Chemical Formula: C14H14O3

Chemical Formula C14H14O3

Found 121 metabolite its formula value is C14H14O3

(R)-Kawain

2H-PYRAN-2-ONE, 5,6-DIHYDRO-4-METHOXY-6-((1E)-2-PHENYLETHENYL)-, (6R)-

C14H14O3 (230.0942894)


Kawain is a member of 2-pyranones and an aromatic ether. Kavain is a natural product found in Piper methysticum, Alnus sieboldiana, and Piper majusculum with data available. See also: Piper methysticum root (part of). (R)-Kawain is found in beverages. (R)-Kawain is found in the roots of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002). Found in the roots of kava (Piper methysticum). FDA advises against use of kava in food due to potential risk of severe liver damage (2002) D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D002491 - Central Nervous System Agents > D000927 - Anticonvulsants (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1].

   

demethylsuberosin

2H-1-Benzopyran-2-one, 7-hydroxy-6-(3-methyl-2-buten-1-yl)-

C14H14O3 (230.0942894)


Demethylsuberosin, also known as 7-hydroxy-6-prenylcoumarin or 7-hydroxy-6-prenyl-1-benzopyran-2-one, is a member of the class of compounds known as 7-hydroxycoumarins. 7-hydroxycoumarins are coumarins that contain one or more hydroxyl groups attached to the C7 position the coumarin skeleton. Demethylsuberosin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Demethylsuberosin can be found in a number of food items such as rice, apple, black radish, and cloudberry, which makes demethylsuberosin a potential biomarker for the consumption of these food products. 7-demethylsuberosin is a hydroxycoumarin that is 7-hydroxycoumarin which is substituted at position 6 by a 3-methylbut-2-en-1-yl group. A natural product found in Citropsis articulata. It has a role as a plant metabolite. Demethylsuberosin is a natural product found in Prangos tschimganica, Limonia acidissima, and other organisms with data available. D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity[1]. Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity[1].

   

Osthenol

7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one, 9CI

C14H14O3 (230.0942894)


Osthenol is a hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. It has a role as a plant metabolite and an antifungal agent. It is functionally related to an umbelliferone. Osthenol is a natural product found in Zanthoxylum beecheyanum, Prangos tschimganica, and other organisms with data available. Isolated from seeds of Apium graveolens. Osthenol is found in many foods, some of which are green vegetables, wild celery, fennel, and angelica. A hydroxycoumarin that is umbelliferone in which the hydrogen at position 8 has been replaced by a prenyl group. Osthenol is found in angelica. Osthenol is isolated from seeds of Apium graveolens. Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 μM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 μM and shows a high selectivity index for hMAO-A versus hMAO-B[1].

   

Naproxen

(+)-(S)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid

C14H14O3 (230.0942894)


Naproxen (INN) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury (like fractures), menstrual cramps, tendonitis, bursitis, and the treatment of primary dysmenorrhea. Naproxen and naproxen sodium are marketed under various trade names including: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan; Naproxen is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury (like fractures), menstrual cramps, tendonitis, bursitis, and the treatment of primary dysmenorrhea. Naproxen and naproxen sodium are marketed under various trade names including: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan. Naproxen was first marketed as the prescription drug Naprosyn in 1976 and naproxen sodium was first marketed under the trade name Anaprox in 1980. It remains a prescription-only drug in much of the world. The U.S. Food and Drug Administration (FDA) approved the use of naproxen sodium as an over-the-counter (OTC) drug in 1991, where OTC preparations are sold under the trade name Aleve. In Australia, small packets of lower-strength preparations of naproxen sodium are Schedule 2 Pharmacy Medicines; Naproxen is a member of the 2-arylpropionic acid (profen) family of NSAIDs. It is an odorless, white to off-white crystalline substance. It is lipid-soluble, practically insoluble in water with a low pH (below pH 4), while freely soluble in water at 6 pH and above. Naproxen has a melting point of 153 degree centigrade. Naproxen (INN) is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury (like fractures), menstrual cramps, tendonitis, bursitis, and the treatment of primary dysmenorrhea. Naproxen and naproxen sodium are marketed under various trade names including: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan; Naproxen is a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of mild to moderate pain, fever, inflammation and stiffness caused by conditions such as osteoarthritis, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, injury (like fractures), menstrual cramps, tendonitis, bursitis, and the treatment of primary dysmenorrhea. Naproxen and naproxen sodium are marketed under various trade names including: Aleve, Anaprox, Naprogesic, Naprosyn, Naprelan. M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02C - Other gynecologicals > G02CC - Antiinflammatory products for vaginal administration D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents KEIO_ID N018; [MS2] KO009075 D004791 - Enzyme Inhibitors KEIO_ID N018 Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   

Pindone

2-(2,2-dimethylpropanoyl)-2,3-dihydro-1H-indene-1,3-dione

C14H14O3 (230.0942894)


   

Dihydroresveratrol

5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol

C14H14O3 (230.0942894)


A polyphenol metabolite detected in biological fluids [PhenolExplorer] Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1]. Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1].

   

Euparin methyl ether

1-(6-Methoxy-2-prop-1-en-2-yl-1-benzofuran-5-yl)ethanone

C14H14O3 (230.0942894)


   

Aucaparin

3,5-Dimethoxy-(1,1-biphenyl)-4-ol

C14H14O3 (230.0942894)


Aucuparin, also known as 3,5-dimethoxy-(1,1-biphenyl)-4-ol or 2,6-dimethoxy-4-phenylphenol, belongs to biphenyls and derivatives class of compounds. Those are organic compounds containing to benzene rings linked together by a C-C bond. Aucuparin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Aucuparin can be found in loquat and rowanberry, which makes aucuparin a potential biomarker for the consumption of these food products.

   

Demethylbatatasin IV

5-[2-(2-hydroxyphenyl)ethyl]benzene-1,3-diol

C14H14O3 (230.0942894)


Demethylbatatasin IV is found in root vegetables. Demethylbatatasin IV is isolated from Dioscorea alata (greater yam), Dioscorea bulbifera (air potato) and Dioscorea rotundata (white guinea yam) infected with Botryodiplodia theobromae. Isolated from Dioscorea alata (greater yam), Dioscorea bulbifera (air potato) and Dioscorea rotundata (white guinea yam) infected with Botryodiplodia theobromae. Demethylbatatasin IV is found in root vegetables.

   

NOPM

2-(2-Naphthoxy)propionic acid methyl ester

C14H14O3 (230.0942894)


   

Dihydro-resveratrol

5-[2-(4-Hydroxy-phenyl)-ethyl]-benzene-1,3-diol

C14H14O3 (230.0942894)


Dihydroresveratrol is a stilbenol that is 1,1-ethane-1,2-diyldibenzene with hydroxy groups at positions 1, 3 and 4. It has a role as a xenobiotic metabolite and a plant metabolite. Dihydroresveratrol is a natural product found in Blasia pusilla, Dioscorea dumetorum, and other organisms with data available. A stilbenol that is 1,1-ethane-1,2-diyldibenzene with hydroxy groups at positions 1, 3 and 4. Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1]. Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1].

   

Pondaplin

(4Z,9Z)-5-methyl-2,7-dioxabicyclo[9.2.2]pentadeca-1(13),4,9,11,14-pentaen-8-one

C14H14O3 (230.0942894)


Pondaplin is found in alcoholic beverages. Pondaplin is a constituent of the leaves of Annona glabra (pond apple). Constituent of the leaves of Annona glabra (pond apple). Pondaplin is found in alcoholic beverages and fruits.

   

3,3,5-Trihydroxybibenzyl

3,3,5-Trihydroxybibenzyl

C14H14O3 (230.0942894)


   
   

(-)-Kawain

4-methoxy-6-(2-phenylethenyl)-5,6-dihydro-2H-pyran-2-one

C14H14O3 (230.0942894)


   

(R)-Naproxen

2-(6-Methoxynaphthalen-2-yl)propanoic acid

C14H14O3 (230.0942894)


   

VALONE

2-(3-methylbutanoyl)-2,3-dihydro-1H-indene-1,3-dione

C14H14O3 (230.0942894)


   

Naproxen

2-(6-Methoxynaphthalen-2-yl)propanoic acid

C14H14O3 (230.0942894)


M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02C - Other gynecologicals > G02CC - Antiinflammatory products for vaginal administration D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor CONFIDENCE standard compound; EAWAG_UCHEM_ID 202 D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS

   
   

2,3,4-Trihydroxybibenzyl

2,3,4-Trihydroxybibenzyl

C14H14O3 (230.0942894)


   
   

Senoxepin

(9S-cis)-7,8,9,9a-Tetrahydro-9-(1-methylethenyl)-2H-furo[4,3,2-ef][2]benzoxepin-2-one

C14H14O3 (230.0942894)


   
   

2-Hydroxyplatyphyllide

cis-6,7,8,8a-Tetrahydro-4-hydroxy-8-(1-methylethenyl)-2H-naphtho[1,8-bc]furan-2-one

C14H14O3 (230.0942894)


   

Tetrahydromaturinone

(5R)-5,6,7,8-Tetrahydro-3,5-dimethylnaphtho[2,3-b]furan-4,9-dione

C14H14O3 (230.0942894)


   

3,3,4-Trihydroxybibenzyl

3,3,4-Trihydroxybibenzyl

C14H14O3 (230.0942894)


   

7-Isopentenyloxycoumarin

7-Isopentenyloxycoumarin

C14H14O3 (230.0942894)


7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1]. 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1].

   

4,4-Dihydroxydibenzyl ether

4,4-Dihydroxydibenzyl ether

C14H14O3 (230.0942894)


   

3,3-Dihydroxy-5,5-dimethyldiphenyl ether

3,3-Dihydroxy-5,5-dimethyldiphenyl ether

C14H14O3 (230.0942894)


   

6-O-Methyleuparin

6-O-Methyleuparin

C14H14O3 (230.0942894)


   

DIHYDROXANTHYLETIN

DIHYDROXANTHYLETIN

C14H14O3 (230.0942894)


   
   

(E)-3-[2,3-dihydro-2-(1-methylethenyl)-5-benzofuranyl]-2-propenoic acid

(E)-3-[2,3-dihydro-2-(1-methylethenyl)-5-benzofuranyl]-2-propenoic acid

C14H14O3 (230.0942894)


   

1-hydroxyplatyphyllide

1-hydroxyplatyphyllide

C14H14O3 (230.0942894)


   

2,3,4-trihydroxybibenzyl

2,3,4-trihydroxybibenzyl

C14H14O3 (230.0942894)


   

3-[2-(4-Hydroxyphenyl)ethyl]benzene-1,2-diol

3-[2-(4-Hydroxyphenyl)ethyl]benzene-1,2-diol

C14H14O3 (230.0942894)


   

Dihydro-5,6-dehydrokawain

Dihydro-5,6-dehydrokawain

C14H14O3 (230.0942894)


   
   
   

4-(3,5-DIMETHOXYPHENYL)PHENOL

4-(3,5-DIMETHOXYPHENYL)PHENOL

C14H14O3 (230.0942894)


   

2-(4-hydroxybenzyl)-4-(hydroxymethyl)phenol

2-(4-hydroxybenzyl)-4-(hydroxymethyl)phenol

C14H14O3 (230.0942894)


   

(Z)-Eucalyptene|Eucalyptene B

(Z)-Eucalyptene|Eucalyptene B

C14H14O3 (230.0942894)


   
   

Ethanone, 1-(1-hydroxy-8-methoxy-3-methyl-2-naphthalenyl)-

Ethanone, 1-(1-hydroxy-8-methoxy-3-methyl-2-naphthalenyl)-

C14H14O3 (230.0942894)


   

2beta-(2,4-hexadiynoyl)-1,6-dioxaspiro<4.5>deca-3-ene|2beta-(2,4-hexadiynoyl)-1,6-dioxaspiro[4.5]deca-3-ene

2beta-(2,4-hexadiynoyl)-1,6-dioxaspiro<4.5>deca-3-ene|2beta-(2,4-hexadiynoyl)-1,6-dioxaspiro[4.5]deca-3-ene

C14H14O3 (230.0942894)


   

6-(1,1-dimethyl-2-propenyl)-7-hydroxycoumarin

6-(1,1-dimethyl-2-propenyl)-7-hydroxycoumarin

C14H14O3 (230.0942894)


   

2-(3,5-dimethoxyphenyl)phenol

2-(3,5-dimethoxyphenyl)phenol

C14H14O3 (230.0942894)


   
   
   

2-[(Z)-2,4-hexadiynylidene]-7-hydroxymethyl-1,6-dioxaspiro[4.4]non-3-ene|dendrazawayne B

2-[(Z)-2,4-hexadiynylidene]-7-hydroxymethyl-1,6-dioxaspiro[4.4]non-3-ene|dendrazawayne B

C14H14O3 (230.0942894)


   

5,6-Dehydrokawain

5,6-Dehydrokawain

C14H14O3 (230.0942894)


   
   

6-hydroxy-2-isopropyl-7-methyl-1,4-naphthoquinone

6-hydroxy-2-isopropyl-7-methyl-1,4-naphthoquinone

C14H14O3 (230.0942894)


   
   
   

Bibenzyl-3,3,4-triol

Bibenzyl-3,3,4-triol

C14H14O3 (230.0942894)


   
   
   

4-[[4-(hydroxymethyl)phenoxy]methyl]phenol

4-[[4-(hydroxymethyl)phenoxy]methyl]phenol

C14H14O3 (230.0942894)


   
   

Diorcinol

Diorcinol

C14H14O3 (230.0942894)


An aromatic ether that is diphenyl ether in which both phenyl groups are substituted at position 3 by a hydroxy group and at position 5 by a methyl group.

   

3-hydroxy-2,5-dimethoxybiphenyl

3-hydroxy-2,5-dimethoxybiphenyl

C14H14O3 (230.0942894)


A natural product found in Rhaphiolepis indica var. tashiroi.

   

7-Prenyloxycoumarin

7-Isopentenyloxycoumarin

C14H14O3 (230.0942894)


7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1]. 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1].

   
   

lenoremycin

7-[(3-methylbut-2-en-1-yl)oxy]-2H-chromen-2-one

C14H14O3 (230.0942894)


7-Prenyloxycoumarin is a natural product found in Coleonema album, Haplopappus multifolius, and other organisms with data available. 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1]. 7-Prenyloxycoumarin (7-O-Prenylumbelliferone) is a secondary metabolite from the endophytic fungus of Annulohypoxylon ilanense[1].

   

Dihydroseselin

InChI=1/C14H14O3/c1-14(2)8-7-10-11(17-14)5-3-9-4-6-12(15)16-13(9)10/h3-6H,7-8H2,1-2H3

C14H14O3 (230.0942894)


   

Naproxen

2-(6-Methoxynaphthalen-2-yl)propanoic acid

C14H14O3 (230.0942894)


M - Musculo-skeletal system > M02 - Topical products for joint and muscular pain > M02A - Topical products for joint and muscular pain > M02AA - Antiinflammatory preparations, non-steroids for topical use M - Musculo-skeletal system > M01 - Antiinflammatory and antirheumatic products > M01A - Antiinflammatory and antirheumatic products, non-steroids > M01AE - Propionic acid derivatives G - Genito urinary system and sex hormones > G02 - Other gynecologicals > G02C - Other gynecologicals > G02CC - Antiinflammatory products for vaginal administration D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D018501 - Antirheumatic Agents > D006074 - Gout Suppressants C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; INTERNAL_ID 2651 CONFIDENCE standard compound; INTERNAL_ID 8544 CONFIDENCE standard compound; INTERNAL_ID 4066

   

NAPROXEN

NCGC00021127-04!NAPROXEN

C14H14O3 (230.0942894)


   

7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one

NCGC00169337-02!7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one

C14H14O3 (230.0942894)


   

Ostenol

Osthenol

C14H14O3 (230.0942894)


Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 μM and shows a high selectivity index for hMAO-A versus hMAO-B[1]. Osthenol (Ostenol), a prenylated coumarin isolated from the dried roots of Angelica pubescens, is selective, reversible, and competitive human monoamine oxidase-A (hMAO-A) inhibitor (Ki=0.26 μM). Osthenol potently inhibits recombinant hMAO-A with an IC50 of 0.74 μM and shows a high selectivity index for hMAO-A versus hMAO-B[1].

   

Kavain

NCGC00091905-05_C14H14O3_(6R)-4-Methoxy-6-[(E)-2-phenylvinyl]-5,6-dihydro-2H-pyran-2-one

C14H14O3 (230.0942894)


D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D002491 - Central Nervous System Agents > D000927 - Anticonvulsants Kawain is a member of 2-pyranones and an aromatic ether. Kavain is a natural product found in Piper methysticum, Alnus sieboldiana, and Piper majusculum with data available. See also: Piper methysticum root (part of). (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. (+)-Kavain, a main kavalactone extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels[1]. (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy[2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied[4]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1]. Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor[1].

   
   

alpha,beta-Dihydroresveratrol

alpha,beta-Dihydroresveratrol

C14H14O3 (230.0942894)


Annotation level-1

   

Dihydroresveratrol

Dihydroresveratrol

C14H14O3 (230.0942894)


Annotation level-1

   

Norpterphyllin III

Norpterphyllin III

C14H14O3 (230.0942894)


   

3,4-dihydro-2,2-dimethyl-pyrano[3,2-c][2]benzopyran-6(2H)-one

3,4-dihydro-2,2-dimethyl-pyrano[3,2-c][2]benzopyran-6(2H)-one

C14H14O3 (230.0942894)


   

Pondaplin

5-methyl-2,7-dioxabicyclo[9.2.2]pentadeca-1(13),4,9,11,14-pentaen-8-one

C14H14O3 (230.0942894)


   

VALONE

2-ISOVALERYLINDAN-1,3-DIONE

C14H14O3 (230.0942894)


   

6-BENZOYL-CYCLOHEX-3-ENECARBOXYLICACID

6-BENZOYL-CYCLOHEX-3-ENECARBOXYLICACID

C14H14O3 (230.0942894)


   

4-trans-Phenylcyclohexane-(1R,2-cis)-dicarboxylic anhydride

4-trans-Phenylcyclohexane-(1R,2-cis)-dicarboxylic anhydride

C14H14O3 (230.0942894)


   

4-hydroxy-3-(2-methylpropyl)naphthalene-1,2-dione

4-hydroxy-3-(2-methylpropyl)naphthalene-1,2-dione

C14H14O3 (230.0942894)


   

3-HYDROXY-8,9,10,11-TETRAHYDRO-7H-CYCLOHEPTACCHROMEN-6-ONE

3-HYDROXY-8,9,10,11-TETRAHYDRO-7H-CYCLOHEPTACCHROMEN-6-ONE

C14H14O3 (230.0942894)


   

Methyl 4-methoxy-7-methyl-2-naphthoate

Methyl 4-methoxy-7-methyl-2-naphthoate

C14H14O3 (230.0942894)


   

Methyl 4-methoxy-6-methyl-2-naphthoate

Methyl 4-methoxy-6-methyl-2-naphthoate

C14H14O3 (230.0942894)


   

Ethyl 4-hydroxy-8-methyl-2-naphthoate

Ethyl 4-hydroxy-8-methyl-2-naphthoate

C14H14O3 (230.0942894)


   

Ethyl 4-hydroxy-6-methyl-2-naphthoate

Ethyl 4-hydroxy-6-methyl-2-naphthoate

C14H14O3 (230.0942894)


   

3-methoxy-4-phenylmethoxyphenol

3-methoxy-4-phenylmethoxyphenol

C14H14O3 (230.0942894)


   

7-Hydroxy-3-prenylcoumarin

7-Hydroxy-3-prenylcoumarin

C14H14O3 (230.0942894)


   

4-[(4-methoxyphenyl)methoxy]phenol

4-[(4-methoxyphenyl)methoxy]phenol

C14H14O3 (230.0942894)


   

(R)-2-METHOXY-2-(NAPHTHALEN-1-YL)PROPANOIC ACID

(R)-2-METHOXY-2-(NAPHTHALEN-1-YL)PROPANOIC ACID

C14H14O3 (230.0942894)


   

Propanoic acid,2-methyl-2-(1-naphthalenyloxy)-

Propanoic acid,2-methyl-2-(1-naphthalenyloxy)-

C14H14O3 (230.0942894)


   

(R)-Naproxen

(R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid

C14H14O3 (230.0942894)


   

2-METHYL-2-(2-NAPHTHYLOXY)PROPANOIC ACID

2-METHYL-2-(2-NAPHTHYLOXY)PROPANOIC ACID

C14H14O3 (230.0942894)


   

2-(4-Phenoxyphenoxy)ethanol

2-(4-Phenoxyphenoxy)ethanol

C14H14O3 (230.0942894)


   

methyl 2-(6-methoxynaphthalen-2-yl)acetate

methyl 2-(6-methoxynaphthalen-2-yl)acetate

C14H14O3 (230.0942894)


   

2H-1-Benzopyran-2-one,4,8-dimethyl-7-(2-propen-1-yloxy)-

2H-1-Benzopyran-2-one,4,8-dimethyl-7-(2-propen-1-yloxy)-

C14H14O3 (230.0942894)


   

3-(5-P-TOLYL-FURAN-2-YL)-PROPIONIC ACID

3-(5-P-TOLYL-FURAN-2-YL)-PROPIONIC ACID

C14H14O3 (230.0942894)


   

2-Methoxy-2-(1-naphthyl)propionic Acid

2-Methoxy-2-(1-naphthyl)propionic Acid

C14H14O3 (230.0942894)


   

4-METHOXY-3-MORPHOLIN-4-YL-BENZOIC ACID

4-METHOXY-3-MORPHOLIN-4-YL-BENZOIC ACID

C14H14O3 (230.0942894)


   

2-[4-(3-oxocyclohexen-1-yl)phenyl]acetic acid

2-[4-(3-oxocyclohexen-1-yl)phenyl]acetic acid

C14H14O3 (230.0942894)


   

3-(5-Benzyl-2-furyl)propanoic acid

3-(5-Benzyl-2-furyl)propanoic acid

C14H14O3 (230.0942894)


   

4,4-OXYBIS(METHOXYBENZENE)

4,4-OXYBIS(METHOXYBENZENE)

C14H14O3 (230.0942894)


   

Ethyl (1-naphthyloxy)acetate

Ethyl (1-naphthyloxy)acetate

C14H14O3 (230.0942894)


   

(S)-2-METHOXY-2-(NAPHTHALEN-1-YL)PROPANOIC ACID

(S)-2-METHOXY-2-(NAPHTHALEN-1-YL)PROPANOIC ACID

C14H14O3 (230.0942894)


   

(Oxydi-2,1-phenylene)dimethanol

(Oxydi-2,1-phenylene)dimethanol

C14H14O3 (230.0942894)


   

4-methoxy-3-phenylmethoxyphenol

4-methoxy-3-phenylmethoxyphenol

C14H14O3 (230.0942894)


   

2H-Pyran-2-one, 4-methoxy-6-(2-phenylethyl)-

2H-Pyran-2-one, 4-methoxy-6-(2-phenylethyl)-

C14H14O3 (230.0942894)


   

7-Hydroxy-3-(2-methylbut-3-en-2-yl)chromen-2-one

7-Hydroxy-3-(2-methylbut-3-en-2-yl)chromen-2-one

C14H14O3 (230.0942894)


   

113276-63-4

5-[2-(2-hydroxyphenyl)ethyl]benzene-1,3-diol

C14H14O3 (230.0942894)


   

58436-28-5

5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol

C14H14O3 (230.0942894)


Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1]. Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1].

   

Bis-(4-hydroxybenzyl)ether

Bis-(4-hydroxybenzyl)ether

C14H14O3 (230.0942894)


An ether in which the oxygen atom is linked to two 4-hydroxybenzyl groups. It is isolated from the tubers of Gastrodia elata and acts as a platelet aggregation inhibitor.

   

2H,5H-Pyrano(3,2-C)(1)benzopyran-5-one, 3,4-dihydro-2,2-dimethyl-

2H,5H-Pyrano(3,2-C)(1)benzopyran-5-one, 3,4-dihydro-2,2-dimethyl-

C14H14O3 (230.0942894)


   

ARQ 501 metabolite M6

ARQ 501 metabolite M6

C14H14O3 (230.0942894)


   

Demethylsuberosin

2H-1-Benzopyran-2-one, 7-hydroxy-6-(3-methyl-2-buten-1-yl)-

C14H14O3 (230.0942894)


7-demethylsuberosin is a hydroxycoumarin that is 7-hydroxycoumarin which is substituted at position 6 by a 3-methylbut-2-en-1-yl group. A natural product found in Citropsis articulata. It has a role as a plant metabolite. Demethylsuberosin is a natural product found in Prangos tschimganica, Limonia acidissima, and other organisms with data available. A hydroxycoumarin that is 7-hydroxycoumarin which is substituted at position 6 by a 3-methylbut-2-en-1-yl group. A natural product found in Citropsis articulata. D011838 - Radiation-Sensitizing Agents > D017319 - Photosensitizing Agents > D011564 - Furocoumarins Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity[1]. Demethylsuberosin (7-Demethylsuberosin) is a coumarin compound isolated from Angelica gigas Nakai, and has anti-inflammatory activity[1].

   
   
   

Demethylbatatasin IV

2,3,5-Trihydroxybibenzyl

C14H14O3 (230.0942894)


   

2-(6-Methoxy-2-naphthyl)propionic acid

2-(6-Methoxynaphthalen-2-yl)propanoic acid

C14H14O3 (230.0942894)


   

(R)-Kawain

(R)-Kawain

C14H14O3 (230.0942894)


D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D002491 - Central Nervous System Agents > D000927 - Anticonvulsants

   

3,3,5-Trihydroxybibenzyl

3,3,5-Trihydroxybibenzyl

C14H14O3 (230.0942894)


A diphenylethane that is 1,2-dihydrostilbene substituted by hydroxy groups at positions 3, 3 and 5.