20-carboxy-Leukotriene B4 (BioDeep_00001868497)

Main id: BioDeep_00000629577

 


代谢物信息卡片


20-hydroxy-20-oxoleukotriene B4

化学式: C20H30O6 (366.2042)
中文名称: 20-羧基白三烯B4
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(CCC(=O)O)CC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O
InChI: InChI=1S/C20H30O6/c21-17(11-6-2-1-3-9-15-19(23)24)12-7-4-5-8-13-18(22)14-10-16-20(25)26/h2,4-8,12-13,17-18,21-22H,1,3,9-11,14-16H2,(H,23,24)(H,25,26)/b5-4+,6-2-,12-7+,13-8-/t17-,18-/m1/s1

描述信息

同义名列表

2 个代谢物同义名

20-hydroxy-20-oxoleukotriene B4; 20-carboxy-Leukotriene B4



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(4)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ALB, ALDH3A2, ALOX5, FPR1, GTPBP4, HIF3A
Peripheral membrane protein 1 ALOX5
Endoplasmic reticulum membrane 1 ALDH3A2
Nucleus 3 ALB, GTPBP4, HIF3A
cytosol 8 AKR1A1, ALB, ALDH3A2, ALOX5, EPHX2, GTPBP4, HIF3A, PRKCQ
dendrite 1 ACVRL1
centrosome 1 ALB
nucleoplasm 3 ALOX5, GTPBP4, HIF3A
Cell membrane 5 ACVRL1, C5AR1, CYSLTR2, FPR1, LTB4R
Cytoplasmic side 1 ALDH3A2
Multi-pass membrane protein 4 C5AR1, CYSLTR2, FPR1, LTB4R
Synapse 1 AKR1A1
cell surface 2 ACVRL1, CD40
Golgi apparatus 1 ALB
neuronal cell body 2 ACVRL1, CD40
Cytoplasm, cytosol 2 AKR1A1, ALOX5
plasma membrane 11 ACVRL1, C5AR1, CD40, CD83, CSF2, CYSLTR2, FPR1, HIF3A, IGHE, LTB4R, PRKCQ
Membrane 6 ACVRL1, ALDH3A2, CD40, CD83, FPR1, GTPBP4
apical plasma membrane 1 AKR1A1
basolateral plasma membrane 1 C5AR1
extracellular exosome 4 AKR1A1, ALB, CD40, EPHX2
endoplasmic reticulum 1 ALB
extracellular space 9 AKR1A1, ALB, ALOX5, CD40, CSF2, CXCL8, IGHE, IL10, IL4
perinuclear region of cytoplasm 2 ALOX5, GTPBP4
mitochondrion 1 HIF3A
protein-containing complex 1 ALB
intracellular membrane-bounded organelle 3 ALDH3A2, CD40, CSF2
Microsome membrane 1 ALDH3A2
Single-pass type I membrane protein 3 ACVRL1, CD40, IGHE
Secreted 5 ALB, CSF2, CXCL8, IL10, IL4
extracellular region 7 ALB, ALOX5, CSF2, CXCL8, IGHE, IL10, IL4
Single-pass membrane protein 1 ALDH3A2
anchoring junction 1 ALB
centriolar satellite 1 PRKCQ
Nucleus membrane 1 ALOX5
nuclear membrane 2 ALOX5, GTPBP4
CD40 receptor complex 1 CD40
external side of plasma membrane 2 CD40, CD83
varicosity 1 CD40
cytoplasmic vesicle 1 C5AR1
nucleolus 1 GTPBP4
apical part of cell 1 C5AR1
Apical cell membrane 1 AKR1A1
Cytoplasm, perinuclear region 1 ALOX5
Peroxisome 2 ALDH3A2, EPHX2
peroxisomal matrix 1 EPHX2
peroxisomal membrane 1 ALDH3A2
nuclear speck 1 HIF3A
ciliary basal body 1 ALB
chromatin 1 HIF3A
IgE immunoglobulin complex 1 IGHE
centriole 1 ALB
Nucleus, nucleolus 1 GTPBP4
spindle pole 1 ALB
blood microparticle 1 ALB
[Isoform 2]: Cell membrane 1 IGHE
nuclear envelope 1 ALOX5
Nucleus envelope 1 ALOX5
Nucleus speckle 1 HIF3A
ficolin-1-rich granule lumen 1 ALOX5
secretory granule lumen 1 ALOX5
secretory granule membrane 2 C5AR1, FPR1
endoplasmic reticulum lumen 1 ALB
nuclear matrix 1 ALOX5
platelet alpha granule lumen 1 ALB
azurophil granule membrane 1 FPR1
immunological synapse 1 PRKCQ
aggresome 1 PRKCQ
Nucleus matrix 1 ALOX5
nuclear envelope lumen 1 ALOX5
ficolin-1-rich granule membrane 1 FPR1
granulocyte macrophage colony-stimulating factor receptor complex 1 CSF2
[Isoform 3]: Cell membrane 1 IGHE
[Isoform 1]: Secreted 1 IGHE
IgE B cell receptor complex 1 IGHE
immunoglobulin complex, circulating 1 IGHE
Nucleus intermembrane space 1 ALOX5
BMP receptor complex 1 ACVRL1
ciliary transition fiber 1 ALB


文献列表

  • M A Willemsen, J J Rotteveel, J G de Jong, R J Wanders, L IJlst, G F Hoffmann, E Mayatepek. Defective metabolism of leukotriene B4 in the Sjögren-Larsson syndrome. Journal of the neurological sciences. 2001 Jan; 183(1):61-7. doi: 10.1016/s0022-510x(00)00474-3. [PMID: 11166796]
  • J P Merab, S J Feinmark, P J Cannon. Synthesis of leukotrienes C4, D4, E4 and 20-carboxy-B4 by the isolated perfused kidney. Advances in prostaglandin, thromboxane, and leukotriene research. 1989; 19(?):221-4. doi: NULL. [PMID: 2546385]