p,p-DDE (BioDeep_00001867765)
Main id: BioDeep_00000003277
代谢物信息卡片
p,p-DDE
化学式: C14H8Cl4 (315.938)
中文名称: p, p’-DDE, 2，2-双（4-氯苯基）-1，1-二氯乙烯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C(=C(Cl)Cl)C2=CC=C(C=C2)Cl)Cl
InChI: InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
13 个数据库交叉引用编号
- ChEBI: CHEBI:16598
- KEGG: C04596
- KEGGdrug: D88610
- PubChem: 3035
- ChEMBL: CHEMBL363207
- MeSH: Dichlorodiphenyl Dichloroethylene
- CAS: 68679-99-2
- CAS: 72-55-9
- PubChem: 7193
- PDB-CCD: 6WS
- 3DMET: B00737
- NIKKAJI: J2.817G
- KNApSAcK: 16598
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bruna Rubbo, Zhenjiang Li, Phum Tachachartvanich, Brittney O Baumert, Hongxu Wang, Shudi Pan, Sarah Rock, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Xiangping Lin, Scott Bartell, Thomas H Inge, Stavra Xanthakos, Brooklynn McNeil, Anna R Robuck, Michele A La Merrill, Douglas I Walker, David V Conti, Rob McConnell, Sandrah P Eckel, Lida Chatzi. Exposure to 4,4'-DDE in visceral adipose tissue and weight loss in adolescents from the Teen-LABS cohort.
Obesity (Silver Spring, Md.).
2024 May; 32(5):1023-1032. doi:
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Chemosphere.
2024 Feb; 349(?):140883. doi:
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The Science of the total environment.
2023 Oct; 908(?):168096. doi:
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Chemosphere.
2023 Oct; 338(?):139600. doi:
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2022 07; 33(4):505-513. doi:
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Molecular pharmaceutics.
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Environmental toxicology and chemistry.
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Lupus.
2021 Dec; 30(14):2204-2212. doi:
10.1177/09612033211051947. [PMID: 34677112] - Yao Zheng, Lei Lei, Shuai Liang, Jiao Ai, Xin Deng, Yan-Qiu Li, Tian-Pei Zhang, Shi-Biao Pu, Yong-Shen Ren. Protective Effect of Fresh/Dry Dandelion Extracts on APAP-Overdose-Induced Acute Liver Injury.
Chinese journal of integrative medicine.
2021 Nov; ?(?):. doi:
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2021 10; 36(10):3067-3075. doi:
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Diabetes & metabolism.
2021 09; 47(5):101234. doi:
10.1016/j.diabet.2021.101234. [PMID: 33515717] - Mahmut Kemal Korucu, Pınar Sevim Elibol, Mehmet Isleyen. An environmental risk assessment for a DDX-contaminated agricultural area in Turkey: soil vs. plant or human vs. animal.
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2021 Sep; 28(36):50127-50140. doi:
10.1007/s11356-021-14154-4. [PMID: 33948847] - Iva Kladnicka, Miroslava Cedikova, Jan Jedlicka, Michaela Kohoutova, Ludek Muller, Iveta Plavinova, Michaela Kripnerova, Monika Bludovska, Jitka Kuncova, Dana Mullerova. Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes.
Biomolecules.
2021 07; 11(8):. doi:
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International journal of hygiene and environmental health.
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Ecotoxicology and environmental safety.
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PloS one.
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Lipids in health and disease.
2020 Dec; 19(1):249. doi:
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Ecotoxicology and environmental safety.
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Chemosphere.
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Reproductive toxicology (Elmsford, N.Y.).
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Ecotoxicology and environmental safety.
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Reproductive toxicology (Elmsford, N.Y.).
2020 03; 92(?):129-137. doi:
10.1016/j.reprotox.2019.05.059. [PMID: 31102720] - Noelia Morales-Prieto, Nieves López de Lerma, Isabel L Pacheco, Paula V Huertas-Abril, José Pérez, Rafael Peinado, Nieves Abril. Protective effect of Pedro-Ximénez must against p,p'-DDE-induced liver damages in aged Mus spretus mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Feb; 136(?):110984. doi:
10.1016/j.fct.2019.110984. [PMID: 31765701] - Laurent Brureau, Elise Emeville, Carole Helissey, Jean Pierre Thome, Luc Multigner, Pascal Blanchet. Endocrine disrupting-chemicals and biochemical recurrence of prostate cancer after prostatectomy: A cohort study in Guadeloupe (French West Indies).
International journal of cancer.
2020 02; 146(3):657-663. doi:
10.1002/ijc.32287. [PMID: 30892691] - Jonatan Axelsson, Kristin Scott, Joakim Dillner, Christian H Lindh, He Zhang, Lars Rylander, Anna Rignell-Hydbom. Exposure to polychlorinated compounds and cryptorchidism; A nested case-control study.
PloS one.
2020; 15(7):e0236394. doi:
10.1371/journal.pone.0236394. [PMID: 32702712] - Michail Barmpas, Elena Vakonaki, Manolis Tzatzarakis, Stavros Sifakis, Athanasios Alegakis, Themos Grigoriadis, Danielle Bittencourt Sodré, Georgios Daskalakis, Aristidis Antsaklis, Aristidis Tsatsakis. Organochlorine pollutants' levels in hair, amniotic fluid and serum samples of pregnant women in Greece. A cohort study.
Environmental toxicology and pharmacology.
2020 Jan; 73(?):103279. doi:
10.1016/j.etap.2019.103279. [PMID: 31704585] - Lindsay M Jaacks, Sudesh Yadav, Parinya Panuwet, Sushil Kumar, Girish H Rajacharya, Cierra Johnson, Ishita Rawal, Deepa Mohan, Viswanathan Mohan, Nikhil Tandon, Dana Boyd Barr, K M Venkat Narayan, Dorairaj Prabhakaran. Metabolite of the pesticide DDT and incident type 2 diabetes in urban India.
Environment international.
2019 12; 133(Pt A):105089. doi:
10.1016/j.envint.2019.105089. [PMID: 31654984] - Parisa Paydar, Gholamreza Asadikaram, Hossein Fallah, Hamid Zeynali Nejad, Hamed Akbari, Moslem Abolhassani, Vahid Moazed, Payam Khazaeli, Mahmoud Reza Heidari. Serum levels of Organochlorine Pesticides and Breast Cancer Risk in Iranian Women.
Archives of environmental contamination and toxicology.
2019 Nov; 77(4):480-489. doi:
10.1007/s00244-019-00648-3. [PMID: 31324944] - Gema Rodríguez-Moro, Nieves Abril, Rocío Jara-Biedma, Sara Ramírez-Acosta, José Luis Gómez-Ariza, Tamara García-Barrera. Metabolic Impairments Caused by a 'Chemical Cocktail' of DDE and Selenium in Mice Using Direct Infusion Triple Quadrupole Time-of-Flight and Gas Chromatography-Mass Spectrometry.
Chemical research in toxicology.
2019 10; 32(10):1940-1954. doi:
10.1021/acs.chemrestox.9b00102. [PMID: 31532635] - Jonathan Chevrier, Stephen Rauch, Muvhulawa Obida, Madelein Crause, Riana Bornman, Brenda Eskenazi. Sex and poverty modify associations between maternal peripartum concentrations of DDT/E and pyrethroid metabolites and thyroid hormone levels in neonates participating in the VHEMBE study, South Africa.
Environment international.
2019 10; 131(?):104958. doi:
10.1016/j.envint.2019.104958. [PMID: 31284115] - Jing Zhan, Yiran Liang, Donghui Liu, Xiaoran Ma, Peize Li, Wangjing Zhai, Zhiqiang Zhou, Peng Wang. Pectin reduces environmental pollutant-induced obesity in mice through regulating gut microbiota: A case study of p,p'-DDE.
Environment international.
2019 09; 130(?):104861. doi:
10.1016/j.envint.2019.05.055. [PMID: 31195221] - Sujin Kim, Yoon Hee Cho, Sungho Won, Ja-Lok Ku, Hyo-Bang Moon, Jeongim Park, Gyuyeon Choi, Sungkyoon Kim, Kyungho Choi. Maternal exposures to persistent organic pollutants are associated with DNA methylation of thyroid hormone-related genes in placenta differently by infant sex.
Environment international.
2019 09; 130(?):104956. doi:
10.1016/j.envint.2019.104956. [PMID: 31272017] - Moslem Abolhassani, Gholamreza Asadikaram, Parisa Paydar, Hossein Fallah, Mahmood Aghaee-Afshar, Vahid Moazed, Hamed Akbari, Sodaif Darvish Moghaddam, Afshin Moradi. Organochlorine and organophosphorous pesticides may induce colorectal cancer; A case-control study.
Ecotoxicology and environmental safety.
2019 Aug; 178(?):168-177. doi:
10.1016/j.ecoenv.2019.04.030. [PMID: 31004929] - Marija Dvoršćak, Sanja Stipičević, Gordana Mendaš, Vlasta Drevenkar, Gordana Medunić, Zvjezdana Stančić, Dinko Vujević. Soil burden by persistent organochlorine compounds in the vicinity of a coal-fired power plant in Croatia: a comparison study with an urban-industrialized area.
Environmental science and pollution research international.
2019 Aug; 26(23):23707-23716. doi:
10.1007/s11356-019-05605-0. [PMID: 31203553] - Barbara A Cohn, Piera M Cirillo, Mary Beth Terry. DDT and Breast Cancer: Prospective Study of Induction Time and Susceptibility Windows.
Journal of the National Cancer Institute.
2019 08; 111(8):803-810. doi:
10.1093/jnci/djy198. [PMID: 30759253] - Andreas Tornevi, Johan Sommar, Panu Rantakokko, Agneta Åkesson, Carolina Donat-Vargas, Hannu Kiviranta, Olov Rolandsson, Lars Rylander, Maria Wennberg, Ingvar A Bergdahl. Chlorinated persistent organic pollutants and type 2 diabetes - A population-based study with pre- and post- diagnostic plasma samples.
Environmental research.
2019 07; 174(?):35-45. doi:
10.1016/j.envres.2019.04.017. [PMID: 31029940] - Wendy A Wattigney, Elizabeth Irvin-Barnwell, Zheng Li, Angela Ragin-Wilson. Biomonitoring of mercury and persistent organic pollutants in Michigan urban anglers and association with fish consumption.
International journal of hygiene and environmental health.
2019 07; 222(6):936-944. doi:
10.1016/j.ijheh.2019.06.007. [PMID: 31257185] - Kavita Singh, Subramanian Karthikeyan, Djordje Vladisavljevic, Annie St-Amand, Hing Man Chan. Factors associated with plasma concentrations of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (p,p'-DDE) in the Canadian population.
International journal of environmental health research.
2019 Jun; 29(3):326-347. doi:
10.1080/09603123.2018.1543799. [PMID: 30431336] - H Bouwman, Y B Yohannes, S M M Nakayama, K Motohira, M Ishizuka, M S Humphries, V van der Schyff, M du Preez, A Dinkelmann, Y Ikenaka. Evidence of impacts from DDT in pelican, cormorant, stork, and egret eggs from KwaZulu-Natal, South Africa.
Chemosphere.
2019 Jun; 225(?):647-658. doi:
10.1016/j.chemosphere.2019.03.043. [PMID: 30901658] - Nicholas A Warner, Kjetil Sagerup, Siv Kristoffersen, Dorte Herzke, Geir W Gabrielsen, Bjørn M Jenssen. Snow buntings (Plectrophenax nivealis) as bio-indicators for exposure differences to legacy and emerging persistent organic pollutants from the Arctic terrestrial environment on Svalbard.
The Science of the total environment.
2019 Jun; 667(?):638-647. doi:
10.1016/j.scitotenv.2019.02.351. [PMID: 30833262] - Vincenzo Migliaccio, Raffaella Sica, Rosaria Scudiero, Palma Simoniello, Rosalba Putti, Lillà Lionetti. Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Wistar Rat Testis.
Cells.
2019 05; 8(5):. doi:
10.3390/cells8050443. [PMID: 31083466] - Humberto Parada, Xuezheng Sun, Chiu-Kit Tse, Lawrence S Engel, Andrew F Olshan, Melissa A Troester. Plasma levels of dichlorodiphenyldichloroethene (DDE) and dichlorodiphenyltrichloroethane (DDT) and survival following breast cancer in the Carolina Breast Cancer Study.
Environment international.
2019 04; 125(?):161-171. doi:
10.1016/j.envint.2019.01.032. [PMID: 30716576] - Vincenzo Migliaccio, Lillà Lionetti, Rosalba Putti, Raffaella Sica, Rosaria Scudiero. Combined effects of DDE and hyperlipidic diet on metallothionein expression and synthesis in rat tissues.
Environmental toxicology.
2019 Mar; 34(3):283-293. doi:
10.1002/tox.22683. [PMID: 30575243] - Saroj Jayasinghe, Lars Lind, Samira Salihovic, Anders Larsson, P Monica Lind. DDT and its metabolites could contribute to the aetiology of chronic kidney disease of unknown aetiology (CKDu) and more studies are a priority.
The Science of the total environment.
2019 02; 649(?):1638-1639. doi:
10.1016/j.scitotenv.2018.09.116. [PMID: 30227991] - Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers. Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi.
Journal of toxicology and environmental health. Part A.
2019; 82(6):387-400. doi:
10.1080/15287394.2019.1610678. [PMID: 31064277] - Vincenzo Migliaccio, Rosaria Scudiero, Raffaella Sica, Lillà Lionetti, Rosalba Putti. Oxidative stress and mitochondrial uncoupling protein 2 expression in hepatic steatosis induced by exposure to xenobiotic DDE and high fat diet in male Wistar rats.
PloS one.
2019; 14(4):e0215955. doi:
10.1371/journal.pone.0215955. [PMID: 31022254] - Saroj Jayasinghe, Lars Lind, Samira Salihovic, Anders Larsson, P Monica Lind. High serum levels of p,p'-DDE are associated with an accelerated decline in GFR during 10 years follow-up.
The Science of the total environment.
2018 Dec; 644(?):371-374. doi:
10.1016/j.scitotenv.2018.07.020. [PMID: 29981985] - Li Wang, Cheng Xue, Yushu Zhang, Zhiguo Li, Chuang Liu, Xia Pan, Fang Chen, Yi Liu. Soil aggregate-associated distribution of DDTs and HCHs in farmland and bareland soils in the Danjiangkou Reservoir Area of China.
Environmental pollution (Barking, Essex : 1987).
2018 Dec; 243(Pt A):734-742. doi:
10.1016/j.envpol.2018.09.019. [PMID: 30228065] - Vivian Berg, Therese Haugdahl Nøst, Torkjel Manning Sandanger, Charlotta Rylander. Predicting human plasma concentrations of persistent organic pollutants from dietary intake and socio-demographic information in the Norwegian Women and Cancer study.
Environment international.
2018 12; 121(Pt 2):1311-1318. doi:
10.1016/j.envint.2018.10.057. [PMID: 30415879] - Marc-André Verner, Jonathan Chevrier, Gérard Ngueta, Stephen Rauch, Riana Bornman, Brenda Eskenazi. Early-life exposure to p,p'-DDT and p,p'-DDE in South African children participating in the VHEMBE study: An assessment using repeated serum measurements and pharmacokinetic modeling.
Environment international.
2018 10; 119(?):478-484. doi:
10.1016/j.envint.2018.07.010. [PMID: 30036731] - José Alhama, Carlos A Fuentes-Almagro, Nieves Abril, Carmen Michán. Alterations in oxidative responses and post-translational modification caused by p,p´-DDE in Mus spretus testes reveal Cys oxidation status in proteins related to cell-redox homeostasis and male fertility.
The Science of the total environment.
2018 Sep; 636(?):656-669. doi:
10.1016/j.scitotenv.2018.04.305. [PMID: 29723838] - Juan Pedro Arrebola, Argelia Castaño, Marta Esteban, Mónica Bartolomé, Beatriz Pérez-Gómez, Juan José Ramos. Differential contribution of animal and vegetable food items on persistent organic pollutant serum concentrations in Spanish adults. Data from BIOAMBIENT.ES project.
The Science of the total environment.
2018 Sep; 634(?):235-242. doi:
10.1016/j.scitotenv.2018.03.283. [PMID: 29627546] - George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes.
Environmental toxicology.
2018 Sep; 33(9):962-971. doi:
10.1002/tox.22583. [PMID: 29964320] - Ana Paula Moreno Barbosa, Paula Méndez-Fernandez, Patrick Simões Dias, Marcos César Oliveira Santos, Satie Taniguchi, Rosalinda Carmela Montone. Transplacental transfer of persistent organic pollutants in La Plata dolphins (Pontoporia blainvillei; Cetartiodactyla, Pontoporiidae).
The Science of the total environment.
2018 Aug; 631-632(?):239-245. doi:
10.1016/j.scitotenv.2018.02.325. [PMID: 29524899] - Jie Wang, Allison Taylor, Chenye Xu, Daniel Schlenk, Jay Gan. Evaluation of different methods for assessing bioavailability of DDT residues during soil remediation.
Environmental pollution (Barking, Essex : 1987).
2018 Jul; 238(?):462-470. doi:
10.1016/j.envpol.2018.02.082. [PMID: 29587217] - Tanya M Brown, Sarah I Lord, David W Schindler, John E Elliott. Organohalogen contaminants in common loons (Gavia immer) breeding in Western Alberta, Canada.
Chemosphere.
2018 Jul; 202(?):438-445. doi:
10.1016/j.chemosphere.2018.03.107. [PMID: 29579678] - Rehnuma Haque, Tsukasa Inaoka, Miho Fujimura, Chiho Watanabe, Akhtar Sk Ahmad, Risa Kakimoto, Momoko Ishiyama, Daisuke Ueno. Dietary patterns and serum of DDT concentrations among reproductive-aged group of women in Bangladesh.
Environmental science and pollution research international.
2018 Jun; 25(18):17665-17673. doi:
10.1007/s11356-018-1958-6. [PMID: 29667061] - B González-Alzaga, M Lacasaña, A F Hernández, J P Arrebola, I López-Flores, F Artacho-Cordón, J P Bonde, N Olea, C Aguilar-Garduño. Serum concentrations of organochlorine compounds and predictors of exposure in children living in agricultural communities from South-Eastern Spain.
Environmental pollution (Barking, Essex : 1987).
2018 Jun; 237(?):685-694. doi:
10.1016/j.envpol.2017.10.109. [PMID: 29129429] - Jonathan Huang, Brenda Eskenazi, Riana Bornman, Stephen Rauch, Jonathan Chevrier. Maternal Peripartum Serum DDT/E and Urinary Pyrethroid Metabolite Concentrations and Child Infections at 2 Years in the VHEMBE Birth Cohort.
Environmental health perspectives.
2018 06; 126(6):067006. doi:
10.1289/ehp2657. [PMID: 29906263] - Mireille Harmouche-Karaki, Joseph Matta, Khalil Helou, Yara Mahfouz, Nicole Fakhoury-Sayegh, Jean-François Narbonne. Serum concentrations of selected organochlorine pesticides in a Lebanese population and their associations to sociodemographic, anthropometric and dietary factors: ENASB study.
Environmental science and pollution research international.
2018 May; 25(15):14350-14360. doi:
10.1007/s11356-017-9427-1. [PMID: 28616737] - Aina Jansen, Anuschka Polder, Mette H B Müller, Eystein Skjerve, Jan Aaseth, Jan L Lyche. Increased levels of persistent organic pollutants in serum one year after a great weight loss in humans: Are the levels exceeding health based guideline values?.
The Science of the total environment.
2018 May; 622-623(?):1317-1326. doi:
10.1016/j.scitotenv.2017.11.241. [PMID: 29890598] - Jiaxin Li, Pengsi Wang, Shangmei Shi, Jian Xue. Background biomonitoring of residue levels of 137 pesticides in the blood plasma of the general population in Beijing.
Environmental monitoring and assessment.
2018 Apr; 190(5):315. doi:
10.1007/s10661-018-6694-3. [PMID: 29705822] - Jennifer Murray, Brenda Eskenazi, Riana Bornman, Fraser W Gaspar, Madelein Crause, Muvhulawa Obida, Jonathan Chevrier. Exposure to DDT and hypertensive disorders of pregnancy among South African women from an indoor residual spraying region: The VHEMBE study.
Environmental research.
2018 04; 162(?):49-54. doi:
10.1016/j.envres.2017.12.006. [PMID: 29287179] - Maria Bornman, Rhena Delport, Paulina Farías, Natalie Aneck-Hahn, Sean Patrick, Robert P Millar, Christiaan de Jager. Alterations in male reproductive hormones in relation to environmental DDT exposure.
Environment international.
2018 04; 113(?):281-289. doi:
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