Carbosulfan (BioDeep_00000001926)
Secondary id: BioDeep_00001868039
human metabolite blood metabolite
代谢物信息卡片
2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-[(dibutylamino)sulfanyl]-N-methylcarbamate
化学式: C20H32N2O3S (380.2134)
中文名称: 丁硫克百威溶液
谱图信息:
最多检出来源 Homo sapiens(blood) 80%
分子结构信息
SMILES: CCCCN(CCCC)SN(C)C(=O)OC1=CC=CC2=C1OC(C)(C)C2
InChI: InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3
描述信息
C471 - Enzyme Inhibitor > C47792 - Acetylcholinesterase Inhibitor
同义名列表
9 个代谢物同义名
2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-[(dibutylamino)sulfanyl]-N-methylcarbamate; 2,3-dihydro-2,2-Dimethyl-7-benzofuranyl (di-N-butylaminosulfenyl)methylcarbamate; Dibutylaminosulphenylcarbofuran; Dibutylaminosulfenylcarbofuran; Carbosulphan; Carbosulfan; Marshal; Carbosulfan; Carbosulfan
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:38476
- KEGG: C18416
- PubChem: 41384
- HMDB: HMDB0249647
- Metlin: METLIN72224
- ChEMBL: CHEMBL2228572
- Wikipedia: Carbosulfan
- chemspider: 37764
- CAS: 55285-14-8
- PMhub: MS000001458
- PubChem: 124489090
- KNApSAcK: 38476
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dangqiang Zhu, Na Li, Mengli Zhang, Yuqing Wang, Feng Li, Ting Hou. Hydrolysis enabled specific colorimetric assay of carbosulfan with sensitivity manipulation via metal-doped or metal-free carbon nanozyme.
Biosensors & bioelectronics.
2024 Jan; 243(?):115786. doi:
10.1016/j.bios.2023.115786. [PMID: 37883845] - Lihong Shi, Hongbin Lang, Jiatao Shen, Fan Shen, Jialu Song, Luqing Zhang, Hua Fang, Yunlong Yu. Absorption, metabolism and distribution of carbosulfan in maize plants (Zea mays L.).
Pest management science.
2023 May; ?(?):. doi:
10.1002/ps.7586. [PMID: 37245216] - Wenjuan Yan, Xiaomin Lin, Qing Yao, Chen Zhao, Zhixiang Zhang, Hanhong Xu. Arbuscular mycorrhizal fungi improve uptake and control efficacy of carbosulfan on Spodoptera frugiperda in maize plants.
Pest management science.
2021 Jun; 77(6):2812-2819. doi:
10.1002/ps.6314. [PMID: 33538074] - Wencheng Song, Chunhong Jia, Junjie Jing, Ercheng Zhao, Min He, Li Chen, Pingzhong Yu. Residue behavior and dietary intake risk assessment of carbosulfan and its metabolites in cucumber.
Regulatory toxicology and pharmacology : RTP.
2018 Jun; 95(?):250-253. doi:
10.1016/j.yrtph.2018.03.023. [PMID: 29601912] - Christopher Didigwu Nwani, Narottam Das Agrawal, Suchita Raghuvanshi, Amita Jaswal, Sadhana Shrivastava, Neelu Sinha, Grace Onyishi, Sangeeta Shukla. Toxicological effects of carbosulfan in rats: Antioxidant, enzymological, biochemical, and hematological responses.
Toxicology and industrial health.
2016 Jul; 32(7):1335-43. doi:
10.1177/0748233714564243. [PMID: 25564597] - Noel Nesakumar, Swaminathan Sethuraman, Uma Maheswari Krishnan, John Bosco Balaguru Rayappan. Electrochemical acetylcholinesterase biosensor based on ZnO nanocuboids modified platinum electrode for the detection of carbosulfan in rice.
Biosensors & bioelectronics.
2016 Mar; 77(?):1070-7. doi:
10.1016/j.bios.2015.11.010. [PMID: 26562329] - Chang P Zhang, Hong M He, Jian Z Yu, Xiu Q Hu, Ya H Zhu, Qiang Wang. Residues of carbosulfan and its metabolites carbofuran and 3-hydroxy carbofuran in rice field ecosystem in China.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes.
2016; 51(6):351-7. doi:
10.1080/03601234.2015.1120606. [PMID: 26963425] - Ines El-Bini Dhouib, Mohamed Montassar Lasram, Alya Annabi, Najoua Gharbi, Saloua El-Fazaa. A comparative study on toxicity induced by carbosulfan and malathion in Wistar rat liver and spleen.
Pesticide biochemistry and physiology.
2015 Oct; 124(?):21-8. doi:
10.1016/j.pestbp.2015.03.012. [PMID: 26453226] - Ines El-Bini Dhouib, Alya Annabi, Aicha Jrad, Narges El-Golli, Najoua Gharbi, Mohamed M Lasram, Saloua El-Fazaa. Carbosulfan-induced oxidative damage following subchronic exposure and the protective effects of N-acetylcysteine in rats.
General physiology and biophysics.
2015 Jul; 34(3):249-61. doi:
10.4149/gpb_2015005. [PMID: 25926552] - Ines Bini Dhouib, Mohamed Montassar Lasram, Maha Abdeladhim, Najoua Gharbi, Melika Ben Ahmed, Saloua El-Fazaa. Immunosuppression and oxidative stress induced by subchronic exposure to carbosulfan in rat spleen: immunomodulatory and antioxidant role of N-acetylcysteine.
Toxicology mechanisms and methods.
2014 Sep; 24(6):417-27. doi:
10.3109/15376516.2014.928764. [PMID: 24916794] - David Banji, Otilia J F Banji, M Ragini, A R Annamalai. Carbosulfan exposure during embryonic period can cause developmental disability in rats.
Environmental toxicology and pharmacology.
2014 Jul; 38(1):230-8. doi:
10.1016/j.etap.2014.05.009. [PMID: 24973665] - Galina Lebedev, Fauzi Abo-Moch, Guy Gafni, David Ben-Yakir, Murad Ghanim. High-level of resistance to spinosad, emamectin benzoate and carbosulfan in populations of Thrips tabaci collected in Israel.
Pest management science.
2013 Feb; 69(2):274-7. doi:
10.1002/ps.3385. [PMID: 22926932] - Yuxian He, Jianwei Zhao, Yu Zheng, Qiyong Weng, Antonio Biondi, Nicolas Desneux, Kongming Wu. Assessment of potential sublethal effects of various insecticides on key biological traits of the tobacco whitefly, Bemisia tabaci.
International journal of biological sciences.
2013; 9(3):246-55. doi:
10.7150/ijbs.5762. [PMID: 23494876] - De-Liang Gao, Wei-Li Yu, Jian-Qiang Miao, Feng Liu. [Toxicity and bioactivity of several alternative nematocides against Ditylenchus destructor].
Ying yong sheng tai xue bao = The journal of applied ecology.
2011 Nov; 22(11):3026-32. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Aug; 879(23):2234-8. doi:
10.1016/j.jchromb.2011.06.006. [PMID: 21723210] - Eliningaya J Kweka, Mramba Nyindo, Franklin Mosha, Ary G Silva. Insecticidal activity of the essential oil from fruits and seeds of Schinus terebinthifolia Raddi against African malaria vectors.
Parasites & vectors.
2011 Jul; 4(?):129. doi:
10.1186/1756-3305-4-129. [PMID: 21729280] - Wen Xie, Shaoli Wang, Qingjun Wu, Yuntao Feng, Huipeng Pan, Xiaoguo Jiao, Long Zhou, Xin Yang, Wei Fu, Haiyuan Teng, Baoyun Xu, Youjun Zhang. Induction effects of host plants on insecticide susceptibility and detoxification enzymes of Bemisia tabaci (Hemiptera: Aleyrodidae).
Pest management science.
2011 Jan; 67(1):87-93. doi:
10.1002/ps.2037. [PMID: 21162148] - Erol Capkin, Ertugrul Terzi, Halis Boran, Ilhan Yandi, Ilhan Altinok. Effects of some pesticides on the vital organs of juvenile rainbow trout (Oncorhynchus mykiss).
Tissue & cell.
2010 Dec; 42(6):376-82. doi:
10.1016/j.tice.2010.10.001. [PMID: 21051065] - Rosemary Castorina, Asa Bradman, Laura Fenster, Dana Boyd Barr, Roberto Bravo, Michelle G Vedar, Martha E Harnly, Thomas E McKone, Ellen A Eisen, Brenda Eskenazi. Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANES.
Environmental health perspectives.
2010 Jun; 118(6):856-63. doi:
10.1289/ehp.0901568. [PMID: 20129873] - Yuntao Feng, Qingjun Wu, Shaoli Wang, Xiaoli Chang, Wen Xie, Baoyun Xu, Youjun Zhang. Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).
Pest management science.
2010 Mar; 66(3):313-8. doi:
10.1002/ps.1877. [PMID: 19937914] - Jérôme Carletto, Thibaud Martin, Flavie Vanlerberghe-Masutti, Thierry Brévault. Insecticide resistance traits differ among and within host races in Aphis gossypii.
Pest management science.
2010 Mar; 66(3):301-7. doi:
10.1002/ps.1874. [PMID: 19908228] - Hari C Meher, Vijay T Gajbhiye, Ghanendra Singh, Anju Kamra, Gautam Chawla. Persistence and nematicidal efficacy of carbosulfan, cadusafos, phorate, and triazophos in soil and uptake by chickpea and tomato crops under tropical conditions.
Journal of agricultural and food chemistry.
2010 Feb; 58(3):1815-22. doi:
10.1021/jf903609d. [PMID: 20085277] - Hari C Meher, Vijay T Gajbhiye, Gautam Chawla, Ghanendra Singh. Virulence development and genetic polymorphism in Meloidogyne incognita (Kofoid & White) Chitwood after prolonged exposure to sublethal concentrations of nematicides and continuous growing of resistant tomato cultivars.
Pest management science.
2009 Nov; 65(11):1201-7. doi:
10.1002/ps.1810. [PMID: 19562824] - Shuang Wu, Wei Dou, Jing-Jing Wu, Jin-Jun Wang. Purification and partial characterization of glutathione S-transferase from insecticide-resistant field populations of Liposcelis paeta Pearman (Psocoptera: Liposcelididae).
Archives of insect biochemistry and physiology.
2009 Feb; 70(2):136-50. doi:
10.1002/arch.20285. [PMID: 19140127] - Sara Sánchez-Moreno, Elena Alonso-Prados, J Luis Alonso-Prados, José M García-Baudín. Multivariate analysis of toxicological and environmental properties of soil nematicides.
Pest management science.
2009 Jan; 65(1):82-92. doi:
10.1002/ps.1650. [PMID: 18823060] - A S A Saad, M A Massoud, A A M Abdel-Megeed, N A Hamid, A K K Mourad, A S T Barakat. Abamectin, pymetrozine and azadirachtin sequence as a unique solution to control the leafminer Liriomyza trifolii (Burgess) (Diptera: Agromyzidae) infesting garden beans (Phaseolus vulgaris L.) in Egypt.
Communications in agricultural and applied biological sciences.
2007; 72(3):583-93. doi:
. [PMID: 18399491] - A S S Saad, M A Massoud, A A M Abdel-Megeed, A K K Mourad, N A Hamid, A S T Barakat. An approach for IPM program to control sucking pests infesting garden bean plants (Phaseolus vulgaris L.) in Egypt.
Communications in agricultural and applied biological sciences.
2007; 72(3):565-81. doi:
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Communications in agricultural and applied biological sciences.
2007; 72(2):109-15. doi:
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Journal of environmental biology.
2006 May; 27(2 Suppl):423-6. doi:
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Ecotoxicology and environmental safety.
2006 Feb; 63(2):268-74. doi:
10.1016/j.ecoenv.2004.12.002. [PMID: 16677910] - Cristina S Bastos, Raul P de Almeida, Fábio A Suinaga. Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts.
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2006 Jan; 62(1):91-8. doi:
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Pest management science.
2003 Aug; 59(8):865-71. doi:
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