Oleamide (BioDeep_00000002283)
Secondary id: BioDeep_00000408474
human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite
Metabolite Card
Formula: C18H35NO (281.27185000000003)
Chinese Names: 油酸酰胺
Spectrum Hits:
Top Source Homo sapiens(blood) 0.02%
Last reviewed on 2024-07-02.
Cite this Page
Oleamide. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/oleamide (retrieved
2024-11-06) (BioDeep RN: BioDeep_00000002283). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Molecular Structure
SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)N
InChI: InChI=1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
Description
Oleamide is an amide of the fatty acid oleic acid. It is an endogenous substance: it occurs naturally in the body of animals. It accumulates in the cerebrospinal fluid during sleep deprivation and induces sleep in animals. It is being studied as a potential medical treatment for mood and sleep disorders, and cannabinoid-regulated depression. The mechanism of action of oleamides sleep inducing effects is an area of current research. It is likely that oleamide interacts with multiple neurotransmitter systems. Oleamide is structurally related to the endogenous cannabinoid anandamide, and has the ability to bind to the CB1 receptor as a full agonist.
Oleamide. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=301-02-0 (retrieved 2024-07-02) (CAS RN: 301-02-0). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
Synonyms
39 synonym names
(cis)-9-Octadecenoic acid amide; (Z)-Octadec-9-enoic acid amide; (Z)-Octadec-9-enoate amide; trans-9,10-Octadecenoamide; (cis)-9-Octadecenoic acid; cis-9,10-Octadecenoamide; Oleylamide, (e)-isomer; (9Z)-Octadec-9-enamide; (cis)-9-Octadecenoate; (9Z)-9-Octadecenamide; (Z)-9-Octadecenamide; 14C-Labeled oleamide; (9Z)-Octadecenamide; 9,10-Octadecenamide; 9Z-octadecenamide; Octadecene amide; 9-Octadecenamide; Oleic acid amide; Aliphatic amide; Petrac slip-eze; Polydis TR 121; Elaidoylamide; Diamide O 200; Crodamide or; Unislip 1759; Oleate amide; Diamit O 200; Oleyl amide; Crodamide O; Armoslip CP; Tocris-0878; Kemamide O; Oleylamide; Adogen 73; Oleamide; Slip-eze; Armid O; Amide O; ELD
Cross Reference
14 cross reference id
- ChEBI: CHEBI:116314
- KEGG: C19670
- PubChem: 5283387
- HMDB: HMDB0002117
- Metlin: METLIN4115
- ChEMBL: CHEMBL15927
- Wikipedia: Oleamide
- foodb: FDB012436
- chemspider: 4446508
- CAS: 301-02-0
- PMhub: MS000002279
- LipidMAPS: LMFA08010004
- RefMet: Oleamide
- medchemexpress: HY-N2327
Classification Terms
Related Pathways
Reactome(0)
BioCyc(0)
PlantCyc(0)
Biological Process
40 related biological process reactions.
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(40)
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- fatty acid α-oxidation I:
H+ + a 2(R)-hydroperoxy fatty acid ⟶ CO2 + H2O + a fatty aldehyde
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain acyl-CoA + diphosphate
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain acyl-CoA + diphosphate
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain acyl-CoA + diphosphate
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- phosphatidylcholine acyl editing:
a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA ⟶ a phosphatidylcholine + coenzyme A
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- fatty acid α-oxidation I:
H+ + a 2(R)-hydroperoxy fatty acid ⟶ CO2 + H2O + a fatty aldehyde
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain acyl-CoA + diphosphate
- fatty acid α-oxidation I:
H2O + NAD+ + a fatty aldehyde ⟶ H+ + NADH + a fatty acid
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain fatty acyl-CoA + diphosphate
- triacylglycerol degradation:
H2O + a 2-acylglycerol ⟶ H+ + a fatty acid + glycerol
- fatty acid α-oxidation I (plants):
H2O + NAD+ + a fatty aldehyde ⟶ H+ + NADH + a fatty acid
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain fatty acyl-CoA + diphosphate
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain fatty acyl-CoA + diphosphate
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- phospholipases:
H2O + a phosphatidylcholine ⟶ H+ + a 1,2-diacyl-sn-glycerol 3-phosphate + choline
- fatty acid α-oxidation I:
H2O + NAD+ + a fatty aldehyde ⟶ H+ + NADH + a fatty acid
- ceramide degradation:
a sphingoid 1-phosphate ⟶ O-phosphoethanolamine + an aldehyde
- phosphatidylcholine acyl editing:
ATP + a long-chain fatty acid + coenzyme A ⟶ AMP + a long-chain fatty acyl-CoA + diphosphate
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
7 organism taxonomy source information
- 1202408 - Desmos cochinchinensis: 10.1080/10575639508043184
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
- 3847 - Glycine max: 10.1002/PMIC.201700366
- 9606 - Homo sapiens: -
- 183589 - Pseudo-nitzschia multistriata: 10.3390/MD18060313
- 5691 - Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
- 29760 - Vitis vinifera: 10.3389/FMICB.2017.00457
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
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"
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