hydroxypyruvic acid (BioDeep_00001868161)

Main id: BioDeep_00000004388

 

PANOMIX_OTCML-2023


代谢物信息卡片


3-Hydroxypyruvic acid

化学式: C3H4O4 (104.01095839999999)
中文名称: β-羟基丙酮酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C(=O)C(=O)O)O
InChI: InChI=1S/C3H4O4/c4-1-2(5)3(6)7/h4H,1H2,(H,6,7)

描述信息

A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.
Hydroxypyruvic acid (β-Hydroxypyruvic acid) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

同义名列表

3 个代谢物同义名

3-Hydroxypyruvic acid; hydroxypyruvic acid; β-Hydroxypyruvic acid



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Anne Jahn, Maike Petersen. Hydroxy(phenyl)pyruvic acid reductase in Actaea racemosa L.: a putative enzyme in cimicifugic and fukinolic acid biosynthesis. Planta. 2024 Mar; 259(5):102. doi: 10.1007/s00425-024-04382-6. [PMID: 38549005]
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  • Adam D Lietzan, Martin St Maurice. Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs. Biochemical and biophysical research communications. 2013 Nov; 441(2):377-82. doi: 10.1016/j.bbrc.2013.10.066. [PMID: 24157795]
  • Markus Niessen, Katrin Krause, Ina Horst, Norma Staebler, Stephanie Klaus, Stefanie Gaertner, Rashad Kebeish, Wagner L Araujo, Alisdair R Fernie, Christoph Peterhansel. Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice. Journal of experimental botany. 2012 Apr; 63(7):2705-16. doi: 10.1093/jxb/err453. [PMID: 22268146]
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  • Verena Janiak, Maike Petersen, Matthias Zentgraf, Gerhard Klebe, Andreas Heine. Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth. Acta crystallographica. Section D, Biological crystallography. 2010 May; 66(Pt 5):593-603. doi: 10.1107/s0907444910006360. [PMID: 20445235]
  • Ralph Kissen, Per Winge, Diem Hong Thi Tran, Tommy S Jørstad, Trond R Størseth, Tone Christensen, Atle M Bones. Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. BMC genomics. 2010 Mar; 11(?):190. doi: 10.1186/1471-2164-11-190. [PMID: 20307264]
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  • Jianqiang Zhang, Ying Zhang, Ning Li, Zhihong Liu, Changming Xiong, Xinhai Ni, Yaoli Pu, Rutai Hui, Jianguo He, Jielin Pu. Potential diagnostic biomarkers in serum of idiopathic pulmonary arterial hypertension. Respiratory medicine. 2009 Dec; 103(12):1801-6. doi: 10.1016/j.rmed.2009.07.017. [PMID: 19703762]
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  • Björn C Willige, Michael Kutzer, Felix Tebartz, Dorothea Bartels. Subcellular localization and enzymatic properties of differentially expressed transketolase genes isolated from the desiccation tolerant resurrection plant Craterostigma plantagineum. Planta. 2009 Feb; 229(3):659-66. doi: 10.1007/s00425-008-0863-5. [PMID: 19052774]
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