2,3-Cyclic GMP (BioDeep_00001869079)

Main id: BioDeep_00000006085

 


代谢物信息卡片


2,3-Cyclic GMP

化学式: C10H12N5O7P (345.0474)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(N1C3C4C(C(O3)CO)OP(=O)(O4)O)N=C(NC2=O)N
InChI: InChI=1S/C10H12N5O7P/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-6-5(3(1-16)20-9)21-23(18,19)22-6/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17)/t3-,5-,6-,9-/m1/s1

描述信息

A 2,3-cyclic purine nucleotide in which guanosine is used as the parent nucleoside.

同义名列表

1 个代谢物同义名

2,3-Cyclic GMP



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 ANXA5, CNP, TLR7
Peripheral membrane protein 1 ANXA5
Endosome membrane 2 TLR7, TLR8
Endoplasmic reticulum membrane 2 TLR7, TLR8
Nucleus 1 TRIM33
cytosol 2 ANXA5, NT5E
nucleoplasm 3 ATP2B1, NT5E, TRIM33
Cell membrane 2 ATP2B1, NT5E
Lipid-anchor 1 CNP
Multi-pass membrane protein 2 ATP2B1, RHO
Synapse 2 ATP2B1, CNP
cell surface 1 NT5E
glutamatergic synapse 1 ATP2B1
Golgi apparatus 1 RHO
Golgi membrane 3 RHO, TLR7, TLR8
mitochondrial inner membrane 1 CNP
presynaptic membrane 1 ATP2B1
sarcolemma 1 ANXA5
Lysosome 1 TLR7
endosome 2 TLR7, TLR8
plasma membrane 5 ATP2B1, NT5E, RHO, TLR7, TLR8
synaptic vesicle membrane 1 ATP2B1
Membrane 7 ANXA5, ATP2B1, CNP, NT5E, RHO, TLR7, TLR8
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ANXA5, ATP2B1, CNP, NT5E
endoplasmic reticulum 1 TLR7
extracellular space 2 CNP, IL2
perinuclear region of cytoplasm 1 CNP
intracellular membrane-bounded organelle 1 ATP2B1
Single-pass type I membrane protein 2 TLR7, TLR8
Secreted 1 IL2
extracellular region 2 ANXA5, IL2
mitochondrial outer membrane 1 CNP
ciliary membrane 1 RHO
photoreceptor inner segment 1 RHO
photoreceptor outer segment 1 RHO
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 3 ANXA5, NT5E, TLR8
cell-cell junction 1 RHO
focal adhesion 1 ANXA5
microtubule 1 CNP
collagen-containing extracellular matrix 1 ANXA5
lateral plasma membrane 1 ATP2B1
receptor complex 1 TLR7
Zymogen granule membrane 1 ANXA5
chromatin 1 TRIM33
cell projection 1 ATP2B1
Cell projection, cilium, photoreceptor outer segment 1 RHO
sperm midpiece 1 RHO
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 NT5E
Endomembrane system 2 TLR7, TLR8
microvillus 1 CNP
Melanosome 1 CNP
Golgi-associated vesicle membrane 1 RHO
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 NT5E
pseudopodium 1 CNP
Photoreceptor inner segment membrane 1 RHO
immunological synapse 1 ATP2B1
vesicle membrane 1 ANXA5
endolysosome membrane 2 TLR7, TLR8
photoreceptor outer segment membrane 1 RHO
sperm head plasma membrane 1 RHO
early phagosome 1 TLR7
Cytoplasmic vesicle, phagosome 1 TLR7
photoreceptor disc membrane 1 RHO
myelin sheath abaxonal region 1 CNP
myelin sheath adaxonal region 1 CNP
rod photoreceptor outer segment 1 RHO
endothelial microparticle 1 ANXA5
photoreceptor ribbon synapse 1 ATP2B1


文献列表

  • Jingjing Guo, Jie Wang, Jingrong Fan, Yan Zhang, Wenpei Dong, Chang-Po Chen. Distinct Dynamic and Conformational Features of Human STING in Response to 2'3'-cGAMP and c-di-GMP. Chembiochem : a European journal of chemical biology. 2019 07; 20(14):1838-1847. doi: 10.1002/cbic.201900051. [PMID: 30895657]
  • Edwin K Jackson, Zaichuan Mi, Keri Janesko-Feldman, Travis C Jackson, Patrick M Kochanek. 2',3'-cGMP exists in vivo and comprises a 2',3'-cGMP-guanosine pathway. American journal of physiology. Regulatory, integrative and comparative physiology. 2019 06; 316(6):R783-R790. doi: 10.1152/ajpregu.00401.2018. [PMID: 30789788]