Ascorbic acid 2-sulfate (BioDeep_00001876930)

   


代谢物信息卡片


Ascorbic acid 2-sulfate

化学式: C6H8O9S (255.9889)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(C1C(=C(C(=O)O1)OS(=O)(=O)O)O)O)O
InChI: InChI=1S/C6H8O9S/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13/h2,4,7-9H,1H2,(H,11,12,13)/t2-,4+/m0/s1

描述信息

D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents > D000924 - Anticholesteremic Agents
D009676 - Noxae > D000963 - Antimetabolites

同义名列表

1 个代谢物同义名

Ascorbic acid 2-sulfate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ARSA, CAT, CYP2C19, CYP2C9, CYP2D6, CYP3A4, DBH, NT5C2, PTGS2, TUBB4B, XDH
Peripheral membrane protein 2 ACHE, PTGS2
Endoplasmic reticulum membrane 7 ARSA, CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4, PTGS2
Nucleus 3 ACHE, MPO, TUBB4B
cytosol 4 CAT, NT5C2, TUBB4B, XDH
nucleoplasm 3 ARSA, ATP2B1, MPO
Cell membrane 2 ACHE, ATP2B1
Multi-pass membrane protein 1 ATP2B1
Synapse 3 ACHE, ATP2B1, DBH
cell surface 2 ACHE, ARSB
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 ACHE
lysosomal membrane 2 EGF, GAA
neuromuscular junction 1 ACHE
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 NT5C2
Lysosome 5 ARSA, ARSB, GAA, GALNS, MPO
acrosomal vesicle 1 ARSA
endosome 1 ARSA
plasma membrane 6 ACHE, ATP2B1, CYP2C19, CYP2C9, EGF, GAA
synaptic vesicle membrane 1 ATP2B1
Membrane 9 ACHE, ATP2B1, CAT, CYP2D6, CYP3A4, DBH, EGF, GAA, HGF
basolateral plasma membrane 1 ATP2B1
caveola 1 PTGS2
extracellular exosome 9 ARSA, ARSB, ATP2B1, CAT, EGF, GAA, GALNS, MPO, TUBB4B
Lysosome membrane 1 GAA
endoplasmic reticulum 4 ARSA, CYP2D6, DBH, PTGS2
extracellular space 7 ACHE, ARSA, DBH, EGF, HGF, MPO, XDH
lysosomal lumen 4 ARSA, ARSB, GAA, GALNS
perinuclear region of cytoplasm 1 ACHE
mitochondrion 2 CAT, CYP2D6
protein-containing complex 2 CAT, PTGS2
intracellular membrane-bounded organelle 10 ATP2B1, CAT, CYP1A2, CYP2C19, CYP2C9, CYP2D6, CYP3A4, DBH, GAA, MPO
Microsome membrane 5 CYP1A2, CYP2C9, CYP2D6, CYP3A4, PTGS2
Secreted 3 ACHE, DBH, GAA
extracellular region 11 ACHE, ARSA, ARSB, CAT, DBH, EGF, GAA, GALNS, HGF, MPO, TUBB4B
Single-pass membrane protein 1 CYP2D6
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
centriolar satellite 1 DBH
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Extracellular vesicle 1 TUBB4B
microtubule cytoskeleton 1 TUBB4B
nucleolus 1 ARSA
Single-pass type II membrane protein 1 DBH
Cytoplasm, cytoskeleton 1 TUBB4B
focal adhesion 1 CAT
microtubule 1 TUBB4B
Peroxisome 2 CAT, XDH
basement membrane 1 ACHE
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
secretory granule 1 MPO
lateral plasma membrane 1 ATP2B1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
neuron projection 1 PTGS2
cell projection 1 ATP2B1
mitotic spindle 1 TUBB4B
cytoskeleton 1 TUBB4B
Nucleus, nucleolus 1 ARSA
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
intercellular bridge 1 TUBB4B
Cytoplasm, cytoskeleton, flagellum axoneme 1 TUBB4B
sperm flagellum 1 TUBB4B
axonemal microtubule 1 TUBB4B
tertiary granule membrane 1 GAA
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
azurophil granule 1 MPO
ficolin-1-rich granule lumen 2 ARSB, CAT
secretory granule lumen 2 CAT, DBH
secretory granule membrane 1 DBH
endoplasmic reticulum lumen 3 ARSA, ARSB, PTGS2
GET complex 1 ARSA
platelet alpha granule lumen 2 EGF, HGF
azurophil granule membrane 1 GAA
azurophil granule lumen 5 ARSA, ARSB, GALNS, MPO, TUBB4B
immunological synapse 1 ATP2B1
clathrin-coated endocytic vesicle membrane 1 EGF
phagocytic vesicle lumen 1 MPO
synaptic cleft 1 ACHE
ficolin-1-rich granule membrane 1 GAA
Cytoplasmic vesicle, secretory vesicle membrane 1 DBH
extrinsic component of external side of plasma membrane 1 ARSA
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen 1 DBH
chromaffin granule lumen 1 DBH
transport vesicle membrane 1 DBH
catalase complex 1 CAT
[Soluble dopamine beta-hydroxylase]: Cytoplasmic vesicle, secretory vesicle lumen 1 DBH
Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane 1 DBH
chromaffin granule membrane 1 DBH
autolysosome lumen 1 GAA
photoreceptor ribbon synapse 1 ATP2B1
[Isoform H]: Cell membrane 1 ACHE


文献列表

  • A Bérczi, R J Caubergs, H Asard. Partial purification and characterization of an ascorbate-reducible b-type cytochrome from the plasma membrane of Arabidopsis thaliana leaves. Protoplasma. 2003 May; 221(1-2):47-56. doi: 10.1007/s00709-002-0060-5. [PMID: 12768341]
  • Itaru Yamamoto, Akihiro Tai, Yoshihito Fujinami, Kenji Sasaki, Shino Okazaki. Synthesis and characterization of a series of novel monoacylated ascorbic acid derivatives, 6-O-acyl-2-O-alpha-D-glucopyranosyl-L-ascorbic acids, as skin antioxidants. Journal of medicinal chemistry. 2002 Jan; 45(2):462-8. doi: 10.1021/jm010379f. [PMID: 11784150]
  • A L Boskey, R D Blank, S B Doty. Vitamin C-sulfate inhibits mineralization in chondrocyte cultures: a caveat. Matrix biology : journal of the International Society for Matrix Biology. 2001 Apr; 20(2):99-106. doi: 10.1016/s0945-053x(01)00116-0. [PMID: 11334711]
  • T Fukuda, H Komatsubara, T Kasai, M Tsujimura. Studies on the ascorbic acid 2-sulfate biosynthesis in rat. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1991; 61(4):325-7. doi: NULL. [PMID: 1806537]
  • K Dabrowski. Absorption of ascorbic acid and ascorbic sulfate and ascorbate metabolism in common carp (Cyprinus carpio L.). Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 1990; 160(5):549-61. doi: 10.1007/bf00258983. [PMID: 2097301]
  • H Senoo, Y Tsukada, T Sato, R Hata. Co-culture of fibroblasts and hepatic parenchymal cells induces metabolic changes and formation of a three-dimensional structure. Cell biology international reports. 1989 Feb; 13(2):197-206. doi: 10.1016/0309-1651(89)90066-0. [PMID: 2720794]
  • C S Tsao, M Young, S M Rose. Quantitative analysis of ascorbic acid-2-sulfate by high-performance liquid chromatography with electrochemical detection. Journal of chromatography. 1984 Jun; 308(?):306-9. doi: 10.1016/s0021-9673(01)87558-0. [PMID: 6746823]
  • B W Tucker, J E Halver. Distribution of ascorbate-2-sulfate and distribution, half-life and turnover rates of [1-14C]ascorbic acid in rainbow trout. The Journal of nutrition. 1984 Jun; 114(6):991-1000. doi: 10.1093/jn/114.6.991. [PMID: 6726482]
  • M Tsujimura, T Fukuda, T Kasai. Studies on the excretion of ascorbic acid 2-sulfate and total vitamin C into human urine after oral administration of ascorbic acid 2-sulfate. Journal of nutritional science and vitaminology. 1982 Oct; 28(5):467-76. doi: 10.3177/jnsv.28.467. [PMID: 7161646]
  • M Terada, S Wakusawa, Y Watanabe, M Kato, M Hayashi, E Hayashi. Effect of l-ascorbate 2-sulfate on fatty liver and hyperlipidemia induced by various treatments in rats and guinea pigs. Journal of nutritional science and vitaminology. 1980; 26(6):521-34. doi: 10.3177/jnsv.26.521. [PMID: 7241235]