Oxytocin (BioDeep_00001867847)
Main id: BioDeep_00000004477
代谢物信息卡片
Oxytocin acetate salt
化学式: C43H66N12O12S2 (1006.4364356000001)
中文名称: 缩宫素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCCC3C(=O)NC(CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
InChI: InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1
描述信息
H - Systemic hormonal preparations, excl. sex hormones and insulins > H01 - Pituitary and hypothalamic hormones and analogues > H01B - Posterior pituitary lobe hormones > H01BB - Oxytocin and analogues
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C2348 - Pituitary Agent
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D012102 - Reproductive Control Agents > D010120 - Oxytocics
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma[1][2].
同义名列表
4 个代谢物同义名
Oxytocin acetate salt; Oxytocin; α-Hypophamine; Oxytocic hormone
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:7872
- KEGG: C00746
- KEGGdrug: D00089
- PubChem: 439302
- ChEMBL: CHEMBL395429
- MeSH: Oxytocin
- CAS: 50-56-6
- PubChem: 4008
- 3DMET: B01323
- NIKKAJI: J1.360I
- medchemexpress: HY-17571
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 126763 - Oxystelma esculentum: 10.1016/0031-9422(88)80146-8
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Su-Ting Jiang, Shu-Ying Lian, Yao-Huan Sun, Mei-Bo Pan, Bin Wang, Hui Wang, Jun Hua, Yi-Chen Wang, Qiu-Ling Wang, Yin-Feng Dong. The oxytocin receptor is essential for the protective effect of pair housing on post-stroke depression in mice.
Experimental gerontology.
2024 Jun; 190(?):112432. doi:
10.1016/j.exger.2024.112432. [PMID: 38614224] - Antonina I Frolova, Kevin K Prifti, Nandini Raghuraman, Ebony B Carter, Sarah K England, Molly J Stout. Association between Maternal Serum Lipids and Intrapartum Oxytocin Requirements during Labor Induction and Augmentation.
American journal of perinatology.
2024 May; 41(S 01):e1015-e1022. doi:
10.1055/a-1979-8577. [PMID: 36384236] - Gisele Almeida Lopes, Thais Trevisan Teixeira, Nathalie Leister, Maria Luiza Riesco. Methods of induction and augmentation of labor in a freestanding birth center: a cross-sectional study.
Revista da Escola de Enfermagem da U S P.
2024; 57(?):e20230158. doi:
10.1590/1980-220x-reeusp-2023-0158en. [PMID: 38324551] - Yuko Maejima, Shoko Yokota, Megumi Yamachi, Shingen Misaka, Tomoyuki Ono, Hiroaki Oizumi, Keita Mizuno, Shizu Hidema, Katsuhiko Nishimori, Masato Aoyama, Heidi de Wet, Kenju Shimomura. Traditional Japanese medicine Kamikihito ameliorates sucrose preference, chronic inflammation and obesity induced by a high fat diet in middle-aged mice.
Frontiers in endocrinology.
2024; 15(?):1387964. doi:
10.3389/fendo.2024.1387964. [PMID: 38742193] - Erwei Li, Luhong Wang, Daqing Wang, Jingyi Chi, Zeran Lin, Gordon I Smith, Samuel Klein, Paul Cohen, Evan D Rosen. Control of lipolysis by a population of oxytocinergic sympathetic neurons.
Nature.
2024 Jan; 625(7993):175-180. doi:
10.1038/s41586-023-06830-x. [PMID: 38093006] - Liang Wu, Ying Yang, Min Lin, Haiqing Wang, Luqian Li, Haixia Wu, Xue Wang, Ming Yan. Unraveling the anti-primary dysmenorrhea mechanism of Ainsliaea fragrans Champ. extract by the integrative approach of network pharmacology and experimental verification.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155213. doi:
10.1016/j.phymed.2023.155213. [PMID: 37980805] - Sayah Ongsricharoenbhorn, Pakanit Kupittayanant, Kanjana Thumanu, Griangsak Eumkeb, Suthida Chanlun, Pittaya Papirom, Susan Wray, Sajeera Kupittayanant. Effects of Heliotropium indicum L. on Uterine Involution and Its Underlying Mechanisms: an in vivo and in vitro Study.
Chinese journal of integrative medicine.
2023 Nov; 29(11):980-988. doi:
10.1007/s11655-023-3742-9. [PMID: 37608039] - Liu-Jun Wu, Yan Chen, Zi-Wei Lin, Chen Sun, Liang Xiong, Xiao-Fang Xie, Cheng Peng. [Therapeutic effect of Leonuri Herba aqueous decoction on primary dysmenorrhea in rats and its metabolomic analysis].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2023 Nov; 48(22):6093-6106. doi:
10.19540/j.cnki.cjcmm.20230803.401. [PMID: 38114217] - Hilal Korkmaz, Canan Dura Deveci, Yusuf Üstün, Bilge Pehlivanoğlu. Comparison of plasma oxytocin level in women with natural and surgical menopause.
Endocrine.
2023 10; 82(1):209-214. doi:
10.1007/s12020-023-03453-0. [PMID: 37477780] - Alexander V Sirotkin, Adam Tarko, Zuzana Fabova, Igor Valocky, Saleh Alwasel, Jan Kotwica, Abdel Halim Harrath. Can flaxseed, chia or puncture vine affect mare ovarian cell functions and prevent the toxic effect of the environmental contaminant toluene?.
Theriogenology.
2023 Sep; 208(?):178-184. doi:
10.1016/j.theriogenology.2023.06.018. [PMID: 37354861] - Feiye Wu, Jing Zhu, Yang Wan, Subinuer Kurexi, Jia Zhou, Ke Wang, Tongyu Chen. Electroacupuncture Ameliorates Hypothalamic‒Pituitary‒Adrenal Axis Dysfunction Induced by Surgical Trauma in Mice Through the Hypothalamic Oxytocin System.
Neurochemical research.
2023 Jul; ?(?):. doi:
10.1007/s11064-023-03984-y. [PMID: 37436613] - Yi Zhang, Yangyang Zhu, Jinghui Wang, Li Jin, Mingwei Guo, Liwei Chen, Lina Zhang, Yangyang Li, Baocheng Wan, Rong Zhang, Weiping Jia, Cheng Hu. Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany).
2023 06; 10(16):e2204824. doi:
10.1002/advs.202204824. [PMID: 37060105] - Fu-Guang Wang, Yi Sun, Juan Cao, Xu-Ri Shen, Fu-Wang Liu, Shuang-Shuang Song, Xue-Qin Hou, Lei Yin. Effects of Danggui-Shaoyao-San on central neuroendocrine and pharmacokinetics in female ovariectomized rats.
Journal of ethnopharmacology.
2023 May; ?(?):116609. doi:
10.1016/j.jep.2023.116609. [PMID: 37150422] - A V Sirotkin, A Tarko, J Kotwica, M Mlyncek, S Alwasel, S Nitrayova, A H Harrath. Three medicinal plants affecting human ovarian cell viability, hormone release, and response to environmental contaminant toluene.
Physiological research.
2023 Apr; 72(2):259-268. doi:
. [PMID: 37159859] - Yanqu Zhou, Mei Liu, Xiuxiu Liu, Rulan Jiang, Yunan He, Qian Yao, Hong Chen, Chunmei Fu. Rapid and sensitive fluorescence determination of oxytocin using nitrogen-doped carbon dots as fluorophores.
Journal of pharmaceutical and biomedical analysis.
2023 Mar; 229(?):115344. doi:
10.1016/j.jpba.2023.115344. [PMID: 36966622] - Alexander V Sirotkin, Martina Macejková, Adam Tarko, Zuzana Fabova, Saleh Alwasel, Jan Kotwica, Abdel Halim Harrath. Ginkgo, fennel, and flaxseed can affect hormone release by porcine ovarian cells and modulate the effect of toluene.
Reproductive biology.
2023 Mar; 23(1):100736. doi:
10.1016/j.repbio.2023.100736. [PMID: 36773449] - D E Olazábal, N Pillay, N Sandberg, K-J Hartman. Description and comparison of brain distribution of oxytocin receptors in Rhabdomys pumillio and Rhabdomys dilectus.
General and comparative endocrinology.
2023 Jan; 335(?):114224. doi:
10.1016/j.ygcen.2023.114224. [PMID: 36702289] - C C Cingi, D Eroglu. Efficacy of nasal stimulants on interpersonal communication - a narrative review.
European review for medical and pharmacological sciences.
2022 12; 26(2 Suppl):99-102. doi:
10.26355/eurrev_202212_30492. [PMID: 36524917] - Nara Lins Meira Quintão, Jaqueline Pavesi Reis, Larissa Benvenutti, Roberta Nunes, Fernanda Capitanio Goldoni, Manuela Somensi Cozer, Priscila de Souza, Rita de Cássia Melo Vilhena de Andrade Fonseca da Silva, Jessica Melato, Carlos Rafael Vaz, Juliana Cristina Pereira Whitaker, Flavia Werner Jesuíno, Mariana Couto Costa, Maria Verônica Dávila Pastor, Angela Malheiros, Christiane Meyre-Silva, José Roberto Santin. Involvement of a neutrophil-mast cell axis in the effects of Piper malacophyllum (C. PESL) C. DC extract and its isolated compounds in a mouse model of dysmenorrhoea.
Inflammopharmacology.
2022 Dec; 30(6):2489-2504. doi:
10.1007/s10787-022-01032-9. [PMID: 35867292] - Xiaoqin Liu, Xianglong Meng, Xiaojuan Su, Kele Ren, Chenxu Ning, Xiaoming Qi, Shuosheng Zhang. The mechanism of ginger and its processed products in the treatment of estradiol valerate coupled with oxytocin-induced dysmenorrhea in mice via regulating the TRP ion channel-mediated ERK1/2/NF-κB signaling pathway.
Food & function.
2022 Oct; 13(21):11236-11248. doi:
10.1039/d2fo01845d. [PMID: 36222424] - Adriano Winterton, Francesco Bettella, Dani Beck, Tiril P Gurholt, Nils Eiel Steen, Linn Rødevand, Lars T Westlye, Ole A Andreassen, Daniel S Quintana. The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health.
Psychoneuroendocrinology.
2022 10; 144(?):105875. doi:
10.1016/j.psyneuen.2022.105875. [PMID: 35939863] - Terigele Bao, Lan Feng, Sungbo Cho, Hongzhen Yu, Wenjie Jin, Lili Dai, Junqing Zhang, Laxinamujila Bai, Minghai Fu, Yongsheng Chen. RNA-Seq Reveals Protective Mechanisms of Mongolian Medicine Molor-Dabos-4 on Acute Indomethacin-Induced Gastric Ulcers in Rats.
Genes.
2022 Sep; 13(10):. doi:
10.3390/genes13101740. [PMID: 36292625] - Mitchell Ty Ringuet, John Barton Furness, Sebastian George Barton Furness. G protein-coupled receptor interactions and modification of signalling involving the ghrelin receptor, GHSR1a.
Journal of neuroendocrinology.
2022 09; 34(9):e13077. doi:
10.1111/jne.13077. [PMID: 34931385] - Boya Huang, Binhuang Sun, Rui Yang, Shihao Liang, Xinrui Li, Yi Guo, Qian Meng, Yaling Fu, Wenshuya Li, Penghui Zhao, Miao Gong, Yun Shi, Li Song, Sheng Wang, Fang Yuan, Haishui Shi. Long-lasting effects of postweaning sleep deprivation on cognitive function and social behaviors in adult mice.
Neuropharmacology.
2022 09; 215(?):109164. doi:
10.1016/j.neuropharm.2022.109164. [PMID: 35716724] - Jamshid Faraji, Hamid Lotfi, Alireza Moharrerie, S Yaghoob Jafari, Nasrin Soltanpour, Rosa Tamannaiee, Kameran Marjani, Shabnam Roudaki, Farhad Naseri, Reza Moeeini, Gerlinde A S Metz. Regional Differences in BDNF Expression and Behavior as a Function of Sex and Enrichment Type: Oxytocin Matters.
Cerebral cortex (New York, N.Y. : 1991).
2022 07; 32(14):2985-2999. doi:
10.1093/cercor/bhab395. [PMID: 35059698] - Hakan Sahin, Oguz Yucel, Serkan Emik, Gozde Erkanli Senturk. Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage.
ACS chemical neuroscience.
2022 07; 13(13):1923-1937. doi:
10.1021/acschemneuro.2c00124. [PMID: 35713692] - Sarah J Baracz, Katherine J Robinson, Amanda L Wright, Anita J Turner, Iain S McGregor, Jennifer L Cornish, Nicholas A Everett. Oxytocin as an adolescent treatment for methamphetamine addiction after early life stress in male and female rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2022 07; 47(8):1561-1573. doi:
10.1038/s41386-022-01336-y. [PMID: 35581382] - Angela C Incollingo Rodriguez, Laura Smith, Rebeca Harris, Benjamin C Nephew, Hudson P Santos, Chris Murgatroyd. Oxytocin modulates sensitivity to acculturation and discrimination stress in pregnancy.
Psychoneuroendocrinology.
2022 07; 141(?):105769. doi:
10.1016/j.psyneuen.2022.105769. [PMID: 35462200] - Katja Hoehne, Pascal Vrtička, Veronika Engert, Tania Singer. Plasma oxytocin is modulated by mental training, but does not mediate its stress-buffering effect.
Psychoneuroendocrinology.
2022 07; 141(?):105734. doi:
10.1016/j.psyneuen.2022.105734. [PMID: 35367715] - Benjamin A Tabak, David Rosenfield, Cecile S Sunahara, Talha Alvi, Angela Szeto, Armando J Mendez. Social anxiety is associated with greater peripheral oxytocin reactivity to psychosocial stress.
Psychoneuroendocrinology.
2022 06; 140(?):105712. doi:
10.1016/j.psyneuen.2022.105712. [PMID: 35306471] - Juan Liu, Rui Feng, Ou Dai, Hong Ni, Lu-Si Liu, Hong-Zhen Shu, Yan Lu, Cheng Peng, Liang Xiong. Isoindolines and phthalides from the rhizomes of Ligusticum chuanxiong and their relaxant effects on the uterine smooth muscle.
Phytochemistry.
2022 Jun; 198(?):113159. doi:
10.1016/j.phytochem.2022.113159. [PMID: 35283167] - Marie N N Hellem, Rachel Y Cheong, Simone Tonetto, Tua Vinther-Jensen, Rebecca K Hendel, Ida U Larsen, Troels T Nielsen, Lena E Hjermind, Asmus Vogel, Esben Budtz-Jørgensen, Åsa Petersén, Jørgen E Nielsen. Decreased CSF oxytocin relates to measures of social cognitive impairment in Huntington's disease patients.
Parkinsonism & related disorders.
2022 06; 99(?):23-29. doi:
10.1016/j.parkreldis.2022.05.003. [PMID: 35580426] - Saeed Naghibi, Ali Barzegari, Mohammad Shariatzadeh, Maryam Vatandoust, Mandana Ahmadi, Elham Mahdinia, Fatemeh Neghabi, Amir Rajabpour, Atikeh Sadat Aleahmad, Forough Sadat Balaghati, Samira Sadat Naserimanesh, Mina Saeedipour, Omid Sadeghi, Fatemeh Yeganeh, Ali-Akbar Salari. Voluntary physical activity increases maternal care and reduces anxiety- and depression-related behaviours during the postpartum period in mice.
Brain research.
2022 06; 1784(?):147880. doi:
10.1016/j.brainres.2022.147880. [PMID: 35288124] - A J Conley, T Berger, R Arias Del Razo, R F Cotterman, E Sahagún, L R Goetze, S Jacob, T A R Weinstein, M E Dufek, S P Mendoza, K L Bales. The onset of puberty in colony-housed male and female titi monkeys (Plecturocebus cupreus): Possible effects of oxytocin treatment during peri-adolescent development.
Hormones and behavior.
2022 Jun; 142(?):105157. doi:
10.1016/j.yhbeh.2022.105157. [PMID: 35338890] - Fang Hong, Guiyan He, Manqi Zhang, Boyang Yu, Chengzhi Chai. The Establishment of a Mouse Model of Recurrent Primary Dysmenorrhea.
International journal of molecular sciences.
2022 May; 23(11):. doi:
10.3390/ijms23116128. [PMID: 35682815] - Ye-Ji Kim, Jei Ha Lee, Seung-Hyun Jung, Ki Hyun Kim, Chang-Hoon Choi, Seonmi Jo, Dong Ho Woo. An Octopus-Derived Peptide with Antidiuretic Activity in Rats.
Marine drugs.
2022 May; 20(5):. doi:
10.3390/md20050328. [PMID: 35621979] - Luís Fernando Gadioli Santos, Fernanda Fernandes-Breitenbach, Rafael Augusto Santos Silva, Damáris Raíssa Santos, Melise Jacon Peres-Ueno, Edilson Ervolino, Antonio Hernandes Chaves-Neto, Rita Cássia Menegati Dornelles. The action of oxytocin on the bone of senescent female rats.
Life sciences.
2022 May; 297(?):120484. doi:
10.1016/j.lfs.2022.120484. [PMID: 35301015] - Martin Köhne, Christin Unruh, Denny Böttcher, Anna Tönissen, Reiner Ulrich, Harald Sieme. Evaluation of an ex vivo model of the blood-perfused equine uterus.
Theriogenology.
2022 May; 184(?):82-91. doi:
10.1016/j.theriogenology.2022.02.026. [PMID: 35286912] - Michael J Spilka, William R Keller, Robert W Buchanan, James M Gold, James I Koenig, Gregory P Strauss. Endogenous oxytocin levels are associated with facial emotion recognition accuracy but not gaze behavior in individuals with schizophrenia.
Acta psychiatrica Scandinavica.
2022 05; 145(5):494-506. doi:
10.1111/acps.13421. [PMID: 35243618] - Annabel J Cohen, Inga D Neumann. A model for the social neuroscience of music production begins on a dubious note: Commentary on Greenberg et al. (2021).
The American psychologist.
2022 May; 77(4):616-618. doi:
10.1037/amp0000973. [PMID: 35708943] - John Flanagan, Andreas Chatzittofis, Adrian Desai E Boström, Jonas Hallberg, Katarina Görts Öberg, Stefan Arver, Jussi Jokinen. High Plasma Oxytocin Levels in Men With Hypersexual Disorder.
The Journal of clinical endocrinology and metabolism.
2022 04; 107(5):e1816-e1822. doi:
10.1210/clinem/dgac015. [PMID: 35108393] - Akiko Seguchi, Kazutaka Mogi, Ei-Ichi Izawa. Measurement of urinary mesotocin in large-billed crows by enzyme-linked immunosorbent assay.
The Journal of veterinary medical science.
2022 Apr; 84(4):520-524. doi:
10.1292/jvms.21-0635. [PMID: 35153252] - Sina Zimmermann, Bettina C Thomas, Johannes Krisam, Ronald Limprecht, Christina Klose, Manuel Stenger, Madeleine Pourbaix, Marcel Ries, Sabine Vollstaedt-Klein, Anne Koopmann, Bernd Lenz, Falk Kiefer, Patrick Bach. ON-ICE trial: Investigation of the combined effects of oxytocin and naltrexone on stress-induced and alcohol cue-induced craving in alcohol use disorder-Study protocol of a phase II randomised double-blind placebo-controlled parallel-group trial.
BMJ open.
2022 04; 12(4):e059672. doi:
10.1136/bmjopen-2021-059672. [PMID: 35410938] - Akiko Nakashima, Noriyuki Nakashima, Kie Nakashima, Makoto Takano. Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice.
Molecular brain.
2022 04; 15(1):29. doi:
10.1186/s13041-022-00917-8. [PMID: 35379313] - Iris C Reiner, Gerald Gimpl, Manfred E Beutel, Marian J Bakermans-Kranenburg, Helge Frieling. OXTR-Related Markers in Clinical Depression: a Longitudinal Case-Control Psychotherapy Study.
Journal of molecular neuroscience : MN.
2022 Apr; 72(4):695-707. doi:
10.1007/s12031-021-01930-7. [PMID: 34822109] - Gillian England-Mason, Harriet L MacMillan, Leslie Atkinson, Meir Steiner, Andrea Gonzalez. Emotion regulation moderates between maternal adverse childhood experiences (ACEs) and oxytocin response.
Archives of women's mental health.
2022 04; 25(2):421-430. doi:
10.1007/s00737-021-01194-5. [PMID: 34751819] - Ariel Kor, Amir Djalovski, Marc N Potenza, Orna Zagoory-Sharon, Ruth Feldman. Alterations in oxytocin and vasopressin in men with problematic pornography use: The role of empathy.
Journal of behavioral addictions.
2022 Mar; 11(1):116-127. doi:
10.1556/2006.2021.00089. [PMID: 35040806] - L Veiga, E Carolino, I Santos, C Veríssimo, A Almeida, A Grilo, M Brito, M C Santos. Depressive symptomatology, temperament and oxytocin serum levels in a sample of healthy female university students.
BMC psychology.
2022 Feb; 10(1):36. doi:
10.1186/s40359-022-00744-5. [PMID: 35193693] - Phuoc-Tan Diep, Véronique de Kok. Could oxytocin reduce autoimmune disease in COVID-19?.
Autoimmunity reviews.
2022 Feb; 21(2):102994. doi:
10.1016/j.autrev.2021.102994. [PMID: 34798315] - Daniel B Andersen, Jens J Holst. Peptides in the regulation of glucagon secretion.
Peptides.
2022 02; 148(?):170683. doi:
10.1016/j.peptides.2021.170683. [PMID: 34748791] - Daniela Baptista-de-Souza, Lígia Renata Rodrigues Tavares, Lucas Canto-de-Souza, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souza. Behavioral, hormonal, and neural alterations induced by social contagion for pain in mice.
Neuropharmacology.
2022 02; 203(?):108878. doi:
10.1016/j.neuropharm.2021.108878. [PMID: 34774550] - Ana Macchia, Paul Theo Zebhauser, Stephanie Salcedo, Bethany Burum, Edward Gold, Miguel Alonso-Alonso, Alvaro Pascual-Leone, Daniel Gilbert, Anna-Katharine Brem. Divergent effects of oxytocin on 'mind-reading' in healthy males.
Cognitive, affective & behavioral neuroscience.
2022 02; 22(1):112-122. doi:
10.3758/s13415-021-00936-3. [PMID: 34519018] - Matthias A Reinhard, Frank Padberg, Julia Dewald-Kaufmann, Torsten Wüstenberg, Stephan Goerigk, Barbara B Barton, Adima Zülch, Lisa Brandl, Hannah Windmüller, Fabiana Fernandes, Andre R Brunoni, Richard Musil, Andrea Jobst. Sequential Social Exclusion in a Novel Cyberball Paradigm Leads to Reduced Behavioral Repair and Plasma Oxytocin in Borderline Personality Disorder.
Journal of personality disorders.
2022 Feb; 36(1):99-115. doi:
10.1521/pedi_2021_35_532. [PMID: 34427490] - Michael J Hylin, W Tang Watanasriyakul, Natalee Hite, Neal McNeal, Angela J Grippo. Morphological changes in the basolateral amygdala and behavioral disruptions associated with social isolation.
Behavioural brain research.
2022 01; 416(?):113572. doi:
10.1016/j.bbr.2021.113572. [PMID: 34499940] - Sheng Wang, Peize Wu, Ming Li, Ting Huang, Naijie Shi, Liuxing Feng, Hongmei Li. Mass balance method for SI-traceable purity assignment of synthetic oxytocin.
Journal of pharmaceutical and biomedical analysis.
2022 Jan; 207(?):114401. doi:
10.1016/j.jpba.2021.114401. [PMID: 34656934] - Stephani C Wang, Fengmin Zhang, Hui Zhu, Haipeng Yang, Yang Liu, Ping Wang, Vladimir Parpura, Yu-Feng Wang. Potential of Endogenous Oxytocin in Endocrine Treatment and Prevention of COVID-19.
Frontiers in endocrinology.
2022; 13(?):799521. doi:
10.3389/fendo.2022.799521. [PMID: 35592777] - Phuoc-Tan Diep. TRPV1, Nrf2, and COVID-19: Could Oxytocin Have a Beneficial Role to Play?.
International archives of allergy and immunology.
2022; 183(2):246-247. doi:
10.1159/000521246. [PMID: 34979508] - Yousuke Tsuneoka, Chihiro Yoshihara, Ryuko Ohnishi, Sachine Yoshida, Eri Miyazawa, Masanobu Yamada, Kazuhiko Horiguchi, W Scott Young, Katsuhiko Nishimori, Tadafumi Kato, Kumi O Kuroda. Oxytocin Facilitates Allomaternal Behavior under Stress in Laboratory Mice.
eNeuro.
2022 Jan; 9(1):. doi:
10.1523/eneuro.0405-21.2022. [PMID: 35017259] - Zainab Al-Ali, Akeel Abed Yasseen, Arafat Al-Dujailli, Ahmed Jafar Al-Karaqully, Katherine Ann McAllister, Alaa Salah Jumaah. The oxytocin receptor gene polymorphism rs2268491 and serum oxytocin alterations are indicative of autism spectrum disorder: A case-control paediatric study in Iraq with personalized medicine implications.
PloS one.
2022; 17(3):e0265217. doi:
10.1371/journal.pone.0265217. [PMID: 35316293] - Akiko Harauma, Shunichi Nakamura, Natsuko Wakinaka, Kazutaka Mogi, Toru Moriguchi. Influence of ω3 fatty acids on maternal behavior and brain oxytocin in the murine perinatal period.
Prostaglandins, leukotrienes, and essential fatty acids.
2022 01; 176(?):102386. doi:
10.1016/j.plefa.2021.102386. [PMID: 34896909] - Asmaa Elnagar, Khalifa El-Dawy, Hussein I El-Belbasi, Ibrahim F Rehan, Hamdy Embark, Zeinab Al-Amgad, Obeid Shanab, Elsayed Mickdam, Gaber E Batiha, Salman Alamery, Samer S Fouad, Simona Cavalu, Mohammed Youssef. Ameliorative Effect of Oxytocin on FBN1 and PEPCK Gene Expression, and Behavioral Patterns in Rats' Obesity-Induced Diabetes.
Frontiers in public health.
2022; 10(?):777129. doi:
10.3389/fpubh.2022.777129. [PMID: 35462799] - Ricardo Mondragón-Ceballos, Génesis Chantal Hernández-Vázquez, Susana Rojas-Maya, Mónica Dafne García-Granados, Jaqueline Lugo-Ferrer, Leonor Estela Hernández-López. The effects of female-male friendships on male postcopulatory levels of oxytocin and vasopressin, and sperm parameters in Macacaarctoides.
Theriogenology.
2022 Jan; 177(?):63-72. doi:
10.1016/j.theriogenology.2021.09.022. [PMID: 34666204] - J Fusi, M C Veronesi. Canine parturition: what is known about the hormonal setting?.
Domestic animal endocrinology.
2022 01; 78(?):106687. doi:
10.1016/j.domaniend.2021.106687. [PMID: 34653927] - Katharina Gryksa, Inga D Neumann. Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system.
Psychoneuroendocrinology.
2022 01; 135(?):105601. doi:
10.1016/j.psyneuen.2021.105601. [PMID: 34837776] - Kazunori Sasaki, Farhana Ferdousi, Satoshi Fukumitsu, Hidetoshi Kuwata, Hiroko Isoda. Antidepressant- and anxiolytic-like activities of Rosmarinus officinalis extract in rodent models: Involvement of oxytocinergic system.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Dec; 144(?):112291. doi:
10.1016/j.biopha.2021.112291. [PMID: 34653760] - Stanislav M Cherepanov, Maria Gerasimenko, Teruko Yuhi, Anna Shabalova, Hong Zhu, Shigeru Yokoyama, Alla B Salmina, Shei-Ichi Munesue, Ai Harashima, Yasuhiko Yamamoto, Haruhiro Higashida. An improved sample extraction method reveals that plasma receptor for advanced glycation end-products (RAGE) modulates circulating free oxytocin in mice.
Peptides.
2021 12; 146(?):170649. doi:
10.1016/j.peptides.2021.170649. [PMID: 34543678] - Yazmín Hernández-Díaz, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, María Lilia López-Narváez, Alma Delia Genis-Mendoza, Rosa Giannina Castillo-Avila, Miguel Ángel Ramos-Méndez, Isela Esther Juárez-Rojop. Oxytocin levels in individuals with schizophrenia are high in cerebrospinal fluid but low in serum: A systematic review and meta-analysis : Oxytocin and Schizophrenia.
Metabolic brain disease.
2021 12; 36(8):2415-2424. doi:
10.1007/s11011-021-00836-y. [PMID: 34495462] - Ícaro Araújo de Sousa, Gabriel Medina Sobreira de Meneses, José Victor Miranda Cardoso, Pablo Queiroz Lopes, Joubert Aires de Sousa, Suzana Maria Pereira Galvão Cavalcanti, Paulo Marques da Silva Cavalcanti, Francisco Chagas Filho. Inhibitory effect of Pyr6 (an Orai channel blocker) on agonist-induced contractions in rat uterus.
The journal of obstetrics and gynaecology research.
2021 Dec; 47(12):4306-4318. doi:
10.1111/jog.15034. [PMID: 34571573] - Betül Sözeri, Şengül Çağlayan, Vildan Atasayan, Kadir Ulu, Taner Coşkuner, Özge Pelin Akbay, Canan Hasbal Akkuş, Gürkan Atay, Enes Salı, Mehmet Karacan, Taliha Öner, Seher Erdoğan, Ferhat Demir. The clinical course and short-term health outcomes of multisystem inflammatory syndrome in children in the single pediatric rheumatology center.
Postgraduate medicine.
2021 Nov; 133(8):994-1000. doi:
10.1080/00325481.2021.1987732. [PMID: 34605352] - I H Sever, B Ozkul, D Erisik Tanriover, O Ozkul, C S Elgormus, S G Gur, I Sogut, Y Uyanikgil, E O Cetin, O Erbas. Protective effect of oxytocin through its anti-inflammatory and antioxidant role in a model of sepsis-induced acute lung injury: Demonstrated by CT and histological findings.
Experimental lung research.
2021 11; 47(9):426-435. doi:
10.1080/01902148.2021.1992808. [PMID: 34665057] - Duncan J MacGregor. Phasic spiking in vasopressin neurons: How and Why.
Journal of neuroendocrinology.
2021 11; 33(11):e13042. doi:
10.1111/jne.13042. [PMID: 34748249] - Freja Grønbæk-Thorsen, Camilla Jensen, Jesper Østergaard, Laura Hyrup Møller, Bente Gammelgaard. Comparison of external calibration and isotope dilution LC-ICP-MS/MS for quantitation of oxytocin and its selenium analogue in human plasma.
Analytical and bioanalytical chemistry.
2021 Nov; 413(26):6479-6488. doi:
10.1007/s00216-021-03611-1. [PMID: 34458946] - Amr S El-Shalofy, Mohamed G Hedia. Exogenous oxytocin administration improves the testicular blood flow in rams.
Andrologia.
2021 Nov; 53(10):e14193. doi:
10.1111/and.14193. [PMID: 34309888] - Kanako Miyano, Yuki Yoshida, Shigeto Hirayama, Hideki Takahashi, Haruka Ono, Yoshiyuki Meguro, Sei Manabe, Akane Komatsu, Miki Nonaka, Takaaki Mizuguchi, Hideaki Fujii, Yoshikazu Higami, Minoru Narita, Yasuhito Uezono. Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not δ-Opioid Receptors in the G Protein Signaling Pathway.
Cells.
2021 10; 10(10):. doi:
10.3390/cells10102651. [PMID: 34685631] - Pablo Giménez-Gómez, Raúl Ballestín, Leticia Gil de Biedma-Elduayen, Rebeca Vidal, Carmen Ferrer-Pérez, Marina D Reguilón, Esther O'Shea, José Miñarro, María Isabel Colado, Marta Rodríguez-Arias. Decreased kynurenine pathway potentiate resilience to social defeat effect on cocaine reward.
Neuropharmacology.
2021 10; 197(?):108753. doi:
10.1016/j.neuropharm.2021.108753. [PMID: 34389399] - Diana N Krause, Karin Warfvinge, Kristian Agmund Haanes, Lars Edvinsson. Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP.
Nature reviews. Neurology.
2021 10; 17(10):621-633. doi:
10.1038/s41582-021-00544-2. [PMID: 34545218] - Lobna A Abdelwahab, Omneya O Galal, Sahar S Abd El-Rahman, Amany I El-Brairy, Mahmoud M Khattab, Aiman S El-Khatib. Targeting the Oxytocin System to Ameliorate Early Life Depressive-Like Behaviors in Maternally-Separated Rats.
Biological & pharmaceutical bulletin.
2021 Oct; 44(10):1445-1457. doi:
10.1248/bpb.b21-00247. [PMID: 34349049] - A S Ducloy-Bouthors, F J Mercier, J M Grouin, F Bayoumeu, J Corouge, A Le Gouez, T Rackelboom, F Broisin, F Vial, A Luzi, O Capronnier, C Huissoud, A Mignon. Early and systematic administration of fibrinogen concentrate in postpartum haemorrhage following vaginal delivery: the FIDEL randomised controlled trial.
BJOG : an international journal of obstetrics and gynaecology.
2021 10; 128(11):1814-1823. doi:
10.1111/1471-0528.16699. [PMID: 33713384] - Gitanjali E Gnanadesikan, Elizabeth A D Hammock, Stacey R Tecot, C Sue Carter, Evan L MacLean. Specificity of plasma oxytocin immunoassays: A comparison of commercial assays and sample preparation techniques using oxytocin knockout and wildtype mice.
Psychoneuroendocrinology.
2021 10; 132(?):105368. doi:
10.1016/j.psyneuen.2021.105368. [PMID: 34364024] - Livia H Morais, Anna V Golubeva, Sophie Casey, Karen A Scott, Ana Paula Ramos Costa, Gerard M Moloney, Timothy G Dinan, John F Cryan. Early-life oxytocin attenuates the social deficits induced by caesarean-section delivery in the mouse.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.
2021 10; 46(11):1958-1968. doi:
10.1038/s41386-021-01040-3. [PMID: 34040156] - Susu Pan, Kaili Yin, Zhiwei Tang, Shuren Wang, Zhuo Chen, Yirong Wang, Hongxia Zhu, Yunyun Han, Mei Liu, Man Jiang, Ningzhi Xu, Guo Zhang. Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice.
eLife.
2021 09; 10(?):. doi:
10.7554/elife.67535. [PMID: 34528509] - Sara E Espinoza, Jessica L Lee, Chen-Pin Wang, Vinutha Ganapathy, Daniel MacCarthy, Chiara Pascucci, Nicolas Musi, Elena Volpi. Intranasal Oxytocin Improves Lean Muscle Mass and Lowers LDL Cholesterol in Older Adults with Sarcopenic Obesity: A Pilot Randomized Controlled Trial.
Journal of the American Medical Directors Association.
2021 09; 22(9):1877-1882.e2. doi:
10.1016/j.jamda.2021.04.015. [PMID: 34029521] - Gönül Çatli, Sezer Acar, Gülten Cingöz, Khayala Rasulova, Ayça Kanat Yarim, Hamide Uzun, Tuncay Küme, Sefa Kızıldağ, Bumin Nuri Dündar, Ayhan Abacı. Oxytocin receptor gene polymorphism and low serum oxytocin level are associated with hyperphagia and obesity in adolescents.
International journal of obesity (2005).
2021 09; 45(9):2064-2073. doi:
10.1038/s41366-021-00876-5. [PMID: 34091593] - Jillian M Rung, Marilyn Horta, Erin M Tammi, Eliany Perez, Marite C Ojeda, Tian Lin, Griffin Harris, Jessie Somerville, Dinia Salmeron, Susan E Beltz, Bhanuprasad Sandesara, David Feifel, Natalie C Ebner. Safety and tolerability of chronic intranasal oxytocin in older men: results from a randomized controlled trial.
Psychopharmacology.
2021 Sep; 238(9):2405-2418. doi:
10.1007/s00213-021-05862-3. [PMID: 33982141] - Manuela Filippa, Maria Grazia Monaci, Carmen Spagnuolo, Paolo Serravalle, Roberta Daniele, Didier Grandjean. Maternal speech decreases pain scores and increases oxytocin levels in preterm infants during painful procedures.
Scientific reports.
2021 08; 11(1):17301. doi:
10.1038/s41598-021-96840-4. [PMID: 34453088] - Stephen J Assinder, Badwi B Boumelhem. Oxytocin stimulates lipolysis, prostaglandin E2 synthesis, and leptin secretion in 3T3-L1 adipocytes.
Molecular and cellular endocrinology.
2021 08; 534(?):111381. doi:
10.1016/j.mce.2021.111381. [PMID: 34216640] - Mana Tsukada, Hideshi Ikemoto, Xiao-Pen Lee, Takashi Takaki, Naoko Tsuchiya, Keita Mizuno, Tatsuki Inoue, Yoshiki Tsunokawa, Takayuki Okumo, Takaaki Matsuyama, Masataka Sunagawa. Kamikihito, a traditional Japanese Kampo medicine, increases the secretion of oxytocin in rats with acute stress.
Journal of ethnopharmacology.
2021 Aug; 276(?):114218. doi:
10.1016/j.jep.2021.114218. [PMID: 34029638] - Véronique Breuil, Marie-Charlotte Trojani, Amri Ez-Zoubir. Oxytocin and Bone: Review and Perspectives.
International journal of molecular sciences.
2021 Aug; 22(16):. doi:
10.3390/ijms22168551. [PMID: 34445256] - Ivaldo Jesus Almeida Belém-Filho, Taíz Francine Silva Brasil, Eduardo Albino Trindade Fortaleza, José Antunes-Rodrigues, Fernando Morgan Aguiar Corrêa. A functional selective effect of oxytocin secreted under restraint stress in rats.
European journal of pharmacology.
2021 Aug; 904(?):174182. doi:
10.1016/j.ejphar.2021.174182. [PMID: 34004212] - Clara O Sailer, Bettina Winzeler, Sandrine A Urwyler, Ingeborg Schnyder, Julie Refardt, Anne Eckert, Nimmy Varghese, Martin Fassnacht, Irina Chifu, Elizabeth A Lawson, Joseph G Verbalis, Wiebke Fenske, Mirjam Christ-Crain. Oxytocin levels in response to pituitary provocation tests in healthy volunteers.
European journal of endocrinology.
2021 Aug; 185(3):355-364. doi:
10.1530/eje-21-0346. [PMID: 34181566] - Alyssa R Morris, Alexandra Turner, Chase H Gilbertson, Geoffrey Corner, Armando J Mendez, Darby E Saxbe. Physical touch during father-infant interactions is associated with paternal oxytocin levels.
Infant behavior & development.
2021 08; 64(?):101613. doi:
10.1016/j.infbeh.2021.101613. [PMID: 34311178] - Giulia Pedretti, Gwendolyn Wirobski, Friederike Range, Sarah Marshall-Pescini. Artificially elevated oxytocin concentrations in pet dogs are associated with higher proximity-maintenance and gazing towards the owners.
Physiology & behavior.
2021 08; 237(?):113451. doi:
10.1016/j.physbeh.2021.113451. [PMID: 33974958] - Arielle R Strzelewicz, Haley A Vecchiarelli, Alejandro N Rondón-Ortiz, Anthony Raneri, Matthew N Hill, Amanda C Kentner. Interactive effects of compounding multidimensional stressors on maternal and male and female rat offspring outcomes.
Hormones and behavior.
2021 08; 134(?):105013. doi:
10.1016/j.yhbeh.2021.105013. [PMID: 34171577] - Marwa Brahmi, Moufida Atigui, Ihmen Hammadi, Jacques Portanguen, Mohamed Hammadi, Pierre-Guy Marnet. Oxytocin and cortisol release during suckling, hand-milking and machine milking in camels.
The Journal of dairy research.
2021 Aug; 88(3):278-285. doi:
10.1017/s0022029921000522. [PMID: 34289918] - Megan Galbally, Stuart J Watson, Jeffrey A Keelan, Olav Spigset, Andrew Lewis. The relationship between oxytocin blood concentrations and antidepressants over pregnancy and the postpartum.
Progress in neuro-psychopharmacology & biological psychiatry.
2021 07; 109(?):110218. doi:
10.1016/j.pnpbp.2020.110218. [PMID: 33346016] - Mirta Kadivnik, Željko Debeljak, Dario Mandić, Jasenka Wagner, Kristina Kralik, Siniša Šijanović, Andrijana Muller, Vatroslav Šerić. Requirement for oxytocin augmentation in spontaneous parturition is associated with the maternal serum steroid hormones assessed by liquid chromatography coupled to the tandem mass spectrometry.
The journal of obstetrics and gynaecology research.
2021 Jul; 47(7):2347-2355. doi:
10.1111/jog.14792. [PMID: 33855759] - Sofia I Cardenas, Sarah A Stoycos, Pia Sellery, Narcis Marshall, Hannah Khoddam, Jonas Kaplan, Diane Goldenberg, Darby E Saxbe. Theory of mind processing in expectant fathers: Associations with prenatal oxytocin and parental attunement.
Developmental psychobiology.
2021 07; 63(5):1549-1567. doi:
10.1002/dev.22115. [PMID: 33748973] - Vimala N Bharadwaj, Frank Porreca, Robert P Cowan, Shashidhar Kori, Stephen D Silberstein, David C Yeomans. A new hypothesis linking oxytocin to menstrual migraine.
Headache.
2021 07; 61(7):1051-1059. doi:
10.1111/head.14152. [PMID: 34125955] - Rick Roels, Uzma S Rehman, C Sue Carter, Hossein P Nazarloo, Erick Janssen. The link between oxytocin plasma levels and observed communication behaviors during sexual and nonsexual couple discussions: An exploratory study.
Psychoneuroendocrinology.
2021 07; 129(?):105265. doi:
10.1016/j.psyneuen.2021.105265. [PMID: 34023731]