471-244x-8-s1-s2. [PMID: 18433512] - Jennifer J Bedford, John P Leader, Rena Jing, Logan J Walker, Janet D Klein, Jeff M Sands, Robert J Walker. Amiloride restores renal medullary osmolytes in lithium-induced nephrogenic diabetes insipidus.
American journal of physiology. Renal physiology.
2008 Apr; 294(4):F812-20. doi:
10.1152/ajprenal.00554.2007. [PMID: 18216143] - Nicholas E Manicke, Justin M Wiseman, Demian R Ifa, R Graham Cooks. Desorption electrospray ionization (DESI) mass spectrometry and tandem mass spectrometry (MS/MS) of phospholipids and sphingolipids: ionization, adduct formation, and fragmentation.
Journal of the American Society for Mass Spectrometry.
2008 Apr; 19(4):531-43. doi:
10.1016/j.jasms.2007.12.003. [PMID: 18258448] - F Klaus, M Palmada, R Lindner, J Laufer, S Jeyaraj, F Lang, C Boehmer. Up-regulation of hypertonicity-activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1.
The Journal of physiology.
2008 Mar; 586(6):1539-47. doi:
10.1113/jphysiol.2007.146191. [PMID: 18202099] - Christian M Abratte, Wei Wang, Rui Li, David J Moriarty, Marie A Caudill. Folate intake and the MTHFR C677T genotype influence choline status in young Mexican American women.
The Journal of nutritional biochemistry.
2008 Mar; 19(3):158-65. doi:
10.1016/j.jnutbio.2007.02.004. [PMID: 17588738] - Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Torbjörn Lundstedt, Per Lek, Serge Rezzi, Ziad Ramadan, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson. Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model.
Molecular systems biology.
2008; 4(?):157. doi:
10.1038/msb4100190. [PMID: 18197175] - Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Serge Rezzi, Ziad Ramadan, Emma Peré-Trepat, Florence Rochat, Christine Cherbut, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model.
Molecular systems biology.
2008; 4(?):205. doi:
10.1038/msb.2008.40. [PMID: 18628745] - Sandrine P Claus, Tsz M Tsang, Yulan Wang, Olivier Cloarec, Eleni Skordi, François-Pierre Martin, Serge Rezzi, Alastair Ross, Sunil Kochhar, Elaine Holmes, Jeremy K Nicholson. Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.
Molecular systems biology.
2008; 4(?):219. doi:
10.1038/msb.2008.56. [PMID: 18854818] - Jost Klawitter, Christopher J Rivard, Lewis M Brown, Juan M Capasso, Nestor E Almeida, Arvid B Maunsbach, Kaarina Pihakaski-Maunsbach, Tomas Berl, Dieter Leibfritz, Uwe Christians, Laurence Chan. A metabonomic and proteomic analysis of changes in IMCD3 cells chronically adapted to hypertonicity.
Nephron. Physiology.
2008; 109(1):p1-10. doi:
10.1159/000129074. [PMID: 18460876] - Lin Guo, Pramit Chowdhury, Jiyu Fang, Feng Gai. Heterogeneous and anomalous diffusion inside lipid tubules.
The journal of physical chemistry. B.
2007 Dec; 111(51):14244-9. doi:
10.1021/jp076562n. [PMID: 18052149] - Qilin Chen, Michael Kazachkov, Zhifu Zheng, Jitao Zou. The yeast acylglycerol acyltransferase LCA1 is a key component of Lands cycle for phosphatidylcholine turnover.
FEBS letters.
2007 Nov; 581(28):5511-6. doi:
10.1016/j.febslet.2007.10.061. [PMID: 17996202] - Fang Fang, Xinhong He, Huiwen Deng, Qun Chen, Jianping Lu, Manfred Spraul, Yihua Yu. Discrimination of metabolic profiles of pancreatic cancer from chronic pancreatitis by high-resolution magic angle spinning 1H nuclear magnetic resonance and principal components analysis.
Cancer science.
2007 Nov; 98(11):1678-82. doi:
10.1111/j.1349-7006.2007.00589.x. [PMID: 17727683] - Fong-Fu Hsu, John Turk. Differentiation of 1-O-alk-1'-enyl-2-acyl and 1-O-alkyl-2-acyl glycerophospholipids by multiple-stage linear ion-trap mass spectrometry with electrospray ionization.
Journal of the American Society for Mass Spectrometry.
2007 Nov; 18(11):2065-73. doi:
10.1016/j.jasms.2007.08.019. [PMID: 17913512]
