Propazine (BioDeep_00000002216)
human metabolite blood metabolite Industrial Pollutants
代谢物信息卡片
化学式: C9H16ClN5 (229.1094)
中文名称: 扑灭津, 丙嗪
谱图信息:
最多检出来源 Homo sapiens(blood) 31.49%
分子结构信息
SMILES: c1(nc(nc(n1)Cl)NC(C)C)NC(C)C
InChI: InChI=1S/C9H16ClN5/c1-5(2)11-8-13-7(10)14-9(15-8)12-6(3)4/h5-6H,1-4H3,(H2,11,12,13,14,15)
描述信息
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8960; ORIGINAL_PRECURSOR_SCAN_NO 8958
INTERNAL_ID 842; CONFIDENCE standard compound; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8960; ORIGINAL_PRECURSOR_SCAN_NO 8958
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9098; ORIGINAL_PRECURSOR_SCAN_NO 9096
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8923; ORIGINAL_PRECURSOR_SCAN_NO 8922
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8943; ORIGINAL_PRECURSOR_SCAN_NO 8941
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9124; ORIGINAL_PRECURSOR_SCAN_NO 9123
CONFIDENCE standard compound; INTERNAL_ID 842; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8882; ORIGINAL_PRECURSOR_SCAN_NO 8880
CONFIDENCE standard compound; EAWAG_UCHEM_ID 2741
D010575 - Pesticides > D006540 - Herbicides
D016573 - Agrochemicals
同义名列表
14 个代谢物同义名
6-chloro-N2,N4-bis(propan-2-yl)-1,3,5-triazine-2,4-diamine; 6-Chloro-N,n-bis(1-methylethyl)-1,3,5-triazine-2,4-diamine; 6-Chloro-N,n-(1-methylethyl)-[1,3,5]triazine-2,4-diamine; 6-Chloro-N,n-diisopropyl-1,3,5-triazine-2,4-diyldiamine; 6-Chloro-N,n-diisopropyl-1,3,5-triazine-2,4-diamine; 2-Chloro-4,6-bis(isopropylamino)-1,3,5-triazine; 2,4-Bis(isopropylamino)-6-chloro-S-triazine; 2-Chloro-4,6-bis(isopropylamino)-S-triazine; Geigy 30,028; propazine; Prozinex; Gesamil; PPZ; Propazine
数据库引用编号
33 个数据库交叉引用编号
- ChEBI: CHEBI:38067
- KEGG: C14312
- PubChem: 4937
- HMDB: HMDB0256821
- Metlin: METLIN44579
- ChEMBL: CHEMBL1333189
- chemspider: 4768
- CAS: 1655498-05-7
- CAS: 139-40-2
- MoNA: EA274104
- MoNA: LU084202
- MoNA: EA274110
- MoNA: EA274101
- MoNA: EA274108
- MoNA: EA274113
- MoNA: EA274112
- MoNA: EA274111
- MoNA: EA274114
- MoNA: LU084203
- MoNA: LU084205
- MoNA: EA274109
- MoNA: LU084206
- MoNA: EA274106
- MoNA: EA274107
- MoNA: LU084201
- MoNA: EA274102
- MoNA: LU084204
- MoNA: EA274103
- MoNA: EA274105
- PMhub: MS000002148
- PubChem: 17395312
- NIKKAJI: J3.630G
- KNApSAcK: 38067
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Jing Zhang, Ya Kun Wang, Jing Hua Zhou, Fei Xie, Qian Nan Guo, Feng Fan Lu, She Feng Jin, Hong Mei Zhu, Hong Yang. Reduced phytotoxicity of propazine on wheat, maize and rapeseed by salicylic acid.
Ecotoxicology and environmental safety.
2018 Oct; 162(?):42-50. doi:
10.1016/j.ecoenv.2018.06.068. [PMID: 29960913] - M À Olivella, C Bazzicalupi, A Bianchi, N Fiol, I Villaescusa. New insights into the interactions between cork chemical components and pesticides. The contribution of π-π interactions, hydrogen bonding and hydrophobic effect.
Chemosphere.
2015 Jan; 119(?):863-870. doi:
10.1016/j.chemosphere.2014.08.051. [PMID: 25240950] - Margaret Mellon. Weed control: tactics to stamp out herbicide resistance.
Nature.
2014 Jul; 511(7510):410. doi:
10.1038/511410d. [PMID: 25056055] - Sara C Novais, Wim De Coen, Mónica J B Amorim. Gene expression responses linked to reproduction effect concentrations (EC 10,20,50,90) of dimethoate, atrazine and carbendazim, in Enchytraeus albidus.
PloS one.
2012; 7(4):e36068. doi:
10.1371/journal.pone.0036068. [PMID: 22558331] - Markus Godejohann, Jean-Daniel Berset, Daniel Muff. Non-targeted analysis of wastewater treatment plant effluents by high performance liquid chromatography-time slice-solid phase extraction-nuclear magnetic resonance/time-of-flight-mass spectrometry.
Journal of chromatography. A.
2011 Dec; 1218(51):9202-9. doi:
10.1016/j.chroma.2011.10.051. [PMID: 22098937] - James W Simpkins, James A Swenberg, Noel Weiss, David Brusick, J Charles Eldridge, James T Stevens, Robert J Handa, Russell C Hovey, Tony M Plant, Timothy P Pastoor, Charles B Breckenridge. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence.
Toxicological sciences : an official journal of the Society of Toxicology.
2011 Oct; 123(2):441-59. doi:
10.1093/toxsci/kfr176. [PMID: 21768606] - Cécile Chevrier, Gwendolina Limon, Christine Monfort, Florence Rouget, Ronan Garlantézec, Claire Petit, Gaël Durand, Sylvaine Cordier. Urinary biomarkers of prenatal atrazine exposure and adverse birth outcomes in the PELAGIE birth cohort.
Environmental health perspectives.
2011 Jul; 119(7):1034-41. doi:
10.1289/ehp.1002775. [PMID: 21367690] - Susan C Laws, Michelle Hotchkiss, Janet Ferrell, Saro Jayaraman, Lesley Mills, Walker Modic, Nicole Tinfo, Melanie Fraites, Tammy Stoker, Ralph Cooper. Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2009 Nov; 112(1):78-87. doi:
10.1093/toxsci/kfp190. [PMID: 19690231] - Wen Yi Hua, Erin R Bennett, Xui-Sheng Maio, Chris D Metcalfe, Robert J Letcher. Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River.
Environmental toxicology and chemistry.
2006 Sep; 25(9):2356-65. doi:
10.1897/05-571r.1. [PMID: 16986790] - H Jiang, C Adams. Treatability of chloro-s-triazines by conventional drinking water treatment technologies.
Water research.
2006 May; 40(8):1657-67. doi:
10.1016/j.watres.2006.02.013. [PMID: 16631856] - D Van der Merwe, J E Riviere. Comparative studies on the effects of water, ethanol and water/ethanol mixtures on chemical partitioning into porcine stratum corneum and silastic membrane.
Toxicology in vitro : an international journal published in association with BIBRA.
2005 Feb; 19(1):69-77. doi:
10.1016/j.tiv.2004.06.002. [PMID: 15582358] - Marta Garcés-García, Sergi Morais, Miguel Angel González-Martínez, Rosa Puchades, Angel Maquieira. Rapid immunoanalytical method for the determination of atrazine residues in olive oil.
Analytical and bioanalytical chemistry.
2004 Jan; 378(2):484-9. doi:
10.1007/s00216-003-2242-1. [PMID: 14513198] - Marion Gfrerer, Dieter Martens, Bernd M Gawlik, Thomas Wenzl, Aiqian Zhang, Xie Quan, Cheng Sun, Jingwen Chen, Bernhard Platzer, Ernst Lankmayr, Antonius Kettrup. Triazines in the aquatic systems of the Eastern Chinese Rivers Liao-He and Yangtse.
Chemosphere.
2002 Apr; 47(4):455-66. doi:
10.1016/s0045-6535(01)00320-4. [PMID: 11999621] - I Baranowska, C Pieszko. Determination of selected herbicides and phenols in water and soils by solid-phase extraction and high-performance liquid chromatography.
Journal of chromatographic science.
2000 May; 38(5):211-8. doi:
10.1093/chromsci/38.5.211. [PMID: 10813519]
