3,3-dimethylbenzidine (BioDeep_00001873893)

   


代谢物信息卡片


3,3-dimethylbenzidine

化学式: C14H16N2 (212.1313)
中文名称: 邻联甲苯胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C=CC(=C1)C2=CC(=C(C=C2)N)C)N
InChI: InChI=1S/C14H16N2/c1-9-7-11(3-5-13(9)15)12-4-6-14(16)10(2)8-12/h3-8H,15-16H2,1-2H3

描述信息

同义名列表

2 个代谢物同义名

3,3-dimethylbenzidine; 3,3'-Dimethylbenzidine



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, BTG2, CAT, CCNG1, CDKN1A, ENO2, FTH1, G6PD
Peripheral membrane protein 1 G6PD
Endoplasmic reticulum membrane 1 HSP90B1
Cytoplasmic vesicle, autophagosome 1 FTH1
Nucleus 8 AEN, ALB, BTG2, CCNG1, CDKN1A, FTH1, HSP90B1, SERPINA3
autophagosome 1 FTH1
cytosol 9 ALB, BTG2, CAT, CDKN1A, ENO2, FTH1, G6PD, HSP90B1, MB
dendrite 1 CCNG1
nuclear body 1 CDKN1A
centrosome 1 ALB
nucleoplasm 3 AEN, CCNG1, CDKN1A
Cell membrane 1 ENO2
Synapse 1 C1QA
cell surface 2 C3, TPO
glutamatergic synapse 1 C1QA
Golgi apparatus 1 ALB
Golgi membrane 1 INS
neuronal cell body 1 CCNG1
postsynapse 1 C1QA
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 G6PD
Lysosome 1 FTH1
plasma membrane 4 C3, ENO2, ME2, TPO
Membrane 7 CAT, ENO2, FTH1, G6PD, HSP90B1, ME2, TPO
extracellular exosome 13 ALB, BTG2, C3, CAT, ENO2, FTH1, G6PD, HP, HPR, HPX, HSP90B1, MB, SERPINA3
endoplasmic reticulum 2 ALB, HSP90B1
extracellular space 9 ALB, C3, ENO2, HP, HPR, HPX, INS, SERPINA3, TPO
perinuclear region of cytoplasm 3 CCNG1, CDKN1A, HSP90B1
mitochondrion 2 CAT, ME2
protein-containing complex 5 ALB, C3, CAT, CDKN1A, HSP90B1
intracellular membrane-bounded organelle 3 CAT, G6PD, ME2
Single-pass type I membrane protein 1 TPO
Secreted 6 ALB, C1QA, C3, HP, HPR, INS
extracellular region 11 ALB, C1QA, C3, CAT, FTH1, HP, HPR, HPX, HSP90B1, INS, SERPINA3
cytoplasmic side of plasma membrane 1 G6PD
Single-pass membrane protein 1 ME2
Mitochondrion matrix 1 ME2
mitochondrial matrix 2 CAT, ME2
anchoring junction 1 ALB
centriolar satellite 1 G6PD
photoreceptor inner segment 1 ENO2
nuclear membrane 1 AEN
perikaryon 1 ENO2
nucleolus 2 AEN, CDKN1A
midbody 1 HSP90B1
sarcoplasm 1 MB
focal adhesion 2 CAT, HSP90B1
Peroxisome 1 CAT
collagen trimer 1 C1QA
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 4 C1QA, HPX, HSP90B1, SERPINA3
ciliary basal body 1 ALB
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 6 ALB, C3, HP, HPR, HPX, SERPINA3
endosome lumen 1 INS
Melanosome 1 HSP90B1
sperm plasma membrane 1 HSP90B1
ficolin-1-rich granule lumen 2 CAT, FTH1
secretory granule lumen 4 C3, CAT, INS, SERPINA3
Golgi lumen 1 INS
endoplasmic reticulum lumen 4 ALB, C3, HSP90B1, INS
platelet alpha granule lumen 2 ALB, SERPINA3
specific granule lumen 1 HP
tertiary granule lumen 2 FTH1, HP
transport vesicle 1 INS
azurophil granule lumen 2 C3, SERPINA3
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
Sarcoplasmic reticulum lumen 1 HSP90B1
cyclin-dependent protein kinase holoenzyme complex 2 CCNG1, CDKN1A
spherical high-density lipoprotein particle 1 HPR
endocytic vesicle lumen 3 HP, HPX, HSP90B1
haptoglobin-hemoglobin complex 1 HP
Cytoplasm, sarcoplasm 1 MB
complement component C1 complex 1 C1QA
complement component C1q complex 1 C1QA
extrinsic component of postsynaptic membrane 1 C1QA
extrinsic component of presynaptic membrane 1 C1QA
Autolysosome 1 FTH1
ferritin complex 1 FTH1
catalase complex 1 CAT
phosphopyruvate hydratase complex 1 ENO2
endoplasmic reticulum chaperone complex 1 HSP90B1
PCNA-p21 complex 1 CDKN1A
ciliary transition fiber 1 ALB


文献列表

  • B Shyla, C Vijaya Bhaskar, G Nagendrappa. Iron(III) oxidized nucleophilic coupling of catechol with o-tolidine/p-toluidine followed by 1,10-phenanthroline as new and sensitivity improved spectrophotometric methods for iron present in chemicals, pharmaceutical, edible green leaves, nuts and lake water samples. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2012 Feb; 86(?):152-8. doi: 10.1016/j.saa.2011.09.068. [PMID: 22070994]
  • Shinpei Kawarai, Kenichi Masuda, Keitaro Ohmori, Shinobu Matsuura, Nobutaka Yasuda, Masahiko Nagata, Masahiro Sakaguchi, Hajime Tsujimoto. Cultivation and characterization of canine skin-derived mast cells. The Journal of veterinary medical science. 2010 Feb; 72(2):131-40. doi: 10.1292/jvms.09-0281. [PMID: 19940396]
  • Zhijun Cao, Xueqin Jiang, Wenhua Meng, Qingji Xie, Qin Yang, Ming Ma, Shouzhuo Yao. An EQCM study on the interaction of heparin with the charge-transfer complex generated during o-tolidine electrooxidation: a biosensing mode with a dynamically renewed surface. Biosensors & bioelectronics. 2007 Oct; 23(3):348-54. doi: 10.1016/j.bios.2007.04.016. [PMID: 17548190]
  • Patrudu Makena, King-Thom Chung. Evidence that 4-aminobiphenyl, benzidine, and benzidine congeners produce genotoxicity through reactive oxygen species. Environmental and molecular mutagenesis. 2007 Jun; 48(5):404-13. doi: 10.1002/em.20288. [PMID: 17370336]
  • Klaus Golka, Silke Kopps, Zdislaw W Myslak. Carcinogenicity of azo colorants: influence of solubility and bioavailability. Toxicology letters. 2004 Jun; 151(1):203-10. doi: 10.1016/j.toxlet.2003.11.016. [PMID: 15177655]
  • A K Cook, S D Gilson, W D Fischer, P H Kass. Effect of diet on results obtained by use of two commercial test kits for detection of occult blood in feces of dogs. American journal of veterinary research. 1992 Oct; 53(10):1749-51. doi: NULL. [PMID: 1456513]
  • T G Semak, V P Kurchenko, A T Pikulev. [Status of the antioxidant system and lipid peroxidation in rat liver after poisoning animals with aminobiphenyl]. Biokhimiia (Moscow, Russia). 1991 Oct; 56(10):1806-11. doi: . [PMID: 1777520]
  • B M Goldsmith, J M Hicks. Rhabdomyolysis: two pediatric case reports. Clinical chemistry. 1985 Feb; 31(2):314-7. doi: . [PMID: 3967373]
  • H Matsuda, H Tanaka, B L Blas, J S Noseñas, T Tokawa, S Ohsawa. Evaluation of ELISA with ABTS, 2-2'-azino-di-(3-ethylbenzthiazoline sulfonic acid), as the substrate of peroxidase and its application to the diagnosis of schistosomiasis. The Japanese journal of experimental medicine. 1984 Jun; 54(3):131-8. doi: . [PMID: 6542945]
  • K Tanaka, T Mii, S Marui, I Matsubara, H Igaki. Some aspects of metabolism and mutagenicity of o-tolidine and an o-tolidine-based azo dye. Industrial health. 1982; 20(3):227-35. doi: 10.2486/indhealth.20.227. [PMID: 7174377]
  • K Tanaka. [Urinary metabolites of o-tolidine (3,3'-dimethylbenzidine) and mutagenicity of the metabolites (author's transl)]. Sangyo igaku. Japanese journal of industrial health. 1981 Mar; 23(2):168-9. doi: 10.1539/joh1959.23.168. [PMID: 7265551]
  • R K Lynn, D W Donielson, A M Ilias, J M Kennish, K Wong, H B Matthews. Metabolism of bisazobiphenyl dyes derived from benzidine, 3,3'-dimethylbenzidine or 3,3'-dimethoxybenzidine to carcinogenic aromatic amines in the dog and rat. Toxicology and applied pharmacology. 1980 Nov; 56(2):248-58. doi: 10.1016/0041-008x(80)90296-3. [PMID: 7466824]
  • H M DIETEREN. METABOLISM OF N,N'-DI(ACETOACETYL)-O-TOLIDINE. Archives of environmental health. 1964 Aug; 9(?):167-8. doi: 10.1080/00039896.1964.10663815. [PMID: 14155050]
  • P ENGELBERTZ, E BABEL. [Detection of o-tolidine and of o-dianisidine and their conversion products in urine and in parts of the organs]. Zentralblatt fur Arbeitsmedizin und Arbeitsschutz. 1954 Nov; 4(6):179-83. doi: NULL. [PMID: 14360520]