(6aR,6bR,8aS,11R,12aR,14aR)-3-hydroxy-4,6a,6b,8a,11,14a-hexamethyl-7,8,9,11,12,12a,13,14-octahydropicene-2,10-dione (BioDeep_00001870068)
Main id: BioDeep_00000006892
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C28H36O3 (420.2664)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CC2C(CCC3(C2(CCC4(C3=CC=C5C4=CC(=O)C(=C5C)O)C)C)C)(CC1=O)C
InChI: InChI=1S/C28H36O3/c1-16-13-23-25(3,15-21(16)30)9-11-27(5)22-8-7-18-17(2)24(31)20(29)14-19(18)26(22,4)10-12-28(23,27)6/h7-8,14,16,23,31H,9-13,15H2,1-6H3/t16-,23-,25+,26+,27+,28-/m1/s1
描述信息
D000970 - Antineoplastic Agents
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:9602
- KEGG: C08638
- PubChem: 441687
- CAS: 50802-21-6
- PubChem: 10831
- KNApSAcK: C00003759
- 3DMET: B02291
- NIKKAJI: J10.251B
- KNApSAcK: 9602
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
21 个相关的物种来源信息
- 123397 - Acanthothamnus aphyllus: 10.1016/S0031-9422(00)89810-6
- 123405 - Catha edulis: 10.1016/0305-1978(86)90005-0
- 123388 - Cheiloclinium cognatum: 10.1016/J.PHYTOCHEM.2004.03.039
- 1004000 - Elaeodendron croceum:
- 1089406 - Euonymus tingens: 10.1039/P19730002721
- 489987 - Gymnosporia cassinoides:
- 1237601 - Gymnosporia nemorosa: 10.1016/S0031-9422(00)80396-9
- 123425 - Hippocratea volubilis: 10.1055/S-2006-960066
- 123430 - Maytenus:
- 2822244 - Maytenus canariensis:
- 1825833 - Maytenus chubutensis: 10.1515/ZNC-1999-1-223
- 1081521 - Maytenus magellanica: 10.1080/10575639408043900
- 1081529 - Maytenus woodsonii: 10.1080/10575639508043213
- 1825831 - Monteverdia catingarum: 10.1021/NP980359P
- 490012 - Monteverdia spinosa:
- 123445 - Peritassa campestris: 10.1016/S0031-9422(00)00285-5
- 1009589 - Salacia chinensis:
- 1136861 - Salacia petenensis:
- 1565083 - Salacia reticulata: 10.1016/0031-9422(96)00886-2
- 123477 - Semialarium mexicanum:
- 458696 - Tripterygium wilfordii:
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Francesco Caruso, Miriam Rossi, Eric Eberhardt, Molly Berinato, Raiyan Sakib, Felipe Surco-Laos, Haydee Chavez. Maytenus octogona Superoxide Scavenging and Anti-Inflammatory Caspase-1 Inhibition Study Using Cyclic Voltammetry and Computational Docking Techniques.
International journal of molecular sciences.
2023 Jun; 24(13):. doi:
10.3390/ijms241310750. [PMID: 37445927] - Mapula Razwinani, Keolebogile Shirley Motaung. The influence of friedelin, resinone, tingenone and betulin of compounds on chondrogenic differentiation of porcine adipose-derived mesenchymal stem cells (pADMSCs).
Biochimie.
2022 May; 196(?):234-242. doi:
10.1016/j.biochi.2022.01.018. [PMID: 35121053] - Ana Carolina B da C Rodrigues, Larissa M Bomfim, Sara P Neves, Milena B P Soares, Rosane B Dias, Ludmila F Valverde, Clarissa A Gurgel Rocha, Emmanoel V Costa, Felipe M A da Silva, Waldireny C Rocha, Hector H F Koolen, Daniel P Bezerra. Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid leukemia HL-60 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Oct; 142(?):112034. doi:
10.1016/j.biopha.2021.112034. [PMID: 34411914] - Camila Hernandes, Lucyene Miguita, Romario Oliveira de Sales, Elisangela de Paula Silva, Pedro Omori Ribeiro de Mendonça, Bruna Lorencini da Silva, Maria de Fatima Guarizo Klingbeil, Monica Beatriz Mathor, Erika Bevilaqua Rangel, Luciana Cavalheiro Marti, Juliana da Silva Coppede, Fabio Daumas Nunes, Ana Maria Soares Pereira, Patricia Severino. Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Maytenus ilicifolia Roots Associated with Down-Regulation of miRNA-27a and miR-20a/miR-17-5p.
Molecules (Basel, Switzerland).
2020 Feb; 25(3):. doi:
10.3390/molecules25030760. [PMID: 32050628] - Clarice de Carvalho Veloso, Vanessa Gregório Rodrigues, Renata Cristina Mendes Ferreira, Lucienir Pains Duarte, Andre Klein, Igor Dimitri Duarte, Thiago Roberto Lima Romero, Andrea de Castro Perez. Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K(+) channels pathway activation in mice.
European journal of pharmacology.
2015 May; 755(?):1-5. doi:
10.1016/j.ejphar.2015.02.038. [PMID: 25748602] - Edson Rodrigues-Filho, Fábio A P Barros, João B Fernandes, Raimundo Braz-Filho. Detection and identification of quinonemethide triterpenes in Peritassa campestris by mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2002; 16(6):627-33. doi:
10.1002/rcm.615. [PMID: 11870901] - W Dymowski, M Furmanowa. [Searching for cytostatic substances in plant tissue of Maytenus molina by in vitro culture. III. Release of substances from active biological fractions from the callus extract of Maytenus wallichiana R. and B].
Acta poloniae pharmaceutica.
1992; 49(1-2):29-33. doi:
. [PMID: 8769078] - W Dymowski, M Furmanowa. [Investigating cytostatic substances in tissue of plants Maytenus Molina in in-vitro cultures. II. chromatographic test of extracts from callus of Maytenus wallichiana R. et B].
Acta poloniae pharmaceutica.
1990; 47(5-6):51-4. doi:
. [PMID: 1669332] - S G Goijman, J F Turrens, G B Marini-Bettolo, A O Stoppani. [Inhibition of growth and macromolecular biosynthesis in Trypanosoma cruzi by natural products. Effects of miconidine and tingenone].
Medicina.
1984; 44(4):361-70. doi:
. [PMID: 6399926]
