Nitrofurantoin (BioDeep_00000002237)
Secondary id: BioDeep_00000409798
human metabolite blood metabolite
代谢物信息卡片
1-[(Z)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione
化学式: C8H6N4O5 (238.03381860000002)
中文名称: 呋喃妥因, 1-[（5-硝基-2-呋喃基）亚甲基氨基]咪唑烷-2,4-二酮
谱图信息:
最多检出来源 Homo sapiens(blood) 45.71%
分子结构信息
SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
InChI: InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
描述信息
A bacteriostatic or bactericidal agent depending on the concentration and susceptibility of the infecting organism. Nitrofurantoin is active against some gram positive organisms such as S. aureus, S. epidermidis, S. saprophyticus, Enterococcus faecalis, S. agalactiae, group D streptococci, viridians streptococci and Corynebacterium. Its spectrum of activity against gram negative organisms includes E. coli, Enterobacter, Neisseria, Salmonella and Shigella. It may be used as an alternative to trimethoprim/sulfamethoxazole for treating urinary tract infections though it may be less effective at eradicating vaginal bacteria. May also be used in females as prophylaxis against recurrent cystitis related to coitus. Nitrofurantoin is highly stable to the development of bacterial resistance, a property thought to be due to its multiplicity of mechanisms of action.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01X - Other antibacterials > J01XE - Nitrofuran derivatives
C254 - Anti-Infective Agent > C255 - Urinary Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
同义名列表
15 个代谢物同义名
1-[(Z)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione; Hydantoin, 1-(5-nitro-furfurylideneamino)-; Nitrofurantoin, monohydrate; Nitrofurantoin sodium salt; Monohydrate nitrofurantoin; DSSTox_CID_972; Nitrofurantoin; Macrodantin; Furadantine; Furadonine; Furadantin; Furantoin; Furadoine; Nitrofurantoin; 1-[(5-Nitro-2-furanyl)methylideneamino]imidazolidine-2,4-dione
数据库引用编号
24 个数据库交叉引用编号
- ChEBI: CHEBI:184472
- ChEBI: CHEBI:71415
- ChEBI: CHEBI:95222
- KEGG: C07268
- KEGGdrug: D00439
- PubChem: 6604200
- PubChem: 5353830
- PubChem: 4509
- HMDB: HMDB0014836
- Metlin: METLIN1576
- DrugBank: DB00698
- ChEMBL: CHEMBL1515795
- ChEMBL: CHEMBL572
- Wikipedia: Nitrofurantoin
- MeSH: Nitrofurantoin
- chemspider: 4510228
- CAS: 1516934-90-9
- CAS: 178170-37-1
- CAS: 67-20-9
- PMhub: MS000002197
- PubChem: 9477
- PDB-CCD: U6Z
- RefMet: Nitrofurantoin
- KNApSAcK: 71415
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sabina Ramirez-Hincapie, Barbara Birk, Philipp Ternes, Varun Giri, Franziska Maria Zickgraf, Volker Haake, Michael Herold, Hennicke Kamp, Peter Driemert, Robert Landsiedel, Elke Richling, Dorothee Funk-Weyer, Bennard van Ravenzwaay. Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Archives of toxicology.
2023 11; 97(11):2903-2917. doi:
10.1007/s00204-023-03572-7. [PMID: 37665362] - Saumya Singh, Taru Verma, Balaram Khamari, Eswarappa Pradeep Bulagonda, Dipankar Nandi, Siva Umapathy. Antimicrobial Resistance Studies Using Raman Spectroscopy on Clinically Relevant Bacterial Strains.
Analytical chemistry.
2023 08; 95(30):11342-11351. doi:
10.1021/acs.analchem.3c01453. [PMID: 37463121] - Winnie Bao, Mira Koro, Gabriel W Loh, Ana Ortiz. Urinary Tract Infections in Long-term Care: Evaluation of Uropathogens, Antibiotic Susceptibility, and Empiric Treatment.
The Senior care pharmacist.
2022 Jun; 37(6):232-243. doi:
10.4140/tcp.n.2022.232. [PMID: 35610764] - Zuleica Naomi Tano, Renata K Kobayashi, Evelyn Poliana Candido, Juliana Buck Dias, Luis Felipe Perugini, Eliana Carolina Vespero, Wander Rogerio Pavanelli. Susceptibility to first choice antimicrobial treatment for urinary tract infections to Escherichia coli isolates from women urine samples in community South Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases.
2022 May; 26(3):102366. doi:
10.1016/j.bjid.2022.102366. [PMID: 35594950] - Sanjeev Das, Jayashree Konar, Abhra Banerjee, Manas Talukdar. Prevalence of Urinary Tract Infection among Hospitalized Covid 19 Patients: A Study in Eastern India.
The Journal of the Association of Physicians of India.
2022 Mar; 70(3):11-12. doi:
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The Journal of emergency medicine.
2022 03; 62(3):368-377. doi:
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BMC infectious diseases.
2022 Feb; 22(1):194. doi:
10.1186/s12879-022-07167-y. [PMID: 35227203] - Khonaw Kader Salh. Antimicrobial Resistance in Bacteria Causing Urinary Tract Infections.
Combinatorial chemistry & high throughput screening.
2022; 25(7):1219-1229. doi:
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BMJ open.
2021 11; 11(11):e055898. doi:
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Bioresource technology.
2021 Nov; 339(?):125577. doi:
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International urology and nephrology.
2021 Nov; 53(11):2267-2272. doi:
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Journal of colloid and interface science.
2021 Oct; 600(?):537-549. doi:
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Journal of dietary supplements.
2021 Oct; ?(?):1-13. doi:
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International journal of molecular sciences.
2021 Aug; 22(16):. doi:
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Urology.
2021 06; 152(?):142-147. doi:
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Cell reports.
2021 04; 35(4):109040. doi:
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Antimicrobial agents and chemotherapy.
2021 02; 65(3):. doi:
10.1128/aac.00858-20. [PMID: 33361301] - Aykut Akinci, Eralp Kubilay, Vahid Talha Solak, Murat Can Karaburun, Can Utku Baklaci, Ezel Aydoğ, Yakup Tarkan Soygür, Berk Burgu. Effect of continuous antibiotic prophylaxis in children with postoperative JJ stents: A prospective randomized study.
Journal of pediatric urology.
2021 02; 17(1):89-94. doi:
10.1016/j.jpurol.2020.10.004. [PMID: 33097422] - Satoshi Nakagawa, Yusuke Kurimoto, Masayuki Ezumi, Keisuke Nakatani, Shingo Mizunaga, Yuka Yamagishi, Hiroshige Mikamo. In vitro and in vivo antibacterial activity of nitrofurantoin against clinical isolates of E. coli in Japan and evaluation of biological cost of nitrofurantoin resistant strains using a mouse urinary tract infection model.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2021 Feb; 27(2):250-255. doi:
10.1016/j.jiac.2020.09.026. [PMID: 33060044] - B K Anupama, Parth Sampat, Harvir S Gambhir. Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis.
Journal of investigative medicine high impact case reports.
2021 Jan; 9(?):23247096211001659. doi:
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The Journal of small animal practice.
2021 01; 62(1):42-48. doi:
10.1111/jsap.13252. [PMID: 33107048] - Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Elaref Ratemi, Malak Alghamdi, Salah Abusnana, Tarek Kashour, Qutayba Hamid, Rabih Halwani. Effect of common medications on the expression of SARS-CoV-2 entry receptors in liver tissue.
Archives of toxicology.
2020 12; 94(12):4037-4041. doi:
10.1007/s00204-020-02869-1. [PMID: 32808185] - Monika Rojewska, Wojciech Smułek, Krystyna Prochaska, Ewa Kaczorek. Combined Effect of Nitrofurantoin and Plant Surfactant on Bacteria Phospholipid Membrane.
Molecules (Basel, Switzerland).
2020 May; 25(11):. doi:
10.3390/molecules25112527. [PMID: 32481761] - Ramaraj Sukanya, Settu Ramki, Shen-Ming Chen. Ultrasound supported synthesis of tantalum carbide integrated functionalized carbon composite for the voltammetric determination of the antibacterial drug nitrofurantoin in pharmaceutical samples.
Mikrochimica acta.
2020 05; 187(6):342. doi:
10.1007/s00604-020-04314-7. [PMID: 32444944] - André C Machado, Luciano Caseli. Interaction of nitrofurantoin with lipid langmuir monolayers as cellular membrane models distinguished with tensiometry and infrared spectroscopy.
Colloids and surfaces. B, Biointerfaces.
2020 Apr; 188(?):110794. doi:
10.1016/j.colsurfb.2020.110794. [PMID: 31972441] - Nesibe Korkmaz, Yunus Gurbuz, Fatih Sandikci, Gülnur Kul, Emin Ediz Tutuncu, Irfan Sencan. The Role of Ciprofloxacin Resistance and Extended-spectrum beta-lactamase (ESBL) Positivity in Infective Complications Following Prostate Biopsy.
Urology journal.
2020 03; 17(2):192-197. doi:
10.22037/uj.v0i0.4755. [PMID: 31364100] - Feng Zhang, Jinjin Ma, Shanshan Huang, Yaoyao Li. A mechanical stability enhanced luminescence lanthanide MOF test strip encapsulated with polymer net for detecting picric acid and macrodantin.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Mar; 228(?):117816. doi:
10.1016/j.saa.2019.117816. [PMID: 31771909] - Nonkululeko H Zuma, Frans J Smit, Ronnett Seldon, Janine Aucamp, Audrey Jordaan, Digby F Warner, David D N'Da. Single-step synthesis and in vitro anti-mycobacterial activity of novel nitrofurantoin analogues.
Bioorganic chemistry.
2020 03; 96(?):103587. doi:
10.1016/j.bioorg.2020.103587. [PMID: 32044516] - Xin-Yi Teoh, Fatin Nasuha Bt Mahyuddin, Waqas Ahmad, Siok-Yee Chan. Formulation strategy of nitrofurantoin: co-crystal or solid dispersion?.
Pharmaceutical development and technology.
2020 Feb; 25(2):245-251. doi:
10.1080/10837450.2019.1689401. [PMID: 31690150] - Robin Bruyndonckx, Katrien Latour, Glory Abong Atud, Patrick Dubovy, Stijn Jaspers, Niel Hens, Boudewijn Catry, Herman Goossens, Samuel Coenen. Time trend of prevalence and susceptibility to nitrofurantoin of urinary MDR Escherichia coli from outpatients.
The Journal of antimicrobial chemotherapy.
2019 11; 74(11):3264-3267. doi:
10.1093/jac/dkz323. [PMID: 31377782] - Megan S Bradley, Richard H Beigi, Jonathan P Shepherd. A cost-minimization analysis of treatment options for postmenopausal women with dysuria.
American journal of obstetrics and gynecology.
2019 11; 221(5):505.e1-505.e7. doi:
10.1016/j.ajog.2019.04.031. [PMID: 31055032] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Rixt A Wijma, Angela Huttner, Sven van Dun, Wendy Kloezen, Iain J Abbott, Anouk E Muller, Birgit C P Koch, Johan W Mouton. Urinary antibacterial activity of fosfomycin and nitrofurantoin at registered dosages in healthy volunteers.
International journal of antimicrobial agents.
2019 Oct; 54(4):435-441. doi:
10.1016/j.ijantimicag.2019.07.018. [PMID: 31382030] - Jasmine L Gowarty, Ina J Patel, Jon D Herrington. Altered methotrexate clearance in the treatment of CNS lymphoma with concurrent use of nitrofurantoin for a urinary tract infection.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
2019 Oct; 25(7):1794-1797. doi:
10.1177/1078155218813691. [PMID: 30486745] - Erin Seifert Lavelle, Pakeeza Alam, Melanie Meister, Maria Florian-Rodriguez, Cara Elmer-Lyon, Joseph Kowalski, Charelle Carter-Brooks, Donna Mazloomdoost, Halina Zyczynski, Jerry Lowder, Robert Gutman, Gary Sutkin. Antibiotic Prophylaxis During Catheter-Managed Postoperative Urinary Retention After Pelvic Reconstructive Surgery: A Randomized Controlled Trial.
Obstetrics and gynecology.
2019 10; 134(4):727-735. doi:
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Journal of pharmaceutical and biomedical analysis.
2019 Sep; 174(?):161-167. doi:
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Journal of pediatric urology.
2019 Aug; 15(4):378.e1-378.e5. doi:
10.1016/j.jpurol.2019.03.021. [PMID: 31014984] - Qingqing Xu, Jianping Jiang, Zhenhan Zhu, Teng Xu, Zi-Ke Sheng, Meiping Ye, Xiaogang Xu, Minggui Wang. Efflux pumps AcrAB and OqxAB contribute to nitrofurantoin resistance in an uropathogenic Klebsiella pneumoniae isolate.
International journal of antimicrobial agents.
2019 Aug; 54(2):223-227. doi:
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The journal of spinal cord medicine.
2019 07; 42(4):485-493. doi:
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The Journal of antimicrobial chemotherapy.
2019 06; 74(6):1656-1661. doi:
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Ultrasonics sonochemistry.
2019 Apr; 52(?):391-400. doi:
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International urogynecology journal.
2019 03; 30(3):409-414. doi:
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BMC infectious diseases.
2019 Feb; 19(1):155. doi:
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The Indian journal of medical research.
2019 02; 149(2):185-191. doi:
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The Journal of urology.
2018 10; 200(4):801-808. doi:
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Journal of global antimicrobial resistance.
2018 09; 14(?):90-94. doi:
10.1016/j.jgar.2018.03.004. [PMID: 29581074] - Haroon Ahmed, Daniel Farewell, Nick A Francis, Shantini Paranjothy, Christopher C Butler. Risk of adverse outcomes following urinary tract infection in older people with renal impairment: Retrospective cohort study using linked health record data.
PLoS medicine.
2018 09; 15(9):e1002652. doi:
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Antimicrobial agents and chemotherapy.
2018 08; 62(8):. doi:
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Future microbiology.
2018 08; 13(?):1095-1115. doi:
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Microbial pathogenesis.
2018 Aug; 121(?):1-8. doi:
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American journal of obstetrics and gynecology.
2018 07; 219(1):40-51. doi:
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Annals of clinical microbiology and antimicrobials.
2018 Jun; 17(1):28. doi:
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The Journal of antimicrobial chemotherapy.
2018 06; 73(6):1700-1707. doi:
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Journal of the American Society of Nephrology : JASN.
2018 06; 29(6):1731-1740. doi:
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JAMA.
2018 05; 319(17):1781-1789. doi:
10.1001/jama.2018.3627. [PMID: 29710295] - Robert Pickard, Thomas Chadwick, Yemi Oluboyede, Catherine Brennand, Alexander von Wilamowitz-Moellendorff, Doreen McClurg, Jennifer Wilkinson, Laura Ternent, Holly Fisher, Katherine Walton, Elaine McColl, Luke Vale, Ruth Wood, Mohamed Abdel-Fattah, Paul Hilton, Mandy Fader, Simon Harrison, James Larcombe, Paul Little, Anthony Timoney, James N'Dow, Heather Armstrong, Nicola Morris, Kerry Walker, Nikesh Thiruchelvam. Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: the AnTIC RCT.
Health technology assessment (Winchester, England).
2018 05; 22(24):1-102. doi:
10.3310/hta22240. [PMID: 29766842] - Mohammad Oskooi, Torgny Sunnerhagen, Erik Senneby, Magnus Rasmussen. A prospective observational treatment study of aerococcal urinary tract infection.
The Journal of infection.
2018 04; 76(4):354-360. doi:
10.1016/j.jinf.2017.12.009. [PMID: 29253561] - Rena D Malik, Yuefeng Rose Wu, Alana L Christie, Feras Alhalabi, Philippe E Zimmern. Impact of Allergy and Resistance on Antibiotic Selection for Recurrent Urinary Tract Infections in Older Women.
Urology.
2018 03; 113(?):26-33. doi:
10.1016/j.urology.2017.08.070. [PMID: 29196069] - Dean Ironmonger, Obaghe Edeghere, Neville Q Verlander, Savita Gossain, Susan Hopkins, Bridget Hilton, Peter M Hawkey. Effect of general practice characteristics and antibiotic prescribing on Escherichia coli antibiotic non-susceptibility in the West Midlands region of England: a 4 year ecological study.
The Journal of antimicrobial chemotherapy.
2018 03; 73(3):787-794. doi:
10.1093/jac/dkx465. [PMID: 29309593] - A Sobke, O Makarewicz, M Baier, C Bär, W Pfister, S G Gatermann, M W Pletz, C Forstner. Empirical treatment of lower urinary tract infections in the face of spreading multidrug resistance: in vitro study on the effectiveness of nitroxoline.
International journal of antimicrobial agents.
2018 Feb; 51(2):213-220. doi:
10.1016/j.ijantimicag.2017.10.010. [PMID: 29111434] - Wubalem Desta Seifu, Alemayehu Desalegn Gebissa. Prevalence and antibiotic susceptibility of Uropathogens from cases of urinary tract infections (UTI) in Shashemene referral hospital, Ethiopia.
BMC infectious diseases.
2018 01; 18(1):30. doi:
10.1186/s12879-017-2911-x. [PMID: 29320984] - C O'Halloran, N Walsh, M C O'Grady, L Barry, C Hooton, G D Corcoran, B Lucey. Assessment of the comparability of CLSI, EUCAST and Stokes antimicrobial susceptibility profiles for Escherichia coli uropathogenic isolates.
British journal of biomedical science.
2018 Jan; 75(1):24-29. doi:
10.1080/09674845.2017.1392736. [PMID: 29210602] - William Malcolm, Eilidh Fletcher, Kimberley Kavanagh, Ashutosh Deshpande, Camilla Wiuff, Charis Marwick, Marion Bennie. Risk factors for resistance and MDR in community urine isolates: population-level analysis using the NHS Scotland Infection Intelligence Platform.
The Journal of antimicrobial chemotherapy.
2018 Jan; 73(1):223-230. doi:
10.1093/jac/dkx363. [PMID: 29040608] - S Jorgensen, M Zurayk, S Yeung, J Terry, M Dunn, P Nieberg, A Wong-Beringer. Emergency Department Urinary Antibiograms Differ by Specific Patient Group.
Journal of clinical microbiology.
2017 09; 55(9):2629-2636. doi:
10.1128/jcm.00481-17. [PMID: 28615465] - Sehar Amin, Murtaza F Dhrolia, Abdul Mannan. Trend of Antibiotic Sensitivity of Escherichia Coli in Patients with Urinary Tract Infection.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.
2017 Sep; 27(9):594. doi:
2714. [PMID: 29017686] - B A Cunha, C B Cunha, B Lam, J Giuga, J Chin, V F Zafonte, S Gerson. Nitrofurantoin safety and effectiveness in treating acute uncomplicated cystitis (AUC) in hospitalized adults with renal insufficiency: antibiotic stewardship implications.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology.
2017 Jul; 36(7):1213-1216. doi:
10.1007/s10096-017-2911-1. [PMID: 28155015] - Tomas L Griebling. Re: Evaluation of the Risk of Nitrofurantoin Lung Injury and Its Efficacy in Diminished Kidney Function in Older Adults in a Large Integrated Healthcare System: A Matched Cohort Study.
The Journal of urology.
2017 05; 197(5):1277-1278. doi:
10.1016/j.juro.2017.01.027. [PMID: 29539906] - Rosa Abdissa, Woynshet Haile, Akafete Teklu Fite, Ashenafi Feyisa Beyi, Getahun E Agga, Bedaso Mammo Edao, Fanos Tadesse, Mesula Geloye Korsa, Takele Beyene, Tariku Jibat Beyene, Lieven De Zutter, Eric Cox, Bruno Maria Goddeeris. Prevalence of Escherichia coli O157:H7 in beef cattle at slaughter and beef carcasses at retail shops in Ethiopia.
BMC infectious diseases.
2017 04; 17(1):277. doi:
10.1186/s12879-017-2372-2. [PMID: 28412931] - Mohamed Abdel-Aziz Elzayat, Ashton Barnett-Vanes, Mohamed Farag Elmorsy Dabour, Feng Cheng. Prevalence of undiagnosed asymptomatic bacteriuria and associated risk factors during pregnancy: a cross-sectional study at two tertiary centres in Cairo, Egypt.
BMJ open.
2017 03; 7(3):e013198. doi:
10.1136/bmjopen-2016-013198. [PMID: 28325856] - Mazen S Bader, Mark Loeb, Annie A Brooks. An update on the management of urinary tract infections in the era of antimicrobial resistance.
Postgraduate medicine.
2017 Mar; 129(2):242-258. doi:
10.1080/00325481.2017.1246055. [PMID: 27712137] - Sebastiaan Hermanus Johannes Zegers, Jeanne Dieleman, Tjomme van der Bruggen, Jan Kimpen, Catharine de Jong-de Vos van Steenwijk. The influence of antibiotic prophylaxis on bacterial resistance in urinary tract infections in children with spina bifida.
BMC infectious diseases.
2017 01; 17(1):63. doi:
10.1186/s12879-016-2166-y. [PMID: 28081719] - Kenneth Ebele Izuchukwu, Emmanuel Okwudili Oranu, Goddy Bassey, Ngozi Clare Orazulike. Maternofetal outcome of asymptomatic bacteriuria among pregnant women in a Nigerian Teaching Hospital.
The Pan African medical journal.
2017; 27(?):69. doi:
10.11604/pamj.2017.27.69.10492. [PMID: 28819490] - Yonas Alem Gessese, Dereje Leta Damessa, Mebratenesh Mengistu Amare, Yonas Hailesilassie Bahta, Assalif Demisew Shifera, Fikreslasie Samuel Tasew, Endrias Zewdu Gebremedhin. Urinary pathogenic bacterial profile, antibiogram of isolates and associated risk factors among pregnant women in Ambo town, Central Ethiopia: a cross-sectional study.
Antimicrobial resistance and infection control.
2017; 6(?):132. doi:
10.1186/s13756-017-0289-6. [PMID: 29299306] - Mesut Arici, Salih Kavukcu, Sakine Tuncay Tanriverdi, Aylin Arici, Sedef Gidener, Ayse Gelal, Ozgen Ozer. A New Application Route of Nitrofurantoin: Preparation and Characterization of Novel Transdermal Formulations.
Current drug delivery.
2017; 14(3):394-405. doi:
10.2174/1567201813666160729095229. [PMID: 27480119] - Mahmoud Omidi, Hossein Niknahad, Afshin Mohammadi-Bardbori. Dithiothreitol (DTT) rescues mitochondria from nitrofurantoin-induced mitotoxicity in rat.
Journal of biochemical and molecular toxicology.
2016 Dec; 30(12):588-592. doi:
10.1002/jbt.21825. [PMID: 27373690] - Gaelle Delisle, Caroline Quach, Marc-Christian Domingo, Alexandre A Boudreault, Marie Gourdeau, Harold Bernatchez, Christian Lavallée. Escherichia coli antimicrobial susceptibility profile and cumulative antibiogram to guide empirical treatment of uncomplicated urinary tract infections in women in the province of Québec, 2010-15.
The Journal of antimicrobial chemotherapy.
2016 12; 71(12):3562-3567. doi:
10.1093/jac/dkw302. [PMID: 27494927] - Peter Hoang, Rebecca L Salbu. Updated Nitrofurantoin Recommendations in the Elderly: A Closer Look at the Evidence.
The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists.
2016 Jul; 31(7):381-4. doi:
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Antimicrobial agents and chemotherapy.
2016 05; 60(5):3138-40. doi:
10.1128/aac.02961-15. [PMID: 26883704] - Guillermo V Sanchez, Ahmed Babiker, Ronald N Master, Tony Luu, Anisha Mathur, Jose Bordon. Antibiotic Resistance among Urinary Isolates from Female Outpatients in the United States in 2003 and 2012.
Antimicrobial agents and chemotherapy.
2016 05; 60(5):2680-3. doi:
10.1128/aac.02897-15. [PMID: 26883714] - Jody M Santos, Michael Batech, Mitchell A Pelter, Robert L Deamer. Evaluation of the Risk of Nitrofurantoin Lung Injury and Its Efficacy in Diminished Kidney Function in Older Adults in a Large Integrated Healthcare System: A Matched Cohort Study.
Journal of the American Geriatrics Society.
2016 Apr; 64(4):798-805. doi:
10.1111/jgs.14072. [PMID: 27100576] - Nader Shaikh, Alejandro Hoberman, Ron Keren, Anastasia Ivanova, Nathan Gotman, Russell W Chesney, Myra A Carpenter, Marva Moxey-Mims, Ellen R Wald. Predictors of Antimicrobial Resistance among Pathogens Causing Urinary Tract Infection in Children.
The Journal of pediatrics.
2016 Apr; 171(?):116-21. doi:
10.1016/j.jpeds.2015.12.044. [PMID: 26794472] - Carmen Renard, Marie-Amélie Laigneau, Eric Renaudineau. [Nitrofurantoïne, recommendations to be followed to reduce severe complications occurency risk].
Presse medicale (Paris, France : 1983).
2016 Mar; 45(3):369-71. doi:
10.1016/j.lpm.2016.01.008. [PMID: 26868527] - Masayuki Kimura, Sayaka Mizukami, Yousuke Watanabe, Yasuko Hasegawa-Baba, Nobuhiko Onda, Toshinori Yoshida, Makoto Shibutani. Disruption of spindle checkpoint function in rats following 28 days of repeated administration of renal carcinogens.
The Journal of toxicological sciences.
2016 Feb; 41(1):91-104. doi:
10.2131/jts.41.91. [PMID: 26763396] - Ahmet Salvarci, Mehmet Koroglu, Berna Erayman. Investigation of Antibacterial Activity and Biofilm Formation of Silicones Coated With Minocycline-Rifampicin, Silver Nitrate, and Nitrofurantoin for Short-term Utilization in In Vitro Urinary System Models.
Urology.
2016 Feb; 88(?):66-75. doi:
10.1016/j.urology.2015.10.022. [PMID: 26522971] - Sandra Halwachs, Carsten Kneuer, Katrin Gohlsch, Marian Müller, Vera Ritz, Walther Honscha. The ABCG2 efflux transporter from rabbit placenta: Cloning and functional characterization.
Placenta.
2016 Feb; 38(?):8-15. doi:
10.1016/j.placenta.2015.12.005. [PMID: 26907376] - Anne C C Lee, Mohammad A Quaiyum, Luke C Mullany, Dipak K Mitra, Alain Labrique, Parvez Ahmed, Jamal Uddin, Iftekhar Rafiqullah, Sushil DasGupta, Arif Mahmud, Emilia H Koumans, Parul Christian, Samir Saha, Abdullah H Baqui. Screening and treatment of maternal genitourinary tract infections in early pregnancy to prevent preterm birth in rural Sylhet, Bangladesh: a cluster randomized trial.
BMC pregnancy and childbirth.
2015 Dec; 15(?):326. doi:
10.1186/s12884-015-0724-8. [PMID: 26643558] - Elizabeth B Hirsch, Brian R Raux, Paola C Zucchi, Yisu Kim, Christopher McCoy, James E Kirby, Sharon B Wright, George M Eliopoulos. Activity of fosfomycin and comparison of several susceptibility testing methods against contemporary urine isolates.
International journal of antimicrobial agents.
2015 Dec; 46(6):642-7. doi:
10.1016/j.ijantimicag.2015.08.012. [PMID: 26498988] - Amallia Brair, Philip Toozs-Hobson, Jim Gray. Local audit: How tightly should we police antibiotic prescribing for urinary tract infection and how should we modify national policy?.
Post reproductive health.
2015 Dec; 21(4):151-7. doi:
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Urology.
2015 Sep; 86(3):492-7. doi:
10.1016/j.urology.2015.05.033. [PMID: 26163810] - Caroline Schneeberger, Suzanne E Geerlings, Philippa Middleton, Caroline A Crowther. Interventions for preventing recurrent urinary tract infection during pregnancy.
The Cochrane database of systematic reviews.
2015 Jul; ?(7):CD009279. doi:
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The Journal of antimicrobial chemotherapy.
2015 Jul; 70(7):1989-92. doi:
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CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.
2015 Jun; 187(9):648-656. doi:
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European journal of pediatrics.
2015 Jun; 174(6):783-90. doi:
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Toxicology.
2015 May; 331(?):125-35. doi:
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The Indian journal of medical research.
2015 Apr; 141(4):473-7. doi:
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Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
2015 Apr; 21(4):344.e1-11. doi:
10.1016/j.cmi.2014.11.016. [PMID: 25658522] - Burke A Cunha, Philip Lee, Nicole Kaouris, Muhammad Raza. The safety of nitrofurantoin for the treatment of nosocomial catheter-associated bacteriuria (CAB) and cystitis.
Journal of chemotherapy (Florence, Italy).
2015 Feb; 27(2):122-3. doi:
10.1179/1973947814y.0000000202. [PMID: 25004793] - Qing-Yong Wang, Rong-Hai Li, Xiao-Hong Shang. Urinary tract infection caused by Enterococcus isolates: aetiology and antimicrobial resistance patterns.
Journal of chemotherapy (Florence, Italy).
2015 Feb; 27(2):117-9. doi:
10.1179/1973947814y.0000000192. [PMID: 24835052] - Bankole H Oladeinde, Richard Omoregie, Oladapo B Oladeinde. Asymptomatic urinary tract infection among pregnant women receiving ante-natal care in a traditional birth home in Benin City, Nigeria.
Ethiopian journal of health sciences.
2015 Jan; 25(1):3-8. doi:
10.4314/ejhs.v25i1.2. [PMID: 25733779]
