FF-MAS (BioDeep_00001871940)
Main id: BioDeep_00000008663
代谢物信息卡片
化学式: C29H46O (410.3548)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C12CC[C@@]3([H])C(C)(C)[C@@H](O)CC[C@]3(C)C=1CC[C@]1(C)[C@@]([H])([C@@](C)([H])CC/C=C(\C)/C)CC=C21
InChI: InChI=1S/C29H46O/c1-19(2)9-8-10-20(3)22-12-13-23-21-11-14-25-27(4,5)26(30)16-18-29(25,7)24(21)15-17-28(22,23)6/h9,13,20,22,25-26,30H,8,10-12,14-18H2,1-7H3/t20-,22-,25+,26+,28-,29-/m1/s1
描述信息
同义名列表
27 个代谢物同义名
4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol; 4,4-dimethylcholesta-8,11,24-trien-3beta-ol; Follicular fluid meiosis-activating sterol; 4,4-dimethylcholesta-8,14,24-trienol; ST 29:3;O; FF-MAS; 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol; (3beta,5alpha)-4,4-dimethyl-Cholesta-8,14,24-trien-3-ol; (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol; (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol(Contain up to 15% ?25 isomer); (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol(Contain up to 15% Delta25 isomer); (3beta,5alpha)-4,4-Dimethylcholesta-8,14,24-trien-3-ol(Contain up to 15per cent 25 isomer); (3R,5S,10S,13S,17S)-4,4,10,13-TETRAMETHYL-17-[(2R)-6-METHYLHEPT-5-EN-2-YL]-1,2,3,5,6,7,11,12,16,17-DECAHYDROCYCLOPENTA[A]PHENANTHREN-3-OL; (3S,5R,10S,13R,17R)-4,4,10,13-tetramethyl-17-[(2R)-6-methylhept-5-en-2-yl]-1,2,3,5,6,7,11,12,16,17-decahydrocyclopenta[a]phenanthren-3-ol; 17-(1,5-dimethylhex-4-enyl)-4,4,10,13-tetramethyl-2,3,4,5,6,7, 10,11,12,13,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 4,4-diMeChol-8,14,24-trienol; 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol; 4,4-dimethyl-5a-cholesta-8,14,24-trien-3b-ol; 4,4-Dimethyl-5a-cholesta-8,14,24-trien-3ss-ol; FF-MAS; Follicular Fluid Meiosis-activating Sterol;; 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3-ol; 4,4-dimethyl-cholesta-8,14,24-trienol; 4,4-dimethylcholesta-8,11,24-trienol; 4,4-Dimethylcholesta-8,14,24-trien-3-olato; 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol; 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol; Cholesta-8,14,24-trien-3-ol, 4,4-dimethyl-, (3beta,5alpha)-; follicular fluid meiosis activating sterol
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:17813
- KEGG: C11455
- PubChem: 443212
- ChEMBL: CHEMBL10850
- LipidMAPS: LMST01010149
- CAS: 64284-64-6
- MetaboLights: MTBLC17813
- PubChem: 13626
- 3DMET: B04267
- NIKKAJI: J1.007.648J
- KNApSAcK: 17813
- MeSH: 4,4-dimethylcholesta-8,14,24-trienol
分类词条
相关代谢途径
Reactome(8)
BioCyc(7)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Leonardo Gatticchi, Bruno Cerra, Paolo Scarpelli, Lara Macchioni, Bartolomeo Sebastiani, Antimo Gioiello, Rita Roberti. Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells.
Biochimica et biophysica acta. Molecular and cell biology of lipids.
2017 Sep; 1862(9):842-852. doi:
10.1016/j.bbalip.2017.05.004. [PMID: 28499814] - Fengchao Wang, Jie Yang, Haibin Wang, Guoliang Xia. Gonadotropin-regulated expressions of lanosterol 14alpha-demethylase, sterol Delta14-reductase and C-4 sterol methyl oxidase contribute to the accumulation of meiosis-activating sterol in rabbit gonads.
Prostaglandins & other lipid mediators.
2010 Jun; 92(1-4):25-32. doi:
10.1016/j.prostaglandins.2010.02.002. [PMID: 20193772] - Christian Grøndahl, Jens Breinholt, Philip Wahl, Anthony Murray, Thomas Høst Hansen, Inger Faerge, Carsten E Stidsen, Kirsten Raun, Christa Hegele-Hartung. Physiology of meiosis-activating sterol: endogenous formation and mode of action.
Human reproduction (Oxford, England).
2003 Jan; 18(1):122-9. doi:
10.1093/humrep/deg028. [PMID: 12525452] - I Faerge, C Grøndahl, J L Ottesen, P Hyttel. Autoradiographic localization of specific binding of meiosis-activating sterol to cumulus-oocyte complexes from marmoset, cow, and mouse.
Biology of reproduction.
2001 Feb; 64(2):527-36. doi:
10.1095/biolreprod64.2.527. [PMID: 11159355] - C Grøndahl, T H Hansen, K Marky-Nielsen, J L Ottesen, P Hyttel. Human oocyte maturation in vitro is stimulated by meiosis-activating sterol.
Human reproduction (Oxford, England).
2000 Dec; 15 Suppl 5(?):3-10. doi:
10.1093/humrep/15.suppl_5.3. [PMID: 11263536] - Y Yoshida, C Yamashita, M Noshiro, M Fukuda, Y Aoyama. Sterol 14-demethylase P450 activity expressed in rat gonads: contribution to the formation of mammalian meiosis-activating sterol.
Biochemical and biophysical research communications.
1996 Jun; 223(3):534-8. doi:
10.1006/bbrc.1996.0929. [PMID: 8687430]
