p,p-DDE (BioDeep_00001867765)
Main id: BioDeep_00000003277
代谢物信息卡片
化学式: C14H8Cl4 (315.93800880000003)
中文名称: p, p’-DDE
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C(=C(Cl)Cl)C2=CC=C(C=C2)Cl)Cl
InChI: InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:16598
- KEGG: C04596
- KEGGdrug: D88610
- PubChem: 3035
- ChEMBL: CHEMBL363207
- MeSH: Dichlorodiphenyl Dichloroethylene
- CAS: 68679-99-2
- CAS: 72-55-9
- PubChem: 7193
- PDB-CCD: 6WS
- 3DMET: B00737
- NIKKAJI: J2.817G
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Bruna Rubbo, Zhenjiang Li, Phum Tachachartvanich, Brittney O Baumert, Hongxu Wang, Shudi Pan, Sarah Rock, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Xiangping Lin, Scott Bartell, Thomas H Inge, Stavra Xanthakos, Brooklynn McNeil, Anna R Robuck, Michele A La Merrill, Douglas I Walker, David V Conti, Rob McConnell, Sandrah P Eckel, Lida Chatzi. Exposure to 4,4'-DDE in visceral adipose tissue and weight loss in adolescents from the Teen-LABS cohort.
Obesity (Silver Spring, Md.).
2024 May; 32(5):1023-1032. doi:
10.1002/oby.24009
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Chemosphere.
2024 Feb; 349(?):140883. doi:
10.1016/j.chemosphere.2023.140883
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The Science of the total environment.
2023 Oct; 908(?):168096. doi:
10.1016/j.scitotenv.2023.168096
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Chemosphere.
2023 Oct; 338(?):139600. doi:
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Environment international.
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Environmental pollution (Barking, Essex : 1987).
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Environmental research.
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Epidemiology (Cambridge, Mass.).
2022 07; 33(4):505-513. doi:
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2022 May; 821(?):153447. doi:
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Molecular pharmaceutics.
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. [PMID: 35357154] - Mekuria Teshome Mergia, Ermias Deribe Weldemariam, Ole Martin Eklo, Girma Tilahun Yimer. Levels and Trophic Transfer of Selected Pesticides in the Lake Ziway Ecosystem.
Bulletin of environmental contamination and toxicology.
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Environment international.
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. [PMID: 35303528] - Wen-Lu Feng, Jiang-Ping Wu, Xiao Li, You-Tian Nie, Ya-Chun Xu, Lin Tao, Yan-Hong Zeng, Xiao-Jun Luo, Bi-Xian Mai. Bioaccumulation and maternal transfer of two understudied DDT metabolites in wild fish species.
The Science of the total environment.
2022 Apr; 818(?):151814. doi:
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. [PMID: 34813814] - Aisha S Dickerson, Zhengyi Deng, Yusuf Ransome, Pam Factor-Litvak, Oskar Karlsson. Associations of prenatal exposure to mixtures of organochlorine pesticides and smoking and drinking behaviors in adolescence.
Environmental research.
2022 04; 206(?):112431. doi:
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. [PMID: 34848208] - Mireille Harmouche-Karaki, Maya Mahfouz, Khalil Helou, Jawaher Obeyd, Pascale Salameh, Joseph Matta, Jean-François Narbonne. Association between dietary quality indices and serum polychlorinated biphenyls and organochlorine pesticides levels among Lebanese adults.
Environmental science and pollution research international.
2022 Apr; 29(19):28402-28413. doi:
10.1007/s11356-021-17924-2
. [PMID: 34988801] - Erica M Molina, Andreas N Kavazis, Mary T Mendonça, Benson T Akingbemi. Effects of different DDE exposure paradigms on testicular steroid hormone secretion and hepatic oxidative stress in male Long-Evans rats.
General and comparative endocrinology.
2022 02; 317(?):113963. doi:
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Pediatric research.
2022 02; 91(3):690-698. doi:
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. [PMID: 33824444] - Su-Su Wang, An-Xin Lu, Lu-Lu Cao, Xiu-Fang Ran, Ya-Qian Wang, Chen Liu, Chong-Huai Yan. Effects of prenatal exposure to persistent organic pollutants on neonatal Outcomes:A mother-child cohort (Shanghai, China).
Environmental research.
2022 01; 203(?):111767. doi:
10.1016/j.envres.2021.111767
. [PMID: 34391732] - Robert Kesic, John E Elliott, Kate M Fremlin, Lewis Gauthier, Kenneth G Drouillard, Christine A Bishop. Continuing Persistence and Biomagnification of DDT and Metabolites in Northern Temperate Fruit Orchard Avian Food Chains.
Environmental toxicology and chemistry.
2021 12; 40(12):3379-3391. doi:
10.1002/etc.5220
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Lupus.
2021 Dec; 30(14):2204-2212. doi:
10.1177/09612033211051947
. [PMID: 34677112] - Yao Zheng, Lei Lei, Shuai Liang, Jiao Ai, Xin Deng, Yan-Qiu Li, Tian-Pei Zhang, Shi-Biao Pu, Yong-Shen Ren. Protective Effect of Fresh/Dry Dandelion Extracts on APAP-Overdose-Induced Acute Liver Injury.
Chinese journal of integrative medicine.
2021 Nov; ?(?):. doi:
10.1007/s11655-021-3295-8
. [PMID: 34816363] - Elizabeth Velan, Barbara Sheller. Oral health in children with chronic kidney disease.
Pediatric nephrology (Berlin, Germany).
2021 10; 36(10):3067-3075. doi:
10.1007/s00467-020-04913-9
. [PMID: 33528633] - Richelle D Björvang, Jasmin Hassan, Maria Stefopoulou, Kristina Gemzell-Danielsson, Matteo Pedrelli, Hannu Kiviranta, Panu Rantakokko, Päivi Ruokojärvi, Christian H Lindh, Ganesh Acharya, Pauliina Damdimopoulou. Persistent organic pollutants and the size of ovarian reserve in reproductive-aged women.
Environment international.
2021 10; 155(?):106589. doi:
10.1016/j.envint.2021.106589
. [PMID: 33945905] - Dianna J Magliano, Fanny Rancière, Rémy Slama, Ronan Roussel, Hannu Kiviranta, Xavier Coumoul, Beverley Balkau, Jérémie Botton. Exposure to persistent organic pollutants and the risk of type 2 diabetes: a case-cohort study.
Diabetes & metabolism.
2021 09; 47(5):101234. doi:
10.1016/j.diabet.2021.101234
. [PMID: 33515717] - Mahmut Kemal Korucu, Pınar Sevim Elibol, Mehmet Isleyen. An environmental risk assessment for a DDX-contaminated agricultural area in Turkey: soil vs. plant or human vs. animal.
Environmental science and pollution research international.
2021 Sep; 28(36):50127-50140. doi:
10.1007/s11356-021-14154-4
. [PMID: 33948847] - Iva Kladnicka, Miroslava Cedikova, Jan Jedlicka, Michaela Kohoutova, Ludek Muller, Iveta Plavinova, Michaela Kripnerova, Monika Bludovska, Jitka Kuncova, Dana Mullerova. Chronic DDE Exposure Modifies Mitochondrial Respiration during Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Mature Adipocytes.
Biomolecules.
2021 07; 11(8):. doi:
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International journal of hygiene and environmental health.
2021 07; 236(?):113801. doi:
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. [PMID: 34243000] - Shushu Li, Wei Shao, Chao Wang, Li Wang, Rong Xia, Shen Yao, Mulong Du, Xiaoming Ji, Haiyan Chu, Zhengdong Zhang, Meilin Wang, Shou-Lin Wang. Identification of common genetic variants associated with serum concentrations of p, p'-DDE in non-occupational populations in eastern China.
Environment international.
2021 07; 152(?):106507. doi:
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Environment international.
2021 02; 147(?):106318. doi:
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Ecotoxicology and environmental safety.
2021 Jan; 208(?):111479. doi:
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PloS one.
2021; 16(9):e0257704. doi:
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Lipids in health and disease.
2020 Dec; 19(1):249. doi:
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Ecotoxicology and environmental safety.
2020 Dec; 205(?):111331. doi:
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Environmental research.
2020 12; 191(?):110088. doi:
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Environment international.
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Environment international.
2020 11; 144(?):106037. doi:
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Environmental research.
2020 10; 189(?):109905. doi:
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International journal of hygiene and environmental health.
2020 07; 228(?):113527. doi:
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Environmental research.
2020 07; 186(?):109439. doi:
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Environmental research.
2020 06; 185(?):109366. doi:
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Environmental research.
2020 05; 184(?):109352. doi:
10.1016/j.envres.2020.109352
. [PMID: 32182481] - Yiran Liang, Donghui Liu, Jing Zhan, Mai Luo, Jiajun Han, Peng Wang, Zhiqiang Zhou. New insight into the mechanism of POP-induced obesity: Evidence from DDE-altered microbiota.
Chemosphere.
2020 Apr; 244(?):125123. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2020 03; 92(?):112-119. doi:
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. [PMID: 31323350] - Xu Han, Feng Zhang, Lingling Meng, Yuedong Xu, Yingming Li, An Li, Mary E Turyk, Ruiqiang Yang, Pu Wang, Jianqing Zhang, Qinghua Zhang, Guibin Jiang. Exposure to organochlorine pesticides and the risk of type 2 diabetes in the population of East China.
Ecotoxicology and environmental safety.
2020 Mar; 190(?):110125. doi:
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. [PMID: 31887706] - J A Rusiecki, H Denic-Roberts, C Byrne, J Cash, C F Raines, L A Brinton, S H Zahm, T Mason, M R Bonner, A Blair, R Hoover. Serum concentrations of DDE, PCBs, and other persistent organic pollutants and mammographic breast density in Triana, Alabama, a highly exposed population.
Environmental research.
2020 03; 182(?):109068. doi:
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Reproductive toxicology (Elmsford, N.Y.).
2020 03; 92(?):129-137. doi:
10.1016/j.reprotox.2019.05.059
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Feb; 136(?):110984. doi:
10.1016/j.fct.2019.110984
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International journal of cancer.
2020 02; 146(3):657-663. doi:
10.1002/ijc.32287
. [PMID: 30892691] - Jonatan Axelsson, Kristin Scott, Joakim Dillner, Christian H Lindh, He Zhang, Lars Rylander, Anna Rignell-Hydbom. Exposure to polychlorinated compounds and cryptorchidism; A nested case-control study.
PloS one.
2020; 15(7):e0236394. doi:
10.1371/journal.pone.0236394
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Environmental toxicology and pharmacology.
2020 Jan; 73(?):103279. doi:
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Environment international.
2019 12; 133(Pt A):105089. doi:
10.1016/j.envint.2019.105089
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Archives of environmental contamination and toxicology.
2019 Nov; 77(4):480-489. doi:
10.1007/s00244-019-00648-3
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Chemical research in toxicology.
2019 10; 32(10):1940-1954. doi:
10.1021/acs.chemrestox.9b00102
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Environment international.
2019 10; 131(?):104958. doi:
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Environment international.
2019 09; 130(?):104861. doi:
10.1016/j.envint.2019.05.055
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Environment international.
2019 09; 130(?):104956. doi:
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Ecotoxicology and environmental safety.
2019 Aug; 178(?):168-177. doi:
10.1016/j.ecoenv.2019.04.030
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Environmental science and pollution research international.
2019 Aug; 26(23):23707-23716. doi:
10.1007/s11356-019-05605-0
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Journal of the National Cancer Institute.
2019 08; 111(8):803-810. doi:
10.1093/jnci/djy198
. [PMID: 30759253] - Andreas Tornevi, Johan Sommar, Panu Rantakokko, Agneta Åkesson, Carolina Donat-Vargas, Hannu Kiviranta, Olov Rolandsson, Lars Rylander, Maria Wennberg, Ingvar A Bergdahl. Chlorinated persistent organic pollutants and type 2 diabetes - A population-based study with pre- and post- diagnostic plasma samples.
Environmental research.
2019 07; 174(?):35-45. doi:
10.1016/j.envres.2019.04.017
. [PMID: 31029940] - Wendy A Wattigney, Elizabeth Irvin-Barnwell, Zheng Li, Angela Ragin-Wilson. Biomonitoring of mercury and persistent organic pollutants in Michigan urban anglers and association with fish consumption.
International journal of hygiene and environmental health.
2019 07; 222(6):936-944. doi:
10.1016/j.ijheh.2019.06.007
. [PMID: 31257185] - Kavita Singh, Subramanian Karthikeyan, Djordje Vladisavljevic, Annie St-Amand, Hing Man Chan. Factors associated with plasma concentrations of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (p,p'-DDE) in the Canadian population.
International journal of environmental health research.
2019 Jun; 29(3):326-347. doi:
10.1080/09603123.2018.1543799
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Chemosphere.
2019 Jun; 225(?):647-658. doi:
10.1016/j.chemosphere.2019.03.043
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The Science of the total environment.
2019 Jun; 667(?):638-647. doi:
10.1016/j.scitotenv.2019.02.351
. [PMID: 30833262] - Vincenzo Migliaccio, Raffaella Sica, Rosaria Scudiero, Palma Simoniello, Rosalba Putti, Lillà Lionetti. Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Wistar Rat Testis.
Cells.
2019 05; 8(5):. doi:
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. [PMID: 31083466] - Humberto Parada, Xuezheng Sun, Chiu-Kit Tse, Lawrence S Engel, Andrew F Olshan, Melissa A Troester. Plasma levels of dichlorodiphenyldichloroethene (DDE) and dichlorodiphenyltrichloroethane (DDT) and survival following breast cancer in the Carolina Breast Cancer Study.
Environment international.
2019 04; 125(?):161-171. doi:
10.1016/j.envint.2019.01.032
. [PMID: 30716576] - Vincenzo Migliaccio, Lillà Lionetti, Rosalba Putti, Raffaella Sica, Rosaria Scudiero. Combined effects of DDE and hyperlipidic diet on metallothionein expression and synthesis in rat tissues.
Environmental toxicology.
2019 Mar; 34(3):283-293. doi:
10.1002/tox.22683
. [PMID: 30575243] - Saroj Jayasinghe, Lars Lind, Samira Salihovic, Anders Larsson, P Monica Lind. DDT and its metabolites could contribute to the aetiology of chronic kidney disease of unknown aetiology (CKDu) and more studies are a priority.
The Science of the total environment.
2019 02; 649(?):1638-1639. doi:
10.1016/j.scitotenv.2018.09.116
. [PMID: 30227991] - Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers. Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi.
Journal of toxicology and environmental health. Part A.
2019; 82(6):387-400. doi:
10.1080/15287394.2019.1610678
. [PMID: 31064277] - Vincenzo Migliaccio, Rosaria Scudiero, Raffaella Sica, Lillà Lionetti, Rosalba Putti. Oxidative stress and mitochondrial uncoupling protein 2 expression in hepatic steatosis induced by exposure to xenobiotic DDE and high fat diet in male Wistar rats.
PloS one.
2019; 14(4):e0215955. doi:
10.1371/journal.pone.0215955
. [PMID: 31022254] - Saroj Jayasinghe, Lars Lind, Samira Salihovic, Anders Larsson, P Monica Lind. High serum levels of p,p'-DDE are associated with an accelerated decline in GFR during 10 years follow-up.
The Science of the total environment.
2018 Dec; 644(?):371-374. doi:
10.1016/j.scitotenv.2018.07.020
. [PMID: 29981985] - Li Wang, Cheng Xue, Yushu Zhang, Zhiguo Li, Chuang Liu, Xia Pan, Fang Chen, Yi Liu. Soil aggregate-associated distribution of DDTs and HCHs in farmland and bareland soils in the Danjiangkou Reservoir Area of China.
Environmental pollution (Barking, Essex : 1987).
2018 Dec; 243(Pt A):734-742. doi:
10.1016/j.envpol.2018.09.019
. [PMID: 30228065] - Vivian Berg, Therese Haugdahl Nøst, Torkjel Manning Sandanger, Charlotta Rylander. Predicting human plasma concentrations of persistent organic pollutants from dietary intake and socio-demographic information in the Norwegian Women and Cancer study.
Environment international.
2018 12; 121(Pt 2):1311-1318. doi:
10.1016/j.envint.2018.10.057
. [PMID: 30415879] - Marc-André Verner, Jonathan Chevrier, Gérard Ngueta, Stephen Rauch, Riana Bornman, Brenda Eskenazi. Early-life exposure to p,p'-DDT and p,p'-DDE in South African children participating in the VHEMBE study: An assessment using repeated serum measurements and pharmacokinetic modeling.
Environment international.
2018 10; 119(?):478-484. doi:
10.1016/j.envint.2018.07.010
. [PMID: 30036731] - José Alhama, Carlos A Fuentes-Almagro, Nieves Abril, Carmen Michán. Alterations in oxidative responses and post-translational modification caused by p,p´-DDE in Mus spretus testes reveal Cys oxidation status in proteins related to cell-redox homeostasis and male fertility.
The Science of the total environment.
2018 Sep; 636(?):656-669. doi:
10.1016/j.scitotenv.2018.04.305
. [PMID: 29723838] - Juan Pedro Arrebola, Argelia Castaño, Marta Esteban, Mónica Bartolomé, Beatriz Pérez-Gómez, Juan José Ramos. Differential contribution of animal and vegetable food items on persistent organic pollutant serum concentrations in Spanish adults. Data from BIOAMBIENT.ES project.
The Science of the total environment.
2018 Sep; 634(?):235-242. doi:
10.1016/j.scitotenv.2018.03.283
. [PMID: 29627546] - George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes.
Environmental toxicology.
2018 Sep; 33(9):962-971. doi:
10.1002/tox.22583
. [PMID: 29964320] - Ana Paula Moreno Barbosa, Paula Méndez-Fernandez, Patrick Simões Dias, Marcos César Oliveira Santos, Satie Taniguchi, Rosalinda Carmela Montone. Transplacental transfer of persistent organic pollutants in La Plata dolphins (Pontoporia blainvillei; Cetartiodactyla, Pontoporiidae).
The Science of the total environment.
2018 Aug; 631-632(?):239-245. doi:
10.1016/j.scitotenv.2018.02.325
. [PMID: 29524899] - Jie Wang, Allison Taylor, Chenye Xu, Daniel Schlenk, Jay Gan. Evaluation of different methods for assessing bioavailability of DDT residues during soil remediation.
Environmental pollution (Barking, Essex : 1987).
2018 Jul; 238(?):462-470. doi:
10.1016/j.envpol.2018.02.082
. [PMID: 29587217] - Tanya M Brown, Sarah I Lord, David W Schindler, John E Elliott. Organohalogen contaminants in common loons (Gavia immer) breeding in Western Alberta, Canada.
Chemosphere.
2018 Jul; 202(?):438-445. doi:
10.1016/j.chemosphere.2018.03.107
. [PMID: 29579678] - Rehnuma Haque, Tsukasa Inaoka, Miho Fujimura, Chiho Watanabe, Akhtar Sk Ahmad, Risa Kakimoto, Momoko Ishiyama, Daisuke Ueno. Dietary patterns and serum of DDT concentrations among reproductive-aged group of women in Bangladesh.
Environmental science and pollution research international.
2018 Jun; 25(18):17665-17673. doi:
10.1007/s11356-018-1958-6
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Environmental pollution (Barking, Essex : 1987).
2018 Jun; 237(?):685-694. doi:
10.1016/j.envpol.2017.10.109
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Environmental health perspectives.
2018 06; 126(6):067006. doi:
10.1289/ehp2657
. [PMID: 29906263] - Mireille Harmouche-Karaki, Joseph Matta, Khalil Helou, Yara Mahfouz, Nicole Fakhoury-Sayegh, Jean-François Narbonne. Serum concentrations of selected organochlorine pesticides in a Lebanese population and their associations to sociodemographic, anthropometric and dietary factors: ENASB study.
Environmental science and pollution research international.
2018 May; 25(15):14350-14360. doi:
10.1007/s11356-017-9427-1
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The Science of the total environment.
2018 May; 622-623(?):1317-1326. doi:
10.1016/j.scitotenv.2017.11.241
. [PMID: 29890598] - Jiaxin Li, Pengsi Wang, Shangmei Shi, Jian Xue. Background biomonitoring of residue levels of 137 pesticides in the blood plasma of the general population in Beijing.
Environmental monitoring and assessment.
2018 Apr; 190(5):315. doi:
10.1007/s10661-018-6694-3
. [PMID: 29705822] - Jennifer Murray, Brenda Eskenazi, Riana Bornman, Fraser W Gaspar, Madelein Crause, Muvhulawa Obida, Jonathan Chevrier. Exposure to DDT and hypertensive disorders of pregnancy among South African women from an indoor residual spraying region: The VHEMBE study.
Environmental research.
2018 04; 162(?):49-54. doi:
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Environment international.
2018 04; 113(?):281-289. doi:
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