4-coumaroyl-CoA (BioDeep_00001869228)

Main id: BioDeep_00000004328

 

PANOMIX_OTCML-2023


代谢物信息卡片


4-coumaroyl-CoA

化学式: C30H42N7O18P3S (913.152)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)C=CC4=CC=C(C=C4)O)O
InChI: InChI=1S/C30H42N7O18P3S/c1-30(2,25(42)28(43)33-10-9-20(39)32-11-12-59-21(40)8-5-17-3-6-18(38)7-4-17)14-52-58(49,50)55-57(47,48)51-13-19-24(54-56(44,45)46)23(41)29(53-19)37-16-36-22-26(31)34-15-35-27(22)37/h3-8,15-16,19,23-25,29,38,41-42H,9-14H2,1-2H3,(H,32,39)(H,33,43)(H,47,48)(H,49,50)(H2,31,34,35)(H2,44,45,46)/t19-,23-,24-,25+,29-/m1/s1

描述信息

The S-(4-coumaroyl) derivative of coenzyme A.

同义名列表

2 个代谢物同义名

4-coumaroyl-CoA; p-Coumaroyl-CoA



数据库引用编号

14 个数据库交叉引用编号

分类词条

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ACADM, CNR1, FTO, GAPDH, PKP2
Peripheral membrane protein 1 CYP1B1
Endoplasmic reticulum membrane 3 CDS2, CYP1B1, HMGCR
Nucleus 7 ACADM, ESCO2, FTO, GAPDH, MYB, PKP2, ZNF79
cytosol 5 CDS2, COMT, FTO, GAPDH, MYB
dendrite 2 ACVRL1, COMT
mitochondrial membrane 1 ACADM
centrosome 1 ANKRD26
nucleoplasm 4 ESCO2, FTO, MYB, PKP2
RNA polymerase II transcription regulator complex 1 MYB
Cell membrane 4 ACVRL1, CCR7, CNR1, COMT
Cell projection, axon 1 CNR1
Multi-pass membrane protein 4 CCR7, CDS2, CNR1, HMGCR
Synapse 2 COMT, NPS
cell junction 2 ESCO2, PKP2
cell surface 3 ACVRL1, CCR7, TNR
glutamatergic synapse 2 CNR1, TNR
Golgi apparatus 1 ESCO2
growth cone 1 CNR1
mitochondrial inner membrane 1 CDS2
neuronal cell body 1 ACVRL1
presynaptic membrane 1 CNR1
Cytoplasm, cytosol 1 GAPDH
Presynapse 1 CNR1
plasma membrane 8 ACVRL1, CCR7, CNR1, COMT, FTO, GAPDH, MUC5B, PKP2
Membrane 8 ACVRL1, CDS2, COMT, CYP1B1, GAPDH, HMGCR, MYB, PKP2
axon 3 ACADM, CNR1, COMT
extracellular exosome 3 COMT, GAPDH, MUC5B
endoplasmic reticulum 2 CDS2, HMGCR
extracellular space 2 MUC5B, TNR
perinuclear region of cytoplasm 1 GAPDH
Schaffer collateral - CA1 synapse 1 TNR
adherens junction 1 PKP2
intercalated disc 1 PKP2
mitochondrion 3 ACADM, CCR7, CYP1B1
protein-containing complex 1 CDS2
intracellular membrane-bounded organelle 5 COMT, CYP1B1, FTO, GAPDH, MUC5B
Microsome membrane 1 CYP1B1
pericentric heterochromatin 1 ESCO2
Single-pass type I membrane protein 1 ACVRL1
extracellular region 2 NPS, TNR
Mitochondrion outer membrane 1 CNR1
mitochondrial outer membrane 1 CNR1
Mitochondrion matrix 1 ACADM
mitochondrial matrix 1 ACADM
Extracellular side 1 COMT
anchoring junction 1 PKP2
nuclear membrane 1 GAPDH
external side of plasma membrane 1 CCR7
Secreted, extracellular space, extracellular matrix 1 TNR
actin cytoskeleton 1 CNR1
microtubule cytoskeleton 1 GAPDH
cell-cell junction 1 PKP2
Single-pass type II membrane protein 1 COMT
vesicle 1 GAPDH
Cytoplasm, perinuclear region 1 GAPDH
Membrane raft 2 CNR1, TNR
Cytoplasm, cytoskeleton 1 GAPDH
GABA-ergic synapse 1 CNR1
extracellular matrix 1 MUC5B
peroxisomal membrane 1 HMGCR
collagen-containing extracellular matrix 1 TNR
intermediate filament 1 PKP2
nuclear speck 1 FTO
chromatin 1 ESCO2
Chromosome 1 ESCO2
cytoskeleton 1 GAPDH
site of double-strand break 1 ESCO2
Lipid droplet 1 GAPDH
Cornified envelope 1 PKP2
Nucleus speckle 1 FTO
Peroxisome membrane 1 HMGCR
Golgi lumen 1 MUC5B
nuclear matrix 1 MYB
XY body 1 ESCO2
perineuronal net 1 TNR
cell tip 1 PKP2
ribonucleoprotein complex 1 GAPDH
chromocenter 1 ESCO2
Cell junction, desmosome 1 PKP2
desmosome 1 PKP2
GAIT complex 1 GAPDH
BMP receptor complex 1 ACVRL1
[Isoform Soluble]: Cytoplasm 1 COMT
[Isoform Membrane-bound]: Cell membrane 1 COMT
tenascin complex 1 TNR


文献列表

  • Frederick G Sunstrum, Hannah L Liu, Sharon Jancsik, Lufiani L Madilao, Joerg Bohlmann, Sandra Irmisch. 4-Coumaroyl-CoA ligases in the biosynthesis of the anti-diabetic metabolite montbretin A. PloS one. 2021; 16(10):e0257478. doi: 10.1371/journal.pone.0257478. [PMID: 34618820]
  • Chomphunuch Songsiriritthigul, Natsajee Nualkaew, James Ketudat-Cairns, Chun Jung Chen. The crystal structure of benzophenone synthase from Garcinia mangostana L. pericarps reveals the basis for substrate specificity and catalysis. Acta crystallographica. Section F, Structural biology communications. 2020 Dec; 76(Pt 12):597-603. doi: 10.1107/s2053230x20014818. [PMID: 33263571]
  • Guangjin Li, Shuhua Zhu, Wenxue Wu, Chang Zhang, Yong Peng, Qingguo Wang, Jingying Shi. Exogenous nitric oxide induces disease resistance against Monilinia fructicola through activating the phenylpropanoid pathway in peach fruit. Journal of the science of food and agriculture. 2017 Jul; 97(9):3030-3038. doi: 10.1002/jsfa.8146. [PMID: 27859285]
  • Huili Guo, Yadong Yang, Feiyan Xue, Hong Zhang, Tiran Huang, Wenbin Liu, Huan Liu, Fenqiang Zhang, Mingfeng Yang, Chunmei Liu, Heshu Lu, Yansheng Zhang, Lanqing Ma. Effect of flexible linker length on the activity of fusion protein 4-coumaroyl-CoA ligase::stilbene synthase. Molecular bioSystems. 2017 Feb; 13(3):598-606. doi: 10.1039/c6mb00563b. [PMID: 28181620]
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  • Alexander M Walker, Robert P Hayes, Buhyun Youn, Wilfred Vermerris, Scott E Sattler, ChulHee Kang. Elucidation of the structure and reaction mechanism of sorghum hydroxycinnamoyltransferase and its structural relationship to other coenzyme a-dependent transferases and synthases. Plant physiology. 2013 Jun; 162(2):640-51. doi: 10.1104/pp.113.217836. [PMID: 23624856]
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  • Jean-Etienne Bassard, Ludovic Richert, Jan Geerinck, Hugues Renault, Frédéric Duval, Pascaline Ullmann, Martine Schmitt, Etienne Meyer, Jerôme Mutterer, Wout Boerjan, Geert De Jaeger, Yves Mely, Alain Goossens, Danièle Werck-Reichhart. Protein-protein and protein-membrane associations in the lignin pathway. The Plant cell. 2012 Nov; 24(11):4465-82. doi: 10.1105/tpc.112.102566. [PMID: 23175744]
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