Aucuparin (BioDeep_00001868920)

Main id: BioDeep_00000007682

 

natural product


代谢物信息卡片


Aucuparin

化学式: C14H14O3 (230.0943)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=CC(=C1O)OC)C2=CC=CC=C2
InChI: InChI=1S/C14H14O3/c1-16-12-8-11(9-13(17-2)14(12)15)10-6-4-3-5-7-10/h3-9,15H,1-2H3

描述信息

同义名列表

2 个代谢物同义名

Aucuparin; Aucuparin



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

34 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABCB1, ARG1, ARHGAP45, FPR1, FST, PARVA, SIRT1, SOD1, XDH, ZNF346
Endoplasmic reticulum membrane 1 HSP90B1
Nucleus 9 ARG1, FST, GABPA, HSP90B1, PARVA, PRR7, SIRT1, SOD1, ZNF346
cytosol 8 ARG1, ARHGAP45, HSP90B1, PARVA, PRR7, SIRT1, SOD1, XDH
dendrite 1 PRR7
nucleoplasm 5 GABPA, PRR7, SIRT1, SOD1, ZNF346
Cell membrane 3 ABCB1, FPR1, PRR7
lamellipodium 1 PARVA
ruffle membrane 1 ARHGAP45
Cytoplasmic granule 1 ARG1
Multi-pass membrane protein 2 ABCB1, FPR1
Synapse 1 PRR7
cell surface 1 ABCB1
glutamatergic synapse 1 PRR7
Golgi apparatus 1 ATRN
lysosomal membrane 1 GAA
neuronal cell body 1 SOD1
smooth endoplasmic reticulum 1 HSP90B1
Lysosome 1 GAA
plasma membrane 8 ABCB1, ARHGAP45, ATRN, F2, FPR1, GAA, PARVA, PRR7
Membrane 6 ABCB1, ARHGAP45, FPR1, GAA, HSP90B1, PRR7
apical plasma membrane 1 ABCB1
extracellular exosome 6 ABCB1, ATRN, F2, GAA, HSP90B1, SOD1
Lysosome membrane 1 GAA
endoplasmic reticulum 1 HSP90B1
extracellular space 6 ARG1, ATRN, F2, FST, SOD1, XDH
lysosomal lumen 1 GAA
perinuclear region of cytoplasm 2 HSP90B1, PRR7
mitochondrion 2 SIRT1, SOD1
protein-containing complex 2 HSP90B1, SOD1
intracellular membrane-bounded organelle 1 GAA
chromatin silencing complex 1 SIRT1
Single-pass type I membrane protein 1 ATRN
Secreted 2 F2, GAA
extracellular region 7 ARG1, ARHGAP45, F2, FST, GAA, HSP90B1, SOD1
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 SOD1
actin cytoskeleton 1 PARVA
Z disc 1 PARVA
cytoplasmic vesicle 1 SOD1
nucleolus 2 SIRT1, ZNF346
axon cytoplasm 1 SOD1
midbody 1 HSP90B1
Apical cell membrane 1 ABCB1
Cell projection, ruffle membrane 1 ARHGAP45
Cytoplasm, perinuclear region 1 PRR7
heterochromatin 1 SIRT1
Cell junction, focal adhesion 1 PARVA
Cytoplasm, cytoskeleton 1 PARVA
focal adhesion 2 HSP90B1, PARVA
Peroxisome 2 SOD1, XDH
sarcoplasmic reticulum 1 XDH
Nucleus, PML body 1 SIRT1
PML body 1 SIRT1
mitochondrial intermembrane space 1 SOD1
collagen-containing extracellular matrix 2 F2, HSP90B1
nuclear inner membrane 1 SIRT1
Postsynaptic cell membrane 1 PRR7
dendrite cytoplasm 1 SOD1
chromatin 2 GABPA, SIRT1
Nucleus, nucleolus 1 ZNF346
blood microparticle 1 F2
postsynaptic density, intracellular component 1 PRR7
[Isoform 3]: Secreted 1 ATRN
fibrillar center 1 SIRT1
nuclear envelope 1 SIRT1
Cell projection, dendrite 1 PRR7
tertiary granule membrane 1 GAA
Melanosome 1 HSP90B1
euchromatin 1 SIRT1
sperm plasma membrane 1 HSP90B1
Cytoplasm, myofibril, sarcomere, Z line 1 PARVA
secretory granule lumen 1 ARHGAP45
secretory granule membrane 1 FPR1
Golgi lumen 1 F2
endoplasmic reticulum lumen 2 F2, HSP90B1
specific granule lumen 1 ARG1
azurophil granule membrane 2 FPR1, GAA
Single-pass type III membrane protein 1 PRR7
azurophil granule lumen 2 ARG1, ARHGAP45
postsynaptic density membrane 1 PRR7
Sarcoplasmic reticulum lumen 1 HSP90B1
ficolin-1-rich granule membrane 2 FPR1, GAA
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 ATRN
eNoSc complex 1 SIRT1
rDNA heterochromatin 1 SIRT1
endocytic vesicle lumen 1 HSP90B1
endoplasmic reticulum chaperone complex 1 HSP90B1
autolysosome lumen 1 GAA
[SirtT1 75 kDa fragment]: Cytoplasm 1 SIRT1


文献列表

  • Deepa Teotia, Mariam Gaid, Shashank S Saini, Aparna Verma, Ragothaman M Yennamalli, Satyajeet P Khare, Kiran Ambatipudi, Javid Iqbal Mir, Till Beuerle, Robert Hänsch, Partha Roy, Pawan Kumar Agrawal, Ludger Beerhues, Debabrata Sircar. Cinnamate-CoA ligase is involved in biosynthesis of benzoate-derived biphenyl phytoalexin in Malus × domestica 'Golden Delicious' cell cultures. The Plant journal : for cell and molecular biology. 2019 12; 100(6):1176-1192. doi: 10.1111/tpj.14506. [PMID: 31437324]
  • Stefan Weiß, Benye Liu, Dennis Reckwell, Ludger Beerhues, Traud Winkelmann. Impaired defense reactions in apple replant disease-affected roots of Malus domestica 'M26'. Tree physiology. 2017 12; 37(12):1672-1685. doi: 10.1093/treephys/tpx108. [PMID: 29036594]
  • Debabrata Sircar, Mariam M Gaid, Cornelia Chizzali, Dennis Reckwell, David Kaufholdt, Till Beuerle, Giovanni A L Broggini, Henryk Flachowsky, Benye Liu, Robert Hänsch, Ludger Beerhues. Biphenyl 4-Hydroxylases Involved in Aucuparin Biosynthesis in Rowan and Apple Are Cytochrome P450 736A Proteins. Plant physiology. 2015 Jun; 168(2):428-42. doi: 10.1104/pp.15.00074. [PMID: 25862456]
  • Ki Hyun Kim, Sang Un Choi, Sang Keun Ha, Sun Yeou Kim, Kang Ro Lee. Biphenyls from Berberis koreana. Journal of natural products. 2009 Nov; 72(11):2061-4. doi: 10.1021/np900460j. [PMID: 19813743]
  • Jih-Jung Chen, Chien-Fang Peng, Hung-Yi Huang, Ih-Sheng Chen. Benzopyrans, biphenyls and xanthones from the root of Garcinia linii and their activity against Mycobacterium tuberculosis. Planta medica. 2006 Apr; 72(5):473-7. doi: 10.1055/s-2005-916253. [PMID: 16557464]